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The map label for this gene is msmR [H]

Identifier: 226947944

GI number: 226947944

Start: 864041

End: 864862

Strand: Direct

Name: msmR [H]

Synonym: CLM_0802

Alternate gene names: 226947944

Gene position: 864041-864862 (Clockwise)

Preceding gene: 226947942

Following gene: 226947945

Centisome position: 20.79

GC content: 36.74

Gene sequence:

>822_bases
ATGGAAATCAACTTAATAGATCTTGTAGAACATTTTGCTCATACTGCTTTTCAAGTAGAAGGAGTATATAATTATAGTAT
TGAACCGGGGAGTGCGGGCATTATGAAAACTTCTCCATTTCCAGGATTTATCTTTCCCTTAGCAGGTGAGGCGAATTTCA
TTTTTGATGGTACTTCTTACACAGCAGGCCTTGGAAATGTGATTCATGGTGGCGCTAATATGAGGTTGAGTAAGAAGGTA
ATTGGTAAAAAAAAATGGAATTATATTTTGGTTCTTTACAGTATTCGTAAGCCTGAACCAGAAGGATTTTCCCTAGAAGA
TTCACATTTTGAACTTGTTCTAGGACAAAGTCCTAGACTCGTTGATTTGCTACAACGATTATGGAGAGTATCAAATCAAC
CTGGAGCAATCGCTACATTCCAAAAGGAAACCATATTTCGTTGCATATTGGATGAAGTTTTTATATGTGCACGTAACCAG
TCAAGTGGTGATGATCGTATATTGTTTAAACAAGTATCTGACTACATTCACGAATACTATATGGACACACTTACTATTCG
ATCCCTTGCCGAACTACATGGGGTAAATGAGAATAGATTGTTCTATGTATTCTCAAAATATGCAGGAATGGGAGCAGGAG
ATTATCTTATGATTCATAGGCTAAATCGTGCAAAGGAATTGTTGGTAACAGGTAATGCTCCTGTAGTGGCGGTAGCGAAA
AGTGTGGGTTATCATGATCCATATCATTTTAGTAAGAGATTCAAAAAGCAATTTGGTATTTCTCCAAGTAAATTTCGGGA
CAAGTTCAGATATAAAGGATGA

Upstream 100 bases:

>100_bases
TCAATCATTAAGATTTTTTCATAAATGATTGAGCTATTTTTTTGAGAATAATATTATGGGAAATTGCTATAAAACTTAGT
AAAAAAGGGGGGAGTATTAA

Downstream 100 bases:

>100_bases
TGCTTTTAATCTGTTTGCCATTTTAGTAGAATTAAATCATGTTATACTACTTGCTTTTTATATTTAAATAGATAAAAGAA
AGTTTTTAGATTCTTATTTT

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MEINLIDLVEHFAHTAFQVEGVYNYSIEPGSAGIMKTSPFPGFIFPLAGEANFIFDGTSYTAGLGNVIHGGANMRLSKKV
IGKKKWNYILVLYSIRKPEPEGFSLEDSHFELVLGQSPRLVDLLQRLWRVSNQPGAIATFQKETIFRCILDEVFICARNQ
SSGDDRILFKQVSDYIHEYYMDTLTIRSLAELHGVNENRLFYVFSKYAGMGAGDYLMIHRLNRAKELLVTGNAPVVAVAK
SVGYHDPYHFSKRFKKQFGISPSKFRDKFRYKG

Sequences:

>Translated_273_residues
MEINLIDLVEHFAHTAFQVEGVYNYSIEPGSAGIMKTSPFPGFIFPLAGEANFIFDGTSYTAGLGNVIHGGANMRLSKKV
IGKKKWNYILVLYSIRKPEPEGFSLEDSHFELVLGQSPRLVDLLQRLWRVSNQPGAIATFQKETIFRCILDEVFICARNQ
SSGDDRILFKQVSDYIHEYYMDTLTIRSLAELHGVNENRLFYVFSKYAGMGAGDYLMIHRLNRAKELLVTGNAPVVAVAK
SVGYHDPYHFSKRFKKQFGISPSKFRDKFRYKG
>Mature_273_residues
MEINLIDLVEHFAHTAFQVEGVYNYSIEPGSAGIMKTSPFPGFIFPLAGEANFIFDGTSYTAGLGNVIHGGANMRLSKKV
IGKKKWNYILVLYSIRKPEPEGFSLEDSHFELVLGQSPRLVDLLQRLWRVSNQPGAIATFQKETIFRCILDEVFICARNQ
SSGDDRILFKQVSDYIHEYYMDTLTIRSLAELHGVNENRLFYVFSKYAGMGAGDYLMIHRLNRAKELLVTGNAPVVAVAK
SVGYHDPYHFSKRFKKQFGISPSKFRDKFRYKG

Specific function: Regulatory protein for the msm operon for multiple sugar metabolism. Activates the transcription of the msmEFGK, aga, dexB and gftA genes [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790391, Length=110, Percent_Identity=33.6363636363636, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF02311 AraC_binding; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 31012; Mature: 31012

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEINLIDLVEHFAHTAFQVEGVYNYSIEPGSAGIMKTSPFPGFIFPLAGEANFIFDGTSY
CCCHHHHHHHHHHHHEEEEEEEEEEEECCCCCCCEECCCCCCEEEEECCCCEEEECCCCC
TAGLGNVIHGGANMRLSKKVIGKKKWNYILVLYSIRKPEPEGFSLEDSHFELVLGQSPRL
CCCCCHHEECCCCCEEHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCH
VDLLQRLWRVSNQPGAIATFQKETIFRCILDEVFICARNQSSGDDRILFKQVSDYIHEYY
HHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHH
MDTLTIRSLAELHGVNENRLFYVFSKYAGMGAGDYLMIHRLNRAKELLVTGNAPVVAVAK
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCEEEEEH
SVGYHDPYHFSKRFKKQFGISPSKFRDKFRYKG
HCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCC
>Mature Secondary Structure
MEINLIDLVEHFAHTAFQVEGVYNYSIEPGSAGIMKTSPFPGFIFPLAGEANFIFDGTSY
CCCHHHHHHHHHHHHEEEEEEEEEEEECCCCCCCEECCCCCCEEEEECCCCEEEECCCCC
TAGLGNVIHGGANMRLSKKVIGKKKWNYILVLYSIRKPEPEGFSLEDSHFELVLGQSPRL
CCCCCHHEECCCCCEEHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCH
VDLLQRLWRVSNQPGAIATFQKETIFRCILDEVFICARNQSSGDDRILFKQVSDYIHEYY
HHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHH
MDTLTIRSLAELHGVNENRLFYVFSKYAGMGAGDYLMIHRLNRAKELLVTGNAPVVAVAK
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCEEEEEH
SVGYHDPYHFSKRFKKQFGISPSKFRDKFRYKG
HCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1537846; 12397186 [H]