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The map label for this gene is queC [H]

Identifier: 226948888

GI number: 226948888

Start: 1829615

End: 1830274

Strand: Direct

Name: queC [H]

Synonym: CLM_1798

Alternate gene names: 226948888

Gene position: 1829615-1830274 (Clockwise)

Preceding gene: 226948887

Following gene: 226948889

Centisome position: 44.03

GC content: 29.09

Gene sequence:

>660_bases
ATGAATAAGGAAAAAGCAATAGTAGTATTTAGTGGTGGACAAGATAGTACAACCTGTTTGTTTTGGGCAAAGAAAAAATA
TAAAGAAGTTATAGCAGTATCCTTTGATTATAATCAAAAACATAAATTAGAGTTAGATTGTGCAAAGGATATATGTAAAA
AATATAATATTGAACATCATATTTTAGATTTAAATTTGTTAAATCAATTAGCACCAAATTCACTAACTAGGCAGGATATA
ACTGTTGATAAAAGCGCGCCAAAAGAGGGAGTACCTAATTCCTTTGTAGATGGAAGAAATTTATTGTTTTTAAGCTTTGT
CGCAGTATTTGCAAAACAAAAAGGAATAAACACTATTATAACTGGCGTGTCACAAAGTGATTTTAGTGGATATCCAGATT
GTAGAGATGTATTTATAAAATCTTTAAATGTTACATTAAATTTAGCTATGGATTATGAATTTGAAATCATTACACCACTA
ATGTGGATTAATAAAGCAGAAACGTGGAAAATGGCTTATGATTTAGGAGTTCTTGATATCGTTAAAGAAGAAACCTTAAC
ATGCTACAATGGAATAAAAGCAGATGGATGTGGAGAATGTCCAGCTTGTAAATTAAGAAAAAAGGGATATTGGGAGTTTG
AAAAATATTTAATGAATTAG

Upstream 100 bases:

>100_bases
AACAGCTTATATAAAGAGAGTGTATTAAGGAAGCATAACTATAACAAAGATCTTTGTAGATTGTAGGATGATAATAAAAT
AATAAAGGGATGTGTAGTAA

Downstream 100 bases:

>100_bases
AGTTAATTTAGGAGGACTAGTATGCTAAGTACTAGTTTTTTTATTGTGAAATTATGGGGAATTATGGTATAATTAGTTCA
GGATTAAGCAAGTTATTGTA

Product: ExsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MNKEKAIVVFSGGQDSTTCLFWAKKKYKEVIAVSFDYNQKHKLELDCAKDICKKYNIEHHILDLNLLNQLAPNSLTRQDI
TVDKSAPKEGVPNSFVDGRNLLFLSFVAVFAKQKGINTIITGVSQSDFSGYPDCRDVFIKSLNVTLNLAMDYEFEIITPL
MWINKAETWKMAYDLGVLDIVKEETLTCYNGIKADGCGECPACKLRKKGYWEFEKYLMN

Sequences:

>Translated_219_residues
MNKEKAIVVFSGGQDSTTCLFWAKKKYKEVIAVSFDYNQKHKLELDCAKDICKKYNIEHHILDLNLLNQLAPNSLTRQDI
TVDKSAPKEGVPNSFVDGRNLLFLSFVAVFAKQKGINTIITGVSQSDFSGYPDCRDVFIKSLNVTLNLAMDYEFEIITPL
MWINKAETWKMAYDLGVLDIVKEETLTCYNGIKADGCGECPACKLRKKGYWEFEKYLMN
>Mature_219_residues
MNKEKAIVVFSGGQDSTTCLFWAKKKYKEVIAVSFDYNQKHKLELDCAKDICKKYNIEHHILDLNLLNQLAPNSLTRQDI
TVDKSAPKEGVPNSFVDGRNLLFLSFVAVFAKQKGINTIITGVSQSDFSGYPDCRDVFIKSLNVTLNLAMDYEFEIITPL
MWINKAETWKMAYDLGVLDIVKEETLTCYNGIKADGCGECPACKLRKKGYWEFEKYLMN

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=210, Percent_Identity=55.2380952380952, Blast_Score=239, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 24938; Mature: 24938

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKEKAIVVFSGGQDSTTCLFWAKKKYKEVIAVSFDYNQKHKLELDCAKDICKKYNIEHH
CCCCCEEEEEECCCCCEEEEEEEHHHCCEEEEEEECCCCCEEEEHHHHHHHHHHCCCCCE
ILDLNLLNQLAPNSLTRQDITVDKSAPKEGVPNSFVDGRNLLFLSFVAVFAKQKGINTII
EEHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
TGVSQSDFSGYPDCRDVFIKSLNVTLNLAMDYEFEIITPLMWINKAETWKMAYDLGVLDI
ECCCCCCCCCCCCHHHHHHHHCCEEEEEEEECCEEEECHHHHCCCCCCEEEEHHCCHHHH
VKEETLTCYNGIKADGCGECPACKLRKKGYWEFEKYLMN
HHHHHHHHHCCCCCCCCCCCCCCHHCCCCCHHHHHHHCC
>Mature Secondary Structure
MNKEKAIVVFSGGQDSTTCLFWAKKKYKEVIAVSFDYNQKHKLELDCAKDICKKYNIEHH
CCCCCEEEEEECCCCCEEEEEEEHHHCCEEEEEEECCCCCEEEEHHHHHHHHHHCCCCCE
ILDLNLLNQLAPNSLTRQDITVDKSAPKEGVPNSFVDGRNLLFLSFVAVFAKQKGINTII
EEHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
TGVSQSDFSGYPDCRDVFIKSLNVTLNLAMDYEFEIITPLMWINKAETWKMAYDLGVLDI
ECCCCCCCCCCCCHHHHHHHHCCEEEEEEEECCEEEECHHHHCCCCCCEEEEHHCCHHHH
VKEETLTCYNGIKADGCGECPACKLRKKGYWEFEKYLMN
HHHHHHHHHCCCCCCCCCCCCCCHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA