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The map label for this gene is hsdS [C]

Identifier: 226949372

GI number: 226949372

Start: 2361485

End: 2362837

Strand: Reverse

Name: hsdS [C]

Synonym: CLM_2295

Alternate gene names: 226949372

Gene position: 2362837-2361485 (Counterclockwise)

Preceding gene: 226949373

Following gene: 226949371

Centisome position: 56.86

GC content: 29.64

Gene sequence:

>1353_bases
ATGACTAGGAAGATGAAAGATAGTGGTGTTGAATGGATTGGGTATATGAATACTTGTTGGAAGACAATGCCTTTGAAATT
TATTTTAAAAGAGCGTAGGCAAAAGAATTCACCTATTATTACCAAAGAGAGATTGTCATTATCTATTGGTGTTGGAGTTA
CTCTTTATTCAGAAAAGACTACTAATTTAGATAGGTTTAAAGATGATGTAACTCAATATAAAGTTGCTTATCCAAATGAT
TTAGTTATTAATAGTATGAATGTTATAGTGGGTGCAGAAGGAATTTCTAATTATTTAGGATGTGTAAGCCCTGCCTATTA
TGTAATGTGTTCTAGTAATCCACAAAAGTTTATTACCAAATATTATGATTATTGTTTTAAAACATCAACAATACAAAAAG
CTCTATTTTATTTAGGAAAGGGAATTATGGCTATAGATAGAGGTGAAGGAAGAGTAAATACATGTAGATTGAAAGTTTCA
AGTTATGATTTGGGAAGATTAGAGTTTCCTGTTCCATCAGTTAATGAGCAACATCGAATAGTAGAATTTTTAGATAATAG
ATGTAATAAAATAGACCAAACAATACAAAAGGAAAAGCAAGTAATAGAAAAGCTAAAAGAATACAAACAAAGTGTCATAA
CAGAAGCAGTTACAAAAGGATTAAATCCTGATGTTAAGATGAAAGATAGTGGAGTTGAATGGATTGGAGAGATTCCTAAG
CATTGGAAGGTTGAAAAGTTAAAACATATTTTTTCATTTAAGAAGGGATTATCTATAACAAAGGATAATCTTGTAGAAGA
AGGAATCAAAGTAATTAGTTATGGACAAATTCACTCTAAAAGCAATATTGGGGTATGTATAAATGATTCTTTAATAAGAT
ATGTAGGAGAAGAATATTTAGAAACAGGAAAGCAATCGCTTGTATTAAGAAATGATTTCATTTTTGCTGATACTTCTGAA
GATTTAGAGGGAGCTGGAAACTATGTTTATGTAGGTAAAAATGAAGAGATTTTTGCTGGGTATCATACTATTATACTTAC
TCCAATTAAAGACGACATTATGTCAGAGTGGAAGTACTTTGCATATTTATATAAAACTGATTGTTGGAGAAGTCAGATAC
GCTCAAGAGTATCTGGAATAAAGTTGTTTAGTATTACTCAAAAGATATTGAAACAAACAGAAGTGATTGTACCAGATATT
AAAGAGCAGAAAGAAATAACAGATTACTTAGATAAGAAATGTTCATCCATAGATAAGCTAATATCAGACAAAGAAAAAGT
AATTAAAAAGCTAACAGAATACAAAAAATCATTAATCTATGAATGTGTAACTGGTAAAAAGGAGGTGCAGTAG

Upstream 100 bases:

>100_bases
TATTTCTATAAATATGTACCACCAAAGCCAGCAAAAGAACTTGAAATGGAAATAAGAGAAATAGAAATGGAACTAGATGG
TGTATTGGAGGAAATATTCA

Downstream 100 bases:

>100_bases
CCATGAATGAAGAAGAATTAAAGGAAAAAGCCTTTGAAGAAGCTATAGAGCAATACCTTATAACAGAAGGTGGATATATA
AAAGGTAATCCTAAGAATTT

Product: restriction modification system DNA specificity domain-containing protein

Products: NA

Alternate protein names: Restriction System DNA Specificity Domain Protein; Type I Restriction- System Specificity Subunit; Restriction Endonuclease S Subunit; Type I Restriction- System S Subunit; Type I Restriction- System Specificity Determinant; Type I Restriction S Subunit; Restriction System DNA Specificity Domain; Type I Restriction- System; Type I Site-Specific Restriction- System S Subunit; Type I Restriction Specificity Protein; Type I Restriction-; Type I Restriction DNA Specificity Domain Protein; Type I Restriction- Subunit S; Type I Restriction- System Specifity Subunit; Restriction Endonuclease S Subunits-Like; Type I Restriction System DNA Specificity Domain Protein; Type I Restriction DNA Specificity Protein; Type I DNA Specificity S Subunit; Type I Restriction- Methylase S Subunit; Type I Restriction-Mod; Type I Restriction System Specificity Protein HsdS; Type I Restriction- System Subunit S; Type I Restriction- System Specificity Subunit S; Type I Restriction; Restriction Endonuclease S Subunits-Like Protein; Type I Restriction- System Specificity Protein; Type 1 Restriction- System Endonuclease Subunit; Type I Site-Specific Deoxyribonuclease; Type I Restriction- System S Protein; Restriction Endonuclease S Subunits

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MTRKMKDSGVEWIGYMNTCWKTMPLKFILKERRQKNSPIITKERLSLSIGVGVTLYSEKTTNLDRFKDDVTQYKVAYPND
LVINSMNVIVGAEGISNYLGCVSPAYYVMCSSNPQKFITKYYDYCFKTSTIQKALFYLGKGIMAIDRGEGRVNTCRLKVS
SYDLGRLEFPVPSVNEQHRIVEFLDNRCNKIDQTIQKEKQVIEKLKEYKQSVITEAVTKGLNPDVKMKDSGVEWIGEIPK
HWKVEKLKHIFSFKKGLSITKDNLVEEGIKVISYGQIHSKSNIGVCINDSLIRYVGEEYLETGKQSLVLRNDFIFADTSE
DLEGAGNYVYVGKNEEIFAGYHTIILTPIKDDIMSEWKYFAYLYKTDCWRSQIRSRVSGIKLFSITQKILKQTEVIVPDI
KEQKEITDYLDKKCSSIDKLISDKEKVIKKLTEYKKSLIYECVTGKKEVQ

Sequences:

>Translated_450_residues
MTRKMKDSGVEWIGYMNTCWKTMPLKFILKERRQKNSPIITKERLSLSIGVGVTLYSEKTTNLDRFKDDVTQYKVAYPND
LVINSMNVIVGAEGISNYLGCVSPAYYVMCSSNPQKFITKYYDYCFKTSTIQKALFYLGKGIMAIDRGEGRVNTCRLKVS
SYDLGRLEFPVPSVNEQHRIVEFLDNRCNKIDQTIQKEKQVIEKLKEYKQSVITEAVTKGLNPDVKMKDSGVEWIGEIPK
HWKVEKLKHIFSFKKGLSITKDNLVEEGIKVISYGQIHSKSNIGVCINDSLIRYVGEEYLETGKQSLVLRNDFIFADTSE
DLEGAGNYVYVGKNEEIFAGYHTIILTPIKDDIMSEWKYFAYLYKTDCWRSQIRSRVSGIKLFSITQKILKQTEVIVPDI
KEQKEITDYLDKKCSSIDKLISDKEKVIKKLTEYKKSLIYECVTGKKEVQ
>Mature_449_residues
TRKMKDSGVEWIGYMNTCWKTMPLKFILKERRQKNSPIITKERLSLSIGVGVTLYSEKTTNLDRFKDDVTQYKVAYPNDL
VINSMNVIVGAEGISNYLGCVSPAYYVMCSSNPQKFITKYYDYCFKTSTIQKALFYLGKGIMAIDRGEGRVNTCRLKVSS
YDLGRLEFPVPSVNEQHRIVEFLDNRCNKIDQTIQKEKQVIEKLKEYKQSVITEAVTKGLNPDVKMKDSGVEWIGEIPKH
WKVEKLKHIFSFKKGLSITKDNLVEEGIKVISYGQIHSKSNIGVCINDSLIRYVGEEYLETGKQSLVLRNDFIFADTSED
LEGAGNYVYVGKNEEIFAGYHTIILTPIKDDIMSEWKYFAYLYKTDCWRSQIRSRVSGIKLFSITQKILKQTEVIVPDIK
EQKEITDYLDKKCSSIDKLISDKEKVIKKLTEYKKSLIYECVTGKKEVQ

Specific function: The M And S Subunits Together Form A Methyltransferase (Mtase) That Methylates Two Adenine Residues In Complementary Strands Of A Bipartite DNA Recognition Sequence. In The Presence Of The R Subunit The Complex Can Also Act As An Endonuclease, Binding To

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 51871; Mature: 51739

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKMKDSGVEWIGYMNTCWKTMPLKFILKERRQKNSPIITKERLSLSIGVGVTLYSEKT
CCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEHHHEEEEECCCEEEECCCC
TNLDRFKDDVTQYKVAYPNDLVINSMNVIVGAEGISNYLGCVSPAYYVMCSSNPQKFITK
CCHHHHHHHHHHEEEECCCCEEEECCEEEEECHHHHHHHHHCCCEEEEEECCCHHHHHHH
YYDYCFKTSTIQKALFYLGKGIMAIDRGEGRVNTCRLKVSSYDLGRLEFPVPSVNEQHRI
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEEECCCCCCEECCCCCCCCHHHH
VEFLDNRCNKIDQTIQKEKQVIEKLKEYKQSVITEAVTKGLNPDVKMKDSGVEWIGEIPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHCCCC
HWKVEKLKHIFSFKKGLSITKDNLVEEGIKVISYGQIHSKSNIGVCINDSLIRYVGEEYL
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEECCEECCCCCCEEECHHHHHHHHHHHH
ETGKQSLVLRNDFIFADTSEDLEGAGNYVYVGKNEEIFAGYHTIILTPIKDDIMSEWKYF
HCCCHHEEEECCEEEECCCHHHCCCCCEEEECCCCCEEECEEEEEEECCHHHHHHHHHHH
AYLYKTDCWRSQIRSRVSGIKLFSITQKILKQTEVIVPDIKEQKEITDYLDKKCSSIDKL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHHHHHHHH
ISDKEKVIKKLTEYKKSLIYECVTGKKEVQ
HCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TRKMKDSGVEWIGYMNTCWKTMPLKFILKERRQKNSPIITKERLSLSIGVGVTLYSEKT
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEHHHEEEEECCCEEEECCCC
TNLDRFKDDVTQYKVAYPNDLVINSMNVIVGAEGISNYLGCVSPAYYVMCSSNPQKFITK
CCHHHHHHHHHHEEEECCCCEEEECCEEEEECHHHHHHHHHCCCEEEEEECCCHHHHHHH
YYDYCFKTSTIQKALFYLGKGIMAIDRGEGRVNTCRLKVSSYDLGRLEFPVPSVNEQHRI
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEEECCCCCCEECCCCCCCCHHHH
VEFLDNRCNKIDQTIQKEKQVIEKLKEYKQSVITEAVTKGLNPDVKMKDSGVEWIGEIPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHCCCC
HWKVEKLKHIFSFKKGLSITKDNLVEEGIKVISYGQIHSKSNIGVCINDSLIRYVGEEYL
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEECCEECCCCCCEEECHHHHHHHHHHHH
ETGKQSLVLRNDFIFADTSEDLEGAGNYVYVGKNEEIFAGYHTIILTPIKDDIMSEWKYF
HCCCHHEEEECCEEEECCCHHHCCCCCEEEECCCCCEEECEEEEEEECCHHHHHHHHHHH
AYLYKTDCWRSQIRSRVSGIKLFSITQKILKQTEVIVPDIKEQKEITDYLDKKCSSIDKL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHHHHHHHH
ISDKEKVIKKLTEYKKSLIYECVTGKKEVQ
HCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA