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The map label for this gene is soxS [H]

Identifier: 226947981

GI number: 226947981

Start: 902232

End: 903197

Strand: Direct

Name: soxS [H]

Synonym: CLM_0842

Alternate gene names: 226947981

Gene position: 902232-903197 (Clockwise)

Preceding gene: 226947980

Following gene: 226947982

Centisome position: 21.71

GC content: 38.1

Gene sequence:

>966_bases
ATGTACGAGTGGCAGAAGCAAATTCAAATAATCGTTGATGAAATTGACAAATGTATTAAAAATTATAATGATGAAGCCTT
GACACTACGCTTTCTTTCTCGCAGGCTGGGTTATTCCGAATTTTATACAACGAGAAAATTCAAAGAAATATCGGGTATGC
AATTTAGGGATTATCTGCGGCATAGAAAATTAGCCTTTGCATTAAAAGAGGTTCGGGATAGTGAAAAAAGTATTTTGGAT
ATTGCCTTTGATTATGGTTTTTCATCACATGAAGCTTTTACCAGAGCTTTCAAGAGAACATATGGTGTAACTCCAAGTGA
ATACCGAAAAAAGCCTAATCCTGTCGTTCTTCGTACAAAAATAAACCCTTTCGACCGCTACTTTTTAGGATTGGGAGAGA
TTGGTATGATGAAATCTACAGATAATGTTAAAATTTATTTTGTAACCATTCCCGCACACAAATTTTTGCACATTAAAAAC
TATGAGAGTAATGGGTATTGGGATTTTTGGCAAAAGCAAAGTCTTATTCCGGGACAGGACTGCGAAACAATTTGCGGCTT
ACTCGATAGTATCAAGGGCAAATTGGATGATGATGGTGGGAGCGAATCTAACAGCGGCAGCGGTCAGATTATGGCGTACA
TTAATGACCCGGACGGCAGACTCTGCGATTGGGGTATTCCACGTACAGAGTGTTATGGTGTACGTCTTCCTTTTGATTAT
AAAGGCGAAGTACCACCACAAATGCTTATGATTGATGTTCCCGAGGCCGAATATATTGTTTTTGAACATGGGCCATTCGA
TTATGAGCAGGAAAATCGTAGTGTGGAGGAAAAGATTGAAAAGGCAATGGCAACTTTTGATTTTGCAGGCACTGGTTACT
GTTTTGATACTTCTCCCGGTAGAATAATTTACTTTTATTTTAATCCGGAACAGTTTTTTAAGTATATTAGACCAGTGCGG
AAGTAA

Upstream 100 bases:

>100_bases
TTAAAAGAGAAAAATGAAATAACAGCAAGTAAAATCAAGCAGTAATCTTTCTATTTCTTTATAATAAATGTAGGACGGTT
GAAACGAGGTGAACAGACGA

Downstream 100 bases:

>100_bases
ATAAAATCGACTGCCTATCCACTATTGTTTCTAACGAGAAAACCAAACAGGAAATGACAAATTCCAATTTGTATTCAGAG
CTACTGAAATTTGTTGCTAT

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MYEWQKQIQIIVDEIDKCIKNYNDEALTLRFLSRRLGYSEFYTTRKFKEISGMQFRDYLRHRKLAFALKEVRDSEKSILD
IAFDYGFSSHEAFTRAFKRTYGVTPSEYRKKPNPVVLRTKINPFDRYFLGLGEIGMMKSTDNVKIYFVTIPAHKFLHIKN
YESNGYWDFWQKQSLIPGQDCETICGLLDSIKGKLDDDGGSESNSGSGQIMAYINDPDGRLCDWGIPRTECYGVRLPFDY
KGEVPPQMLMIDVPEAEYIVFEHGPFDYEQENRSVEEKIEKAMATFDFAGTGYCFDTSPGRIIYFYFNPEQFFKYIRPVR
K

Sequences:

>Translated_321_residues
MYEWQKQIQIIVDEIDKCIKNYNDEALTLRFLSRRLGYSEFYTTRKFKEISGMQFRDYLRHRKLAFALKEVRDSEKSILD
IAFDYGFSSHEAFTRAFKRTYGVTPSEYRKKPNPVVLRTKINPFDRYFLGLGEIGMMKSTDNVKIYFVTIPAHKFLHIKN
YESNGYWDFWQKQSLIPGQDCETICGLLDSIKGKLDDDGGSESNSGSGQIMAYINDPDGRLCDWGIPRTECYGVRLPFDY
KGEVPPQMLMIDVPEAEYIVFEHGPFDYEQENRSVEEKIEKAMATFDFAGTGYCFDTSPGRIIYFYFNPEQFFKYIRPVR
K
>Mature_321_residues
MYEWQKQIQIIVDEIDKCIKNYNDEALTLRFLSRRLGYSEFYTTRKFKEISGMQFRDYLRHRKLAFALKEVRDSEKSILD
IAFDYGFSSHEAFTRAFKRTYGVTPSEYRKKPNPVVLRTKINPFDRYFLGLGEIGMMKSTDNVKIYFVTIPAHKFLHIKN
YESNGYWDFWQKQSLIPGQDCETICGLLDSIKGKLDDDGGSESNSGSGQIMAYINDPDGRLCDWGIPRTECYGVRLPFDY
KGEVPPQMLMIDVPEAEYIVFEHGPFDYEQENRSVEEKIEKAMATFDFAGTGYCFDTSPGRIIYFYFNPEQFFKYIRPVR
K

Specific function: Transcriptional activator of the superoxide response regulon of E.coli that includes at least 10 genes such as sodA, nfo, zwf and micF. Binds the DNA sequence 5'-GCACN(7)CAA-3'. It also facilitates the subsequent binding of RNA polymerase to the micF and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790497, Length=107, Percent_Identity=37.3831775700935, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1790857, Length=102, Percent_Identity=34.3137254901961, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081928, Length=100, Percent_Identity=34, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 2500 (L-broth) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37656; Mature: 37656

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYEWQKQIQIIVDEIDKCIKNYNDEALTLRFLSRRLGYSEFYTTRKFKEISGMQFRDYLR
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHH
HRKLAFALKEVRDSEKSILDIAFDYGFSSHEAFTRAFKRTYGVTPSEYRKKPNPVVLRTK
HHHHHHHHHHHHCCHHHEEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEE
INPFDRYFLGLGEIGMMKSTDNVKIYFVTIPAHKFLHIKNYESNGYWDFWQKQSLIPGQD
CCHHHHHHHCCCCCCCEECCCCEEEEEEEECCEEEEEEEECCCCCCCCHHHCCCCCCCCC
CETICGLLDSIKGKLDDDGGSESNSGSGQIMAYINDPDGRLCDWGIPRTECYGVRLPFDY
HHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCCCCCCCEEEEECCCCC
KGEVPPQMLMIDVPEAEYIVFEHGPFDYEQENRSVEEKIEKAMATFDFAGTGYCFDTSPG
CCCCCCEEEEEECCCCCEEEEECCCCCCHHHCCHHHHHHHHHHHHHCCCCCCEEEECCCC
RIIYFYFNPEQFFKYIRPVRK
EEEEEEECHHHHHHHHHHHCC
>Mature Secondary Structure
MYEWQKQIQIIVDEIDKCIKNYNDEALTLRFLSRRLGYSEFYTTRKFKEISGMQFRDYLR
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHH
HRKLAFALKEVRDSEKSILDIAFDYGFSSHEAFTRAFKRTYGVTPSEYRKKPNPVVLRTK
HHHHHHHHHHHHCCHHHEEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEE
INPFDRYFLGLGEIGMMKSTDNVKIYFVTIPAHKFLHIKNYESNGYWDFWQKQSLIPGQD
CCHHHHHHHCCCCCCCEECCCCEEEEEEEECCEEEEEEEECCCCCCCCHHHCCCCCCCCC
CETICGLLDSIKGKLDDDGGSESNSGSGQIMAYINDPDGRLCDWGIPRTECYGVRLPFDY
HHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCCCCCCCEEEEECCCCC
KGEVPPQMLMIDVPEAEYIVFEHGPFDYEQENRSVEEKIEKAMATFDFAGTGYCFDTSPG
CCCCCCEEEEEECCCCCEEEEECCCCCCHHHCCHHHHHHHHHHHHHCCCCCCEEEECCCC
RIIYFYFNPEQFFKYIRPVRK
EEEEEEECHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]