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The map label for this gene is gsp [C]

Identifier: 226950336

GI number: 226950336

Start: 3334547

End: 3335155

Strand: Reverse

Name: gsp [C]

Synonym: CLM_3302

Alternate gene names: 226950336

Gene position: 3335155-3334547 (Counterclockwise)

Preceding gene: 226950337

Following gene: 226950335

Centisome position: 80.26

GC content: 26.11

Gene sequence:

>609_bases
ATGAGAAAAATATATAAGGGATTAATATTTTTAATTATTATCATTATTTTATTTATAGTTGGAAAAGCTTTTGTTTCAAA
TAAATTGCATCAAATGCTTTTACACAAAGAAAACAGCATAGGAGATGTATTAGATAGTTATAAAGAAGTAAATGTTTTTT
ATAATGGCAACAATTATGGAGAAAATCATGGTAAGAGCTATAGCAAAGATGGATATTATTATGGATATAAGTGGCAATGT
GTTGAATATGTAAAAAGATTTTATTATAAGGCTAAAGATCATAAAATGCCGGATGTTTATGGCAATGCTAAAGATTTCTT
TGATATTAATACAGAGCAGGGACATTTGAATAAAAGAAGAGGCTTAATTCAATACAGAAACGGAGAAAATGAAAAGCCTA
AAGTAGATGATCTTTTAGTATTTACAGATACTGAATTTGAACATGTAGTAATAGTTACAGAAGTTGGAAATGATTATATA
GAAGTAATTCAGCAAAATATAGGAAGTTCATCAAGAGATAAATTTACATTGAAATATAAAAATAAAAAATATTTTATTGG
AGGAAAAAGATCACCAGCAGGATGGCTCAGGAAAGTTAATTATAATTAA

Upstream 100 bases:

>100_bases
AAGTATTTCTTGTTTTAATTCTCAACCTTTAAAGGCTGTTATGTCATAATTTCGTTATACAGCTATGGTGTTGAATTTAT
AAAATGATAAGGAGACATAA

Downstream 100 bases:

>100_bases
AGATTTTGTGTAGATAATCGAAACAAAATCCTCCACATCTGTTCTCTGTACTCTATACTCTGTACTCTGAAAAGTGCAAC
GCACTTTCCTTAAGTGTTGA

Product: chap domain-containing protein

Products: ADP; Glutathionylspermidine; H+; Phosphate [C]

Alternate protein names: Trypanothione Synthetase Domain Protein; Amidase; Chap Domain Containing Protein; Trypanothione Synthetase Domain-Containing Protein; Chloride Channel

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MRKIYKGLIFLIIIIILFIVGKAFVSNKLHQMLLHKENSIGDVLDSYKEVNVFYNGNNYGENHGKSYSKDGYYYGYKWQC
VEYVKRFYYKAKDHKMPDVYGNAKDFFDINTEQGHLNKRRGLIQYRNGENEKPKVDDLLVFTDTEFEHVVIVTEVGNDYI
EVIQQNIGSSSRDKFTLKYKNKKYFIGGKRSPAGWLRKVNYN

Sequences:

>Translated_202_residues
MRKIYKGLIFLIIIIILFIVGKAFVSNKLHQMLLHKENSIGDVLDSYKEVNVFYNGNNYGENHGKSYSKDGYYYGYKWQC
VEYVKRFYYKAKDHKMPDVYGNAKDFFDINTEQGHLNKRRGLIQYRNGENEKPKVDDLLVFTDTEFEHVVIVTEVGNDYI
EVIQQNIGSSSRDKFTLKYKNKKYFIGGKRSPAGWLRKVNYN
>Mature_202_residues
MRKIYKGLIFLIIIIILFIVGKAFVSNKLHQMLLHKENSIGDVLDSYKEVNVFYNGNNYGENHGKSYSKDGYYYGYKWQC
VEYVKRFYYKAKDHKMPDVYGNAKDFFDINTEQGHLNKRRGLIQYRNGENEKPKVDDLLVFTDTEFEHVVIVTEVGNDYI
EVIQQNIGSSSRDKFTLKYKNKKYFIGGKRSPAGWLRKVNYN

Specific function: Catalyzes The Formation Of An Amide Bond Between Glutathione And Spermidine Coupled With Hydrolysis Of ATP; Also Catalyzes The Hydrolysis Of Glutathionylspermidine To Glutathione And Spermidine. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 6.3.1.8; 3.5.1.78 [C]

Molecular weight: Translated: 23804; Mature: 23804

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50911 CHAP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIYKGLIFLIIIIILFIVGKAFVSNKLHQMLLHKENSIGDVLDSYKEVNVFYNGNNYG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEECCCCCC
ENHGKSYSKDGYYYGYKWQCVEYVKRFYYKAKDHKMPDVYGNAKDFFDINTEQGHLNKRR
CCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCHHHC
GLIQYRNGENEKPKVDDLLVFTDTEFEHVVIVTEVGNDYIEVIQQNIGSSSRDKFTLKYK
CEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEECCCHHHHHHHHHCCCCCCCEEEEEEC
NKKYFIGGKRSPAGWLRKVNYN
CCEEEECCCCCCHHHEEECCCC
>Mature Secondary Structure
MRKIYKGLIFLIIIIILFIVGKAFVSNKLHQMLLHKENSIGDVLDSYKEVNVFYNGNNYG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEECCCCCC
ENHGKSYSKDGYYYGYKWQCVEYVKRFYYKAKDHKMPDVYGNAKDFFDINTEQGHLNKRR
CCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCHHHC
GLIQYRNGENEKPKVDDLLVFTDTEFEHVVIVTEVGNDYIEVIQQNIGSSSRDKFTLKYK
CEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEECCCHHHHHHHHHCCCCCCCEEEEEEC
NKKYFIGGKRSPAGWLRKVNYN
CCEEEECCCCCCHHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; Reduced glutathione; Spermidine [C]

Specific reaction: ATP + Reduced glutathione + Spermidine --> ADP + Glutathionylspermidine + H+ + Phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA