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The map label for this gene is appC [H]

Identifier: 227080799

GI number: 227080799

Start: 610918

End: 611943

Strand: Reverse

Name: appC [H]

Synonym: VCM66_0576

Alternate gene names: 227080799

Gene position: 611943-610918 (Counterclockwise)

Preceding gene: 227080800

Following gene: 227080798

Centisome position: 21.16

GC content: 51.27

Gene sequence:

>1026_bases
ATGAAAGCACTTTGGAAACTCTTACGCGGCAACCGTATGGCGATGATTGGTGTCACCATCTTAGGCCTGTTTTTTCTGCT
CGCGGTCGCCGCACCACTTCTTACCTCTCATGAGCCAGACAAGCGCACGGGTAATCCGCACGAATACCCCGCTTTTGTCG
TAAAAGCGGCTAAAGCGAATCCTGATGGCTGGATTGCCGAAAACCTAGCGACAGATCGCCGCACTCTAGCGATGTCGAAA
AAAGCTGACCACATACTAGGCACCACACGTATGGGTCGTGATGTGTGGTCACAAGTGGCTTATGGTGCTCGCGTATCCTT
AGCTGTGGGCTTCGGCGCTGGTATCACGGTCTGTTTCTTAGCCACCGTCATCGGTGTCTCTGCGGGTTATTTTGGCGGGA
AAATCGACGATTTCCTCACCGCCGCAATGAACATCATGCTGGTCATTCCGCAATACCCACTGCTGTTCGTATTAGCTGCC
TTTATTGGGGAAGCGGGACCTCTCACCATAGCGCTGATTATTGGCTGTACCTCCTGGGCTTGGGGTGCGCGGGTGGTTCG
CTCGCAAACCATGGCACTGCGTGAGAAAGAGTTTGTGAAAGCCGCAGAAGTACTAGGCGAATCTTCATGGCGCATCATCT
TTATTGAGATTCTGCCAAACCTGATTTCGATTGTCGGCGCAAGTTTTATCGGTTCGGTGATGTACGCGATCATGATGGAA
GCGACGATCTCCTTCCTAGGCTTGGGCGATCCAAACACTATCAGCTGGGGCATCATGCTCTACAACGTACAAACTTCATC
TTCGATGCTGATCGGCGCTTGGTGGGAACTGCTGGCACCTTGTTTATCTTTGACTCTGCTGGTCACAGGCCTTGCGCTGT
TGAACTTTGCGGTTGACGAAATTGCTAACCCACAGTTGCGTTCACATAAAGGCATGAAGCGTTGGAAAAACCTTGCCAAG
CAAGACCAAAAAGCGCGTGAGCCAAACGTACCACCACAAAATGCACTTTGGAGCGGAGATAAATAA

Upstream 100 bases:

>100_bases
AGCTGCTGATCATGACGCTGTTCATGCTGTTCTTTAACCTGCTGGCGGACATGTTATACGTTGTTCTTGACCCTCGCTTA
CGCAAGGGAGGTAAATAATC

Downstream 100 bases:

>100_bases
TCATGACTACGCCATTAATCTCAATCCGCAACTTATGCGTGGACTACATTACCGATGCTGGTGACGTCCGTGCCTGTAAC
AATGTGAGCTTTGATTTAGC

Product: peptide ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKALWKLLRGNRMAMIGVTILGLFFLLAVAAPLLTSHEPDKRTGNPHEYPAFVVKAAKANPDGWIAENLATDRRTLAMSK
KADHILGTTRMGRDVWSQVAYGARVSLAVGFGAGITVCFLATVIGVSAGYFGGKIDDFLTAAMNIMLVIPQYPLLFVLAA
FIGEAGPLTIALIIGCTSWAWGARVVRSQTMALREKEFVKAAEVLGESSWRIIFIEILPNLISIVGASFIGSVMYAIMME
ATISFLGLGDPNTISWGIMLYNVQTSSSMLIGAWWELLAPCLSLTLLVTGLALLNFAVDEIANPQLRSHKGMKRWKNLAK
QDQKAREPNVPPQNALWSGDK

Sequences:

>Translated_341_residues
MKALWKLLRGNRMAMIGVTILGLFFLLAVAAPLLTSHEPDKRTGNPHEYPAFVVKAAKANPDGWIAENLATDRRTLAMSK
KADHILGTTRMGRDVWSQVAYGARVSLAVGFGAGITVCFLATVIGVSAGYFGGKIDDFLTAAMNIMLVIPQYPLLFVLAA
FIGEAGPLTIALIIGCTSWAWGARVVRSQTMALREKEFVKAAEVLGESSWRIIFIEILPNLISIVGASFIGSVMYAIMME
ATISFLGLGDPNTISWGIMLYNVQTSSSMLIGAWWELLAPCLSLTLLVTGLALLNFAVDEIANPQLRSHKGMKRWKNLAK
QDQKAREPNVPPQNALWSGDK
>Mature_341_residues
MKALWKLLRGNRMAMIGVTILGLFFLLAVAAPLLTSHEPDKRTGNPHEYPAFVVKAAKANPDGWIAENLATDRRTLAMSK
KADHILGTTRMGRDVWSQVAYGARVSLAVGFGAGITVCFLATVIGVSAGYFGGKIDDFLTAAMNIMLVIPQYPLLFVLAA
FIGEAGPLTIALIIGCTSWAWGARVVRSQTMALREKEFVKAAEVLGESSWRIIFIEILPNLISIVGASFIGSVMYAIMME
ATISFLGLGDPNTISWGIMLYNVQTSSSMLIGAWWELLAPCLSLTLLVTGLALLNFAVDEIANPQLRSHKGMKRWKNLAK
QDQKAREPNVPPQNALWSGDK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=308, Percent_Identity=27.2727272727273, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1787498, Length=310, Percent_Identity=30.9677419354839, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1787054, Length=243, Percent_Identity=28.8065843621399, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789889, Length=244, Percent_Identity=31.1475409836066, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789964, Length=230, Percent_Identity=34.3478260869565, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788505, Length=342, Percent_Identity=24.2690058479532, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37096; Mature: 37096

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALWKLLRGNRMAMIGVTILGLFFLLAVAAPLLTSHEPDKRTGNPHEYPAFVVKAAKAN
CHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEECCCC
PDGWIAENLATDRRTLAMSKKADHILGTTRMGRDVWSQVAYGARVSLAVGFGAGITVCFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHH
ATVIGVSAGYFGGKIDDFLTAAMNIMLVIPQYPLLFVLAAFIGEAGPLTIALIIGCTSWA
HHHHHHHCCCCCCHHHHHHHHHHHHHEECCCHHHHHHHHHHHCCCCCCEEEEEEECCCHH
WGARVVRSQTMALREKEFVKAAEVLGESSWRIIFIEILPNLISIVGASFIGSVMYAIMME
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
ATISFLGLGDPNTISWGIMLYNVQTSSSMLIGAWWELLAPCLSLTLLVTGLALLNFAVDE
HHHHHHCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IANPQLRSHKGMKRWKNLAKQDQKAREPNVPPQNALWSGDK
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKALWKLLRGNRMAMIGVTILGLFFLLAVAAPLLTSHEPDKRTGNPHEYPAFVVKAAKAN
CHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEECCCC
PDGWIAENLATDRRTLAMSKKADHILGTTRMGRDVWSQVAYGARVSLAVGFGAGITVCFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHH
ATVIGVSAGYFGGKIDDFLTAAMNIMLVIPQYPLLFVLAAFIGEAGPLTIALIIGCTSWA
HHHHHHHCCCCCCHHHHHHHHHHHHHEECCCHHHHHHHHHHHCCCCCCEEEEEEECCCHH
WGARVVRSQTMALREKEFVKAAEVLGESSWRIIFIEILPNLISIVGASFIGSVMYAIMME
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
ATISFLGLGDPNTISWGIMLYNVQTSSSMLIGAWWELLAPCLSLTLLVTGLALLNFAVDE
HHHHHHCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IANPQLRSHKGMKRWKNLAKQDQKAREPNVPPQNALWSGDK
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]