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The map label for this gene is fecD [C]

Identifier: 226950326

GI number: 226950326

Start: 3320799

End: 3321767

Strand: Direct

Name: fecD [C]

Synonym: CLM_3291

Alternate gene names: 226950326

Gene position: 3320799-3321767 (Clockwise)

Preceding gene: 226950325

Following gene: 226950327

Centisome position: 79.92

GC content: 31.68

Gene sequence:

>969_bases
ATGAACAAAATAAAAAAATACTTAATATTGCCTATAGGTATTACTCTAATTTTATTATCGATTTGTATGGGAAGATACTC
TATATCTTTGTATGATTTATATTCACTAAATGATAAAGCTACTGCTGTATTTTTTAATTTACGTTTACCCAGAATTATAG
CTGCCCTATTAGTTGGTGGAGCTTTATCTATTGCTGGTGCTTCTTATCAAGGTATGTTTAGAAATCCTTTAGTATCTCCT
GATATTTTAGGAGCATCTGCCGGTGCTAGCTTTGGTGTTGCAGTTGGCATATTGCTTTCTTTAAATGTTCAAACTATACA
ATTTTTTGCATTTATATTTGGTTTAATTGCAGTTATAAGCTCCTGGAGGATAAGTAGAAGAATTCCCCATCATGATCCAA
GTTTAGTATTAGTTTTATCTGGAATGTTAATACAAGGAATATTTACCTCTGGAGTATCTCTTGTAAAATATATATGTGAT
CCTTATGATAAACTGCCTGCTATAACCTTTTGGCTCATGGGCGGGTTATCTTCCATAACTTTAAAAGATCTAAAAGTTAT
GATAGTACCAATAATTTTAGGATTAATACCTTTACTTTTAATAAGATGGAAACTTAACATATTATCTTTTCCAGAAGAAG
AAGCAAAAACCTTAGGCGTAAATACAGATAGAATAAGAATTATTGTGATAATATGCTCCACCCTACTTAGTGCTTCAATC
GTTTCTTATTGTGGCGTTATTGGATGGGTAGGACTAGTTATTCCTCATTTAACAAGATCTCTATATGGACCTAATTATAA
AGTGTTACTCCCATCTTCTTTTCTTATAGGTAGTCTATATATGCTCTTAGTAGATGATCTCGCTAGATGTATGTTTTCCG
TGGAAGTTCCTCTTGGAATATTGACTTCTTTAATAGGAATACCATTTTTCGCTTATTTGTTAATAAATGTAAAGAAGGGT
TGGCTATGA

Upstream 100 bases:

>100_bases
AGGTTACTTTAAATAATAGAGATTATATTACAAACCATATATTAAATATATTAATTAATTGGAATATTCCCATGAAATTT
TATGAAAATGAGATGATTCC

Downstream 100 bases:

>100_bases
AATTAGAGATTAAAAAAGCTTCCTTTGGATATAGTGATACCATACTTTGCAAAAATTTATCCTTTGGTTTAAATCCAGGA
GAATTGCTATGTGTTCTCGG

Product: iron chelate uptake ABC transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MNKIKKYLILPIGITLILLSICMGRYSISLYDLYSLNDKATAVFFNLRLPRIIAALLVGGALSIAGASYQGMFRNPLVSP
DILGASAGASFGVAVGILLSLNVQTIQFFAFIFGLIAVISSWRISRRIPHHDPSLVLVLSGMLIQGIFTSGVSLVKYICD
PYDKLPAITFWLMGGLSSITLKDLKVMIVPIILGLIPLLLIRWKLNILSFPEEEAKTLGVNTDRIRIIVIICSTLLSASI
VSYCGVIGWVGLVIPHLTRSLYGPNYKVLLPSSFLIGSLYMLLVDDLARCMFSVEVPLGILTSLIGIPFFAYLLINVKKG
WL

Sequences:

>Translated_322_residues
MNKIKKYLILPIGITLILLSICMGRYSISLYDLYSLNDKATAVFFNLRLPRIIAALLVGGALSIAGASYQGMFRNPLVSP
DILGASAGASFGVAVGILLSLNVQTIQFFAFIFGLIAVISSWRISRRIPHHDPSLVLVLSGMLIQGIFTSGVSLVKYICD
PYDKLPAITFWLMGGLSSITLKDLKVMIVPIILGLIPLLLIRWKLNILSFPEEEAKTLGVNTDRIRIIVIICSTLLSASI
VSYCGVIGWVGLVIPHLTRSLYGPNYKVLLPSSFLIGSLYMLLVDDLARCMFSVEVPLGILTSLIGIPFFAYLLINVKKG
WL
>Mature_322_residues
MNKIKKYLILPIGITLILLSICMGRYSISLYDLYSLNDKATAVFFNLRLPRIIAALLVGGALSIAGASYQGMFRNPLVSP
DILGASAGASFGVAVGILLSLNVQTIQFFAFIFGLIAVISSWRISRRIPHHDPSLVLVLSGMLIQGIFTSGVSLVKYICD
PYDKLPAITFWLMGGLSSITLKDLKVMIVPIILGLIPLLLIRWKLNILSFPEEEAKTLGVNTDRIRIIVIICSTLLSASI
VSYCGVIGWVGLVIPHLTRSLYGPNYKVLLPSSFLIGSLYMLLVDDLARCMFSVEVPLGILTSLIGIPFFAYLLINVKKG
WL

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=311, Percent_Identity=34.4051446945338, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1790741, Length=277, Percent_Identity=31.7689530685921, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788004, Length=312, Percent_Identity=30.7692307692308, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1786805, Length=284, Percent_Identity=32.3943661971831, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1786347, Length=289, Percent_Identity=30.7958477508651, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786804, Length=282, Percent_Identity=26.5957446808511, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35236; Mature: 35236

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIKKYLILPIGITLILLSICMGRYSISLYDLYSLNDKATAVFFNLRLPRIIAALLVGG
CCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEEECCHHHHHHHHHHCC
ALSIAGASYQGMFRNPLVSPDILGASAGASFGVAVGILLSLNVQTIQFFAFIFGLIAVIS
HHHHCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
SWRISRRIPHHDPSLVLVLSGMLIQGIFTSGVSLVKYICDPYDKLPAITFWLMGGLSSIT
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHH
LKDLKVMIVPIILGLIPLLLIRWKLNILSFPEEEAKTLGVNTDRIRIIVIICSTLLSASI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VSYCGVIGWVGLVIPHLTRSLYGPNYKVLLPSSFLIGSLYMLLVDDLARCMFSVEVPLGI
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LTSLIGIPFFAYLLINVKKGWL
HHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKIKKYLILPIGITLILLSICMGRYSISLYDLYSLNDKATAVFFNLRLPRIIAALLVGG
CCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEEECCHHHHHHHHHHCC
ALSIAGASYQGMFRNPLVSPDILGASAGASFGVAVGILLSLNVQTIQFFAFIFGLIAVIS
HHHHCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
SWRISRRIPHHDPSLVLVLSGMLIQGIFTSGVSLVKYICDPYDKLPAITFWLMGGLSSIT
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHH
LKDLKVMIVPIILGLIPLLLIRWKLNILSFPEEEAKTLGVNTDRIRIIVIICSTLLSASI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VSYCGVIGWVGLVIPHLTRSLYGPNYKVLLPSSFLIGSLYMLLVDDLARCMFSVEVPLGI
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LTSLIGIPFFAYLLINVKKGWL
HHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]