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The map label for this gene is 226949316

Identifier: 226949316

GI number: 226949316

Start: 2306001

End: 2307140

Strand: Reverse

Name: 226949316

Synonym: CLM_2237

Alternate gene names: NA

Gene position: 2307140-2306001 (Counterclockwise)

Preceding gene: 226949317

Following gene: 226949315

Centisome position: 55.52

GC content: 33.6

Gene sequence:

>1140_bases
ATGAAGATACCATATGTTATGACACCAGGCCCTACCATGGTAAGAGAAAATGTTAGAATGGCAAGGGCTATGGAAACAAC
AAACCCAGATTTAGATTTACAATTTTATGATTATTATAAAGAAACCTGTGAAAAAATAGGTGAATTTTTAAAGACTAGAA
ATGAGGTAAGAATATTAAGCGGAGAGGGTATACTAGGTTTGGAAGCAGCTTGTGCTTCATTAACAGAAAAAGGTGACAGA
ATTCTTGTAATTGACAACGGAATTTTTGGCGAAGGTTTTGCAGATTTTGTAGAAATCTACGGGGGAGAAGCAGTATTTTT
TAAAGGAGATAGAAAAAGAGATATAGATATAGAAAAGTTAAAAGAATTTCTAGAAAAGGATAGTGACTTTAAATATGCTA
CTGTTGTACATTGTGATACTCCCTCAGGAGTTATTAATGATGTATCAAAAATATGTCCAATGCTTAAAGAAAAGGGCATA
ATAACTGTAGTAGATTCTGTATCTGCCATGGGTGGACAGGAGCTAAAGGTGGATGAATGGAAAATAGATATGGTACTTGG
TGGATCTCAAAAATGTATGTCAGCCCCTCCAGGACTTTCATTTCTTAGTATAAGTGAAGATGCCTTTAAAACTATGGAAG
AAAGAAGAACACCTATAGCATCATATTACTGTAATCTCCTTGTATGGAAGGATTATTATAAAAATAAATGGTTCCCATAC
ACTCCACCTATAAGTGATATAGTTGGGCTAAGAGTAGCGGTGGATAATATTTTAAAGGATAGAGACATCCTATCAAGACA
CAATAATATAGCAAAAGCTTGTAGAGAGGCTATAGTAGAGAGTGGACTTAAGCTTTATTTAGAAAAGGGTTATTCTAACA
CTGTTACTGTTATAGAACTACCTAAAGAAATAGAGGATAAAGCATTAAGAACATATATGCAGGATAAATACAATGTAATC
ATAGCAGGTTCCTTTGGATATCTTCATGGTAAGGTTATAAGAATAGGTCATATGGGTGAAAATGCTAAAGTGGATAAAAT
GGCCTATACATTATTTGCACTTAGAAATAGCTTAGAGCATTTAGGATACAAACTAAGAGCTAATATTGGAGAAGTTTTCT
TACAAAAAGTTATGGAGTAG

Upstream 100 bases:

>100_bases
AAAATGTAAAACTGCTTAAAATGCAGGGATACACTTTTAGTTATAGAATAAGTGGAATATAATTCTACTTAGATATGTTT
AAGTAGGAGGATTTGATTTT

Downstream 100 bases:

>100_bases
GAGTGAATATTATTATTTCAAAAATTATTATTTTTGATCTTATATTAATCATAATTTATTTGTACAAGAGCTTAAAAAGC
CAAGAGAAAATAGATAAGAG

Product: class V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKIPYVMTPGPTMVRENVRMARAMETTNPDLDLQFYDYYKETCEKIGEFLKTRNEVRILSGEGILGLEAACASLTEKGDR
ILVIDNGIFGEGFADFVEIYGGEAVFFKGDRKRDIDIEKLKEFLEKDSDFKYATVVHCDTPSGVINDVSKICPMLKEKGI
ITVVDSVSAMGGQELKVDEWKIDMVLGGSQKCMSAPPGLSFLSISEDAFKTMEERRTPIASYYCNLLVWKDYYKNKWFPY
TPPISDIVGLRVAVDNILKDRDILSRHNNIAKACREAIVESGLKLYLEKGYSNTVTVIELPKEIEDKALRTYMQDKYNVI
IAGSFGYLHGKVIRIGHMGENAKVDKMAYTLFALRNSLEHLGYKLRANIGEVFLQKVME

Sequences:

>Translated_379_residues
MKIPYVMTPGPTMVRENVRMARAMETTNPDLDLQFYDYYKETCEKIGEFLKTRNEVRILSGEGILGLEAACASLTEKGDR
ILVIDNGIFGEGFADFVEIYGGEAVFFKGDRKRDIDIEKLKEFLEKDSDFKYATVVHCDTPSGVINDVSKICPMLKEKGI
ITVVDSVSAMGGQELKVDEWKIDMVLGGSQKCMSAPPGLSFLSISEDAFKTMEERRTPIASYYCNLLVWKDYYKNKWFPY
TPPISDIVGLRVAVDNILKDRDILSRHNNIAKACREAIVESGLKLYLEKGYSNTVTVIELPKEIEDKALRTYMQDKYNVI
IAGSFGYLHGKVIRIGHMGENAKVDKMAYTLFALRNSLEHLGYKLRANIGEVFLQKVME
>Mature_379_residues
MKIPYVMTPGPTMVRENVRMARAMETTNPDLDLQFYDYYKETCEKIGEFLKTRNEVRILSGEGILGLEAACASLTEKGDR
ILVIDNGIFGEGFADFVEIYGGEAVFFKGDRKRDIDIEKLKEFLEKDSDFKYATVVHCDTPSGVINDVSKICPMLKEKGI
ITVVDSVSAMGGQELKVDEWKIDMVLGGSQKCMSAPPGLSFLSISEDAFKTMEERRTPIASYYCNLLVWKDYYKNKWFPY
TPPISDIVGLRVAVDNILKDRDILSRHNNIAKACREAIVESGLKLYLEKGYSNTVTVIELPKEIEDKALRTYMQDKYNVI
IAGSFGYLHGKVIRIGHMGENAKVDKMAYTLFALRNSLEHLGYKLRANIGEVFLQKVME

Specific function: Unknown

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=364, Percent_Identity=26.6483516483516, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17536281, Length=361, Percent_Identity=26.5927977839335, Blast_Score=130, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6321079, Length=366, Percent_Identity=26.2295081967213, Blast_Score=106, Evalue=5e-24,
Organism=Drosophila melanogaster, GI17530823, Length=382, Percent_Identity=28.0104712041885, Blast_Score=146, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 42885; Mature: 42885

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIPYVMTPGPTMVRENVRMARAMETTNPDLDLQFYDYYKETCEKIGEFLKTRNEVRILS
CCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
GEGILGLEAACASLTEKGDRILVIDNGIFGEGFADFVEIYGGEAVFFKGDRKRDIDIEKL
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCHHHH
KEFLEKDSDFKYATVVHCDTPSGVINDVSKICPMLKEKGIITVVDSVSAMGGQELKVDEW
HHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEECHHHCCCCCEEECCE
KIDMVLGGSQKCMSAPPGLSFLSISEDAFKTMEERRTPIASYYCNLLVWKDYYKNKWFPY
EEEEEECCCHHHCCCCCCCEEEEECHHHHHHHHHHCCHHHHHHHHHEEEEHHHCCCCCCC
TPPISDIVGLRVAVDNILKDRDILSRHNNIAKACREAIVESGLKLYLEKGYSNTVTVIEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHCCCCCCEEEEEEC
PKEIEDKALRTYMQDKYNVIIAGSFGYLHGKVIRIGHMGENAKVDKMAYTLFALRNSLEH
CHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
LGYKLRANIGEVFLQKVME
CCCHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MKIPYVMTPGPTMVRENVRMARAMETTNPDLDLQFYDYYKETCEKIGEFLKTRNEVRILS
CCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
GEGILGLEAACASLTEKGDRILVIDNGIFGEGFADFVEIYGGEAVFFKGDRKRDIDIEKL
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCHHHH
KEFLEKDSDFKYATVVHCDTPSGVINDVSKICPMLKEKGIITVVDSVSAMGGQELKVDEW
HHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEECHHHCCCCCEEECCE
KIDMVLGGSQKCMSAPPGLSFLSISEDAFKTMEERRTPIASYYCNLLVWKDYYKNKWFPY
EEEEEECCCHHHCCCCCCCEEEEECHHHHHHHHHHCCHHHHHHHHHEEEEHHHCCCCCCC
TPPISDIVGLRVAVDNILKDRDILSRHNNIAKACREAIVESGLKLYLEKGYSNTVTVIEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHCCCCCCEEEEEEC
PKEIEDKALRTYMQDKYNVIIAGSFGYLHGKVIRIGHMGENAKVDKMAYTLFALRNSLEH
CHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
LGYKLRANIGEVFLQKVME
CCCHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]