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The map label for this gene is aroK [H]

Identifier: 226949197

GI number: 226949197

Start: 2169100

End: 2169612

Strand: Reverse

Name: aroK [H]

Synonym: CLM_2116

Alternate gene names: 226949197

Gene position: 2169612-2169100 (Counterclockwise)

Preceding gene: 226949198

Following gene: 226949196

Centisome position: 52.21

GC content: 25.34

Gene sequence:

>513_bases
TTGGAGAATATTGTTTTAATAGGCATGCCTTTAAGTGGAAAAAGCACTTTAGGTAGAGAGCTTAGTAAGATTTTAAAATA
TGATCTTATAGATACGGATACACTTATAGAAGAGATGGAAGATAAAAGTATAAAGGAAATATTTAAAATATATGGGGAAG
ATTACTTTAGAGAAAAGGAATTAAAAATTATAAATAAATTAAAAAAAGAAAGTAATAAAGTTATATCTACAGGTGGAGGC
CTTCCCATATATAATAAAAATATATATGAACTAAAAAAGATTGGTTTTACAGTATATCTTAAGGTACCATTGGAAGAGTT
AATTAAAAGAATGGTAAAGAAGGAATATGATACAAGACCTCTTTTAAAAAACAATGATACAAAATTTTTAGAGGAAATGT
ATAAAAATAGGATAGAGATTTATGAAAAGGCTCATACTATAATATGCAATACTAACTACAAAGAAAGCTTAATTACAATT
GTAAGAACCTATAAAAAATGGAAGGGTATATAA

Upstream 100 bases:

>100_bases
TAAATCTGAGATTTGTTTAATATCATATAATTATAATAAACTATTGTTACATAAGTATTTTGATTAAAAATATAATTTTT
TAGTAAAGATGGTGGTGAGT

Downstream 100 bases:

>100_bases
AAGAAAAAAATAACAATATATGTATTTTATGAAAAAATATTTGCAAATAACCATAATATTATTTGCAAATAAAGTGAAGT
TTTGATAAAATATCATTGTT

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MENIVLIGMPLSGKSTLGRELSKILKYDLIDTDTLIEEMEDKSIKEIFKIYGEDYFREKELKIINKLKKESNKVISTGGG
LPIYNKNIYELKKIGFTVYLKVPLEELIKRMVKKEYDTRPLLKNNDTKFLEEMYKNRIEIYEKAHTIICNTNYKESLITI
VRTYKKWKGI

Sequences:

>Translated_170_residues
MENIVLIGMPLSGKSTLGRELSKILKYDLIDTDTLIEEMEDKSIKEIFKIYGEDYFREKELKIINKLKKESNKVISTGGG
LPIYNKNIYELKKIGFTVYLKVPLEELIKRMVKKEYDTRPLLKNNDTKFLEEMYKNRIEIYEKAHTIICNTNYKESLITI
VRTYKKWKGI
>Mature_170_residues
MENIVLIGMPLSGKSTLGRELSKILKYDLIDTDTLIEEMEDKSIKEIFKIYGEDYFREKELKIINKLKKESNKVISTGGG
LPIYNKNIYELKKIGFTVYLKVPLEELIKRMVKKEYDTRPLLKNNDTKFLEEMYKNRIEIYEKAHTIICNTNYKESLITI
VRTYKKWKGI

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Homo sapiens, GI153792148, Length=143, Percent_Identity=33.5664335664336, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI87082255, Length=157, Percent_Identity=31.2101910828025, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1786587, Length=165, Percent_Identity=29.6969696969697, Blast_Score=70, Evalue=6e-14,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 20098; Mature: 20098

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENIVLIGMPLSGKSTLGRELSKILKYDLIDTDTLIEEMEDKSIKEIFKIYGEDYFREKE
CCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHCHHHHHHHH
LKIINKLKKESNKVISTGGGLPIYNKNIYELKKIGFTVYLKVPLEELIKRMVKKEYDTRP
HHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHCCEEEEEECCHHHHHHHHHHHCCCCCC
LLKNNDTKFLEEMYKNRIEIYEKAHTIICNTNYKESLITIVRTYKKWKGI
CCCCCCHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MENIVLIGMPLSGKSTLGRELSKILKYDLIDTDTLIEEMEDKSIKEIFKIYGEDYFREKE
CCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHCHHHHHHHH
LKIINKLKKESNKVISTGGGLPIYNKNIYELKKIGFTVYLKVPLEELIKRMVKKEYDTRP
HHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHCCEEEEEECCHHHHHHHHHHHCCCCCC
LLKNNDTKFLEEMYKNRIEIYEKAHTIICNTNYKESLITIVRTYKKWKGI
CCCCCCHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA