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The map label for this gene is yvrH [H]

Identifier: 226948239

GI number: 226948239

Start: 1156460

End: 1157182

Strand: Direct

Name: yvrH [H]

Synonym: CLM_1116

Alternate gene names: 226948239

Gene position: 1156460-1157182 (Clockwise)

Preceding gene: 226948238

Following gene: 226948240

Centisome position: 27.83

GC content: 27.11

Gene sequence:

>723_bases
ATGGAGACAATATCTTTAAGTAATAAAAAAATATTAATAATTGATGATGAGGAAGATATAGTTAGATTAATAAGAACGGT
ACTTAAAAAAGAAGGATTTCAAAATATATATTATGCTACTAACTTAGAAGATGGATTTAAAGAATTTAATAAGGTAGAGC
CAGATATTGTAATTTTAGATATTATGTTACCAGATGGAGAAGGATATGAATTATGTAAGACAATAAGAGCTAAATCTAAG
GTACCCATACTATTTTTATCTGCTAAGGGTGAAGAAATAGATAAAATATTAGGATTTGCTATAGGTGGAGATGATTATAT
AACTAAACCCTTTAGTACAAAGGAGTTAGCCTATAGGGTAAAGGCTCATTTAAGAAGGTATTCCTACGTGGAAAATGCTA
GCGAGGAAAAAAATATTTTATCCTTTGGACCATTTGAGTTAAATATAAGTAAGGGAGAATTTAAAAAAGAAGGAAGGCTT
ATAGAATTAAAACCTAAAGAATTAGCATTAATAGCTTTTTTTGCAAAACATCCAAATCAAATAATAAGTAAAGAAAAAAT
TTGTGATAATGTTTGGGGAGAAGATTATTATGGATTCGATAATACTATAATGGTTCATATTAGAAGACTTAGAGAAAAAA
TTGAAAAAGAACCATCAAAGCCAGAGTATTTAATAAATGTTAAAGGTTTAGGGTACAAATTGGTGATAAAAAATGAAAAA
TAA

Upstream 100 bases:

>100_bases
GTTTAAAATTTTGTTATACTAAAAATAAATTTGTTATAATAAATTTAAACTCAATGAAAATTTAAATTTACATAAAATTA
AAAGAAAAAGAGGGAATAAT

Downstream 100 bases:

>100_bases
TATGAAATGGAGAATAACAGGTAGGTTTTTAATAACAGTTATATGTGTAGTTATAACTGTAGTCATAATAAATATTGTAT
CTTTAATTGGACTCGCAATT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
METISLSNKKILIIDDEEDIVRLIRTVLKKEGFQNIYYATNLEDGFKEFNKVEPDIVILDIMLPDGEGYELCKTIRAKSK
VPILFLSAKGEEIDKILGFAIGGDDYITKPFSTKELAYRVKAHLRRYSYVENASEEKNILSFGPFELNISKGEFKKEGRL
IELKPKELALIAFFAKHPNQIISKEKICDNVWGEDYYGFDNTIMVHIRRLREKIEKEPSKPEYLINVKGLGYKLVIKNEK

Sequences:

>Translated_240_residues
METISLSNKKILIIDDEEDIVRLIRTVLKKEGFQNIYYATNLEDGFKEFNKVEPDIVILDIMLPDGEGYELCKTIRAKSK
VPILFLSAKGEEIDKILGFAIGGDDYITKPFSTKELAYRVKAHLRRYSYVENASEEKNILSFGPFELNISKGEFKKEGRL
IELKPKELALIAFFAKHPNQIISKEKICDNVWGEDYYGFDNTIMVHIRRLREKIEKEPSKPEYLINVKGLGYKLVIKNEK
>Mature_240_residues
METISLSNKKILIIDDEEDIVRLIRTVLKKEGFQNIYYATNLEDGFKEFNKVEPDIVILDIMLPDGEGYELCKTIRAKSK
VPILFLSAKGEEIDKILGFAIGGDDYITKPFSTKELAYRVKAHLRRYSYVENASEEKNILSFGPFELNISKGEFKKEGRL
IELKPKELALIAFFAKHPNQIISKEKICDNVWGEDYYGFDNTIMVHIRRLREKIEKEPSKPEYLINVKGLGYKLVIKNEK

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=35.1694915254237, Blast_Score=161, Evalue=3e-41,
Organism=Escherichia coli, GI1786599, Length=235, Percent_Identity=37.0212765957447, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=30.9734513274336, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=32.1888412017167, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=31.8777292576419, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=31.0043668122271, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=30.7692307692308, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=31.858407079646, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=30.5309734513274, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=30.2631578947368, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=30.7359307359307, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=30.0884955752212, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=27.2321428571429, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=25.764192139738, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1788550, Length=157, Percent_Identity=26.7515923566879, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788191, Length=113, Percent_Identity=35.3982300884956, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27760; Mature: 27760

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METISLSNKKILIIDDEEDIVRLIRTVLKKEGFQNIYYATNLEDGFKEFNKVEPDIVILD
CCCEECCCCEEEEEECHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCCEEEEE
IMLPDGEGYELCKTIRAKSKVPILFLSAKGEEIDKILGFAIGGDDYITKPFSTKELAYRV
EEECCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHEEECCCCCCCCCCCHHHHHHHH
KAHLRRYSYVENASEEKNILSFGPFELNISKGEFKKEGRLIELKPKELALIAFFAKHPNQ
HHHHHHHHHHHCCCCCCCCEEECCEEEEECCCCHHHCCCEEEECCCCEEEEEEEHHCCHH
IISKEKICDNVWGEDYYGFDNTIMVHIRRLREKIEKEPSKPEYLINVKGLGYKLVIKNEK
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEECCC
>Mature Secondary Structure
METISLSNKKILIIDDEEDIVRLIRTVLKKEGFQNIYYATNLEDGFKEFNKVEPDIVILD
CCCEECCCCEEEEEECHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCCEEEEE
IMLPDGEGYELCKTIRAKSKVPILFLSAKGEEIDKILGFAIGGDDYITKPFSTKELAYRV
EEECCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHEEECCCCCCCCCCCHHHHHHHH
KAHLRRYSYVENASEEKNILSFGPFELNISKGEFKKEGRLIELKPKELALIAFFAKHPNQ
HHHHHHHHHHHCCCCCCCCEEECCEEEEECCCCHHHCCCEEEECCCCEEEEEEEHHCCHH
IISKEKICDNVWGEDYYGFDNTIMVHIRRLREKIEKEPSKPEYLINVKGLGYKLVIKNEK
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]