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The map label for this gene is ruvA [H]

Identifier: 226950500

GI number: 226950500

Start: 3497260

End: 3497853

Strand: Reverse

Name: ruvA [H]

Synonym: CLM_3476

Alternate gene names: 226950500

Gene position: 3497853-3497260 (Counterclockwise)

Preceding gene: 226950501

Following gene: 226950499

Centisome position: 84.18

GC content: 26.6

Gene sequence:

>594_bases
GTGTACGAATATATAAAAGGAAAATATATTGATATGTACAAAGACTATATAGTTATAGAAAATAATAATATAGGTTATAA
GATATACACATCAGGAAGTACTATGGCAAAATTACCTTCCATAGGTGAAAATATAATGTTATATACTGAGCAAATAGTAA
GAGAAGATTTTATAGGAGTTTATGGATTTTTAACAAAAGATGAGTTAAGCATGTTTAAATTGCTTTTAACAATAAATGGG
GTAGGGGCTAAGGCATCGTTATCTTTGTTATCTATAAGCAATGTTTCTACTTTGAAATATGCTATAAAAATGGGAGATGA
AAAAACTATAACAAGAGCTCCTGGTATAGGTAAAAAAACAGCTCAAAGAATTATATTAGAGCTTAAGGATAAGATAGAGA
TAGATATTTTAGAAGAAGATGATGAACAAATCATAAATAAGGTTACGGATGATAAAAAAGTATTAGAAGCAGTAGCTGCT
TTAGTAACACTAGGTTATTCTGAAAAAGAAGCAAATAAAGTGATTAATTCATGTGATAAAAATAATTCTTTAGAACAGAT
TATAAAGGAAGCTTTAAAATATTTAATGAAATAA

Upstream 100 bases:

>100_bases
ATTTACACTAATATGCAAGCTATGTTTTTTTAGTTGAATAAAAACTCCTAAAATGATAAAGTAATATATGTCTATTAATA
TGTAATTGGAGGGTTAAGGG

Downstream 100 bases:

>100_bases
ATTAGAGGGGGGTACTTATATGGAGAATAGAATGGTAACTCCTTTTGATGTAGAAGATGATAGGGAACAGTATAGCTTAA
GACCTACTACATTAAAAGAA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MYEYIKGKYIDMYKDYIVIENNNIGYKIYTSGSTMAKLPSIGENIMLYTEQIVREDFIGVYGFLTKDELSMFKLLLTING
VGAKASLSLLSISNVSTLKYAIKMGDEKTITRAPGIGKKTAQRIILELKDKIEIDILEEDDEQIINKVTDDKKVLEAVAA
LVTLGYSEKEANKVINSCDKNNSLEQIIKEALKYLMK

Sequences:

>Translated_197_residues
MYEYIKGKYIDMYKDYIVIENNNIGYKIYTSGSTMAKLPSIGENIMLYTEQIVREDFIGVYGFLTKDELSMFKLLLTING
VGAKASLSLLSISNVSTLKYAIKMGDEKTITRAPGIGKKTAQRIILELKDKIEIDILEEDDEQIINKVTDDKKVLEAVAA
LVTLGYSEKEANKVINSCDKNNSLEQIIKEALKYLMK
>Mature_197_residues
MYEYIKGKYIDMYKDYIVIENNNIGYKIYTSGSTMAKLPSIGENIMLYTEQIVREDFIGVYGFLTKDELSMFKLLLTING
VGAKASLSLLSISNVSTLKYAIKMGDEKTITRAPGIGKKTAQRIILELKDKIEIDILEEDDEQIINKVTDDKKVLEAVAA
LVTLGYSEKEANKVINSCDKNNSLEQIIKEALKYLMK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=201, Percent_Identity=33.3333333333333, Blast_Score=116, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 22229; Mature: 22229

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYEYIKGKYIDMYKDYIVIENNNIGYKIYTSGSTMAKLPSIGENIMLYTEQIVREDFIGV
CCCCCCCCEEEEECCEEEEECCCCCEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHH
YGFLTKDELSMFKLLLTINGVGAKASLSLLSISNVSTLKYAIKMGDEKTITRAPGIGKKT
HHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHCCCCCCEECCCCCCHHH
AQRIILELKDKIEIDILEEDDEQIINKVTDDKKVLEAVAALVTLGYSEKEANKVINSCDK
HHHHHHHHHCCEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
NNSLEQIIKEALKYLMK
CCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MYEYIKGKYIDMYKDYIVIENNNIGYKIYTSGSTMAKLPSIGENIMLYTEQIVREDFIGV
CCCCCCCCEEEEECCEEEEECCCCCEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHH
YGFLTKDELSMFKLLLTINGVGAKASLSLLSISNVSTLKYAIKMGDEKTITRAPGIGKKT
HHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHCCCCCCEECCCCCCHHH
AQRIILELKDKIEIDILEEDDEQIINKVTDDKKVLEAVAALVTLGYSEKEANKVINSCDK
HHHHHHHHHCCEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
NNSLEQIIKEALKYLMK
CCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA