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The map label for this gene is xseA [H]

Identifier: 226949183

GI number: 226949183

Start: 2159632

End: 2160837

Strand: Reverse

Name: xseA [H]

Synonym: CLM_2102

Alternate gene names: 226949183

Gene position: 2160837-2159632 (Counterclockwise)

Preceding gene: 226949184

Following gene: 226949182

Centisome position: 52.0

GC content: 27.36

Gene sequence:

>1206_bases
ATGCATATTAAAACTCTTACAGTTTCTCAGTTAAATAGATATGTAAAAAATACCTTAGATGCTGATTTTATATTAAATAA
TGCTTCCGTAAAGGGTGAAATATCAAATCTTAAAATTCACAGTAGCGGCCATATTTATTTTTCCTTAAAGGATGGAGGAA
GTAAAATAAATTGTGTAATGTTTAAAAGCTATGCATATAATTTAAAGTTTGTACCAGAAAATGGCATGGACGTAGTAGCT
CTAGGAAATGTTTCTGTATATGAGAAGGAAGGCTCTTATCAATTATATGTTAAAGATATGAAAAGAGAGGGCATAGGAGA
CCTTTATGTAGCCTTTGAAAAGTTAAAAGAAAAACTTAAAGAAGAAGGACTTTTTGATGATGTACATAAAAAAGAAATAC
CTAAATTTTCTAAAAAAGTAGGGGTAATAACCTCACCTACAGGAGCAGCCCTAAAAGATATCATAAATGTAACTAAAAGA
AGAAATAAAGGGATAGAACTATTAATATATCCTGCCTTAGTACAAGGAACAGATGCTAGTAGAACTCTTATAGAGGGTAT
AAAAATATTAAATAAAGTTGAAGATGTAGATATAATAATATTAGCTCGTGGAGGAGGATCTATAGAAGAATTATGGGCTT
TTAATAATGAAGAGTTAGCTTATGCAGTGTATAATTCTAAAAAGCCTATAATAACCGGAGTAGGTCATGAAACGGATTTT
ACTATTGTAGACTTTGTAAGTGATAGAAGAGCACCTACGCCCTCTGCAGCTGCAGAAATAGCTGTTTTTGATAGAGAAGT
TCTAATAAACGAGATTTTAAATTATAAGTATAATATAAAAAATTCTATGGAAAATATAATAAAAGAAAAAAGAAGTTATT
TAAATTTATACAAACAGAAAATAGAAGCTAACAGTCCTACTAATATAATAGTAAATGAATATAAAAATATAGATAATTTA
AAAGAATTATTAAATATGAAAATAGAAGGTAAATTAAATAAAGAAAAAAACAATCTATCAAGACTATCCTCTTTACTAGA
AGCGCATAATCCACTAAATGTATTAAAAAAAGGCTATACGTTAATAGAGGATGAAGGGAATAATTTAATAACAGAAAAAG
AATCCTTAAAGAAATTAAATAAAATAAACATAATCTTTAAAGATGGTAGGGCAAAATTATCTATTGAGTATATAGAAGAA
TTTTAA

Upstream 100 bases:

>100_bases
ATAAATGGTGTTTTAGGTAAAATGATTTAAAATTAATAAATATTTAAAAAGTGAAGAGCTTAGCTTTTCACTTTTAATAT
TAATAAAAAGGAAGATGTTT

Downstream 100 bases:

>100_bases
AAATAATCCTTTAAAAGTCATACAGATATCATAGTAAACTTTATATTTATGTTATGGTAGTTTATATTTAATAATTTAGA
AATTATTAAATTGTAAATAA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MHIKTLTVSQLNRYVKNTLDADFILNNASVKGEISNLKIHSSGHIYFSLKDGGSKINCVMFKSYAYNLKFVPENGMDVVA
LGNVSVYEKEGSYQLYVKDMKREGIGDLYVAFEKLKEKLKEEGLFDDVHKKEIPKFSKKVGVITSPTGAALKDIINVTKR
RNKGIELLIYPALVQGTDASRTLIEGIKILNKVEDVDIIILARGGGSIEELWAFNNEELAYAVYNSKKPIITGVGHETDF
TIVDFVSDRRAPTPSAAAEIAVFDREVLINEILNYKYNIKNSMENIIKEKRSYLNLYKQKIEANSPTNIIVNEYKNIDNL
KELLNMKIEGKLNKEKNNLSRLSSLLEAHNPLNVLKKGYTLIEDEGNNLITEKESLKKLNKINIIFKDGRAKLSIEYIEE
F

Sequences:

>Translated_401_residues
MHIKTLTVSQLNRYVKNTLDADFILNNASVKGEISNLKIHSSGHIYFSLKDGGSKINCVMFKSYAYNLKFVPENGMDVVA
LGNVSVYEKEGSYQLYVKDMKREGIGDLYVAFEKLKEKLKEEGLFDDVHKKEIPKFSKKVGVITSPTGAALKDIINVTKR
RNKGIELLIYPALVQGTDASRTLIEGIKILNKVEDVDIIILARGGGSIEELWAFNNEELAYAVYNSKKPIITGVGHETDF
TIVDFVSDRRAPTPSAAAEIAVFDREVLINEILNYKYNIKNSMENIIKEKRSYLNLYKQKIEANSPTNIIVNEYKNIDNL
KELLNMKIEGKLNKEKNNLSRLSSLLEAHNPLNVLKKGYTLIEDEGNNLITEKESLKKLNKINIIFKDGRAKLSIEYIEE
F
>Mature_401_residues
MHIKTLTVSQLNRYVKNTLDADFILNNASVKGEISNLKIHSSGHIYFSLKDGGSKINCVMFKSYAYNLKFVPENGMDVVA
LGNVSVYEKEGSYQLYVKDMKREGIGDLYVAFEKLKEKLKEEGLFDDVHKKEIPKFSKKVGVITSPTGAALKDIINVTKR
RNKGIELLIYPALVQGTDASRTLIEGIKILNKVEDVDIIILARGGGSIEELWAFNNEELAYAVYNSKKPIITGVGHETDF
TIVDFVSDRRAPTPSAAAEIAVFDREVLINEILNYKYNIKNSMENIIKEKRSYLNLYKQKIEANSPTNIIVNEYKNIDNL
KELLNMKIEGKLNKEKNNLSRLSSLLEAHNPLNVLKKGYTLIEDEGNNLITEKESLKKLNKINIIFKDGRAKLSIEYIEE
F

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=359, Percent_Identity=36.4902506963788, Blast_Score=277, Evalue=7e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 45408; Mature: 45408

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIKTLTVSQLNRYVKNTLDADFILNNASVKGEISNLKIHSSGHIYFSLKDGGSKINCVM
CCEEEEEHHHHHHHHHHCCCHHEEEECCCCCEEEEEEEEECCCEEEEEEECCCCEEEEEE
FKSYAYNLKFVPENGMDVVALGNVSVYEKEGSYQLYVKDMKREGIGDLYVAFEKLKEKLK
EEEEEEEEEEECCCCCCEEEECCEEEEECCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHH
EEGLFDDVHKKEIPKFSKKVGVITSPTGAALKDIINVTKRRNKGIELLIYPALVQGTDAS
HCCCCCHHHHHHCCCHHHHCCEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCH
RTLIEGIKILNKVEDVDIIILARGGGSIEELWAFNNEELAYAVYNSKKPIITGVGHETDF
HHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCCCCCEEEEEECCCCCEEEECCCCCCE
TIVDFVSDRRAPTPSAAAEIAVFDREVLINEILNYKYNIKNSMENIIKEKRSYLNLYKQK
EEEEEHHCCCCCCCCHHHEEEHHHHHHHHHHHHCCEECCHHHHHHHHHHHHHHHHHHHHH
IEANSPTNIIVNEYKNIDNLKELLNMKIEGKLNKEKNNLSRLSSLLEAHNPLNVLKKGYT
HCCCCCCEEEEHHHCCHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHCCCE
LIEDEGNNLITEKESLKKLNKINIIFKDGRAKLSIEYIEEF
EEECCCCCEECCHHHHHHHHHEEEEEECCCCEEEEEEHHCC
>Mature Secondary Structure
MHIKTLTVSQLNRYVKNTLDADFILNNASVKGEISNLKIHSSGHIYFSLKDGGSKINCVM
CCEEEEEHHHHHHHHHHCCCHHEEEECCCCCEEEEEEEEECCCEEEEEEECCCCEEEEEE
FKSYAYNLKFVPENGMDVVALGNVSVYEKEGSYQLYVKDMKREGIGDLYVAFEKLKEKLK
EEEEEEEEEEECCCCCCEEEECCEEEEECCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHH
EEGLFDDVHKKEIPKFSKKVGVITSPTGAALKDIINVTKRRNKGIELLIYPALVQGTDAS
HCCCCCHHHHHHCCCHHHHCCEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCH
RTLIEGIKILNKVEDVDIIILARGGGSIEELWAFNNEELAYAVYNSKKPIITGVGHETDF
HHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCCCCCEEEEEECCCCCEEEECCCCCCE
TIVDFVSDRRAPTPSAAAEIAVFDREVLINEILNYKYNIKNSMENIIKEKRSYLNLYKQK
EEEEEHHCCCCCCCCHHHEEEHHHHHHHHHHHHCCEECCHHHHHHHHHHHHHHHHHHHHH
IEANSPTNIIVNEYKNIDNLKELLNMKIEGKLNKEKNNLSRLSSLLEAHNPLNVLKKGYT
HCCCCCCEEEEHHHCCHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHCCCE
LIEDEGNNLITEKESLKKLNKINIIFKDGRAKLSIEYIEEF
EEECCCCCEECCHHHHHHHHHEEEEEECCCCEEEEEEHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA