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The map label for this gene is surA

Identifier: 227080656

GI number: 227080656

Start: 458254

End: 459549

Strand: Reverse

Name: surA

Synonym: VCM66_0430

Alternate gene names: 227080656

Gene position: 459549-458254 (Counterclockwise)

Preceding gene: 227080657

Following gene: 227080655

Centisome position: 15.89

GC content: 48.23

Gene sequence:

>1296_bases
ATGAAATTGTGGAAACCCACACTAATTAGCGTTCTCAGTGCGCTGACTCTCTTCAACGCTCACGCAGAGCCCAAACAACT
CGATAGCGTGGCAGTGATTGTCAATAGCGGCGTCATACTACAAAGTGATGTGGACAGCGCCCTGAAAACCATCAAAGCCA
ATGCCAAGCAGAACAAGCAGCCTTTGCCACAAGAAACGGTGCTGCGCGAACAAGTATTGGAAAAACTGATCATCGATACT
TTGCAGCAGCAAGAAGCGGATCGGATTGGGGTAAAAATTGATGACAACCGCCTCAACGAAGCGATTAAAGAGATAGCGAA
AAACAACCAACAGACTCAGGAGCAGTTGATTGCTTCGGTAGCGCAAGAAGGCTTAACTTACCCAGAGTTCCGTGAGCAAG
TCCGTAAAGAGATGGCGGCGAGTGATGCACGCAATGCCTTAGTTCGTCGTCGTATCAACATTCTGCCCGCCGAAGTTGAT
ACGTTAGCTGAGCTGCTGGCGCAGGAAACCGATGCCACCGTGCAATACAAAATCAGTCATATTCAACTGCGAGTCGATGA
CGGACAAGATAAAAGTACCGCGGAAACCTTGGCCAACAAGCTGGTCAACGACCTAAGAAATGGGGCAGACTTTGCGCAAA
TGGCGTACGCCTACTCCAAAGGTCCCAAAGCCCTGCAAGGGGGAGATTGGGGATGGATGCGCAAAGAAGAGATGCCAACC
ATCTTTGCTGATCAGATCAAAATGCAGAACAAAGGCAGCATTATTGGCCCGTTTCGCAGTGGTGTCGGTTTTCACATTTT
GAAAATAGATGATGTCAAAGGCCTAGAAACGGTCGCGGTCACAGAAGTTAATGCTCGTCACATTTTGATCAAACCGACCA
TCATCCTCAGCGATGAAGGCGCGCAAAAGCAGCTCAATGAATTTGTACAGCGCATCAAAAATGGCGAAGTGACCTTTGCA
GAATTAGCACAGCAATATAGCCAAGACCCCGGCTCTGCCGCGCAAAAAGGTGAACTGGGCTATCAAACTCCTGATCTGTA
TGTCCCAGAGTTTAAACACCAGATTGAAACCTTACCCGTAGGCCAAATCAGTGAACCGTTTAAAACCGTACATGGTTGGC
ACATTGTAGAAGTGCTCGATCGTCGCGAAGTGGACAGAACTGATTCCGCACTGAAAAACAAGGCCTACCGTATCTTGTTC
AATCGTAAATTCAATGAAGAAGCCAGTGCTTGGCTGCAAGAGCTGCGTGCCAGCGCCTTTGTTGAAGTATTGAAGGACGA
GAAGGATGAGCAGTAA

Upstream 100 bases:

>100_bases
GCAGGTAACTCACTCGGTTATGGTCGCCCATTCTTCCTGAATAACTAATTCACCTAGCCTGAGGAAACTCAGGCTTAAAA
CATTTTAGATAGGACTGTAC

Downstream 100 bases:

>100_bases
ACGCATCATTGTCACAGCCGGTGAGCCCGCGGGGATCGGTCCCGATCTGGTGCTCGCCCTCTCCGCGCAAGATTGGCCAC
ATCAACTGGTGGTGTGTGCC

Product: survival protein SurA

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MKLWKPTLISVLSALTLFNAHAEPKQLDSVAVIVNSGVILQSDVDSALKTIKANAKQNKQPLPQETVLREQVLEKLIIDT
LQQQEADRIGVKIDDNRLNEAIKEIAKNNQQTQEQLIASVAQEGLTYPEFREQVRKEMAASDARNALVRRRINILPAEVD
TLAELLAQETDATVQYKISHIQLRVDDGQDKSTAETLANKLVNDLRNGADFAQMAYAYSKGPKALQGGDWGWMRKEEMPT
IFADQIKMQNKGSIIGPFRSGVGFHILKIDDVKGLETVAVTEVNARHILIKPTIILSDEGAQKQLNEFVQRIKNGEVTFA
ELAQQYSQDPGSAAQKGELGYQTPDLYVPEFKHQIETLPVGQISEPFKTVHGWHIVEVLDRREVDRTDSALKNKAYRILF
NRKFNEEASAWLQELRASAFVEVLKDEKDEQ

Sequences:

>Translated_431_residues
MKLWKPTLISVLSALTLFNAHAEPKQLDSVAVIVNSGVILQSDVDSALKTIKANAKQNKQPLPQETVLREQVLEKLIIDT
LQQQEADRIGVKIDDNRLNEAIKEIAKNNQQTQEQLIASVAQEGLTYPEFREQVRKEMAASDARNALVRRRINILPAEVD
TLAELLAQETDATVQYKISHIQLRVDDGQDKSTAETLANKLVNDLRNGADFAQMAYAYSKGPKALQGGDWGWMRKEEMPT
IFADQIKMQNKGSIIGPFRSGVGFHILKIDDVKGLETVAVTEVNARHILIKPTIILSDEGAQKQLNEFVQRIKNGEVTFA
ELAQQYSQDPGSAAQKGELGYQTPDLYVPEFKHQIETLPVGQISEPFKTVHGWHIVEVLDRREVDRTDSALKNKAYRILF
NRKFNEEASAWLQELRASAFVEVLKDEKDEQ
>Mature_431_residues
MKLWKPTLISVLSALTLFNAHAEPKQLDSVAVIVNSGVILQSDVDSALKTIKANAKQNKQPLPQETVLREQVLEKLIIDT
LQQQEADRIGVKIDDNRLNEAIKEIAKNNQQTQEQLIASVAQEGLTYPEFREQVRKEMAASDARNALVRRRINILPAEVD
TLAELLAQETDATVQYKISHIQLRVDDGQDKSTAETLANKLVNDLRNGADFAQMAYAYSKGPKALQGGDWGWMRKEEMPT
IFADQIKMQNKGSIIGPFRSGVGFHILKIDDVKGLETVAVTEVNARHILIKPTIILSDEGAQKQLNEFVQRIKNGEVTFA
ELAQQYSQDPGSAAQKGELGYQTPDLYVPEFKHQIETLPVGQISEPFKTVHGWHIVEVLDRREVDRTDSALKNKAYRILF
NRKFNEEASAWLQELRASAFVEVLKDEKDEQ

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains

Homologues:

Organism=Escherichia coli, GI1786238, Length=430, Percent_Identity=46.046511627907, Blast_Score=392, Evalue=1e-110,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): SURA_VIBCH (Q9KUS0)

Other databases:

- EMBL:   AE003852
- PIR:   D82323
- RefSeq:   NP_230099.1
- HSSP:   Q9Y237
- ProteinModelPortal:   Q9KUS0
- SMR:   Q9KUS0
- GeneID:   2615777
- GenomeReviews:   AE003852_GR
- KEGG:   vch:VC0445
- TIGR:   VC_0445
- HOGENOM:   HBG391483
- OMA:   NDRVITN
- ProtClustDB:   CLSK873981
- BRENDA:   5.2.1.8
- HAMAP:   MF_01183
- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N; SSF109998 Trigger_fac_C_bac

EC number: =5.2.1.8

Molecular weight: Translated: 48489; Mature: 48489

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS01096 PPIC_PPIASE_1; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLWKPTLISVLSALTLFNAHAEPKQLDSVAVIVNSGVILQSDVDSALKTIKANAKQNKQ
CCCCHHHHHHHHHHHHHHHCCCCCHHHCCEEEEEECCEEEECHHHHHHHHHHHHHHCCCC
PLPQETVLREQVLEKLIIDTLQQQEADRIGVKIDDNRLNEAIKEIAKNNQQTQEQLIASV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHCCHHHHHHHHHHH
AQEGLTYPEFREQVRKEMAASDARNALVRRRINILPAEVDTLAELLAQETDATVQYKISH
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEEE
IQLRVDDGQDKSTAETLANKLVNDLRNGADFAQMAYAYSKGPKALQGGDWGWMRKEEMPT
EEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCH
IFADQIKMQNKGSIIGPFRSGVGFHILKIDDVKGLETVAVTEVNARHILIKPTIILSDEG
HHHHHHHCCCCCCEECCHHCCCCEEEEEECCCCCCCEEEEEECCCCEEEEEEEEEECCCC
AQKQLNEFVQRIKNGEVTFAELAQQYSQDPGSAAQKGELGYQTPDLYVPEFKHQIETLPV
HHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHCCCC
GQISEPFKTVHGWHIVEVLDRREVDRTDSALKNKAYRILFNRKFNEEASAWLQELRASAF
CCCCHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHH
VEVLKDEKDEQ
HHHHHHCCCCC
>Mature Secondary Structure
MKLWKPTLISVLSALTLFNAHAEPKQLDSVAVIVNSGVILQSDVDSALKTIKANAKQNKQ
CCCCHHHHHHHHHHHHHHHCCCCCHHHCCEEEEEECCEEEECHHHHHHHHHHHHHHCCCC
PLPQETVLREQVLEKLIIDTLQQQEADRIGVKIDDNRLNEAIKEIAKNNQQTQEQLIASV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHCCHHHHHHHHHHH
AQEGLTYPEFREQVRKEMAASDARNALVRRRINILPAEVDTLAELLAQETDATVQYKISH
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEEE
IQLRVDDGQDKSTAETLANKLVNDLRNGADFAQMAYAYSKGPKALQGGDWGWMRKEEMPT
EEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCH
IFADQIKMQNKGSIIGPFRSGVGFHILKIDDVKGLETVAVTEVNARHILIKPTIILSDEG
HHHHHHHCCCCCCEECCHHCCCCEEEEEECCCCCCCEEEEEECCCCEEEEEEEEEECCCC
AQKQLNEFVQRIKNGEVTFAELAQQYSQDPGSAAQKGELGYQTPDLYVPEFKHQIETLPV
HHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHCCCC
GQISEPFKTVHGWHIVEVLDRREVDRTDSALKNKAYRILFNRKFNEEASAWLQELRASAF
CCCCHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHH
VEVLKDEKDEQ
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301