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The map label for this gene is cat [H]

Identifier: 226947872

GI number: 226947872

Start: 783848

End: 784474

Strand: Reverse

Name: cat [H]

Synonym: CLM_0727

Alternate gene names: 226947872

Gene position: 784474-783848 (Counterclockwise)

Preceding gene: 226947875

Following gene: 226947869

Centisome position: 18.88

GC content: 23.76

Gene sequence:

>627_bases
ATGAAGTATATTGATTTTAATGATTTTGAAAGAATAGAGCATTATAAATTTTTTGAAAATGTTGATAATCCACAATTTAA
TATATGCATGAATATTGATGTAACAAATTTTTTGAGATTTGTAAAAAGCAATAAAATATCATTCTATTATAGTATGATCT
ACGCTTCTACACATGTGATGAATGAAATAGAAGATTTTCGTTATAAAATTAGAGATGGAAAAATCATTCTGCATGACTCT
TTACAACCATCATTTACAGATATAGAATCCAATAAAAATTTATTTAAAATTGTTACCTTGCCTCTTAAAAAGGATATTAT
AGAATTTTCAAATTATGCAAGAGAAACTTCAATAAATCAAAAAGAATATTTTCCAAAAATAGCTGAGAATCAAGATAAAC
TAATATACTTTTCTTGTATACCTTGGATATCCTTTACTAGTATTTCAAATGAAATTGTAATGAATAAAGAAGATTCTATA
CCTAGAATCTCCTTTGGAAAGTATTTTAAACAAGGCAATAAAGTTTTATTACCATATTCTGTACAAGTAAACCACATGCT
ATTAGATGGTATCCATGTTGGTAAGTATATTGAAAAATTACAAAACTTTATTAATAAGTTTAAATAA

Upstream 100 bases:

>100_bases
ATTTAATATATCGTTATTTTTATTACTTGTCAAATAAAAATAACTATTTTTTATCAAATAGTATTAAACTAAAATAATAA
ATTTATATTTAGGAGGAATT

Downstream 100 bases:

>100_bases
TACTTTAACTTTAGATATAATGCTACCCTTCTAAAAAATCATCCAGAAAGATATTTTATTGTTTACCTCTTCACTGTTAA
TACAGAAACAATACGTGCTT

Product: chloramphenicol acetyltransferase family protein

Products: NA

Alternate protein names: CAT [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKYIDFNDFERIEHYKFFENVDNPQFNICMNIDVTNFLRFVKSNKISFYYSMIYASTHVMNEIEDFRYKIRDGKIILHDS
LQPSFTDIESNKNLFKIVTLPLKKDIIEFSNYARETSINQKEYFPKIAENQDKLIYFSCIPWISFTSISNEIVMNKEDSI
PRISFGKYFKQGNKVLLPYSVQVNHMLLDGIHVGKYIEKLQNFINKFK

Sequences:

>Translated_208_residues
MKYIDFNDFERIEHYKFFENVDNPQFNICMNIDVTNFLRFVKSNKISFYYSMIYASTHVMNEIEDFRYKIRDGKIILHDS
LQPSFTDIESNKNLFKIVTLPLKKDIIEFSNYARETSINQKEYFPKIAENQDKLIYFSCIPWISFTSISNEIVMNKEDSI
PRISFGKYFKQGNKVLLPYSVQVNHMLLDGIHVGKYIEKLQNFINKFK
>Mature_208_residues
MKYIDFNDFERIEHYKFFENVDNPQFNICMNIDVTNFLRFVKSNKISFYYSMIYASTHVMNEIEDFRYKIRDGKIILHDS
LQPSFTDIESNKNLFKIVTLPLKKDIIEFSNYARETSINQKEYFPKIAENQDKLIYFSCIPWISFTSISNEIVMNKEDSI
PRISFGKYFKQGNKVLLPYSVQVNHMLLDGIHVGKYIEKLQNFINKFK

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG4845

COG function: function code V; Chloramphenicol O-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloramphenicol acetyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023213
- InterPro:   IPR018372
- InterPro:   IPR001707
- ProDom:   PD002660 [H]

Pfam domain/function: PF00302 CAT [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 24861; Mature: 24861

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYIDFNDFERIEHYKFFENVDNPQFNICMNIDVTNFLRFVKSNKISFYYSMIYASTHVM
CCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHCCCCEEEHHHHHHHHHHH
NEIEDFRYKIRDGKIILHDSLQPSFTDIESNKNLFKIVTLPLKKDIIEFSNYARETSINQ
HHHHHHHEEECCCEEEEECCCCCCCCHHCCCCCEEEEEEECHHHHHHHHHHHHHHCCCCH
KEYFPKIAENQDKLIYFSCIPWISFTSISNEIVMNKEDSIPRISFGKYFKQGNKVLLPYS
HHHCCHHHCCCCCEEEEEECCCEEEECCCCEEEECCCCCCCCCHHHHHHHCCCEEEEEEE
VQVNHMLLDGIHVGKYIEKLQNFINKFK
EEECEEEECCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKYIDFNDFERIEHYKFFENVDNPQFNICMNIDVTNFLRFVKSNKISFYYSMIYASTHVM
CCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHCCCCEEEHHHHHHHHHHH
NEIEDFRYKIRDGKIILHDSLQPSFTDIESNKNLFKIVTLPLKKDIIEFSNYARETSINQ
HHHHHHHEEECCCEEEEECCCCCCCCHHCCCCCEEEEEEECHHHHHHHHHHHHHHCCCCH
KEYFPKIAENQDKLIYFSCIPWISFTSISNEIVMNKEDSIPRISFGKYFKQGNKVLLPYS
HHHCCHHHCCCCCEEEEEECCCEEEECCCCEEEECCCCCCCCCHHHHHHHCCCEEEEEEE
VQVNHMLLDGIHVGKYIEKLQNFINKFK
EEECEEEECCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1650008 [H]