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The map label for this gene is yqfA [H]

Identifier: 227080277

GI number: 227080277

Start: 37847

End: 38494

Strand: Direct

Name: yqfA [H]

Synonym: VCM66_0040

Alternate gene names: 227080277

Gene position: 37847-38494 (Clockwise)

Preceding gene: 227080276

Following gene: 227080284

Centisome position: 1.31

GC content: 47.22

Gene sequence:

>648_bases
GTGAGTATGTCGAACAGTTATGGCTTTAAAGAAGAAGTGGCCAATGCGATAAGTCATGGCGTTGGCCTTATCTTAGGGAT
AGTTGGTTTAGTGCTGCTGTTGGTCAAAGCGGTGGATCAGCAAGCCGATGCATTGACTATTACCAGCATGAGCATTTATG
GCGGCAGTATGATTGCGCTATTTTTGGCTTCTACGCTGTACCACGCTATCCCTTATCAGCGTGCAAAGCGTTGGCTAAAA
ACCTTTGATCACTGTGCTATTTATTTACTGATTGCGGGCAGTTATACCCCATTTTTACTGGTCAGTTTGCGTACACCACT
GGCGGTTGGTTTGATGATAGTGATCTGGTCGCTCGCGCTTATTGGCATTCTGATGAAAATTGCTTTTGTCTACCGCTTCA
AAAAGCTCTCTTTGGTGACGTATCTGACCATGGGTTGGCTTTCGCTGATCGTGATTTACCAGCTTGCCATTCATCTTGAG
GTGGGTGGGCTCACTCTGCTGGCGGCAGGTGGACTTATCTATTCACTCGGGGTGATTTTCTACGTCGCCAAACGGATCCC
TTACAACCATGCCATTTGGCACGCTTTTGTGCTGGCGGGATGCGCATGCCATTTCTTAGCCATTTATCTGTATGTCGAGC
CGATTTAG

Upstream 100 bases:

>100_bases
CGTTTCTTGATCGCAGCTGCTGATCACGCGGTCTGAAATTTTAGCTAACACCTGTAAGCTCAATGTGCGATACTAAAGCC
AAGTTTCAGACTCGGATTGA

Downstream 100 bases:

>100_bases
CTTTGACGGATAAGATGGGTAAAAGAGGAAACGCGCATTTAGCGCGTTTCAATCTGTTTGATGGTAGCGTGTAGTGTGTA
CTGACTCTGCTCTGCGAGGT

Product: putative hemolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MSMSNSYGFKEEVANAISHGVGLILGIVGLVLLLVKAVDQQADALTITSMSIYGGSMIALFLASTLYHAIPYQRAKRWLK
TFDHCAIYLLIAGSYTPFLLVSLRTPLAVGLMIVIWSLALIGILMKIAFVYRFKKLSLVTYLTMGWLSLIVIYQLAIHLE
VGGLTLLAAGGLIYSLGVIFYVAKRIPYNHAIWHAFVLAGCACHFLAIYLYVEPI

Sequences:

>Translated_215_residues
MSMSNSYGFKEEVANAISHGVGLILGIVGLVLLLVKAVDQQADALTITSMSIYGGSMIALFLASTLYHAIPYQRAKRWLK
TFDHCAIYLLIAGSYTPFLLVSLRTPLAVGLMIVIWSLALIGILMKIAFVYRFKKLSLVTYLTMGWLSLIVIYQLAIHLE
VGGLTLLAAGGLIYSLGVIFYVAKRIPYNHAIWHAFVLAGCACHFLAIYLYVEPI
>Mature_214_residues
SMSNSYGFKEEVANAISHGVGLILGIVGLVLLLVKAVDQQADALTITSMSIYGGSMIALFLASTLYHAIPYQRAKRWLKT
FDHCAIYLLIAGSYTPFLLVSLRTPLAVGLMIVIWSLALIGILMKIAFVYRFKKLSLVTYLTMGWLSLIVIYQLAIHLEV
GGLTLLAAGGLIYSLGVIFYVAKRIPYNHAIWHAFVLAGCACHFLAIYLYVEPI

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI52630445, Length=214, Percent_Identity=35.981308411215, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI154759275, Length=208, Percent_Identity=33.1730769230769, Blast_Score=105, Evalue=2e-23,
Organism=Homo sapiens, GI154759277, Length=232, Percent_Identity=29.7413793103448, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1789266, Length=210, Percent_Identity=72.8571428571428, Blast_Score=312, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI71996356, Length=211, Percent_Identity=33.175355450237, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24640324, Length=228, Percent_Identity=32.4561403508772, Blast_Score=94, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 23664; Mature: 23533

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMSNSYGFKEEVANAISHGVGLILGIVGLVLLLVKAVDQQADALTITSMSIYGGSMIAL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCHHHHHH
FLASTLYHAIPYQRAKRWLKTFDHCAIYLLIAGSYTPFLLVSLRTPLAVGLMIVIWSLAL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGILMKIAFVYRFKKLSLVTYLTMGWLSLIVIYQLAIHLEVGGLTLLAAGGLIYSLGVIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHH
YVAKRIPYNHAIWHAFVLAGCACHFLAIYLYVEPI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SMSNSYGFKEEVANAISHGVGLILGIVGLVLLLVKAVDQQADALTITSMSIYGGSMIAL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCHHHHHH
FLASTLYHAIPYQRAKRWLKTFDHCAIYLLIAGSYTPFLLVSLRTPLAVGLMIVIWSLAL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGILMKIAFVYRFKKLSLVTYLTMGWLSLIVIYQLAIHLEVGGLTLLAAGGLIYSLGVIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHH
YVAKRIPYNHAIWHAFVLAGCACHFLAIYLYVEPI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]