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The map label for this gene is tlpC [H]

Identifier: 226950215

GI number: 226950215

Start: 3181706

End: 3183400

Strand: Reverse

Name: tlpC [H]

Synonym: CLM_3169

Alternate gene names: 226950215

Gene position: 3183400-3181706 (Counterclockwise)

Preceding gene: 226950216

Following gene: 226950213

Centisome position: 76.61

GC content: 26.84

Gene sequence:

>1695_bases
ATGAAACTTAGAAAAAAGCTTGTACTGTCTTTTTCGATAATACTTTTTTTATTTTCTGTAATTATGTTTTTAACGATTTA
TGTTACAGTTAATAATATGGCAAATAAAAGTTTCTTGAAAAATATAAAAGATAATGCTAATTTAGGATACTCTTATTTAG
ACTCAAAGTACCCTGGTAAATGGAATATAAAAGGAGACAAGCTTTATAAAGGAGAAGAATTAATTAACAATAATTTTTAT
GTGGTGGATAACATAAAAAAAGAAACAGGAAGCTTAGTAACTATATTTATGAAAGATACTAGAATAGCTACAAATGTAAT
TAGTAATGATGGAAAAAGAGCTGTAGGAACTAAGGCTTCAAAAGAGGTATTAGAAAAGGTTTTAGATAAAGGTGAAGAGT
TCCAGGGTACTGCAAAGGTAGCTGGTAAGGAGGTTCTAACCTACTATAAACCTATAAAAGATTCTAATTCTAAAATTATA
GGTATGTGGTTCATAGGGATAGAGAAAGAAACTATTAAAAAAGAAGTTTGGAAAATATTAAGTTATATTCTTTTTATTAT
ATTAATTGTATTGATTATAGGAATAATATTATTTAATTTTATAGGTAATAGCATAGTTAAAAATATATATTCCTTTAATG
AATATCTTAAAAATATGTCTCAGGGAGACTTTAATAAGGAGTTAAATATTAGATATTTAAAACTAAAAGATGAGTTAGGT
CAAATGTTTAATAATTTAGAACATATGCAGATAGCTATAAAGGATATATTAAAGGAAGTAATTACTGATTCAAAAGATTC
TATAAAGTCTAATGAAGATGTATTTATACTTATAAATAAATTATCATCAAATGTAGAGCAAGTTACATCAACTACAGAAG
AAATATCGGCAGCAATGGAGGAAACCGCAGCTTCAGCAGAGGAAGTAAACGCTACAGCTAATGAAATAGAAAAATCTATA
GAAGTAATAACTAATAAAATAGGAGAAGCTTATAAAAAATCCGAGGATATAAGTAATAAAGCAAATAAATTAAAAAAAGA
TGCTGAAAACTCTAAAAAAGAAGCCTTTAATTTGTATAAAAGTAATGAAAAAGAATTAAGTAAAGCTATAGAAAAATCAA
AATCAGTAGAAAAAATTAATGTATTGTCAGAAGCAATACTTAAAATAACAGAGCAAACTAATCTCTTAGCTTTGAATGCT
GCTATTGAAGCTGCTAGAGCAGGGGAAGCAGGAAAAGGATTTTCAGTAGTAGCAGAGGAAATAAGAAAGCTGGCAGAAGA
ATCTAATAATACAGCTAATGAAATTCAAGAGATTACAAAAATTGTAGTTAATGCAGTAGAAAATTTAGCAAATAACTCTA
ATAAGATATTGACATTTATAGATGGAAAAGTAGTAAAAGACTATGAGAATTTAGTTGCTATAGGTGAAATGTATAGTAGT
GATGCAGAATACTATAAAGCTGTATCTGAAAATATAAGTTTCACTACGGAAGAAGTCTTAGCCTCTATGAAAAACGTTAT
AGAATCTATAAATAGTGTAACTATAGCCGCTAATGAAGTAGCGGATGGTACAAGTAATATAGCTAAAAGTGCAAATGATA
TATTAGAAGAAAGCAACAATGTTAAATGTAAATCAGAAGAATCTATGTCTAATTCCGAAAAACTAATAAATTCAATTTCT
AAATTTAAAATATAA

Upstream 100 bases:

>100_bases
TCTTAAAATAAAGCCTATATATTAAAAATATGCTAATTAATTCGATATTATATGTATAAATTACTAGAAAAATAATTTAT
ATATATTTAGGAGGTAGGAT

Downstream 100 bases:

>100_bases
AAATTAAAAAGCTATGCATTTGTAATATATGGTTACAAATATATAGCTTTTTAATTTTTAAAATCAATAAATTTATAAAT
TATTTAGTTTATTCATATTT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MKLRKKLVLSFSIILFLFSVIMFLTIYVTVNNMANKSFLKNIKDNANLGYSYLDSKYPGKWNIKGDKLYKGEELINNNFY
VVDNIKKETGSLVTIFMKDTRIATNVISNDGKRAVGTKASKEVLEKVLDKGEEFQGTAKVAGKEVLTYYKPIKDSNSKII
GMWFIGIEKETIKKEVWKILSYILFIILIVLIIGIILFNFIGNSIVKNIYSFNEYLKNMSQGDFNKELNIRYLKLKDELG
QMFNNLEHMQIAIKDILKEVITDSKDSIKSNEDVFILINKLSSNVEQVTSTTEEISAAMEETAASAEEVNATANEIEKSI
EVITNKIGEAYKKSEDISNKANKLKKDAENSKKEAFNLYKSNEKELSKAIEKSKSVEKINVLSEAILKITEQTNLLALNA
AIEAARAGEAGKGFSVVAEEIRKLAEESNNTANEIQEITKIVVNAVENLANNSNKILTFIDGKVVKDYENLVAIGEMYSS
DAEYYKAVSENISFTTEEVLASMKNVIESINSVTIAANEVADGTSNIAKSANDILEESNNVKCKSEESMSNSEKLINSIS
KFKI

Sequences:

>Translated_564_residues
MKLRKKLVLSFSIILFLFSVIMFLTIYVTVNNMANKSFLKNIKDNANLGYSYLDSKYPGKWNIKGDKLYKGEELINNNFY
VVDNIKKETGSLVTIFMKDTRIATNVISNDGKRAVGTKASKEVLEKVLDKGEEFQGTAKVAGKEVLTYYKPIKDSNSKII
GMWFIGIEKETIKKEVWKILSYILFIILIVLIIGIILFNFIGNSIVKNIYSFNEYLKNMSQGDFNKELNIRYLKLKDELG
QMFNNLEHMQIAIKDILKEVITDSKDSIKSNEDVFILINKLSSNVEQVTSTTEEISAAMEETAASAEEVNATANEIEKSI
EVITNKIGEAYKKSEDISNKANKLKKDAENSKKEAFNLYKSNEKELSKAIEKSKSVEKINVLSEAILKITEQTNLLALNA
AIEAARAGEAGKGFSVVAEEIRKLAEESNNTANEIQEITKIVVNAVENLANNSNKILTFIDGKVVKDYENLVAIGEMYSS
DAEYYKAVSENISFTTEEVLASMKNVIESINSVTIAANEVADGTSNIAKSANDILEESNNVKCKSEESMSNSEKLINSIS
KFKI
>Mature_564_residues
MKLRKKLVLSFSIILFLFSVIMFLTIYVTVNNMANKSFLKNIKDNANLGYSYLDSKYPGKWNIKGDKLYKGEELINNNFY
VVDNIKKETGSLVTIFMKDTRIATNVISNDGKRAVGTKASKEVLEKVLDKGEEFQGTAKVAGKEVLTYYKPIKDSNSKII
GMWFIGIEKETIKKEVWKILSYILFIILIVLIIGIILFNFIGNSIVKNIYSFNEYLKNMSQGDFNKELNIRYLKLKDELG
QMFNNLEHMQIAIKDILKEVITDSKDSIKSNEDVFILINKLSSNVEQVTSTTEEISAAMEETAASAEEVNATANEIEKSI
EVITNKIGEAYKKSEDISNKANKLKKDAENSKKEAFNLYKSNEKELSKAIEKSKSVEKINVLSEAILKITEQTNLLALNA
AIEAARAGEAGKGFSVVAEEIRKLAEESNNTANEIQEITKIVVNAVENLANNSNKILTFIDGKVVKDYENLVAIGEMYSS
DAEYYKAVSENISFTTEEVLASMKNVIESINSVTIAANEVADGTSNIAKSANDILEESNNVKCKSEESMSNSEKLINSIS
KFKI

Specific function: Mediates Taxis To The Sugars Ribose And Galactose VIa An Interaction With The Periplasmic Ribose- Or Galactose-Binding Proteins. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of Attractants And Repellents In The Environment, Trans

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=257, Percent_Identity=29.1828793774319, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1789453, Length=373, Percent_Identity=23.5924932975871, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI2367378, Length=277, Percent_Identity=28.158844765343, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788195, Length=233, Percent_Identity=29.6137339055794, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1788194, Length=314, Percent_Identity=27.3885350318471, Blast_Score=90, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 63072; Mature: 63072

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRKKLVLSFSIILFLFSVIMFLTIYVTVNNMANKSFLKNIKDNANLGYSYLDSKYPGK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCC
WNIKGDKLYKGEELINNNFYVVDNIKKETGSLVTIFMKDTRIATNVISNDGKRAVGTKAS
CCCCCCCEECCHHHHCCCCEEEECCCCCCCCEEEEEEECCHHHHHHHCCCCCCCCCCHHH
KEVLEKVLDKGEEFQGTAKVAGKEVLTYYKPIKDSNSKIIGMWFIGIEKETIKKEVWKIL
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHH
SYILFIILIVLIIGIILFNFIGNSIVKNIYSFNEYLKNMSQGDFNKELNIRYLKLKDELG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHH
QMFNNLEHMQIAIKDILKEVITDSKDSIKSNEDVFILINKLSSNVEQVTSTTEEISAAME
HHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
ETAASAEEVNATANEIEKSIEVITNKIGEAYKKSEDISNKANKLKKDAENSKKEAFNLYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SNEKELSKAIEKSKSVEKINVLSEAILKITEQTNLLALNAAIEAARAGEAGKGFSVVAEE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCHHHHHHH
IRKLAEESNNTANEIQEITKIVVNAVENLANNSNKILTFIDGKVVKDYENLVAIGEMYSS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHC
DAEYYKAVSENISFTTEEVLASMKNVIESINSVTIAANEVADGTSNIAKSANDILEESNN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCEEEEHHHHCCCHHHHHHHHHHHHHCCCC
VKCKSEESMSNSEKLINSISKFKI
CCCCCHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLRKKLVLSFSIILFLFSVIMFLTIYVTVNNMANKSFLKNIKDNANLGYSYLDSKYPGK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCC
WNIKGDKLYKGEELINNNFYVVDNIKKETGSLVTIFMKDTRIATNVISNDGKRAVGTKAS
CCCCCCCEECCHHHHCCCCEEEECCCCCCCCEEEEEEECCHHHHHHHCCCCCCCCCCHHH
KEVLEKVLDKGEEFQGTAKVAGKEVLTYYKPIKDSNSKIIGMWFIGIEKETIKKEVWKIL
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHH
SYILFIILIVLIIGIILFNFIGNSIVKNIYSFNEYLKNMSQGDFNKELNIRYLKLKDELG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHH
QMFNNLEHMQIAIKDILKEVITDSKDSIKSNEDVFILINKLSSNVEQVTSTTEEISAAME
HHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
ETAASAEEVNATANEIEKSIEVITNKIGEAYKKSEDISNKANKLKKDAENSKKEAFNLYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SNEKELSKAIEKSKSVEKINVLSEAILKITEQTNLLALNAAIEAARAGEAGKGFSVVAEE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCHHHHHHH
IRKLAEESNNTANEIQEITKIVVNAVENLANNSNKILTFIDGKVVKDYENLVAIGEMYSS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHC
DAEYYKAVSENISFTTEEVLASMKNVIESINSVTIAANEVADGTSNIAKSANDILEESNN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCEEEEHHHHCCCHHHHHHHHHHHHHCCCC
VKCKSEESMSNSEKLINSISKFKI
CCCCCHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377 [H]