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The map label for this gene is galE [C]

Identifier: 226949379

GI number: 226949379

Start: 2374676

End: 2375599

Strand: Reverse

Name: galE [C]

Synonym: CLM_2304

Alternate gene names: 226949379

Gene position: 2375599-2374676 (Counterclockwise)

Preceding gene: 226949384

Following gene: 226949378

Centisome position: 57.17

GC content: 27.81

Gene sequence:

>924_bases
ATGAAGGTATTAGTTAGTGGCGGTGCAGGATTTATAGGATCTAATTTAGTAGATAAACTTATAAATCTAGGACACAATGT
ATGTATAATAGATAATTTATCTACTGGAAATATAAATAATGTAAATAAAAAAGCTCAATTATATATAAATGATATTTTGG
ATCCTAATGTATCAAAAATATTTGAAAAGGAAAAGTTTGATATAGTCTATCATCTAGCAGCACAGATAGATGTGCAAAAA
TCTATAACGAATCCTATATTTGATTCTGATGTAAATGTATGTGGTACTATAAATATAATAAATAATTGTGTTAACTATAA
TGTTAAAAAAATAGTATATTCTTCTTCAGCAGCTGTCTATGGTCATCCCGGATACTTACCTATAGATGAAAAACATGGAA
TAAGGCCCATATCTTATTATGGATTATCTAAATATACTGCTGAAGAATATATAAGATTATTTAGTAATTTAAATAATTTA
GACTTCACCATACTTAGATATGCAAATGTATACGGAATAAGGCAAGATCCAAAAGGGGAAGGTGGCGTAATATCCATATT
TATGAATAGTTTATTTAAAAAACAACCACTATATATATTTGGAGATGGTAGTGCCTTAAGAGATTACATCTTTGTAGAAG
ATATCGTTGACGCTAATATTGCAGCTCTCAGCAGTGGAAGCAAAGAGAGATTTAATATAGGCACTGGAGTTTATACTTCT
GTCAAGGAACTAGCTGAAAATATGATAGATATCATTGGCCTAAAATGTAATATAGAGTATGAATCAGCTAGAAAAGGAGA
TATAGCAAATTCATATTTTAATATTAGTAAAGCTAAAAATAAACTTAACTGGATTCCAAAATTTAGTTTGAAAGATGGAC
TGAAGAAAACTATAGAATATTATAAAAATAATCTAGAAGATTAA

Upstream 100 bases:

>100_bases
TATTTTCACAATATGATACCTATCATAATATTATGAAAATATGGATTACTACATCCATTAGTTGGTTATTTTAATTTGCT
GTAAAAAAGGAGAGAGCTTT

Downstream 100 bases:

>100_bases
AAAGTAAAAAAGAAGAACGCAGCAAGTATTATAAACGTAGGTACAACTATTGTTTGCATTGTAACAATGCCAATTATGGT
TTGGTTGTATCAGATATAAG

Product: NAD-dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MKVLVSGGAGFIGSNLVDKLINLGHNVCIIDNLSTGNINNVNKKAQLYINDILDPNVSKIFEKEKFDIVYHLAAQIDVQK
SITNPIFDSDVNVCGTINIINNCVNYNVKKIVYSSSAAVYGHPGYLPIDEKHGIRPISYYGLSKYTAEEYIRLFSNLNNL
DFTILRYANVYGIRQDPKGEGGVISIFMNSLFKKQPLYIFGDGSALRDYIFVEDIVDANIAALSSGSKERFNIGTGVYTS
VKELAENMIDIIGLKCNIEYESARKGDIANSYFNISKAKNKLNWIPKFSLKDGLKKTIEYYKNNLED

Sequences:

>Translated_307_residues
MKVLVSGGAGFIGSNLVDKLINLGHNVCIIDNLSTGNINNVNKKAQLYINDILDPNVSKIFEKEKFDIVYHLAAQIDVQK
SITNPIFDSDVNVCGTINIINNCVNYNVKKIVYSSSAAVYGHPGYLPIDEKHGIRPISYYGLSKYTAEEYIRLFSNLNNL
DFTILRYANVYGIRQDPKGEGGVISIFMNSLFKKQPLYIFGDGSALRDYIFVEDIVDANIAALSSGSKERFNIGTGVYTS
VKELAENMIDIIGLKCNIEYESARKGDIANSYFNISKAKNKLNWIPKFSLKDGLKKTIEYYKNNLED
>Mature_307_residues
MKVLVSGGAGFIGSNLVDKLINLGHNVCIIDNLSTGNINNVNKKAQLYINDILDPNVSKIFEKEKFDIVYHLAAQIDVQK
SITNPIFDSDVNVCGTINIINNCVNYNVKKIVYSSSAAVYGHPGYLPIDEKHGIRPISYYGLSKYTAEEYIRLFSNLNNL
DFTILRYANVYGIRQDPKGEGGVISIFMNSLFKKQPLYIFGDGSALRDYIFVEDIVDANIAALSSGSKERFNIGTGVYTS
VKELAENMIDIIGLKCNIEYESARKGDIANSYFNISKAKNKLNWIPKFSLKDGLKKTIEYYKNNLED

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=338, Percent_Identity=32.8402366863905, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI56118217, Length=338, Percent_Identity=32.8402366863905, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI189083684, Length=338, Percent_Identity=32.8402366863905, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI42516563, Length=315, Percent_Identity=28.8888888888889, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI7657641, Length=323, Percent_Identity=34.0557275541796, Blast_Score=137, Evalue=9e-33,
Organism=Homo sapiens, GI193211614, Length=238, Percent_Identity=26.0504201680672, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI8393516, Length=238, Percent_Identity=26.0504201680672, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=29.0419161676647, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788353, Length=340, Percent_Identity=29.4117647058824, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI48994969, Length=335, Percent_Identity=27.4626865671642, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1790049, Length=271, Percent_Identity=29.1512915129151, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788365, Length=327, Percent_Identity=19.8776758409786, Blast_Score=71, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=329, Percent_Identity=33.7386018237082, Blast_Score=150, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI71982038, Length=331, Percent_Identity=33.5347432024169, Blast_Score=149, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17539532, Length=316, Percent_Identity=28.1645569620253, Blast_Score=137, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17568069, Length=323, Percent_Identity=28.4829721362229, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115532424, Length=321, Percent_Identity=26.791277258567, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319493, Length=338, Percent_Identity=31.3609467455621, Blast_Score=136, Evalue=4e-33,
Organism=Drosophila melanogaster, GI21356223, Length=314, Percent_Identity=29.9363057324841, Blast_Score=153, Evalue=1e-37,
Organism=Drosophila melanogaster, GI19923002, Length=338, Percent_Identity=31.6568047337278, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34337; Mature: 34337

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVSGGAGFIGSNLVDKLINLGHNVCIIDNLSTGNINNVNKKAQLYINDILDPNVSKI
CEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCHHHH
FEKEKFDIVYHLAAQIDVQKSITNPIFDSDVNVCGTINIINNCVNYNVKKIVYSSSAAVY
HHHHHHHEEEEHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHCCCEEEEEEECCCEEE
GHPGYLPIDEKHGIRPISYYGLSKYTAEEYIRLFSNLNNLDFTILRYANVYGIRQDPKGE
CCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCCCCCCC
GGVISIFMNSLFKKQPLYIFGDGSALRDYIFVEDIVDANIAALSSGSKERFNIGTGVYTS
CCEEHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCHHHHCCCCCCEEECCCCHHHH
VKELAENMIDIIGLKCNIEYESARKGDIANSYFNISKAKNKLNWIPKFSLKDGLKKTIEY
HHHHHHHHHHHEEEEEEEECCCCCCCCCCHHHEEHHHHHHHHCCCCCCHHHHHHHHHHHH
YKNNLED
HHHCCCC
>Mature Secondary Structure
MKVLVSGGAGFIGSNLVDKLINLGHNVCIIDNLSTGNINNVNKKAQLYINDILDPNVSKI
CEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCHHHH
FEKEKFDIVYHLAAQIDVQKSITNPIFDSDVNVCGTINIINNCVNYNVKKIVYSSSAAVY
HHHHHHHEEEEHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHCCCEEEEEEECCCEEE
GHPGYLPIDEKHGIRPISYYGLSKYTAEEYIRLFSNLNNLDFTILRYANVYGIRQDPKGE
CCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCCCCCCC
GGVISIFMNSLFKKQPLYIFGDGSALRDYIFVEDIVDANIAALSSGSKERFNIGTGVYTS
CCEEHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCHHHHCCCCCCEEECCCCHHHH
VKELAENMIDIIGLKCNIEYESARKGDIANSYFNISKAKNKLNWIPKFSLKDGLKKTIEY
HHHHHHHHHHHEEEEEEEECCCCCCCCCCHHHEEHHHHHHHHCCCCCCHHHHHHHHHHHH
YKNNLED
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]