Click here to switch to the map view.

The map label for this gene is arcD [H]

Identifier: 226948919

GI number: 226948919

Start: 1859717

End: 1861135

Strand: Direct

Name: arcD [H]

Synonym: CLM_1829

Alternate gene names: 226948919

Gene position: 1859717-1861135 (Clockwise)

Preceding gene: 226948918

Following gene: 226948921

Centisome position: 44.76

GC content: 32.84

Gene sequence:

>1419_bases
ATGGGAACACAAGATAAAAAATTAGGTCTTGGACTTTTGATTACTCTCGGTATAGGCTCTATGATAGGCGGTGGGATTTT
TAATAGTCCCACGGACTTAATAACAAAAGCTAATCCACAAGCAGCTCTAATTGCTTGGATAATAGGTGGATTTGGAATTA
TATGCTTAGCACTAGTATTCCAATTTCTTGCTAATAAAAAACCAGATTTAAAAGGTGGAATTTATTCATATGCACAGGAT
GGATTTGGAGACTTTATGGGTTTCAACTCAGCTTGGGGATATTGGCTTTCTGCTTGGCTTGGAAATATTGCTTTTATAGT
ATTAATGTTTAAAACCATAAACAGTTTATTAGGACCAGGACGTGAATTAAAGCCAATAGTGTCTTTTATAGCAGCATCCT
TATTATTATGGTCTGTACATTACATCCAAACAAAGGGGACAAAGAATGCAGGGATCATAAATGCAGTTGTAACTATAGGT
AAGTTATTACCGTTAACATTAGTTGTTATATTGGGTATATTCATATTTAAGCCAGAACTATTTACAGTTTCAAACTGGAG
TACAGTACTTGCAAGTTCTGGGAAAGCAACATCTACATTTAAACAAGTTAATGGTGCCATGGGAACTATAATTTGGTGCT
TTATCGGTGTAGAAGCATCTGTAGTTCTTTCAGAAAAGGCAGAATCACAGGCTATAGTTGGAAAAGCAACAGTAATTAGT
TTATTAATTACATTACTTATTTATGTTTCAATATCATTACTTGCAATGGGCATTATTCCAGCTAAGGATCTTGCAGTATC
AGGTACTCCTTTAGCAGATGTCTTATCAAAAACGGTCTTCGGAGGAGCAGGAGCTGTAATAGTTAAATTAGGTCTTATAA
TATCATTGTTTGGGGCATTAATAAGTTGGGTAATGCTTGCAGCAGAGATACCATATGTAGCAGCTAAAGATGGAGTTATG
CCAAAATGGTTTGCTAAAGAGAACGCAGCAGGAGTTGCAATAAATTCATTAACATTTACAAATATTATAACTCAAGTATT
TTTATGTACATTACTTTCAGATAAATTACAATCAGCTTATAGTTTAGTATTTGCTATAGCAACTACTTGTATGTTAATTC
CTTATACTTTATCATCATTTTATGCTATAAAGGTATGTAATGAAGAAAAGATAAATGGAAAAGATAAGATAATAGCAATC
TTAGCTTCCATATATACAATATATGGTATATATGCAGGTGGAATTAAATACTTTGCTCTTGCATTTATAATGTACGCCTT
TGGAGTAATAGTTTTCAATAAAGCCAAGAAAGAAAAGAAACAAAAGTATACATCAATTGAGAAGATCGGTACAGCTGTAG
TTGTATTTGTAGGGGTAGTTATGATAGTTTTACTTTCAATAGGAAAAATATCACTATAA

Upstream 100 bases:

>100_bases
CAATTATTTAGATATGTTAACATAATTTATATAATTATGTTAACATAATCTATATAATTTTGTATAATAATCTATATACA
TTGAGAAAAGAGGTTTGAAA

Downstream 100 bases:

>100_bases
TATTTAGATATAACTTGTGTAATATATTTTATATAAAGTAAAATATAAAAATTAAAACCGTCTCTATACTAAATAGGTTA
TTTATAAACTATGATTAAAA

Product: arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MGTQDKKLGLGLLITLGIGSMIGGGIFNSPTDLITKANPQAALIAWIIGGFGIICLALVFQFLANKKPDLKGGIYSYAQD
GFGDFMGFNSAWGYWLSAWLGNIAFIVLMFKTINSLLGPGRELKPIVSFIAASLLLWSVHYIQTKGTKNAGIINAVVTIG
KLLPLTLVVILGIFIFKPELFTVSNWSTVLASSGKATSTFKQVNGAMGTIIWCFIGVEASVVLSEKAESQAIVGKATVIS
LLITLLIYVSISLLAMGIIPAKDLAVSGTPLADVLSKTVFGGAGAVIVKLGLIISLFGALISWVMLAAEIPYVAAKDGVM
PKWFAKENAAGVAINSLTFTNIITQVFLCTLLSDKLQSAYSLVFAIATTCMLIPYTLSSFYAIKVCNEEKINGKDKIIAI
LASIYTIYGIYAGGIKYFALAFIMYAFGVIVFNKAKKEKKQKYTSIEKIGTAVVVFVGVVMIVLLSIGKISL

Sequences:

>Translated_472_residues
MGTQDKKLGLGLLITLGIGSMIGGGIFNSPTDLITKANPQAALIAWIIGGFGIICLALVFQFLANKKPDLKGGIYSYAQD
GFGDFMGFNSAWGYWLSAWLGNIAFIVLMFKTINSLLGPGRELKPIVSFIAASLLLWSVHYIQTKGTKNAGIINAVVTIG
KLLPLTLVVILGIFIFKPELFTVSNWSTVLASSGKATSTFKQVNGAMGTIIWCFIGVEASVVLSEKAESQAIVGKATVIS
LLITLLIYVSISLLAMGIIPAKDLAVSGTPLADVLSKTVFGGAGAVIVKLGLIISLFGALISWVMLAAEIPYVAAKDGVM
PKWFAKENAAGVAINSLTFTNIITQVFLCTLLSDKLQSAYSLVFAIATTCMLIPYTLSSFYAIKVCNEEKINGKDKIIAI
LASIYTIYGIYAGGIKYFALAFIMYAFGVIVFNKAKKEKKQKYTSIEKIGTAVVVFVGVVMIVLLSIGKISL
>Mature_471_residues
GTQDKKLGLGLLITLGIGSMIGGGIFNSPTDLITKANPQAALIAWIIGGFGIICLALVFQFLANKKPDLKGGIYSYAQDG
FGDFMGFNSAWGYWLSAWLGNIAFIVLMFKTINSLLGPGRELKPIVSFIAASLLLWSVHYIQTKGTKNAGIINAVVTIGK
LLPLTLVVILGIFIFKPELFTVSNWSTVLASSGKATSTFKQVNGAMGTIIWCFIGVEASVVLSEKAESQAIVGKATVISL
LITLLIYVSISLLAMGIIPAKDLAVSGTPLADVLSKTVFGGAGAVIVKLGLIISLFGALISWVMLAAEIPYVAAKDGVMP
KWFAKENAAGVAINSLTFTNIITQVFLCTLLSDKLQSAYSLVFAIATTCMLIPYTLSSFYAIKVCNEEKINGKDKIIAIL
ASIYTIYGIYAGGIKYFALAFIMYAFGVIVFNKAKKEKKQKYTSIEKIGTAVVVFVGVVMIVLLSIGKISL

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=467, Percent_Identity=35.117773019272, Blast_Score=274, Evalue=9e-75,
Organism=Escherichia coli, GI2367353, Length=453, Percent_Identity=26.0485651214128, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1786908, Length=418, Percent_Identity=24.4019138755981, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87082250, Length=344, Percent_Identity=27.3255813953488, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1790575, Length=469, Percent_Identity=22.6012793176972, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50321; Mature: 50190

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTQDKKLGLGLLITLGIGSMIGGGIFNSPTDLITKANPQAALIAWIIGGFGIICLALVF
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
QFLANKKPDLKGGIYSYAQDGFGDFMGFNSAWGYWLSAWLGNIAFIVLMFKTINSLLGPG
HHHCCCCCCCCCCHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RELKPIVSFIAASLLLWSVHYIQTKGTKNAGIINAVVTIGKLLPLTLVVILGIFIFKPEL
CHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
FTVSNWSTVLASSGKATSTFKQVNGAMGTIIWCFIGVEASVVLSEKAESQAIVGKATVIS
EEECCCHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCCHHEEEHHHCCCHHHHHHHHHHH
LLITLLIYVSISLLAMGIIPAKDLAVSGTPLADVLSKTVFGGAGAVIVKLGLIISLFGAL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ISWVMLAAEIPYVAAKDGVMPKWFAKENAAGVAINSLTFTNIITQVFLCTLLSDKLQSAY
HHHHHHHHHCCCEECCCCCCCCHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVFAIATTCMLIPYTLSSFYAIKVCNEEKINGKDKIIAILASIYTIYGIYAGGIKYFAL
HHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFIMYAFGVIVFNKAKKEKKQKYTSIEKIGTAVVVFVGVVMIVLLSIGKISL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GTQDKKLGLGLLITLGIGSMIGGGIFNSPTDLITKANPQAALIAWIIGGFGIICLALVF
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
QFLANKKPDLKGGIYSYAQDGFGDFMGFNSAWGYWLSAWLGNIAFIVLMFKTINSLLGPG
HHHCCCCCCCCCCHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RELKPIVSFIAASLLLWSVHYIQTKGTKNAGIINAVVTIGKLLPLTLVVILGIFIFKPEL
CHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
FTVSNWSTVLASSGKATSTFKQVNGAMGTIIWCFIGVEASVVLSEKAESQAIVGKATVIS
EEECCCHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCCHHEEEHHHCCCHHHHHHHHHHH
LLITLLIYVSISLLAMGIIPAKDLAVSGTPLADVLSKTVFGGAGAVIVKLGLIISLFGAL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ISWVMLAAEIPYVAAKDGVMPKWFAKENAAGVAINSLTFTNIITQVFLCTLLSDKLQSAY
HHHHHHHHHCCCEECCCCCCCCHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVFAIATTCMLIPYTLSSFYAIKVCNEEKINGKDKIIAILASIYTIYGIYAGGIKYFAL
HHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFIMYAFGVIVFNKAKKEKKQKYTSIEKIGTAVVVFVGVVMIVLLSIGKISL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9053381; 11792842 [H]