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The map label for this gene is gmhB [H]

Identifier: 227814958

GI number: 227814958

Start: 2159818

End: 2160177

Strand: Direct

Name: gmhB [H]

Synonym: BAMEG_2369

Alternate gene names: 227814958

Gene position: 2159818-2160177 (Clockwise)

Preceding gene: 227814957

Following gene: 227814959

Centisome position: 41.3

GC content: 37.5

Gene sequence:

>360_bases
ATGACAAGCATTCAAGCAATTTTCATTGATCGTGACGGTACAATTGGCGGCGACACTACAATACATTATCCAGGATCATT
TACATTATTTCCTTTTACAAAAGCATCACTGCAAAAATTAAAAGCTAATCATATAAAAGTTTTCTCTTTCACAAATCAAC
CAGGTATCGCGGATGGGATAGCGACTATAGCCGATTTTTCACAAGAATTAAAAAGCTTCGGTTTTGATGATATTTACGTA
TGTCCTCACAAACACAGTGATGGTTGTGAATGCCGGAAACCAAGTACAGGTATGCTTCTGCAAGCAGCGGAAAAACATGG
GCTTGATTTAACACAATGTGCTGTAATTGGTAATTGGTGA

Upstream 100 bases:

>100_bases
TAGAAGCTCATCCTTTTTACAAAAAATTAGGATATGAAGTAAATGGCTATCGATTTGTAAAACATTTTTAAACTACTTTT
TAATGGAAAGGACTATAACT

Downstream 100 bases:

>100_bases
TCGCTGGACTGATATTGTTGCGGGAGCAAAAGTGAATGCGACAACAATTTTAGTACGAACAGGCGCTGGATACGACGCTT
TACATACGTACCGAGACAAG

Product: hydrolase, had-superfamily, subfamily iiia

Products: L-histidinol; phosphate

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 119; Mature: 118

Protein sequence:

>119_residues
MTSIQAIFIDRDGTIGGDTTIHYPGSFTLFPFTKASLQKLKANHIKVFSFTNQPGIADGIATIADFSQELKSFGFDDIYV
CPHKHSDGCECRKPSTGMLLQAAEKHGLDLTQCAVIGNW

Sequences:

>Translated_119_residues
MTSIQAIFIDRDGTIGGDTTIHYPGSFTLFPFTKASLQKLKANHIKVFSFTNQPGIADGIATIADFSQELKSFGFDDIYV
CPHKHSDGCECRKPSTGMLLQAAEKHGLDLTQCAVIGNW
>Mature_118_residues
TSIQAIFIDRDGTIGGDTTIHYPGSFTLFPFTKASLQKLKANHIKVFSFTNQPGIADGIATIADFSQELKSFGFDDIYVC
PHKHSDGCECRKPSTGMLLQAAEKHGLDLTQCAVIGNW

Specific function: Converts the D-glycero-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=134, Percent_Identity=34.3283582089552, Blast_Score=67, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: 3.1.3.15

Molecular weight: Translated: 12996; Mature: 12865

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSIQAIFIDRDGTIGGDTTIHYPGSFTLFPFTKASLQKLKANHIKVFSFTNQPGIADGI
CCCEEEEEEECCCCCCCCCEEEECCCEEEECCCHHHHHHHCCCEEEEEEECCCCCCHHHH
ATIADFSQELKSFGFDDIYVCPHKHSDGCECRKPSTGMLLQAAEKHGLDLTQCAVIGNW
HHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCEEEEHHHCCCCEEHEEEECCC
>Mature Secondary Structure 
TSIQAIFIDRDGTIGGDTTIHYPGSFTLFPFTKASLQKLKANHIKVFSFTNQPGIADGI
CCEEEEEEECCCCCCCCCEEEECCCEEEECCCHHHHHHHCCCEEEEEEECCCCCCHHHH
ATIADFSQELKSFGFDDIYVCPHKHSDGCECRKPSTGMLLQAAEKHGLDLTQCAVIGNW
HHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCEEEEHHHCCCCEEHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-histidinol phosphate; H2O

Specific reaction: L-histidinol phosphate + H2O = L-histidinol + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11121031 [H]