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The map label for this gene is rodA [H]

Identifier: 226947868

GI number: 226947868

Start: 777626

End: 778786

Strand: Direct

Name: rodA [H]

Synonym: CLM_0723

Alternate gene names: 226947868

Gene position: 777626-778786 (Clockwise)

Preceding gene: 226947864

Following gene: 226947870

Centisome position: 18.71

GC content: 29.03

Gene sequence:

>1161_bases
TTGATTAGAAGAAAGAATGCTAATTTAAATAAATCTTTTAATTTAAAAAGGCACATAAAATATTTTGATATTTTTTTGTT
TGCTGTTGTAATTCTTATATCAATTTTAGGGATTGTTATGATTAGTAGTGCAACATCTAATTTTGAAAATAGCAAAAAAT
ACATTATTACTCAAATTTTATCCCTTGCAATTGGATTGGTTTTCATGTTTATAACAATTTATATAGATTACCGAAATATT
GGACGGGCCTATAAGATTATTTATATATTTAATTTTCTATTACTGGCAGGTGTAATTCTTCTTGGTACTGGTAAAGACCA
ATGGGGAGCACAAAGGTGGATACGAATAGGGGGGATAGGAATACAACCATCAGAAATTGCAAAAATAGGATTTATTATAA
CTTTTGCAAAATTTTTGGAATTAATAAAAGACGATTTAAATAAAATAAAATATTTATTGGCGGCCTTTTGTTATATTGGA
GTGCCTATTATACTTGTAATGATCCAACCGGATTTAGGAACTGCTCTATCCTTTGTTTTTATTTCTATTGCAATGCTATA
TATTTGTGGTATAGATTATAAATATATTTTAGGGGGATTTTTAGCCTGCATTGTTATTATACCTATTGCTTGGCAATATG
TGCTTAAAGCATATCAAAAGAATAGAATTTTAATTTTTATTAATCCTGATTCAGATCCTATGGGAGGAGGATACCATGTT
CTTCAGTCTAAAATAGCAGTAGGTTCTGGCGAATTTTTTGGTACAGGATTATTTAAGGGTTCTCATGCACAAAATTTTCT
GCCTGAAAAGCATACAGACTTTATATTTGCTCTTATTGGGGAAGAATTGGGCTTTATAGGAAGTATAATTGTGGTATTAC
TTCTTTTAATAATAGTCTTAAGATGTATTTCAATAGCCAAATCTGCTAAAGACAATTTGGGATGTTATATTTGTGTTGGA
GTTGCCAGTATGATCATATTCCAGACTTTTATAAATATTGGAATGTGTATTGGTATTATGCCTGTTACAGGTATTCCTTT
ACCATTTATTAGTTATGGAGGTTCATCTCTTATTACTAATTTTGTAGCAATGGGATTAGTTTTAAATGTAGGGTTAAGGC
ATAAACCTATTAATTTTTTCAAAGGTAGCATAAATAATTAA

Upstream 100 bases:

>100_bases
ATTGGGAAGCGATGCAGATAGTTTAGTATTGTAAATTAATAGAAAATTTAGTGCTGTTAAATTTAGGTGATTTAATAAAG
TGTAGAAAGTTGGTGTACTA

Downstream 100 bases:

>100_bases
CTATGTAATAAGAAGGTGTCCCAAGATAAACAGAGTTCTTGGCTTCAGAGGGAGTTTTTATTCCCCTGAAGCTTAGAAAT
CGTTATCCAGGGACGTAGCC

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MIRRKNANLNKSFNLKRHIKYFDIFLFAVVILISILGIVMISSATSNFENSKKYIITQILSLAIGLVFMFITIYIDYRNI
GRAYKIIYIFNFLLLAGVILLGTGKDQWGAQRWIRIGGIGIQPSEIAKIGFIITFAKFLELIKDDLNKIKYLLAAFCYIG
VPIILVMIQPDLGTALSFVFISIAMLYICGIDYKYILGGFLACIVIIPIAWQYVLKAYQKNRILIFINPDSDPMGGGYHV
LQSKIAVGSGEFFGTGLFKGSHAQNFLPEKHTDFIFALIGEELGFIGSIIVVLLLLIIVLRCISIAKSAKDNLGCYICVG
VASMIIFQTFINIGMCIGIMPVTGIPLPFISYGGSSLITNFVAMGLVLNVGLRHKPINFFKGSINN

Sequences:

>Translated_386_residues
MIRRKNANLNKSFNLKRHIKYFDIFLFAVVILISILGIVMISSATSNFENSKKYIITQILSLAIGLVFMFITIYIDYRNI
GRAYKIIYIFNFLLLAGVILLGTGKDQWGAQRWIRIGGIGIQPSEIAKIGFIITFAKFLELIKDDLNKIKYLLAAFCYIG
VPIILVMIQPDLGTALSFVFISIAMLYICGIDYKYILGGFLACIVIIPIAWQYVLKAYQKNRILIFINPDSDPMGGGYHV
LQSKIAVGSGEFFGTGLFKGSHAQNFLPEKHTDFIFALIGEELGFIGSIIVVLLLLIIVLRCISIAKSAKDNLGCYICVG
VASMIIFQTFINIGMCIGIMPVTGIPLPFISYGGSSLITNFVAMGLVLNVGLRHKPINFFKGSINN
>Mature_386_residues
MIRRKNANLNKSFNLKRHIKYFDIFLFAVVILISILGIVMISSATSNFENSKKYIITQILSLAIGLVFMFITIYIDYRNI
GRAYKIIYIFNFLLLAGVILLGTGKDQWGAQRWIRIGGIGIQPSEIAKIGFIITFAKFLELIKDDLNKIKYLLAAFCYIG
VPIILVMIQPDLGTALSFVFISIAMLYICGIDYKYILGGFLACIVIIPIAWQYVLKAYQKNRILIFINPDSDPMGGGYHV
LQSKIAVGSGEFFGTGLFKGSHAQNFLPEKHTDFIFALIGEELGFIGSIIVVLLLLIIVLRCISIAKSAKDNLGCYICVG
VASMIIFQTFINIGMCIGIMPVTGIPLPFISYGGSSLITNFVAMGLVLNVGLRHKPINFFKGSINN

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=374, Percent_Identity=35.5614973262032, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1786277, Length=377, Percent_Identity=29.7082228116711, Blast_Score=170, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 42823; Mature: 42823

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRKNANLNKSFNLKRHIKYFDIFLFAVVILISILGIVMISSATSNFENSKKYIITQIL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
SLAIGLVFMFITIYIDYRNIGRAYKIIYIFNFLLLAGVILLGTGKDQWGAQRWIRIGGIG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEECCCC
IQPSEIAKIGFIITFAKFLELIKDDLNKIKYLLAAFCYIGVPIILVMIQPDLGTALSFVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHH
ISIAMLYICGIDYKYILGGFLACIVIIPIAWQYVLKAYQKNRILIFINPDSDPMGGGYHV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHH
LQSKIAVGSGEFFGTGLFKGSHAQNFLPEKHTDFIFALIGEELGFIGSIIVVLLLLIIVL
HHHHHHCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RCISIAKSAKDNLGCYICVGVASMIIFQTFINIGMCIGIMPVTGIPLPFISYGGSSLITN
HHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHH
FVAMGLVLNVGLRHKPINFFKGSINN
HHHHHHHHHCCCCCCCCHHHCCCCCC
>Mature Secondary Structure
MIRRKNANLNKSFNLKRHIKYFDIFLFAVVILISILGIVMISSATSNFENSKKYIITQIL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
SLAIGLVFMFITIYIDYRNIGRAYKIIYIFNFLLLAGVILLGTGKDQWGAQRWIRIGGIG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEECCCC
IQPSEIAKIGFIITFAKFLELIKDDLNKIKYLLAAFCYIGVPIILVMIQPDLGTALSFVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHH
ISIAMLYICGIDYKYILGGFLACIVIIPIAWQYVLKAYQKNRILIFINPDSDPMGGGYHV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHH
LQSKIAVGSGEFFGTGLFKGSHAQNFLPEKHTDFIFALIGEELGFIGSIIVVLLLLIIVL
HHHHHHCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RCISIAKSAKDNLGCYICVGVASMIIFQTFINIGMCIGIMPVTGIPLPFISYGGSSLITN
HHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHH
FVAMGLVLNVGLRHKPINFFKGSINN
HHHHHHHHHCCCCCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]