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The map label for this gene is steT [H]

Identifier: 226949458

GI number: 226949458

Start: 2467338

End: 2468660

Strand: Direct

Name: steT [H]

Synonym: CLM_2391

Alternate gene names: 226949458

Gene position: 2467338-2468660 (Clockwise)

Preceding gene: 226949457

Following gene: 226949469

Centisome position: 59.38

GC content: 30.84

Gene sequence:

>1323_bases
ATGTTAGAAAAGAAATATGGGCTTTGGACAACAGTTTCCATGGTTATTGGTATAGTAATCGGATCTGGTGTATTTTTTAA
AGCTGATAATATTCTTATGGCTTCAGGTGGAAATGTAAAAACAGCCTTACTTGCATGGTTAGTAGGAGCAATTTCTATGA
TTTTTGGAGCCTTAGTTTTTGCAGAGTGCGCTAATAGATTTGAAAGATCTAACGGGATAGTTGACTATGCCGAGGGTATG
CTTTCAGAAAAATTTGCTTATTTAATAGGATGGTTTAATGGAATTATTTATTATCCAGCAATAGCTGCGGTACTAGCTTG
GGCAGCTGGTAATTATACTGCTATTTTATTTAATAAAGATGGTAATTTTGTATGGATTATGGCCGCAATATATATGATAG
GTATATATATTTTGAACTATATTTCACCTATACTATCAGGGAAATTCCAAATTGCTTCAACAGCAATCAAACTAGTTCCT
TTAATGCTCATCGCTATATTGGGTACATTTCAAGGACTTAATAATGGAATTTTAATTGAAAATTTTTCTAAAGTATCTAC
TATAGGTGACAGTGGAAGTGGTTTTGCAGCCGCTGTATTAGGAGCAGCCTTTGCATATGAAGGATGGATTATTGCAACAA
CAATTAATGGTGAAATTAAAGATGCCAAAAATACTCTTCCTAAAGCTCTTGTATTTGGCTCATTAGTAATAGTTATTATA
TATATTTTATATTTTCTGGGTATTGTAGGAATGATACCTACTGAAACTATTTTAAAACAAGGAGACAATACTGTAAATGT
GGCTGCTAGGACTGTATTTGGAAACTTTGGCGCATCTATTCTTACAACATTTATAATAGTATCCTGTTTAGGTACTCTTA
ATGGACTTATACTTGGAGGTTCTCGTTCCTTTTATTCTTTGGCTATTCGTGGTCAAGGTATTAAACCAGAGGCTTTTTCT
AAATTAGATAGTAAAACTAATATACCTACTAATTCTACTATAGCAAACTTTATTTTAATTTGCATTTATTTAGTGGTTTG
GTATATGAATTTTAAAGGAATATTTCCTAATAAAATGTTTGTAGATATTTCAGAATTACCAATAGCTTTAATATATGGGA
TTTATATTATTATCTATATTGCATATATGATGAAAATGAAGGACTTATCATTTATAAAAAGATTTGTTATTCCTTCCCTT
GCTCTTATGGGAGCTTTAATTGTTGTATACGGTGGACTTTCTAAACCTTCTGTAATAATTGATTTAGGTATTTCTGTTTT
TGTATTCCTTTCCGGTTTACTATTTTATAATAAGAAGAAATAA

Upstream 100 bases:

>100_bases
TCACAGAATAGATACATTTCATTGATTTAGTCTGAACTACTTCATATAGTTATTAAGTTTTTTAATTATTAGGAAATACT
AAAGAAAAGGAGAGGTGTGT

Downstream 100 bases:

>100_bases
ATTAAATAGAGTGTGTCAAAATAGACTTAATTTTATTTTGACACACAACCTTACTTTAAACTGCATCTTACTTATTATAA
TTACTTTTTAATAATAAGAA

Product: amino acid permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MLEKKYGLWTTVSMVIGIVIGSGVFFKADNILMASGGNVKTALLAWLVGAISMIFGALVFAECANRFERSNGIVDYAEGM
LSEKFAYLIGWFNGIIYYPAIAAVLAWAAGNYTAILFNKDGNFVWIMAAIYMIGIYILNYISPILSGKFQIASTAIKLVP
LMLIAILGTFQGLNNGILIENFSKVSTIGDSGSGFAAAVLGAAFAYEGWIIATTINGEIKDAKNTLPKALVFGSLVIVII
YILYFLGIVGMIPTETILKQGDNTVNVAARTVFGNFGASILTTFIIVSCLGTLNGLILGGSRSFYSLAIRGQGIKPEAFS
KLDSKTNIPTNSTIANFILICIYLVVWYMNFKGIFPNKMFVDISELPIALIYGIYIIIYIAYMMKMKDLSFIKRFVIPSL
ALMGALIVVYGGLSKPSVIIDLGISVFVFLSGLLFYNKKK

Sequences:

>Translated_440_residues
MLEKKYGLWTTVSMVIGIVIGSGVFFKADNILMASGGNVKTALLAWLVGAISMIFGALVFAECANRFERSNGIVDYAEGM
LSEKFAYLIGWFNGIIYYPAIAAVLAWAAGNYTAILFNKDGNFVWIMAAIYMIGIYILNYISPILSGKFQIASTAIKLVP
LMLIAILGTFQGLNNGILIENFSKVSTIGDSGSGFAAAVLGAAFAYEGWIIATTINGEIKDAKNTLPKALVFGSLVIVII
YILYFLGIVGMIPTETILKQGDNTVNVAARTVFGNFGASILTTFIIVSCLGTLNGLILGGSRSFYSLAIRGQGIKPEAFS
KLDSKTNIPTNSTIANFILICIYLVVWYMNFKGIFPNKMFVDISELPIALIYGIYIIIYIAYMMKMKDLSFIKRFVIPSL
ALMGALIVVYGGLSKPSVIIDLGISVFVFLSGLLFYNKKK
>Mature_440_residues
MLEKKYGLWTTVSMVIGIVIGSGVFFKADNILMASGGNVKTALLAWLVGAISMIFGALVFAECANRFERSNGIVDYAEGM
LSEKFAYLIGWFNGIIYYPAIAAVLAWAAGNYTAILFNKDGNFVWIMAAIYMIGIYILNYISPILSGKFQIASTAIKLVP
LMLIAILGTFQGLNNGILIENFSKVSTIGDSGSGFAAAVLGAAFAYEGWIIATTINGEIKDAKNTLPKALVFGSLVIVII
YILYFLGIVGMIPTETILKQGDNTVNVAARTVFGNFGASILTTFIIVSCLGTLNGLILGGSRSFYSLAIRGQGIKPEAFS
KLDSKTNIPTNSTIANFILICIYLVVWYMNFKGIFPNKMFVDISELPIALIYGIYIIIYIAYMMKMKDLSFIKRFVIPSL
ALMGALIVVYGGLSKPSVIIDLGISVFVFLSGLLFYNKKK

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI7657683, Length=318, Percent_Identity=26.1006289308176, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI187423910, Length=447, Percent_Identity=25.0559284116331, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI7657591, Length=447, Percent_Identity=25.0559284116331, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI186910308, Length=355, Percent_Identity=26.1971830985915, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI186910306, Length=355, Percent_Identity=26.1971830985915, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI186910304, Length=355, Percent_Identity=26.1971830985915, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI33286428, Length=349, Percent_Identity=25.214899713467, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI115648063, Length=355, Percent_Identity=24.5070422535211, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI115648022, Length=355, Percent_Identity=24.5070422535211, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI2367353, Length=367, Percent_Identity=24.7956403269755, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082250, Length=343, Percent_Identity=26.2390670553936, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788480, Length=340, Percent_Identity=25, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71990446, Length=372, Percent_Identity=27.4193548387097, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71982612, Length=350, Percent_Identity=27.1428571428571, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71982608, Length=350, Percent_Identity=27.1428571428571, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17540018, Length=365, Percent_Identity=27.9452054794521, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71995388, Length=361, Percent_Identity=29.0858725761773, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17568033, Length=345, Percent_Identity=26.6666666666667, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71995382, Length=361, Percent_Identity=29.0858725761773, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71993915, Length=363, Percent_Identity=28.099173553719, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193208714, Length=345, Percent_Identity=24.0579710144928, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI32566695, Length=346, Percent_Identity=23.9884393063584, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24651635, Length=353, Percent_Identity=25.2124645892351, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24651633, Length=353, Percent_Identity=25.2124645892351, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI45550968, Length=350, Percent_Identity=27.7142857142857, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI19921172, Length=350, Percent_Identity=27.7142857142857, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI221331183, Length=338, Percent_Identity=24.2603550295858, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17647653, Length=338, Percent_Identity=24.2603550295858, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24664379, Length=338, Percent_Identity=24.2603550295858, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21357367, Length=363, Percent_Identity=25.3443526170799, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641995, Length=324, Percent_Identity=24.0740740740741, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641993, Length=324, Percent_Identity=24.0740740740741, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 47754; Mature: 47754

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKKYGLWTTVSMVIGIVIGSGVFFKADNILMASGGNVKTALLAWLVGAISMIFGALVF
CCCCCCCHHHHHHHHHHHHHCCCEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
AECANRFERSNGIVDYAEGMLSEKFAYLIGWFNGIIYYPAIAAVLAWAAGNYTAILFNKD
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GNFVWIMAAIYMIGIYILNYISPILSGKFQIASTAIKLVPLMLIAILGTFQGLNNGILIE
CCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
NFSKVSTIGDSGSGFAAAVLGAAFAYEGWIIATTINGEIKDAKNTLPKALVFGSLVIVII
CCHHHHCCCCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
YILYFLGIVGMIPTETILKQGDNTVNVAARTVFGNFGASILTTFIIVSCLGTLNGLILGG
HHHHHHHHHHHCCHHHHHHCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEECC
SRSFYSLAIRGQGIKPEAFSKLDSKTNIPTNSTIANFILICIYLVVWYMNFKGIFPNKMF
CCCEEEEEEECCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
VDISELPIALIYGIYIIIYIAYMMKMKDLSFIKRFVIPSLALMGALIVVYGGLSKPSVII
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
DLGISVFVFLSGLLFYNKKK
EHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLEKKYGLWTTVSMVIGIVIGSGVFFKADNILMASGGNVKTALLAWLVGAISMIFGALVF
CCCCCCCHHHHHHHHHHHHHCCCEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
AECANRFERSNGIVDYAEGMLSEKFAYLIGWFNGIIYYPAIAAVLAWAAGNYTAILFNKD
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GNFVWIMAAIYMIGIYILNYISPILSGKFQIASTAIKLVPLMLIAILGTFQGLNNGILIE
CCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
NFSKVSTIGDSGSGFAAAVLGAAFAYEGWIIATTINGEIKDAKNTLPKALVFGSLVIVII
CCHHHHCCCCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
YILYFLGIVGMIPTETILKQGDNTVNVAARTVFGNFGASILTTFIIVSCLGTLNGLILGG
HHHHHHHHHHHCCHHHHHHCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEECC
SRSFYSLAIRGQGIKPEAFSKLDSKTNIPTNSTIANFILICIYLVVWYMNFKGIFPNKMF
CCCEEEEEEECCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
VDISELPIALIYGIYIIIYIAYMMKMKDLSFIKRFVIPSLALMGALIVVYGGLSKPSVII
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
DLGISVFVFLSGLLFYNKKK
EHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]