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The map label for this gene is yclF [H]

Identifier: 226948872

GI number: 226948872

Start: 1813039

End: 1814442

Strand: Direct

Name: yclF [H]

Synonym: CLM_1774

Alternate gene names: 226948872

Gene position: 1813039-1814442 (Clockwise)

Preceding gene: 226948871

Following gene: 226948873

Centisome position: 43.63

GC content: 30.63

Gene sequence:

>1404_bases
ATGTCATCAAATGTAAAGGAAAAGACTCATCCAAAGGGATTTTGGTTGATATGTTTTACAATCTTATGGGAAAGATTTAG
TTATTATGGTTTAACATCATTAGTAATATTATATTTTACAGCTAGTATAGCACAGGGTGGCGTTGGGTTATCAACAGCCA
AAGCCACTATGCTTTTTGCTTGGTTTGCTGGCTTAGTTTATTTAGCACCAGTAATTGGTGGTATTTTAGGAGATCGATAC
TTGGGACAACAAAAATGCATAATTATAGGATCTTTTTTAGCAGTAATAGGGGATTTATTTTTATTTTTTAGTACAGGAAG
TATAGGTTCAGTGTATTTTGCTTTATTTATATTAATTGCATCTAATGGTTTCTTTAAAGCGAATTGTGCAAATTTAGTTG
GAGATTTATATCCTAAGGATGCTTCTTCCACTAAGGATGCTGCGTATAATCTATTTTATAGTGCAGTAAATGTAGGTGCA
TTTTTTGCTCCAATAATAACAGGATTAATAGCAGATAATTGGTTTGCAGTGAAAAAAGGAAGTGAAATTGTATCATATGG
ATATAAACAAGTGTTCTTAGTATGTGCAATTGGTATGCTAATAGGAGCTGTTGCATTTACAATGTTAGCACCAAAATATT
TAGGTAATGTAGGCAAATATCCTGCAACTAAAAATACTGAAGGTAAAAAGGTTGAAAATAGACCACTTACAACTCAAGAA
AAAAGAAGATGTACTGCAATGTTTATTATAACTGTATTTGTTATAGTATTTTGGACAGGGTATTTCCAAAGTCAAAACTC
ATTTTTAATATATAGTAGAGATCATGTAAATAGAACTATTGGCGGGTTTGAGATACCTGTAGCATGGCTTACATCACTTA
ATGCTATATTATGTGTATTTTTAGCACCTTTAATAGGTTCCTTTTGGATAAAATTATCTAGAACAAAAAAAGGTGATTTA
ACTATACCTACAAAAATGGGATTAGGAATTTTGCTAATGGGTATTGGATTCTTTATTATGGTATTATCAGTTTTATCTAC
AGGTGGCACTGGAGATGGTGCTGCAAAAGCTAGTCTTGGTTGGATATGTTTAACTTATGTATTTAATACAGTAGGTGAGA
TATGTCTATCACCTATAGGACTTGCAATGTTTAATAAATTATCACCAGATAAATATAAAAATTTCTTTATGGGAATATGG
TATACATCAACTTTCTTTTCAAGTTTAATTTCAGGAAAACTTGCAGCTTTCACAGAAAATATGGGATTTTTATCTGTATT
TAGATTAATTGCTATTTCAATGTTTATAATGGCTGCAATACTATTCCTTATGAGAAATAAGCTTCATCACATGATGACAG
ATGAAGATCTTGAATTAAAAAATTCAGCAAATTTAAATGCTTAA

Upstream 100 bases:

>100_bases
TCTAAAAGGAAAAAAGTATTGTGAAGTTATTGTATGATAATGGTATATATGATAAAATTTTATTATATACAAATATTTAC
AATAGAAAGAAGGGGATTGT

Downstream 100 bases:

>100_bases
TTAAAATAAAAAATACAAGTAAAAGAAACTATTTTTAGTAGATATATGAGTTTTTATAATAAGATATAATTGTTTATACA
TCTAATATAAATATAATTAA

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MSSNVKEKTHPKGFWLICFTILWERFSYYGLTSLVILYFTASIAQGGVGLSTAKATMLFAWFAGLVYLAPVIGGILGDRY
LGQQKCIIIGSFLAVIGDLFLFFSTGSIGSVYFALFILIASNGFFKANCANLVGDLYPKDASSTKDAAYNLFYSAVNVGA
FFAPIITGLIADNWFAVKKGSEIVSYGYKQVFLVCAIGMLIGAVAFTMLAPKYLGNVGKYPATKNTEGKKVENRPLTTQE
KRRCTAMFIITVFVIVFWTGYFQSQNSFLIYSRDHVNRTIGGFEIPVAWLTSLNAILCVFLAPLIGSFWIKLSRTKKGDL
TIPTKMGLGILLMGIGFFIMVLSVLSTGGTGDGAAKASLGWICLTYVFNTVGEICLSPIGLAMFNKLSPDKYKNFFMGIW
YTSTFFSSLISGKLAAFTENMGFLSVFRLIAISMFIMAAILFLMRNKLHHMMTDEDLELKNSANLNA

Sequences:

>Translated_467_residues
MSSNVKEKTHPKGFWLICFTILWERFSYYGLTSLVILYFTASIAQGGVGLSTAKATMLFAWFAGLVYLAPVIGGILGDRY
LGQQKCIIIGSFLAVIGDLFLFFSTGSIGSVYFALFILIASNGFFKANCANLVGDLYPKDASSTKDAAYNLFYSAVNVGA
FFAPIITGLIADNWFAVKKGSEIVSYGYKQVFLVCAIGMLIGAVAFTMLAPKYLGNVGKYPATKNTEGKKVENRPLTTQE
KRRCTAMFIITVFVIVFWTGYFQSQNSFLIYSRDHVNRTIGGFEIPVAWLTSLNAILCVFLAPLIGSFWIKLSRTKKGDL
TIPTKMGLGILLMGIGFFIMVLSVLSTGGTGDGAAKASLGWICLTYVFNTVGEICLSPIGLAMFNKLSPDKYKNFFMGIW
YTSTFFSSLISGKLAAFTENMGFLSVFRLIAISMFIMAAILFLMRNKLHHMMTDEDLELKNSANLNA
>Mature_466_residues
SSNVKEKTHPKGFWLICFTILWERFSYYGLTSLVILYFTASIAQGGVGLSTAKATMLFAWFAGLVYLAPVIGGILGDRYL
GQQKCIIIGSFLAVIGDLFLFFSTGSIGSVYFALFILIASNGFFKANCANLVGDLYPKDASSTKDAAYNLFYSAVNVGAF
FAPIITGLIADNWFAVKKGSEIVSYGYKQVFLVCAIGMLIGAVAFTMLAPKYLGNVGKYPATKNTEGKKVENRPLTTQEK
RRCTAMFIITVFVIVFWTGYFQSQNSFLIYSRDHVNRTIGGFEIPVAWLTSLNAILCVFLAPLIGSFWIKLSRTKKGDLT
IPTKMGLGILLMGIGFFIMVLSVLSTGGTGDGAAKASLGWICLTYVFNTVGEICLSPIGLAMFNKLSPDKYKNFFMGIWY
TSTFFSSLISGKLAAFTENMGFLSVFRLIAISMFIMAAILFLMRNKLHHMMTDEDLELKNSANLNA

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=370, Percent_Identity=23.7837837837838, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1787922, Length=494, Percent_Identity=27.1255060728745, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1789911, Length=503, Percent_Identity=24.8508946322068, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1790572, Length=449, Percent_Identity=26.9487750556793, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1786927, Length=202, Percent_Identity=31.6831683168317, Blast_Score=105, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI71987453, Length=455, Percent_Identity=23.7362637362637, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322946, Length=513, Percent_Identity=23.1968810916179, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 51309; Mature: 51178

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSNVKEKTHPKGFWLICFTILWERFSYYGLTSLVILYFTASIAQGGVGLSTAKATMLFA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH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CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]