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The map label for this gene is plsC [H]

Identifier: 226947652

GI number: 226947652

Start: 534717

End: 535439

Strand: Direct

Name: plsC [H]

Synonym: CLM_0495

Alternate gene names: 226947652

Gene position: 534717-535439 (Clockwise)

Preceding gene: 226947648

Following gene: 226947653

Centisome position: 12.87

GC content: 29.74

Gene sequence:

>723_bases
ATGAAGTCATTTATTTTTTATTTAGGTTTTGGATTTTATATGCTACTATCCCTTTTAAGAATAATAAAATTAAAATATTT
AAAGAGAAAAGGTAATAAAGAAGAAATAGATAGATATATTAATAAAAGTGTTTTAGGCTGGGCAAATTTCATAGTCAATG
GTATAGGAATAAAAGTAAATAAAAAAGGATTAGAGAATGTACCTGATGGGCCTTGTTTATTTGTAGGAAATCATCAAGGA
TTGTTAGATGTGCCGGTTATAGTTTCATCCCTAGATAGATATGTGGGCTTTGTAGCTAAAAAGGAAATGCTAAAACTTAA
AATATTAACTTACTGGATGAAAGAAATGAAATGTGTTTTTATGGATAGACAAAACGTTAGAGCAGCAGTAAAGACCATAA
ATGAAGGTGTAGAAAATTTAAAAAATGGATATAGCATGCTGATATTCCCAGAAGGTACAAGAAGTAGAGGAGAAAATTTA
GGGGAATTTAAAAAGGGAAGTATGAAATTAGGTATAAAAGCAGGGGTACCAATAGTGCCTATAGCTATTAATGGTACCTA
TAATGTACTGGAGGCCAATGGAAGAAAGATAAAAGCCGCGGATGTAGATTTAATAATATGTCCACCGATATATCCTAATG
AACTCTCTAAAGAGGAACAAAATAATTTATCTCAAACTATTAAAGATATTATACAAAAGGAACTAGAAAAAGCAAGAAAT
TAA

Upstream 100 bases:

>100_bases
CATTATTTAATTCTAACATAAATTAACCAAAAGTAGATAAGTTTTTTTATATATATTATAATAATAAAGTGAAGTTACAT
AATAAAAGGAGAGAATTATA

Downstream 100 bases:

>100_bases
GAGGAGAGTGTCTCAAAATAGATTTAATTTTGAGACATTCTCTTCTTTTTTTATTATTAAGTGATTCTTAGTTAAGGTGG
ACTTTTATTAGAATAATTAT

Product: putative 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MKSFIFYLGFGFYMLLSLLRIIKLKYLKRKGNKEEIDRYINKSVLGWANFIVNGIGIKVNKKGLENVPDGPCLFVGNHQG
LLDVPVIVSSLDRYVGFVAKKEMLKLKILTYWMKEMKCVFMDRQNVRAAVKTINEGVENLKNGYSMLIFPEGTRSRGENL
GEFKKGSMKLGIKAGVPIVPIAINGTYNVLEANGRKIKAADVDLIICPPIYPNELSKEEQNNLSQTIKDIIQKELEKARN

Sequences:

>Translated_240_residues
MKSFIFYLGFGFYMLLSLLRIIKLKYLKRKGNKEEIDRYINKSVLGWANFIVNGIGIKVNKKGLENVPDGPCLFVGNHQG
LLDVPVIVSSLDRYVGFVAKKEMLKLKILTYWMKEMKCVFMDRQNVRAAVKTINEGVENLKNGYSMLIFPEGTRSRGENL
GEFKKGSMKLGIKAGVPIVPIAINGTYNVLEANGRKIKAADVDLIICPPIYPNELSKEEQNNLSQTIKDIIQKELEKARN
>Mature_240_residues
MKSFIFYLGFGFYMLLSLLRIIKLKYLKRKGNKEEIDRYINKSVLGWANFIVNGIGIKVNKKGLENVPDGPCLFVGNHQG
LLDVPVIVSSLDRYVGFVAKKEMLKLKILTYWMKEMKCVFMDRQNVRAAVKTINEGVENLKNGYSMLIFPEGTRSRGENL
GEFKKGSMKLGIKAGVPIVPIAINGTYNVLEANGRKIKAADVDLIICPPIYPNELSKEEQNNLSQTIKDIIQKELEKARN

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=178, Percent_Identity=26.4044943820225, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI15100175, Length=178, Percent_Identity=26.4044943820225, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI6041665, Length=183, Percent_Identity=27.8688524590164, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789395, Length=186, Percent_Identity=29.5698924731183, Blast_Score=78, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17564032, Length=235, Percent_Identity=22.9787234042553, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320151, Length=178, Percent_Identity=28.6516853932584, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24641614, Length=189, Percent_Identity=25.3968253968254, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24641612, Length=189, Percent_Identity=25.3968253968254, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281364648, Length=188, Percent_Identity=24.468085106383, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24582856, Length=188, Percent_Identity=24.468085106383, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24582854, Length=188, Percent_Identity=24.468085106383, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27149; Mature: 27149

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFIFYLGFGFYMLLSLLRIIKLKYLKRKGNKEEIDRYINKSVLGWANFIVNGIGIKVN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEE
KKGLENVPDGPCLFVGNHQGLLDVPVIVSSLDRYVGFVAKKEMLKLKILTYWMKEMKCVF
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDRQNVRAAVKTINEGVENLKNGYSMLIFPEGTRSRGENLGEFKKGSMKLGIKAGVPIVP
HCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHCCCCEEEEEECCCCEEE
IAINGTYNVLEANGRKIKAADVDLIICPPIYPNELSKEEQNNLSQTIKDIIQKELEKARN
EEECCCEEEEECCCCEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSFIFYLGFGFYMLLSLLRIIKLKYLKRKGNKEEIDRYINKSVLGWANFIVNGIGIKVN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEE
KKGLENVPDGPCLFVGNHQGLLDVPVIVSSLDRYVGFVAKKEMLKLKILTYWMKEMKCVF
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDRQNVRAAVKTINEGVENLKNGYSMLIFPEGTRSRGENLGEFKKGSMKLGIKAGVPIVP
HCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHCCCCEEEEEECCCCEEE
IAINGTYNVLEANGRKIKAADVDLIICPPIYPNELSKEEQNNLSQTIKDIIQKELEKARN
EEECCCEEEEECCCCEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7569993; 8253680 [H]