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The map label for this gene is feaR [C]

Identifier: 226225370

GI number: 226225370

Start: 2872775

End: 2875117

Strand: Reverse

Name: feaR [C]

Synonym: Lm4b_02793

Alternate gene names: 226225370

Gene position: 2875117-2872775 (Counterclockwise)

Preceding gene: 226225372

Following gene: 226225369

Centisome position: 98.71

GC content: 37.09

Gene sequence:

>2343_bases
GTGTCTCATTTAAAAGATTATACGATTGGTATTCAACATATAAAGCAGCTGACGTCGGAAATATCACTTGGAACTAAATT
GGTATTTGCTATTTCTGGACAAATAACAATCAAGGTTTCTGAGCAAAAATTTTACTTGCAGGAAGGCGATGTTTTAGTTC
TTGATCGCAATACCTTTTATACAATTGAGGGAAATGAAGATAATTTATTTATTAATTTAACGATTTCAGATACATTTTTT
GCGCATTATTATGAGGATTATTTTCAGCATTCTTTTAAATTTTTCTCGAAGGAGAGTGACCCTGGGAGAGAGCGGGTTGT
TGGGTCTTTGAGGAAGTCGGTGAGTGAGCTTTTGATTGCTTCGGCGACGAAGAAACGAGCGAATAAATTAGAAGCGCAAT
CGGCGTTGTTCCAAATTTTATTATTACTTACGCGTTTTTTGAAAAAAGGAATTCCATCTTCTGCTAGGAAAGAAGTCAAT
GATAAACGGATTTCGCGCATTATTCGAGAAGTGGAAGAGCGGTTTGATGAAGCCTTGTCGCTTCGTGAGTTTGCGCAAAA
AGAGTTTTTAAGTGAGGCGTACTTATCACGTTATTTTAAAAAGACGACGGGGCTTGGTTTTTTACAGTATTTGACAGAAG
TCCGATTGAAGCATGCGATTCAAGATTTACTACATTCGGCGGAAAGTATTACAGAGATTGCGTTAAAAAATGGTTTTTCG
AGCCAAAAGCATTTTTCAGAAGTATTTAAGTTTCATTTTGAGCTAACGCCAAGTGAATACCGAGCGGAACATCATGTGGA
AACGAATTTGTTAATAGACAATAAGACATCTGAGCTGGGCGCTAGTATAGAACAAATTGTGCCATCTCCGGAAATTTTAG
TGAAATTGTCACGACTTTATCATGATGTGGAGCCGGGTAAGGAATTAAATAAAGCACCATTTGAGAAAAAGAAAATTGAT
ATCACGGAAAAGACCGAACGTTGTTTAAGTGAGAATATGAATATTTTGACGATTGGTGAGCTTAAAGAAGTGCTTAAAGA
TAATGTCCAAAAGCAGATTATTACGACGCGTGATGAGATTGGGATTAATTATATTGGTATTCGTCATTTGTTTAGAGGTT
CGACGTTCTTGCCTGAAACGGAAACGGACGAATTAGTGCCAACTTCTTCTCCATATGCGAATGCGGATTTAGCGCTCACT
TTTTTAAAACAGCAAAATTTACAATTGTTTATTCGCTTGGAGTATCAAGATATTGTAGGCGATGAGGCGGCTGTTTTTGA
ACGATTGGATCACTTTTTAAAGCATTGTATGCAGGTTTTTGGGCGGGAATTTGTTTCAAAATGGCATTTTATGTTTTTTG
AACCGAAAAATACATATGCTGATAAGGAAGAACTGAAAAAACTTTATTTGAAAATATATCACACTATAAAATCGCGTTTT
CCAGCTATCCAAGTCGGAAATTTTGTCCCATTTTCATTGTCTAAAAATGCAGTGCCTGAACGACATACGTGGTTTTTAGA
AGAAGCGGATAAAATGGACTTTGTCGCCTATAATGCGAATCAAAATGAAGCGGTAGATTTTTCGAAAGAGGATATGAAGT
CGTTTTCGATTTCAGAGGATTATTGTTTGTCAAAAACGCTTCAATTAAAGGCTTTCTTGAAACATCATCATATCAATAAG
CCGCTAATGTTAGTAAACTGGAACACATTATCTGGGAATACGAGATACACAAACGGGACTTTTTTCAGAGGAGCATTAGT
TTTGAAAACGATGCTAGATTTGGTACCAGAAGTGGATGCATTGGGCTTTTGGATTAATACGGAACTTCACGAAGGGGACG
ATAGCAAATTAAATATTAGTCTTGATGGAATTGAAATGTTCCACTTTTTCAATGGTAAACGACCGGCGTTTTATGCTGTG
AAGTTTTTGAGAAGGCTTAAGGGTGTTGTGGTTGCTAAGGGTGAAGATTATATTATGACGAAGCACGCAGACGGTTATCA
GCTTATTTTGATGAACTGTGCGACGATTAATCCGCGTTATTCTGTGGAGGAAAGGTTCATTAAGGAAGAACAAAAAGAAG
TGCATATTAGACTTACAGGGCTTCACGCGGGTGATTATCAAGTCTGTAAATGGCAATTCGACCGTGACAATGGGGCACTT
TATTCGAAGTATTGGCAACTGAACAGTAAGTATGGGCTAGATAAAGAGATTTTGGACTATATTGTGGATGCCTCTCAGCC
TACACTTACGGTGAGTGATGAAACGATTACGGAAGATTGGTCGTTTTATGCTTATTTAGATATTAATGCGATTCATTTTT
ATGAGTTTAGAAGTACGGTTTAA

Upstream 100 bases:

>100_bases
GTTTAATGACTAAAACAATCATAAAAACTGATAGCGATTAATTTTCACGACTATGATAATATAAAAGTGTCCGATTAAGT
TAAACGAAGGGGTGAATCGA

Downstream 100 bases:

>100_bases
AAAGTTCAACTCTAGCAGTTGAGCTTTTTTTGTGACTTCAACACCGGATTTTTGACATTGGTTTGAGTAATTTACAAAAG
AAGAAAATTTCAAGCTAAAA

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 780; Mature: 779

Protein sequence:

>780_residues
MSHLKDYTIGIQHIKQLTSEISLGTKLVFAISGQITIKVSEQKFYLQEGDVLVLDRNTFYTIEGNEDNLFINLTISDTFF
AHYYEDYFQHSFKFFSKESDPGRERVVGSLRKSVSELLIASATKKRANKLEAQSALFQILLLLTRFLKKGIPSSARKEVN
DKRISRIIREVEERFDEALSLREFAQKEFLSEAYLSRYFKKTTGLGFLQYLTEVRLKHAIQDLLHSAESITEIALKNGFS
SQKHFSEVFKFHFELTPSEYRAEHHVETNLLIDNKTSELGASIEQIVPSPEILVKLSRLYHDVEPGKELNKAPFEKKKID
ITEKTERCLSENMNILTIGELKEVLKDNVQKQIITTRDEIGINYIGIRHLFRGSTFLPETETDELVPTSSPYANADLALT
FLKQQNLQLFIRLEYQDIVGDEAAVFERLDHFLKHCMQVFGREFVSKWHFMFFEPKNTYADKEELKKLYLKIYHTIKSRF
PAIQVGNFVPFSLSKNAVPERHTWFLEEADKMDFVAYNANQNEAVDFSKEDMKSFSISEDYCLSKTLQLKAFLKHHHINK
PLMLVNWNTLSGNTRYTNGTFFRGALVLKTMLDLVPEVDALGFWINTELHEGDDSKLNISLDGIEMFHFFNGKRPAFYAV
KFLRRLKGVVVAKGEDYIMTKHADGYQLILMNCATINPRYSVEERFIKEEQKEVHIRLTGLHAGDYQVCKWQFDRDNGAL
YSKYWQLNSKYGLDKEILDYIVDASQPTLTVSDETITEDWSFYAYLDINAIHFYEFRSTV

Sequences:

>Translated_780_residues
MSHLKDYTIGIQHIKQLTSEISLGTKLVFAISGQITIKVSEQKFYLQEGDVLVLDRNTFYTIEGNEDNLFINLTISDTFF
AHYYEDYFQHSFKFFSKESDPGRERVVGSLRKSVSELLIASATKKRANKLEAQSALFQILLLLTRFLKKGIPSSARKEVN
DKRISRIIREVEERFDEALSLREFAQKEFLSEAYLSRYFKKTTGLGFLQYLTEVRLKHAIQDLLHSAESITEIALKNGFS
SQKHFSEVFKFHFELTPSEYRAEHHVETNLLIDNKTSELGASIEQIVPSPEILVKLSRLYHDVEPGKELNKAPFEKKKID
ITEKTERCLSENMNILTIGELKEVLKDNVQKQIITTRDEIGINYIGIRHLFRGSTFLPETETDELVPTSSPYANADLALT
FLKQQNLQLFIRLEYQDIVGDEAAVFERLDHFLKHCMQVFGREFVSKWHFMFFEPKNTYADKEELKKLYLKIYHTIKSRF
PAIQVGNFVPFSLSKNAVPERHTWFLEEADKMDFVAYNANQNEAVDFSKEDMKSFSISEDYCLSKTLQLKAFLKHHHINK
PLMLVNWNTLSGNTRYTNGTFFRGALVLKTMLDLVPEVDALGFWINTELHEGDDSKLNISLDGIEMFHFFNGKRPAFYAV
KFLRRLKGVVVAKGEDYIMTKHADGYQLILMNCATINPRYSVEERFIKEEQKEVHIRLTGLHAGDYQVCKWQFDRDNGAL
YSKYWQLNSKYGLDKEILDYIVDASQPTLTVSDETITEDWSFYAYLDINAIHFYEFRSTV
>Mature_779_residues
SHLKDYTIGIQHIKQLTSEISLGTKLVFAISGQITIKVSEQKFYLQEGDVLVLDRNTFYTIEGNEDNLFINLTISDTFFA
HYYEDYFQHSFKFFSKESDPGRERVVGSLRKSVSELLIASATKKRANKLEAQSALFQILLLLTRFLKKGIPSSARKEVND
KRISRIIREVEERFDEALSLREFAQKEFLSEAYLSRYFKKTTGLGFLQYLTEVRLKHAIQDLLHSAESITEIALKNGFSS
QKHFSEVFKFHFELTPSEYRAEHHVETNLLIDNKTSELGASIEQIVPSPEILVKLSRLYHDVEPGKELNKAPFEKKKIDI
TEKTERCLSENMNILTIGELKEVLKDNVQKQIITTRDEIGINYIGIRHLFRGSTFLPETETDELVPTSSPYANADLALTF
LKQQNLQLFIRLEYQDIVGDEAAVFERLDHFLKHCMQVFGREFVSKWHFMFFEPKNTYADKEELKKLYLKIYHTIKSRFP
AIQVGNFVPFSLSKNAVPERHTWFLEEADKMDFVAYNANQNEAVDFSKEDMKSFSISEDYCLSKTLQLKAFLKHHHINKP
LMLVNWNTLSGNTRYTNGTFFRGALVLKTMLDLVPEVDALGFWINTELHEGDDSKLNISLDGIEMFHFFNGKRPAFYAVK
FLRRLKGVVVAKGEDYIMTKHADGYQLILMNCATINPRYSVEERFIKEEQKEVHIRLTGLHAGDYQVCKWQFDRDNGALY
SKYWQLNSKYGLDKEILDYIVDASQPTLTVSDETITEDWSFYAYLDINAIHFYEFRSTV

Specific function: Positive Regulator Of Tyna/Maoa And Feab/Pada, The Genes For 2-Phenylethylamine Catabolism. [C]

COG id: COG3664

COG function: function code G; Beta-xylosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HTH araC/xylS-type DNA-binding domains [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=237, Percent_Identity=27.8481012658228, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790391, Length=97, Percent_Identity=36.0824742268041, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI171474011, Length=126, Percent_Identity=31.7460317460317, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1790339, Length=161, Percent_Identity=29.1925465838509, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 90643; Mature: 90512

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHLKDYTIGIQHIKQLTSEISLGTKLVFAISGQITIKVSEQKFYLQEGDVLVLDRNTFY
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECEEEEEECCCEEEEECCCEEEEECCEEE
TIEGNEDNLFINLTISDTFFAHYYEDYFQHSFKFFSKESDPGRERVVGSLRKSVSELLIA
EEECCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
SATKKRANKLEAQSALFQILLLLTRFLKKGIPSSARKEVNDKRISRIIREVEERFDEALS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREFAQKEFLSEAYLSRYFKKTTGLGFLQYLTEVRLKHAIQDLLHSAESITEIALKNGFS
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SQKHFSEVFKFHFELTPSEYRAEHHVETNLLIDNKTSELGASIEQIVPSPEILVKLSRLY
CHHHHHHHHHEEEEECCHHHHHHHCCEEEEEEECCCHHHCCHHHHHCCCHHHHHHHHHHH
HDVEPGKELNKAPFEKKKIDITEKTERCLSENMNILTIGELKEVLKDNVQKQIITTRDEI
HCCCCCCCCCCCCCCHHCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCHHHC
GINYIGIRHLFRGSTFLPETETDELVPTSSPYANADLALTFLKQQNLQLFIRLEYQDIVG
CCEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEHHHHCC
DEAAVFERLDHFLKHCMQVFGREFVSKWHFMFFEPKNTYADKEELKKLYLKIYHTIKSRF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC
PAIQVGNFVPFSLSKNAVPERHTWFLEEADKMDFVAYNANQNEAVDFSKEDMKSFSISED
CEEEECCEECCCCCCCCCCCCCEEHHHCCCCCEEEEECCCCCCCCCCCHHHHHHCCCCCC
YCLSKTLQLKAFLKHHHINKPLMLVNWNTLSGNTRYTNGTFFRGALVLKTMLDLVPEVDA
HHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHCCCCC
LGFWINTELHEGDDSKLNISLDGIEMFHFFNGKRPAFYAVKFLRRLKGVVVAKGEDYIMT
CEEEEECEEECCCCCEEEEEECCEEEEEHHCCCCCHHHHHHHHHHHCCEEEECCCCEEEE
KHADGYQLILMNCATINPRYSVEERFIKEEQKEVHIRLTGLHAGDYQVCKWQFDRDNGAL
ECCCCEEEEEEEEEECCCCCCHHHHHHHHHCCEEEEEEEEEECCCCEEEEEEEECCCCCE
YSKYWQLNSKYGLDKEILDYIVDASQPTLTVSDETITEDWSFYAYLDINAIHFYEFRSTV
EHHHHCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEEEECEEEEEEECCCC
>Mature Secondary Structure 
SHLKDYTIGIQHIKQLTSEISLGTKLVFAISGQITIKVSEQKFYLQEGDVLVLDRNTFY
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECEEEEEECCCEEEEECCCEEEEECCEEE
TIEGNEDNLFINLTISDTFFAHYYEDYFQHSFKFFSKESDPGRERVVGSLRKSVSELLIA
EEECCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
SATKKRANKLEAQSALFQILLLLTRFLKKGIPSSARKEVNDKRISRIIREVEERFDEALS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREFAQKEFLSEAYLSRYFKKTTGLGFLQYLTEVRLKHAIQDLLHSAESITEIALKNGFS
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SQKHFSEVFKFHFELTPSEYRAEHHVETNLLIDNKTSELGASIEQIVPSPEILVKLSRLY
CHHHHHHHHHEEEEECCHHHHHHHCCEEEEEEECCCHHHCCHHHHHCCCHHHHHHHHHHH
HDVEPGKELNKAPFEKKKIDITEKTERCLSENMNILTIGELKEVLKDNVQKQIITTRDEI
HCCCCCCCCCCCCCCHHCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCHHHC
GINYIGIRHLFRGSTFLPETETDELVPTSSPYANADLALTFLKQQNLQLFIRLEYQDIVG
CCEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEHHHHCC
DEAAVFERLDHFLKHCMQVFGREFVSKWHFMFFEPKNTYADKEELKKLYLKIYHTIKSRF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC
PAIQVGNFVPFSLSKNAVPERHTWFLEEADKMDFVAYNANQNEAVDFSKEDMKSFSISED
CEEEECCEECCCCCCCCCCCCCEEHHHCCCCCEEEEECCCCCCCCCCCHHHHHHCCCCCC
YCLSKTLQLKAFLKHHHINKPLMLVNWNTLSGNTRYTNGTFFRGALVLKTMLDLVPEVDA
HHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHCCCCC
LGFWINTELHEGDDSKLNISLDGIEMFHFFNGKRPAFYAVKFLRRLKGVVVAKGEDYIMT
CEEEEECEEECCCCCEEEEEECCEEEEEHHCCCCCHHHHHHHHHHHCCEEEECCCCEEEE
KHADGYQLILMNCATINPRYSVEERFIKEEQKEVHIRLTGLHAGDYQVCKWQFDRDNGAL
ECCCCEEEEEEEEEECCCCCCHHHHHHHHHCCEEEEEEEEEECCCCEEEEEEEECCCCCE
YSKYWQLNSKYGLDKEILDYIVDASQPTLTVSDETITEDWSFYAYLDINAIHFYEFRSTV
EHHHHCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEEEECEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12044378 [H]