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The map label for this gene is foxA [H]

Identifier: 227080498

GI number: 227080498

Start: 276682

End: 278724

Strand: Reverse

Name: foxA [H]

Synonym: VCM66_0269

Alternate gene names: 227080498

Gene position: 278724-276682 (Counterclockwise)

Preceding gene: 227080499

Following gene: 227080497

Centisome position: 9.64

GC content: 53.06

Gene sequence:

>2043_bases
ATGTCTCATTTTACTCGCTCAAGAACCTGGGTCAGTCTGGCCGTTTTCGCCGCTTGTGCCCCCGCCCATGCCGAACAAGA
AACCTTGGTCATCACCAGTCAACAAAGCCAACTGCCGGAAGTCGCCACTGCAACCCGCACCGCCACTCCGGCGAAACTGG
TGCCGCAAACCATTGATTCACTTTCAGCGGAAGAGCTGACCGCGTTTGGCGCGCCCAGCCTAAGCGAAGCTTTAGCTGGG
GTACCGGGGGTCAACGCCAACGGCGATACCCGTTTTGACGGCATCAATATTCGTGGATTTTCCGCCAGCAACGATTTTTA
TCTCGATGGTTTTCGTGATGATATGCAGTACACCCGCGATCTCGGCAACATCGAGCGTATCGAAGTTCTCAAAGGCCCTG
CGGCGGTGTTGTATGGCCGTGGTAGTACAGGGGGTATCGTCAACCGCGTCAGCAAAGTGCCACACGCAGGTGATGCCGCG
AGCGTTTCTGCACGCATTGGCAGCCATGATTACCAACGCCTTGCCGCCGATCTCAATGGTGAGGTCAATCAGCAAGTGCA
AGTTCGCCTGAATATCGCTCAAGAAGATTACGGCAGTTTCCGCCATGGCGTGGAAGGCAAACGCACTTTGCTTGCTCCGT
CTCTGAACTGGGACATCAATGATGATGTGAGCTGGCTTATCCAGTATGAGCAACACTCCCATAATCGCGTGCCAGATCGT
GGTATTCCGGCGGTGAATGGCTCTCCTGCTGAGGTTCCTGCGAGCAGTGTTTACAGCGATACCAGCCGTGACTTTATTGA
TGATGATGTGGCCACCACGCGCTCACGCATTACTTGGGCATTCCACCCAGAATGGCAACTGCGCCAACAACTGAGCTACA
CCAAGCTCGATAGTCAGTTTGATAACACTTACGTAGCTCGCGTCAGTGGCGACCAAGTCACGCGTCAACGCTTCCAACAA
GATCTGCAAGCCAACAACCTGATCAGCAATACCGAAACAGAAGGCACCTTCAATACGGGCCCGATTGCTCACCGAATTCT
GATCGGTCTAGAGCAGGGCTGGCAAGAGCGCTCGCCGAAACTGTATCGCAACGCCAACAGCATCCCGAGTGGCAACCTGT
ACCAACCTGAGTCACTGCCGACCTACAACGGACCTATGTCAGTATTTAGTGATGCCACTCATAAAGTGCGGAGCTACGGT
ATTTATGTCCAAGATCAACTGCAATGGGGAGATTGGATTGTGTTGGCAGGTCTGCGTCACGATGATTTCACCGTCACGAC
TCATCGCCACGATACCCATAAAGAAGAGACCATCTCATCCAACAGCTTAAGCCCACGTTTAGGTGTGGTATGGACCCCTG
TGCAAGAGCATGCGTTGTACGCTTCCTACTCACAAACCTATTCTCCGGTTGGTGGTGGCGTTATTGGCATTACGCCGGGA
GACAAACATAACCACCTCGATCCTGAGCACTCACGCCTGTATGAAACTGGCGTCAAAAGCGATTGGCTAGAGGGACGCAT
CTCAACCACTTTATCCGTCTATCGCTTAGAAATGTATAACCGCCGTATGCGTGATCCGAATGATCAGGAGCGTATTATTC
TCACCGGATTACAACGTACCGATGGTATTGAGCTGAGCAGCCGTGCACTTCTCACCGATGAATTTTCTCTGCGTGGCGGC
ATTGGCCTGCAAGATGCAAAATACGTCGAAGCTGATGCCAGTGAGCAAGGTAAACGCCCAACCAACGTATCGCGCCTCAA
TGGTGAGCTGTTTGTCGCTTATCAATCGGCAAGCGATGGCTGGTTTGGTGAGACCGGTTTTGTGGCGGTCGGCGATCGCT
ATGCCGATCGTACTAACACCACCAAACTGCCCGGTTATGCCCGTTTCGATGCACGTCTCGGCTACCAATGGCAAGCTTGG
CGCACTCAACTGAGCGTAGAAAACCTGCTCGATAAGGATTACTACCTGAGTGCCACCAGCAGCACACAAATTCAGCCGGG
TGCACCGCGTGAGTTCTACCTCACAGCGTCTTACCAGTTCTAA

Upstream 100 bases:

>100_bases
CTTGAATCAATAATGAAAATTACTATCATTTGCGATTCATTTTTGTGGCGAATGTTTGCCACTGACATTATTCGTCAATA
ATAAATAGAGTTAATCCTTC

Downstream 100 bases:

>100_bases
ACGATTGATCCCCATTTGGCATGCAGCGGCAAGTCAAAGGGGATAACCACAGGAGAGCTGGCCTAACGGCCAGCTTGATT
ATGCAACGTCGACGCCTGCC

Product: TonB system receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 680; Mature: 679

Protein sequence:

>680_residues
MSHFTRSRTWVSLAVFAACAPAHAEQETLVITSQQSQLPEVATATRTATPAKLVPQTIDSLSAEELTAFGAPSLSEALAG
VPGVNANGDTRFDGINIRGFSASNDFYLDGFRDDMQYTRDLGNIERIEVLKGPAAVLYGRGSTGGIVNRVSKVPHAGDAA
SVSARIGSHDYQRLAADLNGEVNQQVQVRLNIAQEDYGSFRHGVEGKRTLLAPSLNWDINDDVSWLIQYEQHSHNRVPDR
GIPAVNGSPAEVPASSVYSDTSRDFIDDDVATTRSRITWAFHPEWQLRQQLSYTKLDSQFDNTYVARVSGDQVTRQRFQQ
DLQANNLISNTETEGTFNTGPIAHRILIGLEQGWQERSPKLYRNANSIPSGNLYQPESLPTYNGPMSVFSDATHKVRSYG
IYVQDQLQWGDWIVLAGLRHDDFTVTTHRHDTHKEETISSNSLSPRLGVVWTPVQEHALYASYSQTYSPVGGGVIGITPG
DKHNHLDPEHSRLYETGVKSDWLEGRISTTLSVYRLEMYNRRMRDPNDQERIILTGLQRTDGIELSSRALLTDEFSLRGG
IGLQDAKYVEADASEQGKRPTNVSRLNGELFVAYQSASDGWFGETGFVAVGDRYADRTNTTKLPGYARFDARLGYQWQAW
RTQLSVENLLDKDYYLSATSSTQIQPGAPREFYLTASYQF

Sequences:

>Translated_680_residues
MSHFTRSRTWVSLAVFAACAPAHAEQETLVITSQQSQLPEVATATRTATPAKLVPQTIDSLSAEELTAFGAPSLSEALAG
VPGVNANGDTRFDGINIRGFSASNDFYLDGFRDDMQYTRDLGNIERIEVLKGPAAVLYGRGSTGGIVNRVSKVPHAGDAA
SVSARIGSHDYQRLAADLNGEVNQQVQVRLNIAQEDYGSFRHGVEGKRTLLAPSLNWDINDDVSWLIQYEQHSHNRVPDR
GIPAVNGSPAEVPASSVYSDTSRDFIDDDVATTRSRITWAFHPEWQLRQQLSYTKLDSQFDNTYVARVSGDQVTRQRFQQ
DLQANNLISNTETEGTFNTGPIAHRILIGLEQGWQERSPKLYRNANSIPSGNLYQPESLPTYNGPMSVFSDATHKVRSYG
IYVQDQLQWGDWIVLAGLRHDDFTVTTHRHDTHKEETISSNSLSPRLGVVWTPVQEHALYASYSQTYSPVGGGVIGITPG
DKHNHLDPEHSRLYETGVKSDWLEGRISTTLSVYRLEMYNRRMRDPNDQERIILTGLQRTDGIELSSRALLTDEFSLRGG
IGLQDAKYVEADASEQGKRPTNVSRLNGELFVAYQSASDGWFGETGFVAVGDRYADRTNTTKLPGYARFDARLGYQWQAW
RTQLSVENLLDKDYYLSATSSTQIQPGAPREFYLTASYQF
>Mature_679_residues
SHFTRSRTWVSLAVFAACAPAHAEQETLVITSQQSQLPEVATATRTATPAKLVPQTIDSLSAEELTAFGAPSLSEALAGV
PGVNANGDTRFDGINIRGFSASNDFYLDGFRDDMQYTRDLGNIERIEVLKGPAAVLYGRGSTGGIVNRVSKVPHAGDAAS
VSARIGSHDYQRLAADLNGEVNQQVQVRLNIAQEDYGSFRHGVEGKRTLLAPSLNWDINDDVSWLIQYEQHSHNRVPDRG
IPAVNGSPAEVPASSVYSDTSRDFIDDDVATTRSRITWAFHPEWQLRQQLSYTKLDSQFDNTYVARVSGDQVTRQRFQQD
LQANNLISNTETEGTFNTGPIAHRILIGLEQGWQERSPKLYRNANSIPSGNLYQPESLPTYNGPMSVFSDATHKVRSYGI
YVQDQLQWGDWIVLAGLRHDDFTVTTHRHDTHKEETISSNSLSPRLGVVWTPVQEHALYASYSQTYSPVGGGVIGITPGD
KHNHLDPEHSRLYETGVKSDWLEGRISTTLSVYRLEMYNRRMRDPNDQERIILTGLQRTDGIELSSRALLTDEFSLRGGI
GLQDAKYVEADASEQGKRPTNVSRLNGELFVAYQSASDGWFGETGFVAVGDRYADRTNTTKLPGYARFDARLGYQWQAWR
TQLSVENLLDKDYYLSATSSTQIQPGAPREFYLTASYQF

Specific function: Ferrioxamine binding and uptake, in association with the tonB protein. May play a role in intestinal colonization [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787024, Length=728, Percent_Identity=25.2747252747253, Blast_Score=168, Evalue=1e-42,
Organism=Escherichia coli, GI1786344, Length=730, Percent_Identity=25.4794520547945, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1787344, Length=747, Percent_Identity=22.3560910307898, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1790743, Length=364, Percent_Identity=22.2527472527473, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 75723; Mature: 75592

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHFTRSRTWVSLAVFAACAPAHAEQETLVITSQQSQLPEVATATRTATPAKLVPQTIDS
CCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCHHCCCHHHHHHCCCCCHHHHHHHHHH
LSAEELTAFGAPSLSEALAGVPGVNANGDTRFDGINIRGFSASNDFYLDGFRDDMQYTRD
CCHHHHHHCCCCCHHHHHCCCCCCCCCCCCEECCEEEEEECCCCCEEECCCHHHHHHHHH
LGNIERIEVLKGPAAVLYGRGSTGGIVNRVSKVPHAGDAASVSARIGSHDYQRLAADLNG
CCCCEEEEEECCCEEEEEECCCCCHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHCCC
EVNQQVQVRLNIAQEDYGSFRHGVEGKRTLLAPSLNWDINDDVSWLIQYEQHSHNRVPDR
CCCCEEEEEEEECHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEEEEHHHCCCCCCCC
GIPAVNGSPAEVPASSVYSDTSRDFIDDDVATTRSRITWAFHPEWQLRQQLSYTKLDSQF
CCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCC
DNTYVARVSGDQVTRQRFQQDLQANNLISNTETEGTFNTGPIAHRILIGLEQGWQERSPK
CCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCH
LYRNANSIPSGNLYQPESLPTYNGPMSVFSDATHKVRSYGIYVQDQLQWGDWIVLAGLRH
HHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEECCC
DDFTVTTHRHDTHKEETISSNSLSPRLGVVWTPVQEHALYASYSQTYSPVGGGVIGITPG
CCEEEEECCCCCCHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCCCCCEEEECCC
DKHNHLDPEHSRLYETGVKSDWLEGRISTTLSVYRLEMYNRRMRDPNDQERIILTGLQRT
CCCCCCCCHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC
DGIELSSRALLTDEFSLRGGIGLQDAKYVEADASEQGKRPTNVSRLNGELFVAYQSASDG
CCCCCCCCEEEEECCCCCCCCCCCCCCEEECCCHHCCCCCCCHHHCCCEEEEEEECCCCC
WFGETGFVAVGDRYADRTNTTKLPGYARFDARLGYQWQAWRTQLSVENLLDKDYYLSATS
CCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCEEHHHHHHHHHHHHCCCCEEEEECC
STQIQPGAPREFYLTASYQF
CCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure 
SHFTRSRTWVSLAVFAACAPAHAEQETLVITSQQSQLPEVATATRTATPAKLVPQTIDS
CCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCHHCCCHHHHHHCCCCCHHHHHHHHHH
LSAEELTAFGAPSLSEALAGVPGVNANGDTRFDGINIRGFSASNDFYLDGFRDDMQYTRD
CCHHHHHHCCCCCHHHHHCCCCCCCCCCCCEECCEEEEEECCCCCEEECCCHHHHHHHHH
LGNIERIEVLKGPAAVLYGRGSTGGIVNRVSKVPHAGDAASVSARIGSHDYQRLAADLNG
CCCCEEEEEECCCEEEEEECCCCCHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHCCC
EVNQQVQVRLNIAQEDYGSFRHGVEGKRTLLAPSLNWDINDDVSWLIQYEQHSHNRVPDR
CCCCEEEEEEEECHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEEEEHHHCCCCCCCC
GIPAVNGSPAEVPASSVYSDTSRDFIDDDVATTRSRITWAFHPEWQLRQQLSYTKLDSQF
CCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCC
DNTYVARVSGDQVTRQRFQQDLQANNLISNTETEGTFNTGPIAHRILIGLEQGWQERSPK
CCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCH
LYRNANSIPSGNLYQPESLPTYNGPMSVFSDATHKVRSYGIYVQDQLQWGDWIVLAGLRH
HHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEECCC
DDFTVTTHRHDTHKEETISSNSLSPRLGVVWTPVQEHALYASYSQTYSPVGGGVIGITPG
CCEEEEECCCCCCHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCCCCCEEEECCC
DKHNHLDPEHSRLYETGVKSDWLEGRISTTLSVYRLEMYNRRMRDPNDQERIILTGLQRT
CCCCCCCCHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC
DGIELSSRALLTDEFSLRGGIGLQDAKYVEADASEQGKRPTNVSRLNGELFVAYQSASDG
CCCCCCCCEEEEECCCCCCCCCCCCCCEEECCCHHCCCCCCCHHHCCCEEEEEEECCCCC
WFGETGFVAVGDRYADRTNTTKLPGYARFDARLGYQWQAWRTQLSVENLLDKDYYLSATS
CCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCEEHHHHHHHHHHHHCCCCEEEEECC
STQIQPGAPREFYLTASYQF
CCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258; 7642488 [H]