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The map label for this gene is acoR [H]

Identifier: 226948955

GI number: 226948955

Start: 1908931

End: 1910883

Strand: Direct

Name: acoR [H]

Synonym: CLM_1869

Alternate gene names: 226948955

Gene position: 1908931-1910883 (Clockwise)

Preceding gene: 226948954

Following gene: 226948956

Centisome position: 45.94

GC content: 28.16

Gene sequence:

>1953_bases
ATGATTAATATATTAGAGGTAGAAAAACAAAGGGAAAATTTCATTAAAAATAATGATATACCGAAAAGTGTAAGACCTGA
GATATTAAATTCATGGATAAGATGTAAAAACTATAATGTAGATACTAATAATGGACAAGGTAAAGAATTACCTAAAGAGG
AATTTGAAAAAATACTATATGAAAAAAGAGATCTTATTCAAATAGCTATACCTGCTATGATTGATTTATACAATGTAGTA
AAGGATACAAACTATTCCATTATTTTAGCGGATGAAAATGCAGTAATTCTTGAAGTTATAGGAAACGAAGAAATAATGAA
TAAAAATATGGAATTGCATTTTTTAAAAGGATGCAAATGGATGGAAAAGGATGTAGGTACTAATGCCATAGGAACTAGTA
TTTATTTAGACAAGCCAATACAGACAATAGGAGCGGAACATTATTGTAAAAGGCAACATGGATGGACTTGTTCTGCGGCG
CCTATACATGATGAAAAAGGAAAAATTATAGGTGTTATAGATTTATCTGGAGATTTTTATGATTATCAAATTCATACCCT
TGGGATAGTAGTTGAGGCAGCAAAAACTATAGAAAAGCAATTTGCCATAGTTCAGCACAGAAAGTGGGTAGAGGTTGCAT
TTAGCTCTATTGAGGATGGTATTTTGGTTATAGACAAAGATTTTTATGTTAAAGATTTCAATAAAAAACTCTGTGAAATT
CTACAGGTGTCAGAGGAAAAAGTTAATAGATTAGATATAAAATTACTTTTAAAAGATATCATAAAGGATGAAAATAACTT
TAGTAATAATAGAATTAACTATAAAGAGGCTAATTTATATTTAGAAAATCGTAAATTAGAGTGCAATATAAATGTTTCTC
CTGTAAAACTAGAAAGTAAGTATATTGGATATGTTATACTGGTTAAAAAAATTGATAGCATTAGAAATGTGGTTAGAAAA
ATAGCGGGCTTTTCATCTAAATATACCTTTGAAAGCATAATAACTAATAATGAAAGGATGTTATCCGTAATTGAGGAGGC
TAAAAAAATTGCTGAAAATGAATGCTCAGTGTTAATTACTGGAGAGAGTGGAACTGGTAAAGAATTGTTTGCTCATTCAA
TTCATAACTCTAGTAATCGATGTAAAGGTCCCTTTATAGCAATAAACTGTGCGGCTCTTCCAAAGGACTTAGTTGAAAGC
GAACTTTTTGGATACGAAAAATCTGCTTTTACAGGAGCATCAAAGGAGGGGAATCCTGGAAAGTTTGAATTAGCAAATAG
AGGTACAATTTTTCTAGATGAAATTGGGGAATTGCCATTAGAAATTCAATCTAAGCTTTTAAGAGTTTTAGATAACCATA
CAATAACAAGAATAGGTGGAAATTTTGAAAGAAAATTAGATGTAAGGGTTATAGCTGCAACAAATAGAAATTTAAATGAA
GAAATTAATAAAAATAATTTTAGAAGTGATTTATATTATAGATTAAATGTATTTAATGTAAGATTAATTCCCTTAAGGGA
AAGACCAGAAGATATTGAATTATGTGCAGACTATTTTCTTCAAAGATTAAATGATAAAAACCAGAGAATGAATAAATCTT
TTGATAAAGATTTTATAAATTTAATTAAAGACTACAATTGGCCAGGAAATGTGAGAGAGCTCGAAAATGTAATTCAAAGA
GCATATTATTTATCTAAGGATGAAATTATTAATTATTCTTTTATTCCAGAGTATATAAATGGAAATATGAAAGAAGAGGA
AATTAAAAATAAGAAAGAAAAATCTAAACCACCAACCCTTGAAGAAATGGAAAGAAAGCTTATTATACAAGCTTTAAAGT
ATTGTAATGGAAACGTTATTAATGCTAGTAAGATTATAGGAATAGGTAAATCAACTTTATATAGAAAAATAGAAAAGTAT
AAATTAGAGGAAGTTTCAAAATGGGAAAAATAA

Upstream 100 bases:

>100_bases
TTTAAGTATTAATTTAAAAAAGAAAAGAATATTTATGTTGATAAATTTAAATTGTTTTAATAAATTTTTGCAAGAATTAT
TTATTATGTAGGTGATAACT

Downstream 100 bases:

>100_bases
TTAATAATTCCCATTTTGAAATAAGTATTTTCCCAAAATGAAACTTTAAAAATAAATAATCTTTAGAAGCCTTGCAAATG
CAAGGCTTTTTCTTTTGGCA

Product: aco operon transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 650; Mature: 650

Protein sequence:

>650_residues
MINILEVEKQRENFIKNNDIPKSVRPEILNSWIRCKNYNVDTNNGQGKELPKEEFEKILYEKRDLIQIAIPAMIDLYNVV
KDTNYSIILADENAVILEVIGNEEIMNKNMELHFLKGCKWMEKDVGTNAIGTSIYLDKPIQTIGAEHYCKRQHGWTCSAA
PIHDEKGKIIGVIDLSGDFYDYQIHTLGIVVEAAKTIEKQFAIVQHRKWVEVAFSSIEDGILVIDKDFYVKDFNKKLCEI
LQVSEEKVNRLDIKLLLKDIIKDENNFSNNRINYKEANLYLENRKLECNINVSPVKLESKYIGYVILVKKIDSIRNVVRK
IAGFSSKYTFESIITNNERMLSVIEEAKKIAENECSVLITGESGTGKELFAHSIHNSSNRCKGPFIAINCAALPKDLVES
ELFGYEKSAFTGASKEGNPGKFELANRGTIFLDEIGELPLEIQSKLLRVLDNHTITRIGGNFERKLDVRVIAATNRNLNE
EINKNNFRSDLYYRLNVFNVRLIPLRERPEDIELCADYFLQRLNDKNQRMNKSFDKDFINLIKDYNWPGNVRELENVIQR
AYYLSKDEIINYSFIPEYINGNMKEEEIKNKKEKSKPPTLEEMERKLIIQALKYCNGNVINASKIIGIGKSTLYRKIEKY
KLEEVSKWEK

Sequences:

>Translated_650_residues
MINILEVEKQRENFIKNNDIPKSVRPEILNSWIRCKNYNVDTNNGQGKELPKEEFEKILYEKRDLIQIAIPAMIDLYNVV
KDTNYSIILADENAVILEVIGNEEIMNKNMELHFLKGCKWMEKDVGTNAIGTSIYLDKPIQTIGAEHYCKRQHGWTCSAA
PIHDEKGKIIGVIDLSGDFYDYQIHTLGIVVEAAKTIEKQFAIVQHRKWVEVAFSSIEDGILVIDKDFYVKDFNKKLCEI
LQVSEEKVNRLDIKLLLKDIIKDENNFSNNRINYKEANLYLENRKLECNINVSPVKLESKYIGYVILVKKIDSIRNVVRK
IAGFSSKYTFESIITNNERMLSVIEEAKKIAENECSVLITGESGTGKELFAHSIHNSSNRCKGPFIAINCAALPKDLVES
ELFGYEKSAFTGASKEGNPGKFELANRGTIFLDEIGELPLEIQSKLLRVLDNHTITRIGGNFERKLDVRVIAATNRNLNE
EINKNNFRSDLYYRLNVFNVRLIPLRERPEDIELCADYFLQRLNDKNQRMNKSFDKDFINLIKDYNWPGNVRELENVIQR
AYYLSKDEIINYSFIPEYINGNMKEEEIKNKKEKSKPPTLEEMERKLIIQALKYCNGNVINASKIIGIGKSTLYRKIEKY
KLEEVSKWEK
>Mature_650_residues
MINILEVEKQRENFIKNNDIPKSVRPEILNSWIRCKNYNVDTNNGQGKELPKEEFEKILYEKRDLIQIAIPAMIDLYNVV
KDTNYSIILADENAVILEVIGNEEIMNKNMELHFLKGCKWMEKDVGTNAIGTSIYLDKPIQTIGAEHYCKRQHGWTCSAA
PIHDEKGKIIGVIDLSGDFYDYQIHTLGIVVEAAKTIEKQFAIVQHRKWVEVAFSSIEDGILVIDKDFYVKDFNKKLCEI
LQVSEEKVNRLDIKLLLKDIIKDENNFSNNRINYKEANLYLENRKLECNINVSPVKLESKYIGYVILVKKIDSIRNVVRK
IAGFSSKYTFESIITNNERMLSVIEEAKKIAENECSVLITGESGTGKELFAHSIHNSSNRCKGPFIAINCAALPKDLVES
ELFGYEKSAFTGASKEGNPGKFELANRGTIFLDEIGELPLEIQSKLLRVLDNHTITRIGGNFERKLDVRVIAATNRNLNE
EINKNNFRSDLYYRLNVFNVRLIPLRERPEDIELCADYFLQRLNDKNQRMNKSFDKDFINLIKDYNWPGNVRELENVIQR
AYYLSKDEIINYSFIPEYINGNMKEEEIKNKKEKSKPPTLEEMERKLIIQALKYCNGNVINASKIIGIGKSTLYRKIEKY
KLEEVSKWEK

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=338, Percent_Identity=42.603550295858, Blast_Score=281, Evalue=6e-77,
Organism=Escherichia coli, GI1789233, Length=304, Percent_Identity=43.75, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI1789087, Length=323, Percent_Identity=42.7244582043344, Blast_Score=252, Evalue=4e-68,
Organism=Escherichia coli, GI87082117, Length=317, Percent_Identity=41.9558359621451, Blast_Score=252, Evalue=5e-68,
Organism=Escherichia coli, GI1790437, Length=308, Percent_Identity=42.2077922077922, Blast_Score=249, Evalue=4e-67,
Organism=Escherichia coli, GI1788905, Length=350, Percent_Identity=36.5714285714286, Blast_Score=248, Evalue=1e-66,
Organism=Escherichia coli, GI1790299, Length=335, Percent_Identity=39.1044776119403, Blast_Score=242, Evalue=5e-65,
Organism=Escherichia coli, GI87081858, Length=641, Percent_Identity=25.1170046801872, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI1786524, Length=340, Percent_Identity=36.1764705882353, Blast_Score=226, Evalue=4e-60,
Organism=Escherichia coli, GI87082152, Length=314, Percent_Identity=40.4458598726115, Blast_Score=224, Evalue=2e-59,
Organism=Escherichia coli, GI1787583, Length=367, Percent_Identity=34.6049046321526, Blast_Score=219, Evalue=6e-58,
Organism=Escherichia coli, GI87081872, Length=225, Percent_Identity=45.3333333333333, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1789828, Length=280, Percent_Identity=31.7857142857143, Blast_Score=138, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 75164; Mature: 75164

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINILEVEKQRENFIKNNDIPKSVRPEILNSWIRCKNYNVDTNNGQGKELPKEEFEKILY
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
EKRDLIQIAIPAMIDLYNVVKDTNYSIILADENAVILEVIGNEEIMNKNMELHFLKGCKW
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEECCHHHHCCCCEEEEECCCCH
MEKDVGTNAIGTSIYLDKPIQTIGAEHYCKRQHGWTCSAAPIHDEKGKIIGVIDLSGDFY
HHHHCCCCCCCCEEEECCCHHHHCHHHHHHHCCCCEECCCCCCCCCCCEEEEEECCCCEE
DYQIHTLGIVVEAAKTIEKQFAIVQHRKWVEVAFSSIEDGILVIDKDFYVKDFNKKLCEI
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHH
LQVSEEKVNRLDIKLLLKDIIKDENNFSNNRINYKEANLYLENRKLECNINVSPVKLESK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCEEEEEECCCEEEECCC
YIGYVILVKKIDSIRNVVRKIAGFSSKYTFESIITNNERMLSVIEEAKKIAENECSVLIT
CCEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEE
GESGTGKELFAHSIHNSSNRCKGPFIAINCAALPKDLVESELFGYEKSAFTGASKEGNPG
CCCCCCHHHHHHHHCCCCCCCCCCEEEEEEHHCCHHHHHHHHHCCCHHHCCCCCCCCCCC
KFELANRGTIFLDEIGELPLEIQSKLLRVLDNHTITRIGGNFERKLDVRVIAATNRNLNE
EEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEEEECCCCCHH
EINKNNFRSDLYYRLNVFNVRLIPLRERPEDIELCADYFLQRLNDKNQRMNKSFDKDFIN
HHCCCCCCCCEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LIKDYNWPGNVRELENVIQRAYYLSKDEIINYSFIPEYINGNMKEEEIKNKKEKSKPPTL
HHHCCCCCCCHHHHHHHHHHHHHCCHHHEEEEEECHHHHCCCCCHHHHHHHHHCCCCCCH
EEMERKLIIQALKYCNGNVINASKIIGIGKSTLYRKIEKYKLEEVSKWEK
HHHHHHHHHHHHHHCCCCEEEHHHEEECCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MINILEVEKQRENFIKNNDIPKSVRPEILNSWIRCKNYNVDTNNGQGKELPKEEFEKILY
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
EKRDLIQIAIPAMIDLYNVVKDTNYSIILADENAVILEVIGNEEIMNKNMELHFLKGCKW
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEECCHHHHCCCCEEEEECCCCH
MEKDVGTNAIGTSIYLDKPIQTIGAEHYCKRQHGWTCSAAPIHDEKGKIIGVIDLSGDFY
HHHHCCCCCCCCEEEECCCHHHHCHHHHHHHCCCCEECCCCCCCCCCCEEEEEECCCCEE
DYQIHTLGIVVEAAKTIEKQFAIVQHRKWVEVAFSSIEDGILVIDKDFYVKDFNKKLCEI
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHH
LQVSEEKVNRLDIKLLLKDIIKDENNFSNNRINYKEANLYLENRKLECNINVSPVKLESK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCEEEEEECCCEEEECCC
YIGYVILVKKIDSIRNVVRKIAGFSSKYTFESIITNNERMLSVIEEAKKIAENECSVLIT
CCEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEE
GESGTGKELFAHSIHNSSNRCKGPFIAINCAALPKDLVESELFGYEKSAFTGASKEGNPG
CCCCCCHHHHHHHHCCCCCCCCCCEEEEEEHHCCHHHHHHHHHCCCHHHCCCCCCCCCCC
KFELANRGTIFLDEIGELPLEIQSKLLRVLDNHTITRIGGNFERKLDVRVIAATNRNLNE
EEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEEEECCCCCHH
EINKNNFRSDLYYRLNVFNVRLIPLRERPEDIELCADYFLQRLNDKNQRMNKSFDKDFIN
HHCCCCCCCCEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LIKDYNWPGNVRELENVIQRAYYLSKDEIINYSFIPEYINGNMKEEEIKNKKEKSKPPTL
HHHCCCCCCCHHHHHHHHHHHHHCCHHHEEEEEECHHHHCCCCCHHHHHHHHHCCCCCCH
EEMERKLIIQALKYCNGNVINASKIIGIGKSTLYRKIEKYKLEEVSKWEK
HHHHHHHHHHHHHHCCCCEEEHHHEEECCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA