Click here to switch to the map view.

The map label for this gene is mcp4 [H]

Identifier: 227080659

GI number: 227080659

Start: 464049

End: 465674

Strand: Reverse

Name: mcp4 [H]

Synonym: VCM66_0434

Alternate gene names: 227080659

Gene position: 465674-464049 (Counterclockwise)

Preceding gene: 227080660

Following gene: 227080657

Centisome position: 16.1

GC content: 50.37

Gene sequence:

>1626_bases
ATGAAATTAAAAACCCAAGCTTATTTATTATCTGCCATCATTCTCGCCGCTCTTCTCGCGCTAACCGCGACCGGACTGTG
GACGTTACGTGTGGCCAGCAATCTCGATAACAAAGCGCGTGTAACCGAGCTGTTTAATAGTGCCTACAGTATTTTGACTG
AGGTAGAGAAGCTGGCTCAAGAAGGCAAGATGTCGGAGCCAGAAGCCAAAGCGCTCGCCACCCGCCTAATGCGCAACAAT
CTCTACAAAGATAATGAATATGTGTATGTGGCAGATGAAAATATGACTTTCGTGGCGACGCCGCTCGACCCACAACTGCA
CGACACCAGTTTTCACGATTTTAAAGATGGTAAAGGCAATAGTGTTGGCCGCTTAATTCAAGATGTGCTGCGTCATCAAT
CCGGCAAGTTGGTGGAATATACGTGGACACAAAAGCAAGCTGACGGTTCGATTGAAGAAAAGCTCTCGATCGCGCGCAAA
ACGCCACACTGGGGCTGGGTTGTCGGCACGGGTATTGGTTTTAACGAAGTGAATGCGCGTTTTTGGTCTACCGCGCAATG
GCAACTAAGCTTATGTGTGGTGATCGCCGTTGCGATTTTATCTCTGCTACTGGTCGCGATTCGTAAAATACTGCTGATTA
TCGGCGGTGAACCCAATGAGGTACGCAGCGCAGTACAAGCGGTGGCACAAGGCCGCATTCGTCGTGAATTTGTGATAAAA
GCCCCTAAAGAGAGTATTTATGGTGCAGTGCAGCAGATGAGCAGCTCACTTGCAGACTTGGTGGCTAAGCTTGAGCAATC
CATGGTGGCTTTACGCTCTGAATTAGCCGGCGCAGGTACTCGCGCCAAAAGCATTGCCGAATTAACGGATAGCCAGCAGC
AATCTACCGCCATGATTGCCACTGCAATGACCGAAATGGCCTCTTCAGCGAACCAAGTCGCCGATTCTGCGCGTGATACC
GCATTCAACACCGATCAAGCGGATCAGCAAAGCCAGCATACGCAAAAGCTCATCCACAACACGGTAAGCAATATTCAAGG
CTTGGCGACCCAATTACAAACTGCGAGCACCGCGGTTGCCGATCTGGATCTGGATGTCAAAAACATCGCTAAAGTACTGG
ATGTGATTGGTGATATTGCAGAGCAAACCAATTTACTGGCGCTGAATGCCGCGATTGAAGCAGCACGCGCTGGCGAGCAA
GGGCGCGGTTTTGCCGTCGTGGCTGATGAAGTGCGTAACTTAGCGGGCCGCACGCAAACCAGTACCAAAGAGATCCAGCA
GATGATCCACAATTTGCAGGAAGGGTCGCGTAATGCGATTCAAACCATCCAGATTTGTGGGCAAACCAGTCAAAGCAGTG
TGCAAGAGTCAGAAAATGCCGCTTCTGCGCTGGCATTGATTGTCAGCGCACTCGAAAGCGTCTCTTCGATGAGCCATCAA
ATAGCCACGGCGGCCGCTGAGCAAACCCAAGTCAGCGATGATATTGCGCGCCGAATCAATATGATTGAAGAAAGTGGCTC
AAAACTGAGCCGAGTGGTGATGGAGAGCCACAATAGTACGCAAACTCTCACCAAACTCGCCCGCGAGTTAGAACAGTGGG
CTGCGCATTTTGAGGTCACTCGTTAA

Upstream 100 bases:

>100_bases
TACTTCGTATCAATAAATAAGCAAGCTCATTACTATCTCGCCGACATCAAACCGTCACAAAAATTTAATCTGCTTACACC
TTCCCCATAGGGTTCAAACT

Downstream 100 bases:

>100_bases
GCATACTTTCAGTTCAGTGAGCGCAAAACGTTTCACTGAACTGATGGGTTACCCGTCGTTATGATACCCAAACTTCTTGA
CGTTGCCTGTCGTCAGCCAG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MKLKTQAYLLSAIILAALLALTATGLWTLRVASNLDNKARVTELFNSAYSILTEVEKLAQEGKMSEPEAKALATRLMRNN
LYKDNEYVYVADENMTFVATPLDPQLHDTSFHDFKDGKGNSVGRLIQDVLRHQSGKLVEYTWTQKQADGSIEEKLSIARK
TPHWGWVVGTGIGFNEVNARFWSTAQWQLSLCVVIAVAILSLLLVAIRKILLIIGGEPNEVRSAVQAVAQGRIRREFVIK
APKESIYGAVQQMSSSLADLVAKLEQSMVALRSELAGAGTRAKSIAELTDSQQQSTAMIATAMTEMASSANQVADSARDT
AFNTDQADQQSQHTQKLIHNTVSNIQGLATQLQTASTAVADLDLDVKNIAKVLDVIGDIAEQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRNLAGRTQTSTKEIQQMIHNLQEGSRNAIQTIQICGQTSQSSVQESENAASALALIVSALESVSSMSHQ
IATAAAEQTQVSDDIARRINMIEESGSKLSRVVMESHNSTQTLTKLARELEQWAAHFEVTR

Sequences:

>Translated_541_residues
MKLKTQAYLLSAIILAALLALTATGLWTLRVASNLDNKARVTELFNSAYSILTEVEKLAQEGKMSEPEAKALATRLMRNN
LYKDNEYVYVADENMTFVATPLDPQLHDTSFHDFKDGKGNSVGRLIQDVLRHQSGKLVEYTWTQKQADGSIEEKLSIARK
TPHWGWVVGTGIGFNEVNARFWSTAQWQLSLCVVIAVAILSLLLVAIRKILLIIGGEPNEVRSAVQAVAQGRIRREFVIK
APKESIYGAVQQMSSSLADLVAKLEQSMVALRSELAGAGTRAKSIAELTDSQQQSTAMIATAMTEMASSANQVADSARDT
AFNTDQADQQSQHTQKLIHNTVSNIQGLATQLQTASTAVADLDLDVKNIAKVLDVIGDIAEQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRNLAGRTQTSTKEIQQMIHNLQEGSRNAIQTIQICGQTSQSSVQESENAASALALIVSALESVSSMSHQ
IATAAAEQTQVSDDIARRINMIEESGSKLSRVVMESHNSTQTLTKLARELEQWAAHFEVTR
>Mature_541_residues
MKLKTQAYLLSAIILAALLALTATGLWTLRVASNLDNKARVTELFNSAYSILTEVEKLAQEGKMSEPEAKALATRLMRNN
LYKDNEYVYVADENMTFVATPLDPQLHDTSFHDFKDGKGNSVGRLIQDVLRHQSGKLVEYTWTQKQADGSIEEKLSIARK
TPHWGWVVGTGIGFNEVNARFWSTAQWQLSLCVVIAVAILSLLLVAIRKILLIIGGEPNEVRSAVQAVAQGRIRREFVIK
APKESIYGAVQQMSSSLADLVAKLEQSMVALRSELAGAGTRAKSIAELTDSQQQSTAMIATAMTEMASSANQVADSARDT
AFNTDQADQQSQHTQKLIHNTVSNIQGLATQLQTASTAVADLDLDVKNIAKVLDVIGDIAEQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRNLAGRTQTSTKEIQQMIHNLQEGSRNAIQTIQICGQTSQSSVQESENAASALALIVSALESVSSMSHQ
IATAAAEQTQVSDDIARRINMIEESGSKLSRVVMESHNSTQTLTKLARELEQWAAHFEVTR

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=327, Percent_Identity=33.0275229357798, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788194, Length=366, Percent_Identity=27.5956284153005, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI2367378, Length=407, Percent_Identity=27.027027027027, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1787690, Length=238, Percent_Identity=31.5126050420168, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789453, Length=243, Percent_Identity=30.0411522633745, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58815; Mature: 58815

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKTQAYLLSAIILAALLALTATGLWTLRVASNLDNKARVTELFNSAYSILTEVEKLAQ
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
EGKMSEPEAKALATRLMRNNLYKDNEYVYVADENMTFVATPLDPQLHDTSFHDFKDGKGN
CCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCC
SVGRLIQDVLRHQSGKLVEYTWTQKQADGSIEEKLSIARKTPHWGWVVGTGIGFNEVNAR
CHHHHHHHHHHCCCCCEEEEEECCHHCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHCHH
FWSTAQWQLSLCVVIAVAILSLLLVAIRKILLIIGGEPNEVRSAVQAVAQGRIRREFVIK
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
APKESIYGAVQQMSSSLADLVAKLEQSMVALRSELAGAGTRAKSIAELTDSQQQSTAMIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHH
TAMTEMASSANQVADSARDTAFNTDQADQQSQHTQKLIHNTVSNIQGLATQLQTASTAVA
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLDLDVKNIAKVLDVIGDIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAGRTQT
HCCCCHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCC
STKEIQQMIHNLQEGSRNAIQTIQICGQTSQSSVQESENAASALALIVSALESVSSMSHQ
CHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IATAAAEQTQVSDDIARRINMIEESGSKLSRVVMESHNSTQTLTKLARELEQWAAHFEVT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
R
C
>Mature Secondary Structure
MKLKTQAYLLSAIILAALLALTATGLWTLRVASNLDNKARVTELFNSAYSILTEVEKLAQ
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
EGKMSEPEAKALATRLMRNNLYKDNEYVYVADENMTFVATPLDPQLHDTSFHDFKDGKGN
CCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCC
SVGRLIQDVLRHQSGKLVEYTWTQKQADGSIEEKLSIARKTPHWGWVVGTGIGFNEVNAR
CHHHHHHHHHHCCCCCEEEEEECCHHCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHCHH
FWSTAQWQLSLCVVIAVAILSLLLVAIRKILLIIGGEPNEVRSAVQAVAQGRIRREFVIK
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
APKESIYGAVQQMSSSLADLVAKLEQSMVALRSELAGAGTRAKSIAELTDSQQQSTAMIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHH
TAMTEMASSANQVADSARDTAFNTDQADQQSQHTQKLIHNTVSNIQGLATQLQTASTAVA
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLDLDVKNIAKVLDVIGDIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAGRTQT
HCCCCHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCC
STKEIQQMIHNLQEGSRNAIQTIQICGQTSQSSVQESENAASALALIVSALESVSSMSHQ
CHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IATAAAEQTQVSDDIARRINMIEESGSKLSRVVMESHNSTQTLTKLARELEQWAAHFEVT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]