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The map label for this gene is pagR [H]

Identifier: 226947403

GI number: 226947403

Start: 213491

End: 213772

Strand: Direct

Name: pagR [H]

Synonym: CLM_0230

Alternate gene names: 226947403

Gene position: 213491-213772 (Clockwise)

Preceding gene: 226947402

Following gene: 226947404

Centisome position: 5.14

GC content: 30.14

Gene sequence:

>282_bases
ATGGATAATGATTATGCAAAATATAATGATATAGCAGAACTTCTAAAAGTTTTAGCTCACCCAGTTAGGATATGTATAGT
GAAGGGGCTTTTAGAAAAAGGAGAATGTAATGTAAGTCATATGCAAAATTGCTTAGATATGCCTCAATCTACTATATCTC
AACACTTACAGAAACTAAAAAGTGCAGGGATAATAGAAGGGGATAGAAATGGGCTTCAAATAAATTATCATGTTTCTAAT
AAAAAAGCAGAGCAATTGATAGAAATTTTGCTTAATGAATAA

Upstream 100 bases:

>100_bases
CCGTAAAGATTACTTAAACTTACGGGATTTATTATTGACAATTATATCGTAATAACGTAATATATAAATATAATGATATA
AAATAGAAAGAGGTAGAATA

Downstream 100 bases:

>100_bases
TAGTACTAAGAAATTTCTATTTAAATGGGAGGAATTATAATGAATAAGAAGGTACTAATCATTGGCGGTGTAGCAGGAGG
AGCTTCAGCAGCTGCAAGAC

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: Protective antigen repressor [H]

Number of amino acids: Translated: 93; Mature: 93

Protein sequence:

>93_residues
MDNDYAKYNDIAELLKVLAHPVRICIVKGLLEKGECNVSHMQNCLDMPQSTISQHLQKLKSAGIIEGDRNGLQINYHVSN
KKAEQLIEILLNE

Sequences:

>Translated_93_residues
MDNDYAKYNDIAELLKVLAHPVRICIVKGLLEKGECNVSHMQNCLDMPQSTISQHLQKLKSAGIIEGDRNGLQINYHVSN
KKAEQLIEILLNE
>Mature_93_residues
MDNDYAKYNDIAELLKVLAHPVRICIVKGLLEKGECNVSHMQNCLDMPQSTISQHLQKLKSAGIIEGDRNGLQINYHVSN
KKAEQLIEILLNE

Specific function: Represses the expression of the pagA and atxA genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 10501; Mature: 10501

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNDYAKYNDIAELLKVLAHPVRICIVKGLLEKGECNVSHMQNCLDMPQSTISQHLQKLK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHH
SAGIIEGDRNGLQINYHVSNKKAEQLIEILLNE
HCCCCCCCCCCEEEEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure
MDNDYAKYNDIAELLKVLAHPVRICIVKGLLEKGECNVSHMQNCLDMPQSTISQHLQKLK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHH
SAGIIEGDRNGLQINYHVSNKKAEQLIEILLNE
HCCCCCCCCCCEEEEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10419943; 10515943; 12004073; 12067380; 10475965 [H]