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The map label for this gene is alsR [H]

Identifier: 226948248

GI number: 226948248

Start: 1164794

End: 1165672

Strand: Reverse

Name: alsR [H]

Synonym: CLM_1126

Alternate gene names: 226948248

Gene position: 1165672-1164794 (Counterclockwise)

Preceding gene: 226948251

Following gene: 226948246

Centisome position: 28.05

GC content: 29.01

Gene sequence:

>879_bases
TTGAATTATGACTACTATAAAACCTTTATTGCTTTAGCCCAAACAAAAAATTTTTCAACAACAGCAAAAAAACTAAATAT
TTCTCAATCAACTGTGTCTAATAGAATTAAAGAGCTTGAAAAATATATTGGGTCTTCCCTTTTATATAGAACCAATAAAA
CTGTGGGATTAACTATAGCTGGGGAAGAATTTCTTCCCTACTGTAAAAGAATGATCCTGATTGAAGAGGAAGGAATGGCA
GTTCTAAACAATTTAAAGTATAAAGACTCAATAAAATTAGGCTCTGTACACTCCGCCTATGATGGTCATATTAAAAGGAC
TGTAAAGGATTTTTTAAAGAAACATGATGATGTATCCATAAAGATATTAATAAATCATAGTGATAAACTATTAGAATTTT
TAGTAGATGAAATTATAGACATCGCCATTGTATCTTATGTACCTACATCTAATAAGTACACAACCATACATACTTTGTGT
GATGACATTATTTTAGTTGCAAAAAATACATGTGACTTTAAGGATGAAATCTACGCTCATGAATTAAAAACCATGAAGTT
AATCTATGCAGATTGGAGTGATTCCTTTGAAGAATGGCTGAGACACCTAACTGGAGGACAAATGAATTATCAAATATATA
TTGATCAAGTCAATGAAGTCTTTGATTTTGTCCACGAAGGCTTTGGATATGCATTTGTTCTAAGTTCAATGGCTGAAAAG
TATTTTAAGATAGGTAGTCTTAAAAAAGTAATAATCAATAATGTAGCTCCTTATTTCTCTAAAAATTTCATTGTAATTAA
CAAGTATAAAGCTAATAATGCAAACATTAAAGCTTTCTTAAATGTTTCATATGATACAGATTTATCAGATAAAATCTAA

Upstream 100 bases:

>100_bases
AGTAATTATATCTTTATAATATAATATATGGTATCATTTGTATAACGAATAATATAGTTTATAACAATCGATGATACGAA
TAATAAACGAGGTGTTTTCT

Downstream 100 bases:

>100_bases
ACGGTTTAATTGTATCTAAGGTTAATAACGTATTATAATAGACGCAATCTAAGAAATATAGTTATACTACTATTAAATTT
CTTAGATTGTGTAAAAGTAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MNYDYYKTFIALAQTKNFSTTAKKLNISQSTVSNRIKELEKYIGSSLLYRTNKTVGLTIAGEEFLPYCKRMILIEEEGMA
VLNNLKYKDSIKLGSVHSAYDGHIKRTVKDFLKKHDDVSIKILINHSDKLLEFLVDEIIDIAIVSYVPTSNKYTTIHTLC
DDIILVAKNTCDFKDEIYAHELKTMKLIYADWSDSFEEWLRHLTGGQMNYQIYIDQVNEVFDFVHEGFGYAFVLSSMAEK
YFKIGSLKKVIINNVAPYFSKNFIVINKYKANNANIKAFLNVSYDTDLSDKI

Sequences:

>Translated_292_residues
MNYDYYKTFIALAQTKNFSTTAKKLNISQSTVSNRIKELEKYIGSSLLYRTNKTVGLTIAGEEFLPYCKRMILIEEEGMA
VLNNLKYKDSIKLGSVHSAYDGHIKRTVKDFLKKHDDVSIKILINHSDKLLEFLVDEIIDIAIVSYVPTSNKYTTIHTLC
DDIILVAKNTCDFKDEIYAHELKTMKLIYADWSDSFEEWLRHLTGGQMNYQIYIDQVNEVFDFVHEGFGYAFVLSSMAEK
YFKIGSLKKVIINNVAPYFSKNFIVINKYKANNANIKAFLNVSYDTDLSDKI
>Mature_292_residues
MNYDYYKTFIALAQTKNFSTTAKKLNISQSTVSNRIKELEKYIGSSLLYRTNKTVGLTIAGEEFLPYCKRMILIEEEGMA
VLNNLKYKDSIKLGSVHSAYDGHIKRTVKDFLKKHDDVSIKILINHSDKLLEFLVDEIIDIAIVSYVPTSNKYTTIHTLC
DDIILVAKNTCDFKDEIYAHELKTMKLIYADWSDSFEEWLRHLTGGQMNYQIYIDQVNEVFDFVHEGFGYAFVLSSMAEK
YFKIGSLKKVIINNVAPYFSKNFIVINKYKANNANIKAFLNVSYDTDLSDKI

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790208, Length=218, Percent_Identity=26.605504587156, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787879, Length=157, Percent_Identity=26.7515923566879, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367136, Length=248, Percent_Identity=24.1935483870968, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI48994962, Length=158, Percent_Identity=22.7848101265823, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33662; Mature: 33662

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYDYYKTFIALAQTKNFSTTAKKLNISQSTVSNRIKELEKYIGSSLLYRTNKTVGLTIA
CCCHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCHHEEECCCEEEEEEE
GEEFLPYCKRMILIEEEGMAVLNNLKYKDSIKLGSVHSAYDGHIKRTVKDFLKKHDDVSI
CHHHHHHHHHEEEECCCCHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCEE
KILINHSDKLLEFLVDEIIDIAIVSYVPTSNKYTTIHTLCDDIILVAKNTCDFKDEIYAH
EEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHEEEECCCCCCHHHHHHH
ELKTMKLIYADWSDSFEEWLRHLTGGQMNYQIYIDQVNEVFDFVHEGFGYAFVLSSMAEK
HHHEEEEEEECCCHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHCCHHHHHHHHHHHH
YFKIGSLKKVIINNVAPYFSKNFIVINKYKANNANIKAFLNVSYDTDLSDKI
HHHHCCHHHHHHHHCCHHHCCCEEEEEEEECCCCCEEEEEEEEECCCCCCCC
>Mature Secondary Structure
MNYDYYKTFIALAQTKNFSTTAKKLNISQSTVSNRIKELEKYIGSSLLYRTNKTVGLTIA
CCCHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCHHEEECCCEEEEEEE
GEEFLPYCKRMILIEEEGMAVLNNLKYKDSIKLGSVHSAYDGHIKRTVKDFLKKHDDVSI
CHHHHHHHHHEEEECCCCHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCEE
KILINHSDKLLEFLVDEIIDIAIVSYVPTSNKYTTIHTLCDDIILVAKNTCDFKDEIYAH
EEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHEEEECCCCCCHHHHHHH
ELKTMKLIYADWSDSFEEWLRHLTGGQMNYQIYIDQVNEVFDFVHEGFGYAFVLSSMAEK
HHHEEEEEEECCCHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHCCHHHHHHHHHHHH
YFKIGSLKKVIINNVAPYFSKNFIVINKYKANNANIKAFLNVSYDTDLSDKI
HHHHCCHHHHHHHHCCHHHCCCEEEEEEEECCCCCEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]