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The map label for this gene is aspC [H]

Identifier: 226948294

GI number: 226948294

Start: 1217599

End: 1218888

Strand: Reverse

Name: aspC [H]

Synonym: CLM_1174

Alternate gene names: 226948294

Gene position: 1218888-1217599 (Counterclockwise)

Preceding gene: 226948299

Following gene: 226948290

Centisome position: 29.33

GC content: 28.76

Gene sequence:

>1290_bases
ATGAAAAGAACATTAATAAGTGAATTGAAAAATTTTATAAATGAAAATGTAAATCTTCAAGGATGGATTCATAAAATTAG
GAAATTGAAGAATATAACATTTTTAATAATAAGAGATAGATCAGGATTGATTCAATGTATTGTAGATAATGATAAATTGG
ATTTATCGGAGGTAAAGATAGAATCTATAGTGTCAATGACAGGAGTTGTTAAAGAAAGTACTAATGCTTTAAATCCTTTT
GAAATACAAGTAGAAAATTTAGAAATTATAAATGCTGCTTTAGATAAAGTTCCAATAGAAATAAATAAAGAAAATCTAGA
GATTAATTTAGATACTATGCTTAATAATAGGATATTAAGCTTAAGGCACCCTAAGGTAAATTCAATATTTAAAGTTCAAA
ACTCAATAGTAAATGGATTTAGAGAATTTTTAAATAAAGAAGGATTTACTGAAATTTATACTCCAAAGATTGTATGGGAA
GGAGCTGAAGGTGGTACAGAAGTATTTAAGGTAAAATACTTTGAAAATACTGCTTATTTAGCCCAAAGCCCTCAATTCTA
CAAACAGATGATGGTAGTTGCTGGATTTGAAAGAGTATTTGAAATAGGTCATGCCTATAGGGCAGAAGAGCATAATACTA
ATAGGCATCTAAATGAATATATTAGTATGGACTTGGAAATTGGATTTATAAAAGATGAAAAAGATATTATGGAAGTTGAG
GAAAGGTTATTAAAGTTCATATTAGAAAAACTTAATAAAGAATGTAAGGAATATTTTGACCTACTGGATTCAGAATTACC
AAAAATAGAATCCGAAATACCTAAGATTACATTTAAGGAAGCATTAGATATATTAATTAAGGAATATAATAAAAATAATT
TAACTTGTGACTTAGATCCAGAAGGAGAAAAACTCATATGTAAGTATGCAAAGGAAAAGCTAGATAGTGATTTCATATTT
TTAACTAACTATCCTAGAGAAAAGAGACCAATGTATACCATGCCCCTAGGTAAAGATGGAACTCATAGTTTCGATCTGTT
ATTTAGAGGTATAGAGATTACTACAGGTGGGCAAAGAATTCACGACTATAATATGCTAGTAGATAATATGGAATTTAAAG
GATTAAATCCTAAGGACTATGAGAGTTATTTATCTGCTTTTAAGTATGGAATGCCTAAGCATGGAGGCCTTGCCATTGGA
TTAGAACGACTAACATCAAGACTTCTAGGATTAGAAAATGTTAGAGAAGCTGCATTAATTACAAGAGATAGAACTCGTTT
ACTTCCTTAA

Upstream 100 bases:

>100_bases
CTAATTTTGTATAATCATTGTTAAAAAGGGTGGTACCGCAAATTATTTTGCCCCTTGGGTTTTTACTCAAGGGGCTTATT
TTATTTAGGAGGTAATAAAT

Downstream 100 bases:

>100_bases
AGTTACTCTATTATCACAATTGTCTTCCTAGCTCTTTATAAATTTCAATATCTTATTTATTCATAAGTATCTTAGGGAGG
AACATTGATAATTTACTCCC

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MKRTLISELKNFINENVNLQGWIHKIRKLKNITFLIIRDRSGLIQCIVDNDKLDLSEVKIESIVSMTGVVKESTNALNPF
EIQVENLEIINAALDKVPIEINKENLEINLDTMLNNRILSLRHPKVNSIFKVQNSIVNGFREFLNKEGFTEIYTPKIVWE
GAEGGTEVFKVKYFENTAYLAQSPQFYKQMMVVAGFERVFEIGHAYRAEEHNTNRHLNEYISMDLEIGFIKDEKDIMEVE
ERLLKFILEKLNKECKEYFDLLDSELPKIESEIPKITFKEALDILIKEYNKNNLTCDLDPEGEKLICKYAKEKLDSDFIF
LTNYPREKRPMYTMPLGKDGTHSFDLLFRGIEITTGGQRIHDYNMLVDNMEFKGLNPKDYESYLSAFKYGMPKHGGLAIG
LERLTSRLLGLENVREAALITRDRTRLLP

Sequences:

>Translated_429_residues
MKRTLISELKNFINENVNLQGWIHKIRKLKNITFLIIRDRSGLIQCIVDNDKLDLSEVKIESIVSMTGVVKESTNALNPF
EIQVENLEIINAALDKVPIEINKENLEINLDTMLNNRILSLRHPKVNSIFKVQNSIVNGFREFLNKEGFTEIYTPKIVWE
GAEGGTEVFKVKYFENTAYLAQSPQFYKQMMVVAGFERVFEIGHAYRAEEHNTNRHLNEYISMDLEIGFIKDEKDIMEVE
ERLLKFILEKLNKECKEYFDLLDSELPKIESEIPKITFKEALDILIKEYNKNNLTCDLDPEGEKLICKYAKEKLDSDFIF
LTNYPREKRPMYTMPLGKDGTHSFDLLFRGIEITTGGQRIHDYNMLVDNMEFKGLNPKDYESYLSAFKYGMPKHGGLAIG
LERLTSRLLGLENVREAALITRDRTRLLP
>Mature_429_residues
MKRTLISELKNFINENVNLQGWIHKIRKLKNITFLIIRDRSGLIQCIVDNDKLDLSEVKIESIVSMTGVVKESTNALNPF
EIQVENLEIINAALDKVPIEINKENLEINLDTMLNNRILSLRHPKVNSIFKVQNSIVNGFREFLNKEGFTEIYTPKIVWE
GAEGGTEVFKVKYFENTAYLAQSPQFYKQMMVVAGFERVFEIGHAYRAEEHNTNRHLNEYISMDLEIGFIKDEKDIMEVE
ERLLKFILEKLNKECKEYFDLLDSELPKIESEIPKITFKEALDILIKEYNKNNLTCDLDPEGEKLICKYAKEKLDSDFIF
LTNYPREKRPMYTMPLGKDGTHSFDLLFRGIEITTGGQRIHDYNMLVDNMEFKGLNPKDYESYLSAFKYGMPKHGGLAIG
LERLTSRLLGLENVREAALITRDRTRLLP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI45439306, Length=445, Percent_Identity=34.6067415730337, Blast_Score=266, Evalue=4e-71,
Organism=Homo sapiens, GI4758762, Length=438, Percent_Identity=26.9406392694064, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI226491502, Length=445, Percent_Identity=26.9662921348315, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI40789249, Length=252, Percent_Identity=32.1428571428571, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1787161, Length=452, Percent_Identity=26.5486725663717, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1788173, Length=265, Percent_Identity=29.0566037735849, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789256, Length=451, Percent_Identity=25.0554323725055, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1790571, Length=453, Percent_Identity=23.841059602649, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17551876, Length=451, Percent_Identity=34.589800443459, Blast_Score=264, Evalue=6e-71,
Organism=Caenorhabditis elegans, GI71984122, Length=448, Percent_Identity=29.4642857142857, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17556372, Length=411, Percent_Identity=25.7907542579075, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI32566633, Length=283, Percent_Identity=27.9151943462898, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71994340, Length=336, Percent_Identity=23.8095238095238, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17535925, Length=337, Percent_Identity=24.3323442136499, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17535927, Length=337, Percent_Identity=24.3323442136499, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323011, Length=452, Percent_Identity=34.9557522123894, Blast_Score=272, Evalue=8e-74,
Organism=Saccharomyces cerevisiae, GI6321807, Length=450, Percent_Identity=28.4444444444444, Blast_Score=174, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6319872, Length=476, Percent_Identity=24.3697478991597, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6325153, Length=264, Percent_Identity=28.030303030303, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17136276, Length=458, Percent_Identity=33.4061135371179, Blast_Score=265, Evalue=4e-71,
Organism=Drosophila melanogaster, GI19921528, Length=438, Percent_Identity=30.1369863013699, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI19922416, Length=460, Percent_Identity=22.8260869565217, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24584738, Length=328, Percent_Identity=27.7439024390244, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24640851, Length=464, Percent_Identity=21.9827586206897, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24640849, Length=463, Percent_Identity=22.0302375809935, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020780
- InterPro:   IPR004523
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 49840; Mature: 49840

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRTLISELKNFINENVNLQGWIHKIRKLKNITFLIIRDRSGLIQCIVDNDKLDLSEVKI
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEEECCCCEEEEEECCCCCCHHHHHH
ESIVSMTGVVKESTNALNPFEIQVENLEIINAALDKVPIEINKENLEINLDTMLNNRILS
HHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHCCEEEECCCEEEEEEEHHCCCEEE
LRHPKVNSIFKVQNSIVNGFREFLNKEGFTEIYTPKIVWEGAEGGTEVFKVKYFENTAYL
ECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEEEECCCCCCEEEEEEEECCCCHH
AQSPQFYKQMMVVAGFERVFEIGHAYRAEEHNTNRHLNEYISMDLEIGFIKDEKDIMEVE
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEEEEEEEECCHHHHHHHH
ERLLKFILEKLNKECKEYFDLLDSELPKIESEIPKITFKEALDILIKEYNKNNLTCDLDP
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEHHHHHHHHHHHCCCCCEEEEECC
EGEKLICKYAKEKLDSDFIFLTNYPREKRPMYTMPLGKDGTHSFDLLFRGIEITTGGQRI
CCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCCCCCCCCHHHEEECEEEECCCCEE
HDYNMLVDNMEFKGLNPKDYESYLSAFKYGMPKHGGLAIGLERLTSRLLGLENVREAALI
EEHHHEEECCEECCCCCHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHCHHHHHHHHHH
TRDRTRLLP
CCCHHHCCC
>Mature Secondary Structure
MKRTLISELKNFINENVNLQGWIHKIRKLKNITFLIIRDRSGLIQCIVDNDKLDLSEVKI
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEEECCCCEEEEEECCCCCCHHHHHH
ESIVSMTGVVKESTNALNPFEIQVENLEIINAALDKVPIEINKENLEINLDTMLNNRILS
HHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHCCEEEECCCEEEEEEEHHCCCEEE
LRHPKVNSIFKVQNSIVNGFREFLNKEGFTEIYTPKIVWEGAEGGTEVFKVKYFENTAYL
ECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEEEECCCCCCEEEEEEEECCCCHH
AQSPQFYKQMMVVAGFERVFEIGHAYRAEEHNTNRHLNEYISMDLEIGFIKDEKDIMEVE
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEEEEEEEECCHHHHHHHH
ERLLKFILEKLNKECKEYFDLLDSELPKIESEIPKITFKEALDILIKEYNKNNLTCDLDP
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEHHHHHHHHHHHCCCCCEEEEECC
EGEKLICKYAKEKLDSDFIFLTNYPREKRPMYTMPLGKDGTHSFDLLFRGIEITTGGQRI
CCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCCCCCCCCHHHEEECEEEECCCCEE
HDYNMLVDNMEFKGLNPKDYESYLSAFKYGMPKHGGLAIGLERLTSRLLGLENVREAALI
EEHHHEEECCEECCCCCHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHCHHHHHHHHHH
TRDRTRLLP
CCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]