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The map label for this gene is arsR [H]

Identifier: 226948044

GI number: 226948044

Start: 965230

End: 965553

Strand: Direct

Name: arsR [H]

Synonym: CLM_0905

Alternate gene names: 226948044

Gene position: 965230-965553 (Clockwise)

Preceding gene: 226948042

Following gene: 226948045

Centisome position: 23.23

GC content: 26.85

Gene sequence:

>324_bases
ATGAGCTTAAATTATGATGATAATGCAAAAATTATTAAAGCATTATCAGATGGTAGTAGATTAAAAATAATTGATATATT
GTCTTGTGGAGAAAAGTGTGCTTGTGATATATTGGAGCACTTTGGTTTTACACAACCAACACTTTCTCATCATATGAAGG
TTTTAATTGATTGTGGATTGGTGAAGTCTAGAAAAGAGGGATTATGGAGTTACTATTCATTGAATATTACTAATTGTAAT
AAATTAATTTTATTTTTCATGAATATTATAACGGATACAGACGACTGTATCTGTAAGAATAAATCAAAATGTGATTGTAA
ATAA

Upstream 100 bases:

>100_bases
TAAAGGTGTATCATGTACTGATAAATACAAAATATATTGACATTAAATAGAATAAGTTCTATACTGTATATAGATGAATA
TCTATATAGGAGGGGAATTT

Downstream 100 bases:

>100_bases
AAAAAGAGGAGTGAATTATTATGAAAAAAATGATAATTTTTGATCCAGCTATGTGTTGTTCAACAGGAGTGTGCGGTCCA
TCTGTTGATCCAGAATTATT

Product: putative arsenical resistance operon repressor ArsR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 107; Mature: 106

Protein sequence:

>107_residues
MSLNYDDNAKIIKALSDGSRLKIIDILSCGEKCACDILEHFGFTQPTLSHHMKVLIDCGLVKSRKEGLWSYYSLNITNCN
KLILFFMNIITDTDDCICKNKSKCDCK

Sequences:

>Translated_107_residues
MSLNYDDNAKIIKALSDGSRLKIIDILSCGEKCACDILEHFGFTQPTLSHHMKVLIDCGLVKSRKEGLWSYYSLNITNCN
KLILFFMNIITDTDDCICKNKSKCDCK
>Mature_106_residues
SLNYDDNAKIIKALSDGSRLKIIDILSCGEKCACDILEHFGFTQPTLSHHMKVLIDCGLVKSRKEGLWSYYSLNITNCNK
LILFFMNIITDTDDCICKNKSKCDCK

Specific function: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenat

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12130; Mature: 11999

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS00846 HTH_ARSR_1 ; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

8.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
11.2 %Cys+Met (Translated Protein)
8.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
10.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNYDDNAKIIKALSDGSRLKIIDILSCGEKCACDILEHFGFTQPTLSHHMKVLIDCGL
CCCCCCCCHHEEEECCCCCEEEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
VKSRKEGLWSYYSLNITNCNKLILFFMNIITDTDDCICKNKSKCDCK
HHCHHCCCEEEEEEEECCHHHHHHHHHHHHCCCCHHHCCCCCCCCCC
>Mature Secondary Structure 
SLNYDDNAKIIKALSDGSRLKIIDILSCGEKCACDILEHFGFTQPTLSHHMKVLIDCGL
CCCCCCCHHEEEECCCCCEEEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
VKSRKEGLWSYYSLNITNCNKLILFFMNIITDTDDCICKNKSKCDCK
HHCHHCCCEEEEEEEECCHHHHHHHHHHHHCCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1534328 [H]