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The map label for this gene is holA [H]

Identifier: 226950394

GI number: 226950394

Start: 3395743

End: 3396774

Strand: Reverse

Name: holA [H]

Synonym: CLM_3363

Alternate gene names: 226950394

Gene position: 3396774-3395743 (Counterclockwise)

Preceding gene: 226950395

Following gene: 226950392

Centisome position: 81.75

GC content: 23.16

Gene sequence:

>1032_bases
TTGTTAGATATACTAGAGTTTGAACAAAACACAAAGAAATATATAAATAATAATTGTTATATTTTTTGTGGACATCATGA
ACAATTGATAAAAGAAAATATAAAAAAAATAATAGATATTAATATAAATAATGATTTTAAAGATTTAAATTATCTTCAAT
TTGATGGGTCACAATTAGAAGAATTTGATACAGTGTTTAATGCCTGTGAAACATTGCCTTTTATGAGTGAGAAGAAAGCA
GTCTTAATTTATAGGGCAGGTTTTTTAGATGACAACAAGGGTGATAATAAAGCTAAAAAACTATATAAAGATATAGAGAA
TTATATAAAAAACATTCCATCTCATTGTATTTTTATTATGTATTATATTATGACAAATAAAAGGGATAAAGTAAGTTATA
AAATAAAAAAATTAGACAAGAAAGCCTGCATAGTTACTATTGATAAAATTAAGGGAGAAAATCTTGAAAAAAGAGTAGAA
AAATTTTTTAGTGATAGGGGGAAAAAGATAAGCAAAATACCATTAAAGGCCTTTATACAAACCATTGAAAATGAAAATCT
AAGTTATATAGAAAATGAAGTAGAAAAATTATGTACTTATGCAATGCATGAAGAAATAGAAAAGAAACATATAAAAGAAA
TGTATGAAAATATAAAAGATGAAGATATATTTGATTTAATAAATTTCATATCTGAAAAAAAACCACGAAAAGCTATAGAG
ATTTTAAATGAATTAATGTACAAAGGACAAAAAATAAATCATATATTAGTTATGATAGAAAAACAATTTAGAAATTTATA
TTTTGTAAAGATAGGTATGGAACAAGGAAAAACTAAAGAAGATTTAGCAAAAGAGTTAAAAATTCATCCCTATGGATGCA
GTGTTTTAATGAGCCAAAGTAAAAAGTTCACATTAAAACAAATAGAGAAGTCCATAGAATTAGTGATAGAAACAGATAAA
AAAATAAAAACTACTTCCGTTAATACGCAAACAGAAGTAGAATTATTAATAATAAATTCTATATGTGCTTAA

Upstream 100 bases:

>100_bases
GAAAAAAATTATACAGATATTTTAAATAAAAGATATATAGTAGTTTTTAATAAAATTTTATGTTTAAAATAAAGGAAATG
TTAAATAAGGAGTGAACATT

Downstream 100 bases:

>100_bases
AATAAATAAACCCGTTAAATACGGGTTATTTATTTTAAGCGTTTAATGCATTTAATTTTGCAGCTAATCTAGATTTTGTT
CTAGCAGCTTTGTTTTTGTG

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MLDILEFEQNTKKYINNNCYIFCGHHEQLIKENIKKIIDININNDFKDLNYLQFDGSQLEEFDTVFNACETLPFMSEKKA
VLIYRAGFLDDNKGDNKAKKLYKDIENYIKNIPSHCIFIMYYIMTNKRDKVSYKIKKLDKKACIVTIDKIKGENLEKRVE
KFFSDRGKKISKIPLKAFIQTIENENLSYIENEVEKLCTYAMHEEIEKKHIKEMYENIKDEDIFDLINFISEKKPRKAIE
ILNELMYKGQKINHILVMIEKQFRNLYFVKIGMEQGKTKEDLAKELKIHPYGCSVLMSQSKKFTLKQIEKSIELVIETDK
KIKTTSVNTQTEVELLIINSICA

Sequences:

>Translated_343_residues
MLDILEFEQNTKKYINNNCYIFCGHHEQLIKENIKKIIDININNDFKDLNYLQFDGSQLEEFDTVFNACETLPFMSEKKA
VLIYRAGFLDDNKGDNKAKKLYKDIENYIKNIPSHCIFIMYYIMTNKRDKVSYKIKKLDKKACIVTIDKIKGENLEKRVE
KFFSDRGKKISKIPLKAFIQTIENENLSYIENEVEKLCTYAMHEEIEKKHIKEMYENIKDEDIFDLINFISEKKPRKAIE
ILNELMYKGQKINHILVMIEKQFRNLYFVKIGMEQGKTKEDLAKELKIHPYGCSVLMSQSKKFTLKQIEKSIELVIETDK
KIKTTSVNTQTEVELLIINSICA
>Mature_343_residues
MLDILEFEQNTKKYINNNCYIFCGHHEQLIKENIKKIIDININNDFKDLNYLQFDGSQLEEFDTVFNACETLPFMSEKKA
VLIYRAGFLDDNKGDNKAKKLYKDIENYIKNIPSHCIFIMYYIMTNKRDKVSYKIKKLDKKACIVTIDKIKGENLEKRVE
KFFSDRGKKISKIPLKAFIQTIENENLSYIENEVEKLCTYAMHEEIEKKHIKEMYENIKDEDIFDLINFISEKKPRKAIE
ILNELMYKGQKINHILVMIEKQFRNLYFVKIGMEQGKTKEDLAKELKIHPYGCSVLMSQSKKFTLKQIEKSIELVIETDK
KIKTTSVNTQTEVELLIINSICA

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921
- InterPro:   IPR010372
- InterPro:   IPR005790 [H]

Pfam domain/function: PF06144 DNA_pol3_delta [H]

EC number: 2.7.7.7

Molecular weight: Translated: 40488; Mature: 40488

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDILEFEQNTKKYINNNCYIFCGHHEQLIKENIKKIIDININNDFKDLNYLQFDGSQLE
CCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHEEECCCCCCCCCCEEEECCHHHH
EFDTVFNACETLPFMSEKKAVLIYRAGFLDDNKGDNKAKKLYKDIENYIKNIPSHCIFIM
HHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
YYIMTNKRDKVSYKIKKLDKKACIVTIDKIKGENLEKRVEKFFSDRGKKISKIPLKAFIQ
HHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCEEHHCHHHHHHH
TIENENLSYIENEVEKLCTYAMHEEIEKKHIKEMYENIKDEDIFDLINFISEKKPRKAIE
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHH
ILNELMYKGQKINHILVMIEKQFRNLYFVKIGMEQGKTKEDLAKELKIHPYGCSVLMSQS
HHHHHHHCCCCCCHHHEEEEHHHCCEEEEEEECCCCCCHHHHHHHCCCCCCCHHHHHHCC
KKFTLKQIEKSIELVIETDKKIKTTSVNTQTEVELLIINSICA
CCHHHHHHHHHHHEEEECCCCEEEECCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MLDILEFEQNTKKYINNNCYIFCGHHEQLIKENIKKIIDININNDFKDLNYLQFDGSQLE
CCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHEEECCCCCCCCCCEEEECCHHHH
EFDTVFNACETLPFMSEKKAVLIYRAGFLDDNKGDNKAKKLYKDIENYIKNIPSHCIFIM
HHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
YYIMTNKRDKVSYKIKKLDKKACIVTIDKIKGENLEKRVEKFFSDRGKKISKIPLKAFIQ
HHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCEEHHCHHHHHHH
TIENENLSYIENEVEKLCTYAMHEEIEKKHIKEMYENIKDEDIFDLINFISEKKPRKAIE
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHH
ILNELMYKGQKINHILVMIEKQFRNLYFVKIGMEQGKTKEDLAKELKIHPYGCSVLMSQS
HHHHHHHCCCCCCHHHEEEEHHHCCEEEEEEECCCCCCHHHHHHHCCCCCCCHHHHHHCC
KKFTLKQIEKSIELVIETDKKIKTTSVNTQTEVELLIINSICA
CCHHHHHHHHHHHEEEECCCCEEEECCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]