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The map label for this gene is yabD [H]

Identifier: 227080339

GI number: 227080339

Start: 99832

End: 100599

Strand: Reverse

Name: yabD [H]

Synonym: VCM66_0103

Alternate gene names: 227080339

Gene position: 100599-99832 (Counterclockwise)

Preceding gene: 227080340

Following gene: 227080338

Centisome position: 3.48

GC content: 45.96

Gene sequence:

>768_bases
ATGATTGATACCCATGCCCACGTTTATGCCAGTGAATTTGACCATGACCGCGATGAGGTGATCGCTCGCGCTAGACAAGT
CGGTATTGAAAAAATCTTGATGCCTAATATTGACCTCAATTCCATTGCGCCCATGTTGGCAACAGAAAAAGCCTACCCAG
ATCTTTGCCATTCGATGATGGGACTCCACCCTTGCTATGTGGATGCCAATGTAAAACAGACTTTAGCGACCATTTATGAG
TGGTTTTCTCGCCACACTTTTATTGCCGTGGGCGAAATCGGTATCGACCTATATTGGGATAAGACTTTTAAAGCCGAACA
AGAAATGGCGTTTTTAACCCAACTCAACTGGGCAAAAGAGCTGGATTTGCCCGTGGTCATTCACACCCGAGATTCGCTCA
ACGAGACATTAGCATTACTCAAGCAAGCGCAAGATGGTCGCTTACGCGGTGTTTTTCACTGCTTTGGCGGCAGTGTCGAC
GAGGCAAAAGCGATCAATGATCTTGGTTTTCATCTCGGCATTGGCGGAGTCAGTACTTTTAAAAATAGCGGCATGGATCA
AGTGATCCCGCAACTCGATCTCAACTACGTGATTTTAGAAACGGACTGTCCCTATTTAGCCCCCGTCCCCCACCGTGGAA
AACGTAATGAACCTATGTTAACCCATCTCATCAGTGAGAAAGTTGCACAGCTTCGTTCACTCCCTCTCGGCGAGGTTATC
AAAATTACCAACAACAATTCTAAGGCATTGTTTGGACTGGATAAATGA

Upstream 100 bases:

>100_bases
TCGGCTCGGCATGCTAGCGGCAAAGCAGGAAAAAGCCAAAAATGACCTCGTGCTCACACTCACGTATACTCGCCACAAAA
CCGAATGTTGAGATGATCCG

Downstream 100 bases:

>100_bases
CAGTTTTATTAATTTAATTTCATAGCATTTTATTGAACCAAGATCACTTTCATTTCCTATGCAGCAAATGTAATATTCGT
AACAATTTTTCATGGTTAAC

Product: Putative deoxyribonuclease yabD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MIDTHAHVYASEFDHDRDEVIARARQVGIEKILMPNIDLNSIAPMLATEKAYPDLCHSMMGLHPCYVDANVKQTLATIYE
WFSRHTFIAVGEIGIDLYWDKTFKAEQEMAFLTQLNWAKELDLPVVIHTRDSLNETLALLKQAQDGRLRGVFHCFGGSVD
EAKAINDLGFHLGIGGVSTFKNSGMDQVIPQLDLNYVILETDCPYLAPVPHRGKRNEPMLTHLISEKVAQLRSLPLGEVI
KITNNNSKALFGLDK

Sequences:

>Translated_255_residues
MIDTHAHVYASEFDHDRDEVIARARQVGIEKILMPNIDLNSIAPMLATEKAYPDLCHSMMGLHPCYVDANVKQTLATIYE
WFSRHTFIAVGEIGIDLYWDKTFKAEQEMAFLTQLNWAKELDLPVVIHTRDSLNETLALLKQAQDGRLRGVFHCFGGSVD
EAKAINDLGFHLGIGGVSTFKNSGMDQVIPQLDLNYVILETDCPYLAPVPHRGKRNEPMLTHLISEKVAQLRSLPLGEVI
KITNNNSKALFGLDK
>Mature_255_residues
MIDTHAHVYASEFDHDRDEVIARARQVGIEKILMPNIDLNSIAPMLATEKAYPDLCHSMMGLHPCYVDANVKQTLATIYE
WFSRHTFIAVGEIGIDLYWDKTFKAEQEMAFLTQLNWAKELDLPVVIHTRDSLNETLALLKQAQDGRLRGVFHCFGGSVD
EAKAINDLGFHLGIGGVSTFKNSGMDQVIPQLDLNYVILETDCPYLAPVPHRGKRNEPMLTHLISEKVAQLRSLPLGEVI
KITNNNSKALFGLDK

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=266, Percent_Identity=27.0676691729323, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI110349730, Length=266, Percent_Identity=26.6917293233083, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI226061853, Length=274, Percent_Identity=26.6423357664234, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI226061614, Length=254, Percent_Identity=26.7716535433071, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI226061595, Length=231, Percent_Identity=25.5411255411255, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI14042943, Length=270, Percent_Identity=25.1851851851852, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787342, Length=258, Percent_Identity=29.8449612403101, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI87082439, Length=256, Percent_Identity=32.03125, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI48994985, Length=259, Percent_Identity=30.1158301158301, Blast_Score=120, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71980746, Length=262, Percent_Identity=27.4809160305344, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=25.6227758007117, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17543026, Length=233, Percent_Identity=27.0386266094421, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17565396, Length=216, Percent_Identity=28.2407407407407, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24648690, Length=290, Percent_Identity=25.5172413793103, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28628; Mature: 28628

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDTHAHVYASEFDHDRDEVIARARQVGIEKILMPNIDLNSIAPMLATEKAYPDLCHSMM
CCCCCCCHHHHHCCCCHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHH
GLHPCYVDANVKQTLATIYEWFSRHTFIAVGEIGIDLYWDKTFKAEQEMAFLTQLNWAKE
CCCCEEECCHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCCCHHHHHHHHHHHCCHHH
LDLPVVIHTRDSLNETLALLKQAQDGRLRGVFHCFGGSVDEAKAINDLGFHLGIGGVSTF
CCCCEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCHHCCCCCHHHH
KNSGMDQVIPQLDLNYVILETDCPYLAPVPHRGKRNEPMLTHLISEKVAQLRSLPLGEVI
HCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEE
KITNNNSKALFGLDK
EEECCCCEEEEECCC
>Mature Secondary Structure
MIDTHAHVYASEFDHDRDEVIARARQVGIEKILMPNIDLNSIAPMLATEKAYPDLCHSMM
CCCCCCCHHHHHCCCCHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHH
GLHPCYVDANVKQTLATIYEWFSRHTFIAVGEIGIDLYWDKTFKAEQEMAFLTQLNWAKE
CCCCEEECCHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCCCHHHHHHHHHHHCCHHH
LDLPVVIHTRDSLNETLALLKQAQDGRLRGVFHCFGGSVDEAKAINDLGFHLGIGGVSTF
CCCCEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCHHCCCCCHHHH
KNSGMDQVIPQLDLNYVILETDCPYLAPVPHRGKRNEPMLTHLISEKVAQLRSLPLGEVI
HCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEE
KITNNNSKALFGLDK
EEECCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]