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The map label for this gene is ribD [H]

Identifier: 226950300

GI number: 226950300

Start: 3283714

End: 3284811

Strand: Reverse

Name: ribD [H]

Synonym: CLM_3262

Alternate gene names: 226950300

Gene position: 3284811-3283714 (Counterclockwise)

Preceding gene: 226950301

Following gene: 226950299

Centisome position: 79.05

GC content: 31.6

Gene sequence:

>1098_bases
ATGGAAGATTATAATTTTTATATGGAAAAAGCCTTGAAACTAGCTGAAAGAGGTGAGGGTAAAGTTAATCCTAATCCTAA
AGTAGGAGCTATAGTAGTTAAGAACAACAAAATAATTGGAGAAGGTTATCACAAATATTTTGGAGGATCTCATGCAGAAG
TTTATGCTCTTAGAGAAGCAGGAGAAAAGGCTAAAGGGGCTACTATATATGTTACATTAGAGCCCTGCTCACATTATGGT
AAAACTCCTCCCTGTGCAGAGTCTATAGTAAAGATGGGAATATCTAAGGCTATTATAGCTATGAAAGATCCCAATCCTTT
AGTTGAGGGTAGAGGGATAGATATTTTAAAGCAAAATGGAATAGAAGTTGTAACAGGGATTATGGAAAAAGAAAGTAAAA
AATTAAATGAAGTCTTTATAAAATACATAACTAAAAAGAAACCTTTTGTAGTTTTAAAAACTGCTTCTACCTTAGATGGT
AAGATTGCTACAAGAACAGGAGAATCAAAATGGATAACAGGAGAAGATGCAAGATATAAAGTACAGCAAATAAGAAATGA
TTTATCCGGAATAATGGTAGGAATAGGGACAATTATAAAAGATAATCCTCTTTTAACTACAAGAATAGAAGGGGGAAGAA
GTCCAAGGGCAATAATAGTAGATTCCAATCTTAGAATTCCCTTAGAATCTAAAATATTAGAAACCCTTAATAAAAGAGCT
ATTTATATAGCAACAACTAAAAAACATAACAATTTTTCAAAAAAGAATGCTTTAGAAAATTTAGGGGCTAAGGTTTTAGA
GTTTGAGGAAAATGAAGAGGGAAAAGTTCCATTGAATGAATTAATGCAATATTTAGGATCAGAAGGAGTGGATAGTATTC
TTTTAGAAGGAGGCAGCACATTAAATTTTTCTGCACTAAAAGAAGGGATAGTAGATAAAGTTATGTGTTTTATAGCACCC
AAAATAATGGGAGGACAGGATTCAAAAAATATGATAGGTGGAAATGGGGTAGAAAGCTTAAAAGATATATTTAATCTACA
AAACTTAAAATTTGAAAAAATAGGGCAGGATATACTTATTGAAGGCTATGTATATTAG

Upstream 100 bases:

>100_bases
TTTAAAATTGTATACCAAAGCAAAAATTTAATACAAAAATGTATTTATATAATTACGATATTTGAGATTAAACAATAGCT
TTAAAGGCGGTGTATTTAAA

Downstream 100 bases:

>100_bases
AAAAGAGGGTGTTAGTTTGTTTACTGGCATAGTTGAGGAAGTCGGAAGAATATTAAAAATAGAGGAAGGAAAAGACTTTC
TTCACATCACCATAGAAGGA

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MEDYNFYMEKALKLAERGEGKVNPNPKVGAIVVKNNKIIGEGYHKYFGGSHAEVYALREAGEKAKGATIYVTLEPCSHYG
KTPPCAESIVKMGISKAIIAMKDPNPLVEGRGIDILKQNGIEVVTGIMEKESKKLNEVFIKYITKKKPFVVLKTASTLDG
KIATRTGESKWITGEDARYKVQQIRNDLSGIMVGIGTIIKDNPLLTTRIEGGRSPRAIIVDSNLRIPLESKILETLNKRA
IYIATTKKHNNFSKKNALENLGAKVLEFEENEEGKVPLNELMQYLGSEGVDSILLEGGSTLNFSALKEGIVDKVMCFIAP
KIMGGQDSKNMIGGNGVESLKDIFNLQNLKFEKIGQDILIEGYVY

Sequences:

>Translated_365_residues
MEDYNFYMEKALKLAERGEGKVNPNPKVGAIVVKNNKIIGEGYHKYFGGSHAEVYALREAGEKAKGATIYVTLEPCSHYG
KTPPCAESIVKMGISKAIIAMKDPNPLVEGRGIDILKQNGIEVVTGIMEKESKKLNEVFIKYITKKKPFVVLKTASTLDG
KIATRTGESKWITGEDARYKVQQIRNDLSGIMVGIGTIIKDNPLLTTRIEGGRSPRAIIVDSNLRIPLESKILETLNKRA
IYIATTKKHNNFSKKNALENLGAKVLEFEENEEGKVPLNELMQYLGSEGVDSILLEGGSTLNFSALKEGIVDKVMCFIAP
KIMGGQDSKNMIGGNGVESLKDIFNLQNLKFEKIGQDILIEGYVY
>Mature_365_residues
MEDYNFYMEKALKLAERGEGKVNPNPKVGAIVVKNNKIIGEGYHKYFGGSHAEVYALREAGEKAKGATIYVTLEPCSHYG
KTPPCAESIVKMGISKAIIAMKDPNPLVEGRGIDILKQNGIEVVTGIMEKESKKLNEVFIKYITKKKPFVVLKTASTLDG
KIATRTGESKWITGEDARYKVQQIRNDLSGIMVGIGTIIKDNPLLTTRIEGGRSPRAIIVDSNLRIPLESKILETLNKRA
IYIATTKKHNNFSKKNALENLGAKVLEFEENEEGKVPLNELMQYLGSEGVDSILLEGGSTLNFSALKEGIVDKVMCFIAP
KIMGGQDSKNMIGGNGVESLKDIFNLQNLKFEKIGQDILIEGYVY

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=374, Percent_Identity=37.7005347593583, Blast_Score=275, Evalue=3e-75,
Organism=Escherichia coli, GI145693172, Length=151, Percent_Identity=31.1258278145695, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40233; Mature: 40233

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDYNFYMEKALKLAERGEGKVNPNPKVGAIVVKNNKIIGEGYHKYFGGSHAEVYALREA
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCCHHHHCCCCCCEEEEEHHC
GEKAKGATIYVTLEPCSHYGKTPPCAESIVKMGISKAIIAMKDPNPLVEGRGIDILKQNG
CCCCCCCEEEEEECCHHCCCCCCHHHHHHHHHCCHHEEEEECCCCCCCCCCCCEEEHHCC
IEVVTGIMEKESKKLNEVFIKYITKKKPFVVLKTASTLDGKIATRTGESKWITGEDARYK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCCCCEECCCCHHHH
VQQIRNDLSGIMVGIGTIIKDNPLLTTRIEGGRSPRAIIVDSNLRIPLESKILETLNKRA
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHCCCE
IYIATTKKHNNFSKKNALENLGAKVLEFEENEEGKVPLNELMQYLGSEGVDSILLEGGST
EEEEEECCCCCCHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCHHHCCCCCE
LNFSALKEGIVDKVMCFIAPKIMGGQDSKNMIGGNGVESLKDIFNLQNLKFEKIGQDILI
EEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHCCCEEEE
EGYVY
EEECC
>Mature Secondary Structure
MEDYNFYMEKALKLAERGEGKVNPNPKVGAIVVKNNKIIGEGYHKYFGGSHAEVYALREA
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCCHHHHCCCCCCEEEEEHHC
GEKAKGATIYVTLEPCSHYGKTPPCAESIVKMGISKAIIAMKDPNPLVEGRGIDILKQNG
CCCCCCCEEEEEECCHHCCCCCCHHHHHHHHHCCHHEEEEECCCCCCCCCCCCEEEHHCC
IEVVTGIMEKESKKLNEVFIKYITKKKPFVVLKTASTLDGKIATRTGESKWITGEDARYK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCCCCEECCCCHHHH
VQQIRNDLSGIMVGIGTIIKDNPLLTTRIEGGRSPRAIIVDSNLRIPLESKILETLNKRA
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHCCCE
IYIATTKKHNNFSKKNALENLGAKVLEFEENEEGKVPLNELMQYLGSEGVDSILLEGGST
EEEEEECCCCCCHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCHHHCCCCCE
LNFSALKEGIVDKVMCFIAPKIMGGQDSKNMIGGNGVESLKDIFNLQNLKFEKIGQDILI
EEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHCCCEEEE
EGYVY
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]