Click here to switch to the map view.

The map label for this gene is ywlE [H]

Identifier: 226947366

GI number: 226947366

Start: 173895

End: 174347

Strand: Direct

Name: ywlE [H]

Synonym: CLM_0186

Alternate gene names: 226947366

Gene position: 173895-174347 (Clockwise)

Preceding gene: 226947365

Following gene: 226947367

Centisome position: 4.18

GC content: 28.04

Gene sequence:

>453_bases
ATGAATATATTATTTGTTTGTACAGGGAATACTTGTAGAAGTTTTATGGCAGAAGCTATATTTAATTCTTTAAATAATAT
GGAAGAGATAACTGCTAAGTCAGCGGGGATAGCTGTGGTGCCTGGAAGTGTTTCATCAAGTAATGCTTGTAAAATAATTA
ATGAAGATATTAATATAGACCTGTCTAACAGAGAAGCAGTTCAATTAGATGAAGAGATATTAGATCAATCAGATTTAATA
TTGACTATGACATATTCAGCTAAAGACTTGCTATCTAATTTATCTTTAGAAGATAGTGATAGGATTTTTTGTATAACTGA
ATATGTAGGACAAAAAGGTGAGATTTTAGATCCCTTTGGTGGAGACATAGAAGTATATAAGAACACTTATGAACAATTAA
AAAATATCATTTTATTATTATTGAAAAAATTAAAAGAAGATAGACAAAACTAA

Upstream 100 bases:

>100_bases
ATCTGAAGCATTTGAAGAAAAAGATATGGGAGTAGCTATAATGAATAGGCTAAAAAAGTCAGCTGGCTATGATATTATAA
ATTTAGATTAGGAGGCACTA

Downstream 100 bases:

>100_bases
TAGGTGGTTTATCTTCTTTTTTTGCAAAAATTAATATAAATAATGCGGAGGTGCTTTAAATGAAAATAGCTTTAGGAAGC
GATCATGCAGGATTACCTTT

Product: low molecular weight protein tyrosine phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MNILFVCTGNTCRSFMAEAIFNSLNNMEEITAKSAGIAVVPGSVSSSNACKIINEDINIDLSNREAVQLDEEILDQSDLI
LTMTYSAKDLLSNLSLEDSDRIFCITEYVGQKGEILDPFGGDIEVYKNTYEQLKNIILLLLKKLKEDRQN

Sequences:

>Translated_150_residues
MNILFVCTGNTCRSFMAEAIFNSLNNMEEITAKSAGIAVVPGSVSSSNACKIINEDINIDLSNREAVQLDEEILDQSDLI
LTMTYSAKDLLSNLSLEDSDRIFCITEYVGQKGEILDPFGGDIEVYKNTYEQLKNIILLLLKKLKEDRQN
>Mature_150_residues
MNILFVCTGNTCRSFMAEAIFNSLNNMEEITAKSAGIAVVPGSVSSSNACKIINEDINIDLSNREAVQLDEEILDQSDLI
LTMTYSAKDLLSNLSLEDSDRIFCITEYVGQKGEILDPFGGDIEVYKNTYEQLKNIILLLLKKLKEDRQN

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16734; Mature: 16734

Theoretical pI: Translated: 4.10; Mature: 4.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILFVCTGNTCRSFMAEAIFNSLNNMEEITAKSAGIAVVPGSVSSSNACKIINEDINID
CCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECCCCEEE
LSNREAVQLDEEILDQSDLILTMTYSAKDLLSNLSLEDSDRIFCITEYVGQKGEILDPFG
ECCCCHHHHHHHHCCCCCEEEEEECCHHHHHHCCCCCCCCCEEEEEHHHCCCCCEECCCC
GDIEVYKNTYEQLKNIILLLLKKLKEDRQN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNILFVCTGNTCRSFMAEAIFNSLNNMEEITAKSAGIAVVPGSVSSSNACKIINEDINID
CCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECCCCEEE
LSNREAVQLDEEILDQSDLILTMTYSAKDLLSNLSLEDSDRIFCITEYVGQKGEILDPFG
ECCCCHHHHHHHHCCCCCEEEEEECCHHHHHHCCCCCCCCCEEEEEHHHCCCCCEECCCC
GDIEVYKNTYEQLKNIILLLLKKLKEDRQN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7798145; 9384377 [H]