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The map label for this gene is fur [H]

Identifier: 226950239

GI number: 226950239

Start: 3214290

End: 3214757

Strand: Direct

Name: fur [H]

Synonym: CLM_3194

Alternate gene names: 226950239

Gene position: 3214290-3214757 (Clockwise)

Preceding gene: 226950234

Following gene: 226950240

Centisome position: 77.35

GC content: 22.44

Gene sequence:

>468_bases
ATGTCAAGGGAATTAGAATTTTATAAACATATTTTTAACTCTAATAATATTAGGCTTACAACTAGGCGAATTATAATTTT
AAAAATTTTTCTCAACCATAAAAATTATCATTTAACAATAAATGAAATTTATTATTTAGCTAAAAAAATTTCCTCATCAA
TTGGTCTAGCTACTGTTTATAGAACTATTGAAATATTACTAAAACTAGATTTATTAGACCATGTATCACTTGAAGATGGA
GGTAATCGTTATAAATTATTTGTAAATAAGAACATAGATCTCAAAGCTTACAATAAGCATCATCCTCATCTTATTTGCCT
TAATTGTAAAAGAATTATAGATTGTCACTATAATTTTATAGATACTATTAAAACTGAAATAAATAAAAATTGTTTATTTA
AAGTTACTAACTTTGAAATGAAGTTTTATGGATATTGCGAGAAATGTTCTATTAAAAAGGTTAAGTAA

Upstream 100 bases:

>100_bases
TACTATATTTATTGATGCATTATTAGGTTTTTATATGATCAAACCTAGAATTGTCTTGGGTTTATTTATTACTTAACATT
AACATTTAAGGGGAATTTGT

Downstream 100 bases:

>100_bases
TTATTAAATTTAATATTTATTAAAATCATATATTTTTAGCTATAAAATTATATAATTTATATTTATGTAATATATTTACA
ATTTTGTAATAAGAATTTAC

Product: Fur family transcriptional regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MSRELEFYKHIFNSNNIRLTTRRIIILKIFLNHKNYHLTINEIYYLAKKISSSIGLATVYRTIEILLKLDLLDHVSLEDG
GNRYKLFVNKNIDLKAYNKHHPHLICLNCKRIIDCHYNFIDTIKTEINKNCLFKVTNFEMKFYGYCEKCSIKKVK

Sequences:

>Translated_155_residues
MSRELEFYKHIFNSNNIRLTTRRIIILKIFLNHKNYHLTINEIYYLAKKISSSIGLATVYRTIEILLKLDLLDHVSLEDG
GNRYKLFVNKNIDLKAYNKHHPHLICLNCKRIIDCHYNFIDTIKTEINKNCLFKVTNFEMKFYGYCEKCSIKKVK
>Mature_154_residues
SRELEFYKHIFNSNNIRLTTRRIIILKIFLNHKNYHLTINEIYYLAKKISSSIGLATVYRTIEILLKLDLLDHVSLEDGG
NRYKLFVNKNIDLKAYNKHHPHLICLNCKRIIDCHYNFIDTIKTEINKNCLFKVTNFEMKFYGYCEKCSIKKVK

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=138, Percent_Identity=25.3623188405797, Blast_Score=64, Evalue=4e-12,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18522; Mature: 18391

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRELEFYKHIFNSNNIRLTTRRIIILKIFLNHKNYHLTINEIYYLAKKISSSIGLATVY
CCCHHHHHHHHHCCCCEEEEEEEEEEEEEEECCCCEEEEHHHHHHHHHHHCCCCCHHHHH
RTIEILLKLDLLDHVSLEDGGNRYKLFVNKNIDLKAYNKHHPHLICLNCKRIIDCHYNFI
HHHHHHHHHHHHHCCEECCCCCEEEEEEECCCCEEEECCCCCEEEEEECCEEEECCCHHH
DTIKTEINKNCLFKVTNFEMKFYGYCEKCSIKKVK
HHHHHHCCCCEEEEEECEEEEEEEEECCCEEEECC
>Mature Secondary Structure 
SRELEFYKHIFNSNNIRLTTRRIIILKIFLNHKNYHLTINEIYYLAKKISSSIGLATVY
CCHHHHHHHHHCCCCEEEEEEEEEEEEEEECCCCEEEEHHHHHHHHHHHCCCCCHHHHH
RTIEILLKLDLLDHVSLEDGGNRYKLFVNKNIDLKAYNKHHPHLICLNCKRIIDCHYNFI
HHHHHHHHHHHHHCCEECCCCCEEEEEEECCCCEEEECCCCCEEEEEECCEEEECCCHHH
DTIKTEINKNCLFKVTNFEMKFYGYCEKCSIKKVK
HHHHHHCCCCEEEEEECEEEEEEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]