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The map label for this gene is hisE [H]

Identifier: 226948905

GI number: 226948905

Start: 1845687

End: 1846019

Strand: Direct

Name: hisE [H]

Synonym: CLM_1815

Alternate gene names: 226948905

Gene position: 1845687-1846019 (Clockwise)

Preceding gene: 226948904

Following gene: 226948906

Centisome position: 44.42

GC content: 23.72

Gene sequence:

>333_bases
ATGAATAAAAATAATGTTATAGATAGTTTATTTAATATAATAGAGGACAGAAAAGATAAGCCTATAGAAGGTTCTTATAC
TGGATATTTATTTGAAAAAGGATTGGATAAAATATTAAAAAAGGTTGGAGAAGAAAGTTCAGAGGTAATTATAGCTGCTA
AAAATGAAGACGAAGAGGAACTGATAAAAGAAATATGTGATTTAACCTATCACATAATGGTTTTAATGGTAGAAAAACAA
ATAAAATTAGATGGTATAGAAAAAGAATTAGAAAAGAGAAGAGAAAAAATATGCAATAAAAAAAATGAAAGAAAAACAAT
AGAGAAATTATAA

Upstream 100 bases:

>100_bases
TCACATATAGGAATTGATGTTATAAAATGGATAGGGGGAAGGATGTGAGTATTTGGTGGTTTGATGTAATTTATAAACAT
CTGATCACTAAGGACAAATT

Downstream 100 bases:

>100_bases
AAATAGGAAGAGTCAGTATAATTATTGTAATTTGAACTATCTTTATTAATATATTAAAATAAATGTATATTTATAAATTT
CAAATAATGAATAAATAAAA

Product: phosphoribosyl-ATP pyrophosphatase

Products: NA

Alternate protein names: PRA-PH [H]

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
MNKNNVIDSLFNIIEDRKDKPIEGSYTGYLFEKGLDKILKKVGEESSEVIIAAKNEDEEELIKEICDLTYHIMVLMVEKQ
IKLDGIEKELEKRREKICNKKNERKTIEKL

Sequences:

>Translated_110_residues
MNKNNVIDSLFNIIEDRKDKPIEGSYTGYLFEKGLDKILKKVGEESSEVIIAAKNEDEEELIKEICDLTYHIMVLMVEKQ
IKLDGIEKELEKRREKICNKKNERKTIEKL
>Mature_110_residues
MNKNNVIDSLFNIIEDRKDKPIEGSYTGYLFEKGLDKILKKVGEESSEVIIAAKNEDEEELIKEICDLTYHIMVLMVEKQ
IKLDGIEKELEKRREKICNKKNERKTIEKL

Specific function: Histidine biosynthesis; second step. Histidine biosynthesis; third step. [C]

COG id: COG0140

COG function: function code E; Phosphoribosyl-ATP pyrophosphohydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-PH family [H]

Homologues:

Organism=Escherichia coli, GI2367128, Length=83, Percent_Identity=37.3493975903614, Blast_Score=61, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008179
- InterPro:   IPR021130 [H]

Pfam domain/function: PF01503 PRA-PH [H]

EC number: =3.6.1.31 [H]

Molecular weight: Translated: 12915; Mature: 12915

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNNVIDSLFNIIEDRKDKPIEGSYTGYLFEKGLDKILKKVGEESSEVIIAAKNEDEEE
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHH
LIKEICDLTYHIMVLMVEKQIKLDGIEKELEKRREKICNKKNERKTIEKL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure
MNKNNVIDSLFNIIEDRKDKPIEGSYTGYLFEKGLDKILKKVGEESSEVIIAAKNEDEEE
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHH
LIKEICDLTYHIMVLMVEKQIKLDGIEKELEKRREKICNKKNERKTIEKL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA