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The map label for this gene is resE [H]

Identifier: 226947567

GI number: 226947567

Start: 424079

End: 425926

Strand: Direct

Name: resE [H]

Synonym: CLM_0404

Alternate gene names: 226947567

Gene position: 424079-425926 (Clockwise)

Preceding gene: 226947566

Following gene: 226947568

Centisome position: 10.21

GC content: 24.24

Gene sequence:

>1848_bases
ATGAACTTAGATAAAATAGAAATTAGAAATTGGAGTCATGATAAAAAAATATATAATAGCATGTTAATAGTAAAATTCAT
TATACTGCTTTTTTGCGTAGGTGCTATTTATTTAGATTATGCAGAAAAGAATAATAAGAATATTTCTCAAAACTTTTATT
GTAATGCATTAAATCTAGTTATTATAATAATATGTTTAGTTAGTGTATATTTTATTTGGATGTTTATATCAATAAAGGCT
TTTAAATTTGAAAGAATAAAAACAATTCAAGTTATAGAAAATACTATATCAATTGTAATTTTTACATTTATAATAATGAT
GTCGGGAAGCTATAAGAGCTCTTATAAATTTCTATTTTTAGTAGCTATAATCACTGCTACAATACAATTGGGAATGAAAC
ATGGAATTATTACGTCACTTGTATCCTCTATTATAATATTAGCCATAGATCTAATATTAGCACCAAAGGCTCCAGTAAAT
ATATATTTTGAAACAGATTTAATTTTAGTAGGAGTTTTCATAATGACAGCTTGGCCTCTGGGATATTATGTTAATATTCA
AAAGGAAGATCTAAGACAAAAAGAGGAAGAAGTAAATATATTAGCTAATAAATTAGACCAGAAAGAAATGCAAAAAAGAT
GTATGGAGCAATTACTTATAAAAAATGAAAATTGTTATAATTTACTTATAAGAAATTCAAAGGATGCTATATTGGTACAT
AGATATGGTAAGATTATATTTGCTAATGAAAGATTAAAGCAGATGTTAGGATATAGAAAAGAATATAATTTTGAGGATAT
AGATATAAAAAGTTTAATACCTAAAGATGAATATAATACTGTAAAAAATAAGTTGGAAAACTTATATTACGGTAGTGAAA
ATGTAGTTAATTTTCAGCACAATGTAATTAATAATAAAGAGAAGACAATACAAAATACATCTACTTATGTTATATATGAT
GGAATGCCAACAATTTTCAGTATATTACATGATGTAACATCTAAAATACAAGTAGAAAAACTTGAACAAGATGTTAAAAA
GAATATAGAATTGCTAAATGAAAGCAGAGAATATAATAAATTAATTACAGAGTTTTTATCTAATATATCCCATGAGTTAA
AAACTCCTTTAAATGTTATTTTTACAGCAGTGCAATTATTGGGTTTTTATGAAAAGGATGTTGACTATGAAAAACAAGAT
AAATATTTAAAACTAATAAAGCAGAATTGTTATAGGCTTATGAAGTTAATAAATAACCTATTAGATACAACTAAATTAGA
TTCAGGATATTTAAAATTAAATTTAGTTAATTATAATATAGTAAATTTAATAGAAGAAATAACATTATCTGTAACATCCT
ACGCTGAAAGTAAGGGGATAAATATTATATTTGATACAAATGTGGAAGAGAAAATCATTGCTGTTGATACAGATAAAATA
GAAAGAATTATTTTAAATTTACTTTCAAACTCTATAAAGTTTACTAATGCCGGAGGTAATATATTTGTAAATGTAAAAGA
TTGTGGAGAGAATGTATATGTACATGTAAAAGACACGGGAGTTGGTATACCTTCGGATAAATTAGAATCTATATTTGAAA
GATTTTTTCAAGTAGATAAAACTTTAAAGAAAAATAAAGAGGGAACTGGTATAGGATTACATTTAGTAAAATCCTTTGTA
GAAATGCATAATGGTACTGTTACTATAAAAAGTGAATTAGGACAAGGAACAGAATTTATAATAAAGTTACCTGCTGTAGT
TTGTGAGGAACAGATAAAATCAAAAAACATAATTTATGAAGCTAATATAGAACGTATAAATATGGAATTCTCAGATATAA
ACCAATAA

Upstream 100 bases:

>100_bases
ATTTTATTCCTTCATTTACTTTATTTGTATTTAGTGTTTTTACTATGAACAAATTTATAAATAGAGAGGAATAATGTAAA
AATATATAGGAGTTATGTTA

Downstream 100 bases:

>100_bases
TATTATAATTATTTATGAAATAAATTTTTTAAAATTGCATACTACAATTTTAGAGAATTTATTTTATTTTTATCTATTAA
AATTTATATAGACTCACAAG

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MNLDKIEIRNWSHDKKIYNSMLIVKFIILLFCVGAIYLDYAEKNNKNISQNFYCNALNLVIIIICLVSVYFIWMFISIKA
FKFERIKTIQVIENTISIVIFTFIIMMSGSYKSSYKFLFLVAIITATIQLGMKHGIITSLVSSIIILAIDLILAPKAPVN
IYFETDLILVGVFIMTAWPLGYYVNIQKEDLRQKEEEVNILANKLDQKEMQKRCMEQLLIKNENCYNLLIRNSKDAILVH
RYGKIIFANERLKQMLGYRKEYNFEDIDIKSLIPKDEYNTVKNKLENLYYGSENVVNFQHNVINNKEKTIQNTSTYVIYD
GMPTIFSILHDVTSKIQVEKLEQDVKKNIELLNESREYNKLITEFLSNISHELKTPLNVIFTAVQLLGFYEKDVDYEKQD
KYLKLIKQNCYRLMKLINNLLDTTKLDSGYLKLNLVNYNIVNLIEEITLSVTSYAESKGINIIFDTNVEEKIIAVDTDKI
ERIILNLLSNSIKFTNAGGNIFVNVKDCGENVYVHVKDTGVGIPSDKLESIFERFFQVDKTLKKNKEGTGIGLHLVKSFV
EMHNGTVTIKSELGQGTEFIIKLPAVVCEEQIKSKNIIYEANIERINMEFSDINQ

Sequences:

>Translated_615_residues
MNLDKIEIRNWSHDKKIYNSMLIVKFIILLFCVGAIYLDYAEKNNKNISQNFYCNALNLVIIIICLVSVYFIWMFISIKA
FKFERIKTIQVIENTISIVIFTFIIMMSGSYKSSYKFLFLVAIITATIQLGMKHGIITSLVSSIIILAIDLILAPKAPVN
IYFETDLILVGVFIMTAWPLGYYVNIQKEDLRQKEEEVNILANKLDQKEMQKRCMEQLLIKNENCYNLLIRNSKDAILVH
RYGKIIFANERLKQMLGYRKEYNFEDIDIKSLIPKDEYNTVKNKLENLYYGSENVVNFQHNVINNKEKTIQNTSTYVIYD
GMPTIFSILHDVTSKIQVEKLEQDVKKNIELLNESREYNKLITEFLSNISHELKTPLNVIFTAVQLLGFYEKDVDYEKQD
KYLKLIKQNCYRLMKLINNLLDTTKLDSGYLKLNLVNYNIVNLIEEITLSVTSYAESKGINIIFDTNVEEKIIAVDTDKI
ERIILNLLSNSIKFTNAGGNIFVNVKDCGENVYVHVKDTGVGIPSDKLESIFERFFQVDKTLKKNKEGTGIGLHLVKSFV
EMHNGTVTIKSELGQGTEFIIKLPAVVCEEQIKSKNIIYEANIERINMEFSDINQ
>Mature_615_residues
MNLDKIEIRNWSHDKKIYNSMLIVKFIILLFCVGAIYLDYAEKNNKNISQNFYCNALNLVIIIICLVSVYFIWMFISIKA
FKFERIKTIQVIENTISIVIFTFIIMMSGSYKSSYKFLFLVAIITATIQLGMKHGIITSLVSSIIILAIDLILAPKAPVN
IYFETDLILVGVFIMTAWPLGYYVNIQKEDLRQKEEEVNILANKLDQKEMQKRCMEQLLIKNENCYNLLIRNSKDAILVH
RYGKIIFANERLKQMLGYRKEYNFEDIDIKSLIPKDEYNTVKNKLENLYYGSENVVNFQHNVINNKEKTIQNTSTYVIYD
GMPTIFSILHDVTSKIQVEKLEQDVKKNIELLNESREYNKLITEFLSNISHELKTPLNVIFTAVQLLGFYEKDVDYEKQD
KYLKLIKQNCYRLMKLINNLLDTTKLDSGYLKLNLVNYNIVNLIEEITLSVTSYAESKGINIIFDTNVEEKIIAVDTDKI
ERIILNLLSNSIKFTNAGGNIFVNVKDCGENVYVHVKDTGVGIPSDKLESIFERFFQVDKTLKKNKEGTGIGLHLVKSFV
EMHNGTVTIKSELGQGTEFIIKLPAVVCEEQIKSKNIIYEANIERINMEFSDINQ

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=307, Percent_Identity=28.3387622149837, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1789149, Length=285, Percent_Identity=28.4210526315789, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI48994928, Length=236, Percent_Identity=30.9322033898305, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1786912, Length=250, Percent_Identity=28.8, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1786783, Length=256, Percent_Identity=28.90625, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=29.2372881355932, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1788393, Length=253, Percent_Identity=24.5059288537549, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1788713, Length=260, Percent_Identity=25.7692307692308, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081816, Length=259, Percent_Identity=27.7992277992278, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786600, Length=221, Percent_Identity=25.3393665158371, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI87082128, Length=226, Percent_Identity=29.2035398230088, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1790861, Length=243, Percent_Identity=27.5720164609054, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788549, Length=396, Percent_Identity=21.969696969697, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790346, Length=248, Percent_Identity=25.8064516129032, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1790300, Length=232, Percent_Identity=25.4310344827586, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1787374, Length=231, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787894, Length=222, Percent_Identity=26.5765765765766, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788279, Length=267, Percent_Identity=25.4681647940075, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=251, Percent_Identity=29.8804780876494, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71113; Mature: 71113

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDKIEIRNWSHDKKIYNSMLIVKFIILLFCVGAIYLDYAEKNNKNISQNFYCNALNLV
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
IIIICLVSVYFIWMFISIKAFKFERIKTIQVIENTISIVIFTFIIMMSGSYKSSYKFLFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VAIITATIQLGMKHGIITSLVSSIIILAIDLILAPKAPVNIYFETDLILVGVFIMTAWPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCC
GYYVNIQKEDLRQKEEEVNILANKLDQKEMQKRCMEQLLIKNENCYNLLIRNSKDAILVH
CEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEE
RYGKIIFANERLKQMLGYRKEYNFEDIDIKSLIPKDEYNTVKNKLENLYYGSENVVNFQH
ECCCEEEECHHHHHHHCHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEHH
NVINNKEKTIQNTSTYVIYDGMPTIFSILHDVTSKIQVEKLEQDVKKNIELLNESREYNK
HHCCCHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LITEFLSNISHELKTPLNVIFTAVQLLGFYEKDVDYEKQDKYLKLIKQNCYRLMKLINNL
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LDTTKLDSGYLKLNLVNYNIVNLIEEITLSVTSYAESKGINIIFDTNVEEKIIAVDTDKI
HHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECHHHH
ERIILNLLSNSIKFTNAGGNIFVNVKDCGENVYVHVKDTGVGIPSDKLESIFERFFQVDK
HHHHHHHHHCCCEEEECCCEEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHH
TLKKNKEGTGIGLHLVKSFVEMHNGTVTIKSELGQGTEFIIKLPAVVCEEQIKSKNIIYE
HHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEHHHHHHHHHHCCCCEEEE
ANIERINMEFSDINQ
ECCEEEECCHHCCCC
>Mature Secondary Structure
MNLDKIEIRNWSHDKKIYNSMLIVKFIILLFCVGAIYLDYAEKNNKNISQNFYCNALNLV
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
IIIICLVSVYFIWMFISIKAFKFERIKTIQVIENTISIVIFTFIIMMSGSYKSSYKFLFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VAIITATIQLGMKHGIITSLVSSIIILAIDLILAPKAPVNIYFETDLILVGVFIMTAWPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCC
GYYVNIQKEDLRQKEEEVNILANKLDQKEMQKRCMEQLLIKNENCYNLLIRNSKDAILVH
CEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEE
RYGKIIFANERLKQMLGYRKEYNFEDIDIKSLIPKDEYNTVKNKLENLYYGSENVVNFQH
ECCCEEEECHHHHHHHCHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEHH
NVINNKEKTIQNTSTYVIYDGMPTIFSILHDVTSKIQVEKLEQDVKKNIELLNESREYNK
HHCCCHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LITEFLSNISHELKTPLNVIFTAVQLLGFYEKDVDYEKQDKYLKLIKQNCYRLMKLINNL
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LDTTKLDSGYLKLNLVNYNIVNLIEEITLSVTSYAESKGINIIFDTNVEEKIIAVDTDKI
HHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECHHHH
ERIILNLLSNSIKFTNAGGNIFVNVKDCGENVYVHVKDTGVGIPSDKLESIFERFFQVDK
HHHHHHHHHCCCEEEECCCEEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHH
TLKKNKEGTGIGLHLVKSFVEMHNGTVTIKSELGQGTEFIIKLPAVVCEEQIKSKNIIYE
HHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEHHHHHHHHHHCCCCEEEE
ANIERINMEFSDINQ
ECCEEEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]