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The map label for this gene is murQ [H]

Identifier: 227080427

GI number: 227080427

Start: 199496

End: 200413

Strand: Direct

Name: murQ [H]

Synonym: VCM66_0194

Alternate gene names: 227080427

Gene position: 199496-200413 (Clockwise)

Preceding gene: 227080426

Following gene: 227080428

Centisome position: 6.9

GC content: 53.59

Gene sequence:

>918_bases
TTGCCGAGAAGCCTTATGAAGATTGATTTAACCCGCTTAGTGACCGAAAGCCGTAATCCAGCCAGTGAGCAGATTGATAC
CTTGTCCACGTTGGACATGCTGAAAGTGATTAACCAACAAGATCAGTTGGTTGCCTTGGCGGTTGCACAAACTTTGCCGC
AAGTGGCGCAAGCGGTGGAAGCGATTACCGCTGCTTTTGCTCAAGGTGGACGCTTGATTTATATGGGCGCAGGTACGTCT
GGTCGTTTAGGGATTCTCGATGCGAGTGAATGTCCGCCGACCTACGGTAGCAAGCCTGAACAGGTGATTGGCTTGATCGC
CGGTGGACATACGGCGATTTTGAAAGCAGTCGAAAATGCCGAAGACAACCGCGAGCTAGGCCAAAGCGATCTTAAGGCCC
TGAACCTTAATGAAAAGGATGTACTGGTTGGCATCGCCGCCAGTGGCCGTACCCCTTATGTGATTGGGGGAATGGAGTAC
GCACGCTCGGTCGGTACCACCGTAGTATCACTGGCGTGCAACCCGGGCTGCCCGATGGAGGCGTGCGCGGATATTGTGAT
TACCCCCGTAGTCGGTGCGGAAGTGGTTACGGGATCATCACGTATGAAAGCGGGCACTGCGCAGAAACTGGTGCTCAATA
TGCTGACCACGGGAGCGATGATCAAAAGTGGCAAAGTGTTTGGCAACCTGATGGTGGATGTGGAAGCGACCAACGCCAAG
CTCATCCAACGGCAAACCAATATTGTAGTAGAAGCGACAGGCGTAAGCGCTGAGCAAGCGGAAGCCGCATTGGCCGCGTG
TGGTCGCCACTGTAAGACCGCCATTTTGATGATATTGGGGGGCTTTAGTGCAGAGCAAGCCGCACAAAAACTGGCGCAGC
ACCAAGGCTTTATCCGCGCAGCGCTCAACCAAGAATAA

Upstream 100 bases:

>100_bases
CGATTATTCCAAAAAACGCCTGCTTAAAGAATAACCTTAATTGTGATTCTTATCACCAAAATGGAATATTTTATTCCATA
GAATCGCCTCAATTCGAAAT

Downstream 100 bases:

>100_bases
ACAGCAGAGAGAAGGAGCCGATGATGGCCAAAATAACCCAAACCATGATGGCACAAGTGCTGTCTCTGGTGGGCGGCAGT
GGTAACGTCGCCAAATGTGG

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase 1; N-acetylmuramic acid 6-phosphate hydrolase 1; N-acetylmuramic acid 6-phosphate lyase 1 [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MPRSLMKIDLTRLVTESRNPASEQIDTLSTLDMLKVINQQDQLVALAVAQTLPQVAQAVEAITAAFAQGGRLIYMGAGTS
GRLGILDASECPPTYGSKPEQVIGLIAGGHTAILKAVENAEDNRELGQSDLKALNLNEKDVLVGIAASGRTPYVIGGMEY
ARSVGTTVVSLACNPGCPMEACADIVITPVVGAEVVTGSSRMKAGTAQKLVLNMLTTGAMIKSGKVFGNLMVDVEATNAK
LIQRQTNIVVEATGVSAEQAEAALAACGRHCKTAILMILGGFSAEQAAQKLAQHQGFIRAALNQE

Sequences:

>Translated_305_residues
MPRSLMKIDLTRLVTESRNPASEQIDTLSTLDMLKVINQQDQLVALAVAQTLPQVAQAVEAITAAFAQGGRLIYMGAGTS
GRLGILDASECPPTYGSKPEQVIGLIAGGHTAILKAVENAEDNRELGQSDLKALNLNEKDVLVGIAASGRTPYVIGGMEY
ARSVGTTVVSLACNPGCPMEACADIVITPVVGAEVVTGSSRMKAGTAQKLVLNMLTTGAMIKSGKVFGNLMVDVEATNAK
LIQRQTNIVVEATGVSAEQAEAALAACGRHCKTAILMILGGFSAEQAAQKLAQHQGFIRAALNQE
>Mature_304_residues
PRSLMKIDLTRLVTESRNPASEQIDTLSTLDMLKVINQQDQLVALAVAQTLPQVAQAVEAITAAFAQGGRLIYMGAGTSG
RLGILDASECPPTYGSKPEQVIGLIAGGHTAILKAVENAEDNRELGQSDLKALNLNEKDVLVGIAASGRTPYVIGGMEYA
RSVGTTVVSLACNPGCPMEACADIVITPVVGAEVVTGSSRMKAGTAQKLVLNMLTTGAMIKSGKVFGNLMVDVEATNAKL
IQRQTNIVVEATGVSAEQAEAALAACGRHCKTAILMILGGFSAEQAAQKLAQHQGFIRAALNQE

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=298, Percent_Identity=64.0939597315436, Blast_Score=383, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31816; Mature: 31685

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRSLMKIDLTRLVTESRNPASEQIDTLSTLDMLKVINQQDQLVALAVAQTLPQVAQAVE
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AITAAFAQGGRLIYMGAGTSGRLGILDASECPPTYGSKPEQVIGLIAGGHTAILKAVENA
HHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHEEEEHCCCHHHHHHHHHCC
EDNRELGQSDLKALNLNEKDVLVGIAASGRTPYVIGGMEYARSVGTTVVSLACNPGCPME
HHHHHHCHHHHHEECCCCCEEEEEEECCCCCCEEECCHHHHHHHCCEEEEEECCCCCCHH
ACADIVITPVVGAEVVTGSSRMKAGTAQKLVLNMLTTGAMIKSGKVFGNLMVDVEATNAK
HHHHEEEECCCCCEEEECCCHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHH
LIQRQTNIVVEATGVSAEQAEAALAACGRHCKTAILMILGGFSAEQAAQKLAQHQGFIRA
HHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHH
ALNQE
HCCCC
>Mature Secondary Structure 
PRSLMKIDLTRLVTESRNPASEQIDTLSTLDMLKVINQQDQLVALAVAQTLPQVAQAVE
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AITAAFAQGGRLIYMGAGTSGRLGILDASECPPTYGSKPEQVIGLIAGGHTAILKAVENA
HHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHEEEEHCCCHHHHHHHHHCC
EDNRELGQSDLKALNLNEKDVLVGIAASGRTPYVIGGMEYARSVGTTVVSLACNPGCPME
HHHHHHCHHHHHEECCCCCEEEEEEECCCCCCEEECCHHHHHHHCCEEEEEECCCCCCHH
ACADIVITPVVGAEVVTGSSRMKAGTAQKLVLNMLTTGAMIKSGKVFGNLMVDVEATNAK
HHHHEEEECCCCCEEEECCCHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHH
LIQRQTNIVVEATGVSAEQAEAALAACGRHCKTAILMILGGFSAEQAAQKLAQHQGFIRA
HHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHH
ALNQE
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]