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The map label for this gene is apaH

Identifier: 227080652

GI number: 227080652

Start: 455171

End: 455980

Strand: Reverse

Name: apaH

Synonym: VCM66_0426

Alternate gene names: 227080652

Gene position: 455980-455171 (Counterclockwise)

Preceding gene: 227080653

Following gene: 227080645

Centisome position: 15.76

GC content: 50.86

Gene sequence:

>810_bases
GTGGCGAATTATATCGTTGGAGATATTCAAGGCTGCTTTGACGAGCTACAGCAACTGCTCAAGCAGGCCGAATTTAATTC
TCAGCTTGATACGCTGTGGTTTGCGGGAGATTTGGTCGCTCGTGGTCCAAAATCACTAGAAACCTTGCGTTTTGTCTATC
AGTTAGGGGATGCAGCACGAGTCGTGCTCGGCAATCATGATTTGCATTTGCTCTCAGTAGCACTCGGTCACCACTCCGCT
AAACGGCGCGATCAAACCCAAGCGGTTTTAGATGCGCCTGACGCCGCGCCATTACTCGATTGGCTACGTCAGCAGCCTTT
GCTCGCTGAACATCAAGAGTTTGTACTGTGCCATGCTGGCATCTCACCACAATGGGATCTCGCCACTGCACGCCAAGCTG
CGCAAGAGGTCGAGTCTGTACTTCGCAGCCCCGAGTGGAGCACCCTGATTGAGCAGATGTACAGTGACCAACCCGACGCA
TGGCATCCAACGCTACAAGGGATAGATCGCTTGCGTTATATCGTTAACGCATTTACTCGTATGCGCTTTTGTTTCCCAGA
TGGTCGTTTAGATATGCAATGCAAACTGCCACCGAAAGAAGTGACTGACGGTAGCTTACTACCTTGGTTCCAATTACCGC
AGCGTATTGCTCTTGAAAAGACGGTGATTTTTGGCCATTGGGCGGCATTAGAAGGGTATGTGAGTGAAACGGTGATCGGC
CTAGATACGGGTTGTGTGTGGGGCGGAACCCTGACTATGCTGCGTTGGGAAGATAAACACTACTTTAGCCAAGCAGCGCT
GCCAGCATAA

Upstream 100 bases:

>100_bases
GGGCAATATTTGATGATCGATGAACAAGGTGAGTCTTTCACGGTTGAGATTGAACCATTTCGTTTAGCCGTTCCGCATGT
ATTGAATTAAGGGAGTTTGT

Downstream 100 bases:

>100_bases
AACAACACCCGTTAATACGGGTGTTGAGTGTATTTTCTCTGACGATACCTGCAATGACGATCCCCAAACGACTTGGAGTT
GCAGGTAGGCGGCAAAATAA

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MANYIVGDIQGCFDELQQLLKQAEFNSQLDTLWFAGDLVARGPKSLETLRFVYQLGDAARVVLGNHDLHLLSVALGHHSA
KRRDQTQAVLDAPDAAPLLDWLRQQPLLAEHQEFVLCHAGISPQWDLATARQAAQEVESVLRSPEWSTLIEQMYSDQPDA
WHPTLQGIDRLRYIVNAFTRMRFCFPDGRLDMQCKLPPKEVTDGSLLPWFQLPQRIALEKTVIFGHWAALEGYVSETVIG
LDTGCVWGGTLTMLRWEDKHYFSQAALPA

Sequences:

>Translated_269_residues
MANYIVGDIQGCFDELQQLLKQAEFNSQLDTLWFAGDLVARGPKSLETLRFVYQLGDAARVVLGNHDLHLLSVALGHHSA
KRRDQTQAVLDAPDAAPLLDWLRQQPLLAEHQEFVLCHAGISPQWDLATARQAAQEVESVLRSPEWSTLIEQMYSDQPDA
WHPTLQGIDRLRYIVNAFTRMRFCFPDGRLDMQCKLPPKEVTDGSLLPWFQLPQRIALEKTVIFGHWAALEGYVSETVIG
LDTGCVWGGTLTMLRWEDKHYFSQAALPA
>Mature_268_residues
ANYIVGDIQGCFDELQQLLKQAEFNSQLDTLWFAGDLVARGPKSLETLRFVYQLGDAARVVLGNHDLHLLSVALGHHSAK
RRDQTQAVLDAPDAAPLLDWLRQQPLLAEHQEFVLCHAGISPQWDLATARQAAQEVESVLRSPEWSTLIEQMYSDQPDAW
HPTLQGIDRLRYIVNAFTRMRFCFPDGRLDMQCKLPPKEVTDGSLLPWFQLPQRIALEKTVIFGHWAALEGYVSETVIGL
DTGCVWGGTLTMLRWEDKHYFSQAALPA

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family

Homologues:

Organism=Escherichia coli, GI1786234, Length=269, Percent_Identity=55.0185873605948, Blast_Score=308, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): APAH_VIBC3 (A5F8N0)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F8N0
- SMR:   A5F8N0
- STRING:   A5F8N0
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A2859
- eggNOG:   COG0639
- HOGENOM:   HBG724457
- OMA:   LVFGHWA
- ProtClustDB:   PRK00166
- BioCyc:   VCHO345073:VC0395_A2859-MONOMER
- HAMAP:   MF_00199
- InterPro:   IPR004617
- InterPro:   IPR004843
- PIRSF:   PIRSF000903
- TIGRFAMs:   TIGR00668

Pfam domain/function: PF00149 Metallophos

EC number: =3.6.1.41

Molecular weight: Translated: 30408; Mature: 30277

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANYIVGDIQGCFDELQQLLKQAEFNSQLDTLWFAGDLVARGPKSLETLRFVYQLGDAAR
CCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEE
VVLGNHDLHLLSVALGHHSAKRRDQTQAVLDAPDAAPLLDWLRQQPLLAEHQEFVLCHAG
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHCCCCEEEEECC
ISPQWDLATARQAAQEVESVLRSPEWSTLIEQMYSDQPDAWHPTLQGIDRLRYIVNAFTR
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
MRFCFPDGRLDMQCKLPPKEVTDGSLLPWFQLPQRIALEKTVIFGHWAALEGYVSETVIG
HHEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
LDTGCVWGGTLTMLRWEDKHYFSQAALPA
CCCCCCCCCEEEEEEECCHHHHHHCCCCC
>Mature Secondary Structure 
ANYIVGDIQGCFDELQQLLKQAEFNSQLDTLWFAGDLVARGPKSLETLRFVYQLGDAAR
CCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEE
VVLGNHDLHLLSVALGHHSAKRRDQTQAVLDAPDAAPLLDWLRQQPLLAEHQEFVLCHAG
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHCCCCEEEEECC
ISPQWDLATARQAAQEVESVLRSPEWSTLIEQMYSDQPDAWHPTLQGIDRLRYIVNAFTR
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
MRFCFPDGRLDMQCKLPPKEVTDGSLLPWFQLPQRIALEKTVIFGHWAALEGYVSETVIG
HHEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
LDTGCVWGGTLTMLRWEDKHYFSQAALPA
CCCCCCCCCEEEEEEECCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA