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The map label for this gene is yclF [H]

Identifier: 226949537

GI number: 226949537

Start: 2548973

End: 2550370

Strand: Direct

Name: yclF [H]

Synonym: CLM_2473

Alternate gene names: 226949537

Gene position: 2548973-2550370 (Clockwise)

Preceding gene: 226949536

Following gene: 226949542

Centisome position: 61.34

GC content: 36.19

Gene sequence:

>1398_bases
ATGTCACAAGAAAAACAAAAACATCCTATAGGCCTTTCACTGGTAAATATCTCTATAGCTCTCCAAAGTTATGCGGGATA
TGCAGTATCATCTGTATTAATATTATTCTTTACAGCTGATATCAACCGAAATGGCTTAGGCTTAAGCGTACCAAAAGCGG
CTTCTATCATCGGCTTATACCAAGGTGTCAACTACATGGGATCTCTTGTTGGGGGATATATCACCGATAAATGGCTAGGA
ATTCAGAAATCACTGATGTTAGGTTCTTTCTTAACTGCATGTGGATATATGGTACTGTTTTTTGCAAAGCCAAATATCGG
GAGTATCTGGTTAGGGCTTATTGTCTTAATTATAGCAGGTGCATTTTTCAAGGGACAGATTAGTACACTTGTGGGCTCAC
TTTATCGGAAAAATGAATTATCTAAAAAAGATGCCGCCTACAGCATATTCTATATGTTTATAAACATTGGTTCTTTCTTT
GGACCTATAATTGCAGGGTTAATCTCTGATAAATGGTTCGCTAAAGTAGCCGCTGATGGAGAAATTGCAGCCTATGGTTA
TAAATATATTTTTCTTATGTGTGCTATTGTGATGATAATTGTATGTGCTTTGATTTTGATTTTATCTCCTAAATGGTTGG
GGGATGTTGGAAAATACCCAGCATCAAAAACTGAAGCTAAAAAAGCTTCCTCAAAATCCGAAGAAAAAGTTACAAACAAA
CCTTTGACACATACAGAAAAGAACCGTATTAAAGCGATGCTTGTCATGTTTCTATTTGTGATTATATTCTGGTCTGCATG
GTACCAAACTGCTACGTCTTTCTCTTTGCTTGCGGATAAACTAGTAAACAGAAAATTGGGTGGATTTACAATGCCTGTAC
CTTGGCTTACTTCTGTTAATGCCATCTTCTGTGTAGCATTTTCCCCAGTACTAGCAAATATCTGGGTAAAACTTGGAAAT
AGCAAAAATGGTGATTTATCTGTTCCTACTAAAATGGGACTTGGATTGATTTTGGCAGGAGCTTCCTTTATTACCTTGAT
TTTAGGTATTTCCACATTAGGCGGTGTCACAGACGGAAGCAGACAAATGAATATACTTTTTATCATTGTTGCTTACTTTT
TATTAACATTGGGTGAACTTTGCCTGTCTCCAATAGGAATGGCTATGTTCAATAAACTAGCTCCTGCTAAATTTGGCTCA
CTAGCAATGGGAGCATGGTACTTAAGTTTCTTTTTTTCAAACTTGATTTCAGGGAAACTGGCAGGATTCACAGATACCAT
GGGATATACAGAAATCTTTGGTTTTATAGCTGGTGTTGTAATCATATTTGGTTTAATCCTGATTTTATTAAGAAAGGGCT
TATTAAGGCTTATGTCTTTGGACGAATTTAATAAGTAA

Upstream 100 bases:

>100_bases
TAAACTTTCACCATACCTTACTCAAGAAGAAAAAGACTGGTTAAAAGAATATACCAGAAAAATTTCATAATTAAGTCCAA
TTGAAAGAAGGTATGTAACA

Downstream 100 bases:

>100_bases
ATAAGCACAAACAGCATATTACAAGTACAATAATACAAAAAAGACTATAATACTATTAACTATAGCACTATAGTCTTTTC
CTAACTTAAATATTCCTTCA

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSQEKQKHPIGLSLVNISIALQSYAGYAVSSVLILFFTADINRNGLGLSVPKAASIIGLYQGVNYMGSLVGGYITDKWLG
IQKSLMLGSFLTACGYMVLFFAKPNIGSIWLGLIVLIIAGAFFKGQISTLVGSLYRKNELSKKDAAYSIFYMFINIGSFF
GPIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCAIVMIIVCALILILSPKWLGDVGKYPASKTEAKKASSKSEEKVTNK
PLTHTEKNRIKAMLVMFLFVIIFWSAWYQTATSFSLLADKLVNRKLGGFTMPVPWLTSVNAIFCVAFSPVLANIWVKLGN
SKNGDLSVPTKMGLGLILAGASFITLILGISTLGGVTDGSRQMNILFIIVAYFLLTLGELCLSPIGMAMFNKLAPAKFGS
LAMGAWYLSFFFSNLISGKLAGFTDTMGYTEIFGFIAGVVIIFGLILILLRKGLLRLMSLDEFNK

Sequences:

>Translated_465_residues
MSQEKQKHPIGLSLVNISIALQSYAGYAVSSVLILFFTADINRNGLGLSVPKAASIIGLYQGVNYMGSLVGGYITDKWLG
IQKSLMLGSFLTACGYMVLFFAKPNIGSIWLGLIVLIIAGAFFKGQISTLVGSLYRKNELSKKDAAYSIFYMFINIGSFF
GPIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCAIVMIIVCALILILSPKWLGDVGKYPASKTEAKKASSKSEEKVTNK
PLTHTEKNRIKAMLVMFLFVIIFWSAWYQTATSFSLLADKLVNRKLGGFTMPVPWLTSVNAIFCVAFSPVLANIWVKLGN
SKNGDLSVPTKMGLGLILAGASFITLILGISTLGGVTDGSRQMNILFIIVAYFLLTLGELCLSPIGMAMFNKLAPAKFGS
LAMGAWYLSFFFSNLISGKLAGFTDTMGYTEIFGFIAGVVIIFGLILILLRKGLLRLMSLDEFNK
>Mature_464_residues
SQEKQKHPIGLSLVNISIALQSYAGYAVSSVLILFFTADINRNGLGLSVPKAASIIGLYQGVNYMGSLVGGYITDKWLGI
QKSLMLGSFLTACGYMVLFFAKPNIGSIWLGLIVLIIAGAFFKGQISTLVGSLYRKNELSKKDAAYSIFYMFINIGSFFG
PIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCAIVMIIVCALILILSPKWLGDVGKYPASKTEAKKASSKSEEKVTNKP
LTHTEKNRIKAMLVMFLFVIIFWSAWYQTATSFSLLADKLVNRKLGGFTMPVPWLTSVNAIFCVAFSPVLANIWVKLGNS
KNGDLSVPTKMGLGLILAGASFITLILGISTLGGVTDGSRQMNILFIIVAYFLLTLGELCLSPIGMAMFNKLAPAKFGSL
AMGAWYLSFFFSNLISGKLAGFTDTMGYTEIFGFIAGVVIIFGLILILLRKGLLRLMSLDEFNK

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Escherichia coli, GI1789911, Length=490, Percent_Identity=25.7142857142857, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787922, Length=458, Percent_Identity=24.0174672489083, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1790572, Length=400, Percent_Identity=24, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1786927, Length=496, Percent_Identity=24.3951612903226, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 50577; Mature: 50446

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS50850 MFS ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQEKQKHPIGLSLVNISIALQSYAGYAVSSVLILFFTADINRNGLGLSVPKAASIIGLY
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH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CCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]