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The map label for this gene is lip [H]

Identifier: 226949354

GI number: 226949354

Start: 2345894

End: 2347183

Strand: Reverse

Name: lip [H]

Synonym: CLM_2277

Alternate gene names: 226949354

Gene position: 2347183-2345894 (Counterclockwise)

Preceding gene: 226949355

Following gene: 226949353

Centisome position: 56.49

GC content: 36.59

Gene sequence:

>1290_bases
ATGAAAAGATCTTATTTTAAAAGGATTATGGTATCTATTATTATCATCTGTACAGTTTTTTGTTTCACCTCAATTTCTAC
TGTAAAAGCTGCTGGTAACAGTGATGCTATGGGAGTCGGAAATAATTATCCCATAGTTATGGTACATGGATGTTTTGGTT
GGGGAAGCAATGAAGGAGCCGGTCTCTATTACTGGGGAGGTAAAGAAAGTCTGACTCAAAAGCTTACCGAGAAGGGCTAT
ACTGTATATTCTCCATCTATCGGACCTGTTTCAAGTAACTGGGATAGGGCATGTGAGCTGTATACATATATTGTAGGCGG
CACAGTTGATTATGGTGAATCACACTCTAAAAAATATGGACATGAAAGATATGGACGAAGTTATCCAGGCGTGTACAAAC
AAATTGGAACAAAAGATTCATCTGGAAATGTTCAAAAAATTCATCTAATTGGACATAGTATGGGAGGACAGACAATCCGT
CTATTAGCACAGCTTTTAGAAAATGGAGATCCTAATGAATTATCATTTACCACAGATGGAAGCATCAATTCCCTTTTTAC
TGGCGGCAAATCATGGGTGTCCAGTATTACATCTATTGCTACTCCGCATGATGGAAGCCAGGAAGCACATATAAAATGTG
ATATTGAGCCTCTCACACATCAATTTGTTGCAGCTATTGCCGCAATAAAAGGCAAAAATGTTAATTTAGATGACTTAAAT
TACGATTTTCAATTAGATCAGTGGGGCCTTAAAAGAAAGCCTGGTGAATCACGTTTAGCCTACAACAATAGAGTAATTAA
AAGTGAAATTTGGAAAAAAACAAAGGATTTAAGTGTCTGGGATTTGTCACCGGAAGGAGCCCGGGAATTTAATTCCTACG
TTAAGGCACAAAGTGATATCGACTATTTTTCAATTGCATGTGTAAATACTCATGAAGATAAATTGACTCATTTTCAGGTG
CCAAACAAAAAAATGAATCCAGTTCTTGTGAAAAGTTCTATATTTATGGGTATGTATACAAACAATAAGAGTGGTGAAGT
TCCTATAGATAAAAGCTGGTGGAGAAATGACGGAGTTGTGAGTGTGATATCAGCTACAAACCCTAAGGTAGGTTCAACAG
ACAAAATAGTTGATTATAGCGGGACTGCCGTAAAGGGTACATGGAATTATCTTGGTGAATTGGATAATACAGATCATATT
GAGGTTTGTGGAATGAAATATGATCGAAACGGAATTGAACAAATGTATTTTAATGTGGCAGAAATGCTTTCAAAACTCCC
TGTTGAATAA

Upstream 100 bases:

>100_bases
GGATACTCCAATTGAAATTTACTATTAATTTAATCAAAATAAAATAAATTATATAGCCTAGCTGCTGGCTACAGAATTTA
TGATGTAAAGGAGCATGGGT

Downstream 100 bases:

>100_bases
TTCAGCATATGATGATGGATTATTTAAAAATAACTTACCCTATGTTATAATTTTCAATATAGATAAAGCATTGGGGGATG
GCAACTTGGCACAGCAATAT

Product: triacylglycerol lipase

Products: NA

Alternate protein names: Glycerol ester hydrolase [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MKRSYFKRIMVSIIIICTVFCFTSISTVKAAGNSDAMGVGNNYPIVMVHGCFGWGSNEGAGLYYWGGKESLTQKLTEKGY
TVYSPSIGPVSSNWDRACELYTYIVGGTVDYGESHSKKYGHERYGRSYPGVYKQIGTKDSSGNVQKIHLIGHSMGGQTIR
LLAQLLENGDPNELSFTTDGSINSLFTGGKSWVSSITSIATPHDGSQEAHIKCDIEPLTHQFVAAIAAIKGKNVNLDDLN
YDFQLDQWGLKRKPGESRLAYNNRVIKSEIWKKTKDLSVWDLSPEGAREFNSYVKAQSDIDYFSIACVNTHEDKLTHFQV
PNKKMNPVLVKSSIFMGMYTNNKSGEVPIDKSWWRNDGVVSVISATNPKVGSTDKIVDYSGTAVKGTWNYLGELDNTDHI
EVCGMKYDRNGIEQMYFNVAEMLSKLPVE

Sequences:

>Translated_429_residues
MKRSYFKRIMVSIIIICTVFCFTSISTVKAAGNSDAMGVGNNYPIVMVHGCFGWGSNEGAGLYYWGGKESLTQKLTEKGY
TVYSPSIGPVSSNWDRACELYTYIVGGTVDYGESHSKKYGHERYGRSYPGVYKQIGTKDSSGNVQKIHLIGHSMGGQTIR
LLAQLLENGDPNELSFTTDGSINSLFTGGKSWVSSITSIATPHDGSQEAHIKCDIEPLTHQFVAAIAAIKGKNVNLDDLN
YDFQLDQWGLKRKPGESRLAYNNRVIKSEIWKKTKDLSVWDLSPEGAREFNSYVKAQSDIDYFSIACVNTHEDKLTHFQV
PNKKMNPVLVKSSIFMGMYTNNKSGEVPIDKSWWRNDGVVSVISATNPKVGSTDKIVDYSGTAVKGTWNYLGELDNTDHI
EVCGMKYDRNGIEQMYFNVAEMLSKLPVE
>Mature_429_residues
MKRSYFKRIMVSIIIICTVFCFTSISTVKAAGNSDAMGVGNNYPIVMVHGCFGWGSNEGAGLYYWGGKESLTQKLTEKGY
TVYSPSIGPVSSNWDRACELYTYIVGGTVDYGESHSKKYGHERYGRSYPGVYKQIGTKDSSGNVQKIHLIGHSMGGQTIR
LLAQLLENGDPNELSFTTDGSINSLFTGGKSWVSSITSIATPHDGSQEAHIKCDIEPLTHQFVAAIAAIKGKNVNLDDLN
YDFQLDQWGLKRKPGESRLAYNNRVIKSEIWKKTKDLSVWDLSPEGAREFNSYVKAQSDIDYFSIACVNTHEDKLTHFQV
PNKKMNPVLVKSSIFMGMYTNNKSGEVPIDKSWWRNDGVVSVISATNPKVGSTDKIVDYSGTAVKGTWNYLGELDNTDHI
EVCGMKYDRNGIEQMYFNVAEMLSKLPVE

Specific function: Unknown

COG id: COG1075

COG function: function code R; Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Lipase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005877 [H]

Pfam domain/function: PF04650 YSIRK_signal [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 47682; Mature: 47682

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSYFKRIMVSIIIICTVFCFTSISTVKAAGNSDAMGVGNNYPIVMVHGCFGWGSNEGA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEEEEEEECCCCCCCC
GLYYWGGKESLTQKLTEKGYTVYSPSIGPVSSNWDRACELYTYIVGGTVDYGESHSKKYG
EEEEECCHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHEEEEEEECCEECCCCCHHHHCC
HERYGRSYPGVYKQIGTKDSSGNVQKIHLIGHSMGGQTIRLLAQLLENGDPNELSFTTDG
HHHHCCCCCCHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCC
SINSLFTGGKSWVSSITSIATPHDGSQEAHIKCDIEPLTHQFVAAIAAIKGKNVNLDDLN
CCHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCC
YDFQLDQWGLKRKPGESRLAYNNRVIKSEIWKKTKDLSVWDLSPEGAREFNSYVKAQSDI
CEEEECCCCCCCCCCCCCHHCCCEEHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCC
DYFSIACVNTHEDKLTHFQVPNKKMNPVLVKSSIFMGMYTNNKSGEVPIDKSWWRNDGVV
CEEEEEEECCCCCCCEEEECCCCCCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCEE
SVISATNPKVGSTDKIVDYSGTAVKGTWNYLGELDNTDHIEVCGMKYDRNGIEQMYFNVA
EEEECCCCCCCCCCCEEECCCCEEECCHHHHCCCCCCCCEEEECEEECCCHHHHHHHHHH
EMLSKLPVE
HHHHHCCCC
>Mature Secondary Structure
MKRSYFKRIMVSIIIICTVFCFTSISTVKAAGNSDAMGVGNNYPIVMVHGCFGWGSNEGA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEEEEEEECCCCCCCC
GLYYWGGKESLTQKLTEKGYTVYSPSIGPVSSNWDRACELYTYIVGGTVDYGESHSKKYG
EEEEECCHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHEEEEEEECCEECCCCCHHHHCC
HERYGRSYPGVYKQIGTKDSSGNVQKIHLIGHSMGGQTIRLLAQLLENGDPNELSFTTDG
HHHHCCCCCCHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCC
SINSLFTGGKSWVSSITSIATPHDGSQEAHIKCDIEPLTHQFVAAIAAIKGKNVNLDDLN
CCHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCC
YDFQLDQWGLKRKPGESRLAYNNRVIKSEIWKKTKDLSVWDLSPEGAREFNSYVKAQSDI
CEEEECCCCCCCCCCCCCHHCCCEEHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCC
DYFSIACVNTHEDKLTHFQVPNKKMNPVLVKSSIFMGMYTNNKSGEVPIDKSWWRNDGVV
CEEEEEEECCCCCCCEEEECCCCCCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCEE
SVISATNPKVGSTDKIVDYSGTAVKGTWNYLGELDNTDHIEVCGMKYDRNGIEQMYFNVA
EEEECCCCCCCCCCCEEECCCCEEECCHHHHCCCCCCCCEEEECEEECCCHHHHHHHHHH
EMLSKLPVE
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8436947 [H]