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The map label for this gene is yusZ [H]

Identifier: 226949508

GI number: 226949508

Start: 2525379

End: 2526176

Strand: Direct

Name: yusZ [H]

Synonym: CLM_2443

Alternate gene names: 226949508

Gene position: 2525379-2526176 (Clockwise)

Preceding gene: 226949505

Following gene: 226949513

Centisome position: 60.78

GC content: 27.32

Gene sequence:

>798_bases
ATGAGTAAAATATTAATTACAGGTGCAGGTTCTGGTCTTGGGAAGGCTTCTTCTATTGCTTTAGCTAGAAGAGGACATAA
AGTTTATGCAACTACTCATAGAAAATCTCAAGCAGAAAATCTAAAAGACATAGCCTTAAAAGAAAATATAAGTAAAAATA
TTGAAAGCTTTAAGTTAGATATAACTTTAAAAGAAGATAGAGATATTGTAAAAAATTTAGATATAGATGCATTGATTAAT
AATGCTGCTATAGGCGACTCTGGTTCTGCATCAGAAGTTTCAATTAATAAATATAGAAATGTATTTGAAACCAATGTATT
TTCTGCTTTAGAGCTTACCCAAATTGTATTTAATAACATGATTAAAAAAAATGAAGGAAGAATTATTTTTTTATCTTCCT
TATCTGGTAGAATTACAATACCTTTTTTATCACCTTATACATCTAGCAAATTTGCCTTAGAAGCAATAGCATCTTCTCTA
AAAGAAGAAATAAAAGAACTTCATAACTGTAACATTAATATAATTTTGATTGAGCCTGGTGCTTATAAAACTGGCTTTAA
CCAAAGAAATATTTATAAGCAATTTGTATGGATGAAGGAAAAATCCTATTTTAAAGATAAATTAGTAAAATTAAAAAAGA
AGCAATACAGCTATTTTGAATTAATGGAACATAAATCCTTTAATTCTATAGTAAATCAGTATATACATGCTATAGAAGAT
GAATCTCCTAAATTCAGATACAAAGCTCCTTTAGCTCAAAGTGCTTTTACCCAAGGACAAAGAATATTAGGTAAATAA

Upstream 100 bases:

>100_bases
TAATAATCTATTGAAATATGTTAAATGTTTTACCTAACTAGGATAATCTAGCCTCAATTGTACAATATAAATAATATAAA
AGTTTTATGGAAGTGATATT

Downstream 100 bases:

>100_bases
GATGTAACCCAGATTAAACATCTTCTGGTTTTATATTTATATTATATTATTGTAATATCATTCTATATTTTTCTTAAAAC
TATTGTTAAATCTAGTAAAA

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: ORFA [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSKILITGAGSGLGKASSIALARRGHKVYATTHRKSQAENLKDIALKENISKNIESFKLDITLKEDRDIVKNLDIDALIN
NAAIGDSGSASEVSINKYRNVFETNVFSALELTQIVFNNMIKKNEGRIIFLSSLSGRITIPFLSPYTSSKFALEAIASSL
KEEIKELHNCNINIILIEPGAYKTGFNQRNIYKQFVWMKEKSYFKDKLVKLKKKQYSYFELMEHKSFNSIVNQYIHAIED
ESPKFRYKAPLAQSAFTQGQRILGK

Sequences:

>Translated_265_residues
MSKILITGAGSGLGKASSIALARRGHKVYATTHRKSQAENLKDIALKENISKNIESFKLDITLKEDRDIVKNLDIDALIN
NAAIGDSGSASEVSINKYRNVFETNVFSALELTQIVFNNMIKKNEGRIIFLSSLSGRITIPFLSPYTSSKFALEAIASSL
KEEIKELHNCNINIILIEPGAYKTGFNQRNIYKQFVWMKEKSYFKDKLVKLKKKQYSYFELMEHKSFNSIVNQYIHAIED
ESPKFRYKAPLAQSAFTQGQRILGK
>Mature_264_residues
SKILITGAGSGLGKASSIALARRGHKVYATTHRKSQAENLKDIALKENISKNIESFKLDITLKEDRDIVKNLDIDALINN
AAIGDSGSASEVSINKYRNVFETNVFSALELTQIVFNNMIKKNEGRIIFLSSLSGRITIPFLSPYTSSKFALEAIASSLK
EEIKELHNCNINIILIEPGAYKTGFNQRNIYKQFVWMKEKSYFKDKLVKLKKKQYSYFELMEHKSFNSIVNQYIHAIEDE
SPKFRYKAPLAQSAFTQGQRILGK

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=268, Percent_Identity=27.6119402985075, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI22507405, Length=265, Percent_Identity=26.4150943396226, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI150247226, Length=262, Percent_Identity=25.9541984732824, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI20149619, Length=188, Percent_Identity=29.2553191489362, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI40548397, Length=267, Percent_Identity=28.8389513108614, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI214010158, Length=267, Percent_Identity=28.8389513108614, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI214010156, Length=267, Percent_Identity=28.8389513108614, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI22758144, Length=267, Percent_Identity=28.8389513108614, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI223718074, Length=194, Percent_Identity=27.319587628866, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI19743808, Length=265, Percent_Identity=25.2830188679245, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI142976729, Length=190, Percent_Identity=26.8421052631579, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI44680136, Length=271, Percent_Identity=24.7232472324723, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI44680133, Length=271, Percent_Identity=24.7232472324723, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI17738292, Length=271, Percent_Identity=24.7232472324723, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI50726952, Length=261, Percent_Identity=25.6704980842912, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI119392083, Length=268, Percent_Identity=25.7462686567164, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI157739938, Length=174, Percent_Identity=27.0114942528736, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI7706318, Length=169, Percent_Identity=27.2189349112426, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI210032110, Length=196, Percent_Identity=27.0408163265306, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI109715829, Length=194, Percent_Identity=25.7731958762887, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4503817, Length=198, Percent_Identity=22.2222222222222, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI32455239, Length=189, Percent_Identity=28.042328042328, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI5031765, Length=189, Percent_Identity=28.042328042328, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1786701, Length=260, Percent_Identity=29.2307692307692, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788459, Length=192, Percent_Identity=29.6875, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787526, Length=194, Percent_Identity=26.2886597938144, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787820, Length=187, Percent_Identity=25.668449197861, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1787335, Length=189, Percent_Identity=26.984126984127, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193210355, Length=259, Percent_Identity=29.3436293436293, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71997402, Length=193, Percent_Identity=32.6424870466321, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17570069, Length=193, Percent_Identity=31.0880829015544, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI115534660, Length=264, Percent_Identity=25.7575757575758, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17557780, Length=264, Percent_Identity=23.8636363636364, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32563809, Length=268, Percent_Identity=23.8805970149254, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17507613, Length=268, Percent_Identity=23.8805970149254, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17567345, Length=243, Percent_Identity=28.3950617283951, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=211, Percent_Identity=30.8056872037915, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=195, Percent_Identity=31.7948717948718, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=211, Percent_Identity=35.5450236966825, Blast_Score=96, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6322067, Length=179, Percent_Identity=30.1675977653631, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358495, Length=189, Percent_Identity=30.1587301587302, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24580925, Length=197, Percent_Identity=31.4720812182741, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24640492, Length=200, Percent_Identity=27, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281364494, Length=195, Percent_Identity=28.7179487179487, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI281364892, Length=173, Percent_Identity=28.9017341040462, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21355631, Length=174, Percent_Identity=26.4367816091954, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28571526, Length=208, Percent_Identity=26.4423076923077, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 29999; Mature: 29868

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKILITGAGSGLGKASSIALARRGHKVYATTHRKSQAENLKDIALKENISKNIESFKLD
CCEEEEEECCCCCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHEEEE
ITLKEDRDIVKNLDIDALINNAAIGDSGSASEVSINKYRNVFETNVFSALELTQIVFNNM
EEECCCHHHHHCCCHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
IKKNEGRIIFLSSLSGRITIPFLSPYTSSKFALEAIASSLKEEIKELHNCNINIILIEPG
HHCCCCCEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
AYKTGFNQRNIYKQFVWMKEKSYFKDKLVKLKKKQYSYFELMEHKSFNSIVNQYIHAIED
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
ESPKFRYKAPLAQSAFTQGQRILGK
CCCCEEEECCCHHHHHHCCHHHHCC
>Mature Secondary Structure 
SKILITGAGSGLGKASSIALARRGHKVYATTHRKSQAENLKDIALKENISKNIESFKLD
CEEEEEECCCCCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHEEEE
ITLKEDRDIVKNLDIDALINNAAIGDSGSASEVSINKYRNVFETNVFSALELTQIVFNNM
EEECCCHHHHHCCCHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
IKKNEGRIIFLSSLSGRITIPFLSPYTSSKFALEAIASSLKEEIKELHNCNINIILIEPG
HHCCCCCEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
AYKTGFNQRNIYKQFVWMKEKSYFKDKLVKLKKKQYSYFELMEHKSFNSIVNQYIHAIED
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
ESPKFRYKAPLAQSAFTQGQRILGK
CCCCEEEECCCHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377; 8396117 [H]