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The map label for this gene is mshA [H]

Identifier: 226950531

GI number: 226950531

Start: 3528796

End: 3529890

Strand: Reverse

Name: mshA [H]

Synonym: CLM_3507

Alternate gene names: 226950531

Gene position: 3529890-3528796 (Counterclockwise)

Preceding gene: 226950532

Following gene: 226950530

Centisome position: 84.95

GC content: 28.4

Gene sequence:

>1095_bases
ATGAAAATATGTTATTTAGCTGATGCTAATAGTACACATACTAAAAAATGGTGTAGATTTTTTAAGAATAAAGGATATGA
TATAGATGTAATATCATTAAATGATGGAGAGATAGATGGGGTTGTTGTACATAGTTTTAACAAAGATTTAGATAAGATAA
GAAAAGGAAGCTCTTTTAATAAAATTTCTTATATAAAATATTTTAGTGATATAAAAAAAATTATAGAAAAAATAAAACCA
GATGTTGTTCATGCTCATTATGCTACTAGTTATGGTTTATTAGGAGCATTGTCAGGATTTCATCCCTATATAATATCCGT
TTGGGGTAGTGATGTATATGATTTCCCTAAGGGGAGTTATATAAAAAGAAAAATGGTTGAGTATAATTTATCCAAAGCAG
ATATTATAATGTCTACCAGTAAAGTAATGGCAGAAGAGACAAGTCAGTATACTACTAAAAATATAGAAATAACACCTTTT
GGAGTAAATATAGATACATTTAAGCCTTTCGCCGATAAATATGAAAAAAAAGAAAATTTAGTAATAGGTACAGTTAAAAC
ATTAGAGCCTAAATATGGTATAGAGTACTTAGTTAGAGCTTTTGCAAAGGTAAAGCAAAAACATAGTAATATTAAGTTAG
AAATTGCAGGGGTAGGAGAGCAAAGAAACTTTTTACTTAATCTATGTAATGAACTTAATGTAAAAGACCATGTTAAATTT
TTAGGATTTATAAATCAAGAAAAGGTAATAGAAGCTTTTAATAGGTTTGATGTAGCTGTATTTCCTTCCACATTAGATAG
TGAAAGTTTCGGGGTAGCGGCAGTAGAAGCACAGGCATGCGGAACTCCAGTAATTGTTTCTAATGTAGGAGGATTACCTG
AAGCTACGTCTCCTAATAATAGTAGTTTATTAGTAAATAAAAAAAGTGTAGATGAGTTAGCAGAGGCTATAGAAAAATTA
ATTGGGGATGACAATTTAAGGATAAATATGGGTAAAACCGCAAGGAAGTTTGTGGAAGATAATTTTAATATAGAAGATAA
TTTTAATAATGTAGATATAATATATAAATCTATAATAGATGGAGGAGATAATTAA

Upstream 100 bases:

>100_bases
ATAGATAATATTATTAATAAACATACATGGAAAGCTAGAGCTATAAAAGTAGTAGAGGATTTAACAAATCTTCAATAATA
CTTTTAATGGAGGAATAATA

Downstream 100 bases:

>100_bases
TGAAGATATTAACAGTAGTTGGTGCACGTCCACAATTTATAAAAGCAGCAGCGGTTTCAAATATAATAAGAAAAGAGCAT
ACGGAAGTATTAGTTCATAC

Product: group 1 glycosyl transferase family

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MKICYLADANSTHTKKWCRFFKNKGYDIDVISLNDGEIDGVVVHSFNKDLDKIRKGSSFNKISYIKYFSDIKKIIEKIKP
DVVHAHYATSYGLLGALSGFHPYIISVWGSDVYDFPKGSYIKRKMVEYNLSKADIIMSTSKVMAEETSQYTTKNIEITPF
GVNIDTFKPFADKYEKKENLVIGTVKTLEPKYGIEYLVRAFAKVKQKHSNIKLEIAGVGEQRNFLLNLCNELNVKDHVKF
LGFINQEKVIEAFNRFDVAVFPSTLDSESFGVAAVEAQACGTPVIVSNVGGLPEATSPNNSSLLVNKKSVDELAEAIEKL
IGDDNLRINMGKTARKFVEDNFNIEDNFNNVDIIYKSIIDGGDN

Sequences:

>Translated_364_residues
MKICYLADANSTHTKKWCRFFKNKGYDIDVISLNDGEIDGVVVHSFNKDLDKIRKGSSFNKISYIKYFSDIKKIIEKIKP
DVVHAHYATSYGLLGALSGFHPYIISVWGSDVYDFPKGSYIKRKMVEYNLSKADIIMSTSKVMAEETSQYTTKNIEITPF
GVNIDTFKPFADKYEKKENLVIGTVKTLEPKYGIEYLVRAFAKVKQKHSNIKLEIAGVGEQRNFLLNLCNELNVKDHVKF
LGFINQEKVIEAFNRFDVAVFPSTLDSESFGVAAVEAQACGTPVIVSNVGGLPEATSPNNSSLLVNKKSVDELAEAIEKL
IGDDNLRINMGKTARKFVEDNFNIEDNFNNVDIIYKSIIDGGDN
>Mature_364_residues
MKICYLADANSTHTKKWCRFFKNKGYDIDVISLNDGEIDGVVVHSFNKDLDKIRKGSSFNKISYIKYFSDIKKIIEKIKP
DVVHAHYATSYGLLGALSGFHPYIISVWGSDVYDFPKGSYIKRKMVEYNLSKADIIMSTSKVMAEETSQYTTKNIEITPF
GVNIDTFKPFADKYEKKENLVIGTVKTLEPKYGIEYLVRAFAKVKQKHSNIKLEIAGVGEQRNFLLNLCNELNVKDHVKF
LGFINQEKVIEAFNRFDVAVFPSTLDSESFGVAAVEAQACGTPVIVSNVGGLPEATSPNNSSLLVNKKSVDELAEAIEKL
IGDDNLRINMGKTARKFVEDNFNIEDNFNNVDIIYKSIIDGGDN

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=206, Percent_Identity=27.6699029126214, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788357, Length=341, Percent_Identity=22.5806451612903, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17532709, Length=301, Percent_Identity=20.5980066445183, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI9755344, Length=265, Percent_Identity=24.5283018867925, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24654571, Length=328, Percent_Identity=22.5609756097561, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 40869; Mature: 40869

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKICYLADANSTHTKKWCRFFKNKGYDIDVISLNDGEIDGVVVHSFNKDLDKIRKGSSFN
CEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCHHHHHCCCCCC
KISYIKYFSDIKKIIEKIKPDVVHAHYATSYGLLGALSGFHPYIISVWGSDVYDFPKGSY
HHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCH
IKRKMVEYNLSKADIIMSTSKVMAEETSQYTTKNIEITPFGVNIDTFKPFADKYEKKENL
HHHHHHHHCCCHHHEEEHHHHHHHHHHHHHEECCEEEEEECCCCCCCCHHHHHHHCCCCE
VIGTVKTLEPKYGIEYLVRAFAKVKQKHSNIKLEIAGVGEQRNFLLNLCNELNVKDHVKF
EEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCHHHHHHH
LGFINQEKVIEAFNRFDVAVFPSTLDSESFGVAAVEAQACGTPVIVSNVGGLPEATSPNN
HHCCCHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEHHHCCCCEEEECCCCCCCCCCCCC
SSLLVNKKSVDELAEAIEKLIGDDNLRINMGKTARKFVEDNFNIEDNFNNVDIIYKSIID
CEEEEEHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHHHC
GGDN
CCCC
>Mature Secondary Structure
MKICYLADANSTHTKKWCRFFKNKGYDIDVISLNDGEIDGVVVHSFNKDLDKIRKGSSFN
CEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCHHHHHCCCCCC
KISYIKYFSDIKKIIEKIKPDVVHAHYATSYGLLGALSGFHPYIISVWGSDVYDFPKGSY
HHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCH
IKRKMVEYNLSKADIIMSTSKVMAEETSQYTTKNIEITPFGVNIDTFKPFADKYEKKENL
HHHHHHHHCCCHHHEEEHHHHHHHHHHHHHEECCEEEEEECCCCCCCCHHHHHHHCCCCE
VIGTVKTLEPKYGIEYLVRAFAKVKQKHSNIKLEIAGVGEQRNFLLNLCNELNVKDHVKF
EEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCHHHHHHH
LGFINQEKVIEAFNRFDVAVFPSTLDSESFGVAAVEAQACGTPVIVSNVGGLPEATSPNN
HHCCCHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEHHHCCCCEEEECCCCCCCCCCCCC
SSLLVNKKSVDELAEAIEKLIGDDNLRINMGKTARKFVEDNFNIEDNFNNVDIIYKSIID
CEEEEEHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHHHC
GGDN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA