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The map label for this gene is dsbD [H]

Identifier: 226949060

GI number: 226949060

Start: 2041652

End: 2042338

Strand: Reverse

Name: dsbD [H]

Synonym: CLM_1976

Alternate gene names: 226949060

Gene position: 2042338-2041652 (Counterclockwise)

Preceding gene: 226949061

Following gene: 226949057

Centisome position: 49.15

GC content: 27.37

Gene sequence:

>687_bases
ATGAATGAGATTATAACAAAAGCTGTAAGCCTAATGGGAAATAATGTTCTTTTAGCCTTGTTAATATCCTTCTTAGGAGG
TATAATTTCTTCCTTTAGTCCTTGTATACTTTCATCACTTCCTTTAATAATAGGTTATGTAAATAAATATGGTAGAGATG
ACAAAAAAACCGCTTTTAAATATTCTTTATTCTTTTCTTTAGGTATAATAATTACATTTACTTCCTTAGGTATAATTTCT
TCTTTAGTAGGGAAATTTTTTACTTCTGGTGGTAAGCTATGGTATTTATTATTAGGAGTTGCAATGATTTTTGTAGGATT
ACAACTTATAGGGGTAATAGAATCTAAAAATAAGGCATGTAAAGTGCCTAAAAAGCGAAAGGGACTACTTGGTGCATTTT
TTTTAGGAATATTAGGTGGAGTTTTATCCTCACCTTGTTCTACACCTATATTAATAGCTATACTAGCTTTTGTAGGAAGT
AAAGGTAATATATTATTAGGATTTTTAATGTTACTTTTATACTCTATAGGTCATTGTTTTGTAATAATCTTATCAGGAAC
TTCACTGGGTTTTGTTGAATCTTTAAGTGAATCTTCTAAAGCGAACAAAATAAATAATATATTAAAAATAATATTAGGAA
TAATTATATTAGCTATGGGGCTTTATCTAATATATATAGGAATATAA

Upstream 100 bases:

>100_bases
GTATTTTTGGACAAAGAGGGAAAGGTATTTTTTAGACATGAGGGTATGCTTACAAAAGAAGAAATTGTAGATATATTAAA
TAAAATGGGTGTAAAATAAT

Downstream 100 bases:

>100_bases
AATGGAACCTGGATTTTTTAATCTAGGTTCCATTTTATATTAGTTAAAGTTTAAATATAGATACACTTTCCTTTAAATTT
TCTACCATACTAACTAACTT

Product: putative cytochrome c-type biogenesis protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MNEIITKAVSLMGNNVLLALLISFLGGIISSFSPCILSSLPLIIGYVNKYGRDDKKTAFKYSLFFSLGIIITFTSLGIIS
SLVGKFFTSGGKLWYLLLGVAMIFVGLQLIGVIESKNKACKVPKKRKGLLGAFFLGILGGVLSSPCSTPILIAILAFVGS
KGNILLGFLMLLLYSIGHCFVIILSGTSLGFVESLSESSKANKINNILKIILGIIILAMGLYLIYIGI

Sequences:

>Translated_228_residues
MNEIITKAVSLMGNNVLLALLISFLGGIISSFSPCILSSLPLIIGYVNKYGRDDKKTAFKYSLFFSLGIIITFTSLGIIS
SLVGKFFTSGGKLWYLLLGVAMIFVGLQLIGVIESKNKACKVPKKRKGLLGAFFLGILGGVLSSPCSTPILIAILAFVGS
KGNILLGFLMLLLYSIGHCFVIILSGTSLGFVESLSESSKANKINNILKIILGIIILAMGLYLIYIGI
>Mature_228_residues
MNEIITKAVSLMGNNVLLALLISFLGGIISSFSPCILSSLPLIIGYVNKYGRDDKKTAFKYSLFFSLGIIITFTSLGIIS
SLVGKFFTSGGKLWYLLLGVAMIFVGLQLIGVIESKNKACKVPKKRKGLLGAFFLGILGGVLSSPCSTPILIAILAFVGS
KGNILLGFLMLLLYSIGHCFVIILSGTSLGFVESLSESSKANKINNILKIILGIIILAMGLYLIYIGI

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=224, Percent_Identity=28.125, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 24338; Mature: 24338

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEIITKAVSLMGNNVLLALLISFLGGIISSFSPCILSSLPLIIGYVNKYGRDDKKTAFK
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
YSLFFSLGIIITFTSLGIISSLVGKFFTSGGKLWYLLLGVAMIFVGLQLIGVIESKNKAC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KVPKKRKGLLGAFFLGILGGVLSSPCSTPILIAILAFVGSKGNILLGFLMLLLYSIGHCF
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VIILSGTSLGFVESLSESSKANKINNILKIILGIIILAMGLYLIYIGI
HHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNEIITKAVSLMGNNVLLALLISFLGGIISSFSPCILSSLPLIIGYVNKYGRDDKKTAFK
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
YSLFFSLGIIITFTSLGIISSLVGKFFTSGGKLWYLLLGVAMIFVGLQLIGVIESKNKAC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KVPKKRKGLLGAFFLGILGGVLSSPCSTPILIAILAFVGSKGNILLGFLMLLLYSIGHCF
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VIILSGTSLGFVESLSESSKANKINNILKIILGIIILAMGLYLIYIGI
HHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA