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The map label for this gene is tlpB [H]

Identifier: 226950221

GI number: 226950221

Start: 3188245

End: 3190305

Strand: Reverse

Name: tlpB [H]

Synonym: CLM_3175

Alternate gene names: 226950221

Gene position: 3190305-3188245 (Counterclockwise)

Preceding gene: 226950222

Following gene: 226950220

Centisome position: 76.78

GC content: 33.53

Gene sequence:

>2061_bases
ATGAAAGTTAAAAGCATTGTCCAAAAGAGTATCTTTGCCAAAATGATGTTGTATATTCTTACAGCAGTATTTGTTGTATT
TTTAGCATCTGGTATTTTTTTAGAGTTAAGGATCAAAGATATTGTGACAAAAATGAATTATGAACATCTTTTGACGGAAG
CAAAGGCAGCTTCTAATCAAAACAATGAATTTTTTAAAAAGAATGAAGTATTAGTAAGACAGATGGCAACTAACCAAGAT
ATTATAAAATTAATGAAAGGTGTAAGAACTAGGGATAAAGTTCGAAGTCATCCAGATTATAAAGATGTAATAAACTCTTT
ACAGCAAATAAAAAAGATAGATAAAAATCTTGCTATGGTATGGATTGGTCTACATGATGCTAGTTATTTAGTTACTCAAG
ATCAATGGGACTCTCCAATAGATTGGATTATTAAGGAAAAGCCTTGGTATAAAGAAGCTTTAAAATTAAAACCTGGGGAA
GTACTTTACACAGAACCTTATGTAGATTCTGTAACAGGAAAGATGGTAATTAGTATTATACAGGTAGTATATGATGAGAA
AGGAACTAGTTTAGGCGTAGTGGCTATAGATGTACTACTTGATGAATTACCTAGTATTATGCAAAAATATAAGATTGGTG
AAAGTGGTTTTGTATTCCTAATAAGTAAAAAAGGTGAACTAGCTTATCACCCTGTAAAAGAAATGGTTTTAAAAAATAAT
ATGACAAAAGAAAAAGGTGAAATGGGAGACATAGGAAGAAATATGGTTGCACAAAAGCAGGGCACAGGAATGTATTCTTA
TAAAGATCAGCGCAAATATGTAGGGTATTATCCTATATCCGCTAATGGATGGTCTGTTGCAGCCGTAATAGACCAAAGTG
AATTTAATGAAAAAGTTTCTATGGTAAGAAACCTACTTATTATCTCCTATGCATTAGGAGCAATTATTATTGCAGCGCTA
ATTTATCTAGTAGGGAAAGCTATAGTAAAACCTATTAAAAGTCTTGAAGGATATGGACATAAAATGGCAGACCTAGATTT
TACAGAAGATATATCAAGGGAGCTAGTGGAAAAGGAAGATGAAATAGGATTATTAGCAAAGGCTTTTGAAAATGTTTCTG
TAAATCTAAGAGATTTTGCTAGAAAAACTTTAGAAAGTGCAGAGCAGGTGGCAGCCTCATCAGAGGAGCTTACCTCTACT
AGTCAACAAACTGCAGAAGCAGCAAATGAAATTACTAAAACTATAGAGGAAATGGCTAATTCTGCAGAAGATCAAGCAAG
GCAAACAGAAAGTGGTGCTGTGAATGTAAATGTCCTTGGAGAGACAATTTCAAAAAATCAACAGATGATGGATAGTTTAA
ATAAGGCTATAGAAAAAGTAGATATTTTAAAAAATGAAGGGGTAACTACTTTAAAAGAACTAGTAGAAAAAACTATGGAC
AGTGAAAAGATATCAAAGGAAGTATATAAGGTAATTATTGATAGCAATAAGAGTGCAGAAAAAATTGAAAATGCTAGCGA
GATGATAAAGAGTATAGCATCTCAGACTAATCTCTTAGCTTTAAATGCAGCTATTGAGGCAGCAAGGGCAGGAGAATCAG
GTAAAGGCTTTGCTGTGGTAGCAGACGAAATAAGAAAGTTAGCAGAGCAATCTAATGCTTTCACCGATGAAATTGCTTTG
GTAATTAATGAATTAGCAGTTCAGACAGAAAAAGCAGTTGGGAGTATGGAAATAGTCAGTGATAATACGAAAGAGCAAAC
TAAGAGCGTAGAAAACACAAATAAAAAGTTTGAAGGTATTTCTATAGCTATTGATGAAATGCAGGAAGTAGTACAAACAT
TAAATGGATCAGGAAAGGATATGGAAAGCAAGAAGAATGAAATCATTACAGTAATTGATAATTTATCTGCTATTTCCCAG
GAAACCGCTGCGGGGACAGAAGAGACAGTAGCTGCAGTAGAAGAACAAACCGCTTCTATCTCGGAGTTAGCTAATGCAAG
TGAGTCTTTAGCTAGGTTAGCAGAGGACATGCAGGTTAATATTTCTAGGTTTAGATATTAA

Upstream 100 bases:

>100_bases
TATTTTCTGATATATAATGAAAATAGTAAAAAATAATGGTATGAAATCTAGTAGAAAAGGGGAGGAAACAGGATTTTACC
AATATAGAGGGGGAGAATAA

Downstream 100 bases:

>100_bases
ATATCTTTAAATTAAGTATTACATGGGCTGAATAGTATTTTAAAGAAATATTATTCAGCTTATTTTGAGGATAACAAAGT
CGCATCAACAGCACAAAGGG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MKVKSIVQKSIFAKMMLYILTAVFVVFLASGIFLELRIKDIVTKMNYEHLLTEAKAASNQNNEFFKKNEVLVRQMATNQD
IIKLMKGVRTRDKVRSHPDYKDVINSLQQIKKIDKNLAMVWIGLHDASYLVTQDQWDSPIDWIIKEKPWYKEALKLKPGE
VLYTEPYVDSVTGKMVISIIQVVYDEKGTSLGVVAIDVLLDELPSIMQKYKIGESGFVFLISKKGELAYHPVKEMVLKNN
MTKEKGEMGDIGRNMVAQKQGTGMYSYKDQRKYVGYYPISANGWSVAAVIDQSEFNEKVSMVRNLLIISYALGAIIIAAL
IYLVGKAIVKPIKSLEGYGHKMADLDFTEDISRELVEKEDEIGLLAKAFENVSVNLRDFARKTLESAEQVAASSEELTST
SQQTAEAANEITKTIEEMANSAEDQARQTESGAVNVNVLGETISKNQQMMDSLNKAIEKVDILKNEGVTTLKELVEKTMD
SEKISKEVYKVIIDSNKSAEKIENASEMIKSIASQTNLLALNAAIEAARAGESGKGFAVVADEIRKLAEQSNAFTDEIAL
VINELAVQTEKAVGSMEIVSDNTKEQTKSVENTNKKFEGISIAIDEMQEVVQTLNGSGKDMESKKNEIITVIDNLSAISQ
ETAAGTEETVAAVEEQTASISELANASESLARLAEDMQVNISRFRY

Sequences:

>Translated_686_residues
MKVKSIVQKSIFAKMMLYILTAVFVVFLASGIFLELRIKDIVTKMNYEHLLTEAKAASNQNNEFFKKNEVLVRQMATNQD
IIKLMKGVRTRDKVRSHPDYKDVINSLQQIKKIDKNLAMVWIGLHDASYLVTQDQWDSPIDWIIKEKPWYKEALKLKPGE
VLYTEPYVDSVTGKMVISIIQVVYDEKGTSLGVVAIDVLLDELPSIMQKYKIGESGFVFLISKKGELAYHPVKEMVLKNN
MTKEKGEMGDIGRNMVAQKQGTGMYSYKDQRKYVGYYPISANGWSVAAVIDQSEFNEKVSMVRNLLIISYALGAIIIAAL
IYLVGKAIVKPIKSLEGYGHKMADLDFTEDISRELVEKEDEIGLLAKAFENVSVNLRDFARKTLESAEQVAASSEELTST
SQQTAEAANEITKTIEEMANSAEDQARQTESGAVNVNVLGETISKNQQMMDSLNKAIEKVDILKNEGVTTLKELVEKTMD
SEKISKEVYKVIIDSNKSAEKIENASEMIKSIASQTNLLALNAAIEAARAGESGKGFAVVADEIRKLAEQSNAFTDEIAL
VINELAVQTEKAVGSMEIVSDNTKEQTKSVENTNKKFEGISIAIDEMQEVVQTLNGSGKDMESKKNEIITVIDNLSAISQ
ETAAGTEETVAAVEEQTASISELANASESLARLAEDMQVNISRFRY
>Mature_686_residues
MKVKSIVQKSIFAKMMLYILTAVFVVFLASGIFLELRIKDIVTKMNYEHLLTEAKAASNQNNEFFKKNEVLVRQMATNQD
IIKLMKGVRTRDKVRSHPDYKDVINSLQQIKKIDKNLAMVWIGLHDASYLVTQDQWDSPIDWIIKEKPWYKEALKLKPGE
VLYTEPYVDSVTGKMVISIIQVVYDEKGTSLGVVAIDVLLDELPSIMQKYKIGESGFVFLISKKGELAYHPVKEMVLKNN
MTKEKGEMGDIGRNMVAQKQGTGMYSYKDQRKYVGYYPISANGWSVAAVIDQSEFNEKVSMVRNLLIISYALGAIIIAAL
IYLVGKAIVKPIKSLEGYGHKMADLDFTEDISRELVEKEDEIGLLAKAFENVSVNLRDFARKTLESAEQVAASSEELTST
SQQTAEAANEITKTIEEMANSAEDQARQTESGAVNVNVLGETISKNQQMMDSLNKAIEKVDILKNEGVTTLKELVEKTMD
SEKISKEVYKVIIDSNKSAEKIENASEMIKSIASQTNLLALNAAIEAARAGESGKGFAVVADEIRKLAEQSNAFTDEIAL
VINELAVQTEKAVGSMEIVSDNTKEQTKSVENTNKKFEGISIAIDEMQEVVQTLNGSGKDMESKKNEIITVIDNLSAISQ
ETAAGTEETVAAVEEQTASISELANASESLARLAEDMQVNISRFRY

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=369, Percent_Identity=27.3712737127371, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787690, Length=364, Percent_Identity=26.9230769230769, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI2367378, Length=374, Percent_Identity=24.8663101604278, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788195, Length=315, Percent_Identity=27.3015873015873, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788194, Length=336, Percent_Identity=25.8928571428571, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 76178; Mature: 76178

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKSIVQKSIFAKMMLYILTAVFVVFLASGIFLELRIKDIVTKMNYEHLLTEAKAASNQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCC
NNEFFKKNEVLVRQMATNQDIIKLMKGVRTRDKVRSHPDYKDVINSLQQIKKIDKNLAMV
CCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEE
WIGLHDASYLVTQDQWDSPIDWIIKEKPWYKEALKLKPGEVLYTEPYVDSVTGKMVISII
EEEECCCEEEEECCCCCCCHHHHCCCCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHHH
QVVYDEKGTSLGVVAIDVLLDELPSIMQKYKIGESGFVFLISKKGELAYHPVKEMVLKNN
HHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCC
MTKEKGEMGDIGRNMVAQKQGTGMYSYKDQRKYVGYYPISANGWSVAAVIDQSEFNEKVS
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECHHHHHHHHH
MVRNLLIISYALGAIIIAALIYLVGKAIVKPIKSLEGYGHKMADLDFTEDISRELVEKED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCH
EIGLLAKAFENVSVNLRDFARKTLESAEQVAASSEELTSTSQQTAEAANEITKTIEEMAN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAEDQARQTESGAVNVNVLGETISKNQQMMDSLNKAIEKVDILKNEGVTTLKELVEKTMD
HHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
SEKISKEVYKVIIDSNKSAEKIENASEMIKSIASQTNLLALNAAIEAARAGESGKGFAVV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCHHHH
ADEIRKLAEQSNAFTDEIALVINELAVQTEKAVGSMEIVSDNTKEQTKSVENTNKKFEGI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHCCCHHCCH
SIAIDEMQEVVQTLNGSGKDMESKKNEIITVIDNLSAISQETAAGTEETVAAVEEQTASI
HHHHHHHHHHHHHHCCCCCCCHHHCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SELANASESLARLAEDMQVNISRFRY
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVKSIVQKSIFAKMMLYILTAVFVVFLASGIFLELRIKDIVTKMNYEHLLTEAKAASNQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCC
NNEFFKKNEVLVRQMATNQDIIKLMKGVRTRDKVRSHPDYKDVINSLQQIKKIDKNLAMV
CCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEE
WIGLHDASYLVTQDQWDSPIDWIIKEKPWYKEALKLKPGEVLYTEPYVDSVTGKMVISII
EEEECCCEEEEECCCCCCCHHHHCCCCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHHH
QVVYDEKGTSLGVVAIDVLLDELPSIMQKYKIGESGFVFLISKKGELAYHPVKEMVLKNN
HHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCC
MTKEKGEMGDIGRNMVAQKQGTGMYSYKDQRKYVGYYPISANGWSVAAVIDQSEFNEKVS
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECHHHHHHHHH
MVRNLLIISYALGAIIIAALIYLVGKAIVKPIKSLEGYGHKMADLDFTEDISRELVEKED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCH
EIGLLAKAFENVSVNLRDFARKTLESAEQVAASSEELTSTSQQTAEAANEITKTIEEMAN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAEDQARQTESGAVNVNVLGETISKNQQMMDSLNKAIEKVDILKNEGVTTLKELVEKTMD
HHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
SEKISKEVYKVIIDSNKSAEKIENASEMIKSIASQTNLLALNAAIEAARAGESGKGFAVV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCHHHH
ADEIRKLAEQSNAFTDEIALVINELAVQTEKAVGSMEIVSDNTKEQTKSVENTNKKFEGI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHCCCHHCCH
SIAIDEMQEVVQTLNGSGKDMESKKNEIITVIDNLSAISQETAAGTEETVAAVEEQTASI
HHHHHHHHHHHHHHCCCCCCCHHHCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SELANASESLARLAEDMQVNISRFRY
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]