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The map label for this gene is bglP [H]

Identifier: 226225324

GI number: 226225324

Start: 2826957

End: 2828810

Strand: Reverse

Name: bglP [H]

Synonym: Lm4b_02747

Alternate gene names: 226225324

Gene position: 2828810-2826957 (Counterclockwise)

Preceding gene: 226225325

Following gene: 226225323

Centisome position: 97.12

GC content: 38.24

Gene sequence:

>1854_bases
ATGGACTACAATCAATTAGCAAAAGAAATTTTACAGGCAGTCGGTGGGAAAAATAATGTGAATGAAGTTTATCATTGCAT
TACCAGACTACGGTTTCAATTAAAAGATCAATCGAAAGTAAATGAAAAACAATTAAAAGATTTGGATAAAGTGATGGGGA
CGAATGTTGCGGGGAATCAATTCCAAGTAATTATCGGAAATGACGTGCCTAAAGTGTTTGACGCATTAGTGACAGAAAAT
CCTGCTTGGAAAAACAAAGAAACGACAAATAAAACGACACGGCAAAAAGGAATAAAAGGATTTTTCTCGAATATCTTTGA
TGCACTTTCGGGCGTGTTTGCACCAATTCTTCCTGCGATTGCGGGAGCAGGTTTAATCAAAGGTTTCATGGCATTATTTG
TTTCACTTGGTTGGTTAGCAACAGATACAGAAACTTACCGTATCTTGTTAGCTATCGGTGACGGGGTATTTTACTTCTTG
CCAATTTTAGTTGCTGTAAGTGCCGCGCGTTACTTTAAAGCGAATATGTTTGTCGCGCTTGGAATTGGAGCGGCGCTACT
TTATCCGGATTTAACGGCTTTACTTAGTGCGGGGACAACGCCACACTTTATCGGGTTACCAGTAACTCCAGTGACGTATG
CTTACTCTGTTATTCCGATTTTACTTGCAATTTGGATTATGTCTTATGTGGAAAAATGGGTGGACCGGATTATTCCAACC
TCGTTAAAACTGTTGTTTGTCCCATTAATTACAATGTTTATTGTTGTTCCTTTGACGCTTGTTGTTATTGGGCCACTAGG
TACATTTGTTGGAGACGGTGTATCTGGCGGAATTAACTGGTTATTAAATAATGGTGGAGTTATTGGCGGTATCTTGATTG
GTGGTGCCATGGCCATTATCGTTATGACTGGTATGCACTATGCAATTGTTCCATTTGTTATTAGTAATTTAGCAAAATAT
GGTTATGATAAATTTTTACCGTTAACTTATATTTCCAATATGAGCCAAGCAGGAGCGACTTTCGGTGTATTTTTCCGGGC
AAAAGATAAAAAACTGAAATCATTAGCATTTTCAACTGGTTTAACTGCATTAATGGGTGTCACGGAACCGGCAATGTACG
GGATAAATGTGGTATATAAACGTCCTTTCATGGCGTCGTTAATTGGTGGGGCTGCTGGTGGTGGCTTTGCAATGATGTTT
GGTGTAAAAGCGTATGTCTTAACTGGTAACGGTGGTATTCCTGGACTTCCAGGTCTTGTCGGAGATACTTTTGTTTATGC
ATTAATTGCGATGGCCTTAGCATTTATCGTGGCTTTAATTTTCTCTTATATTTTCGGTATTGATGAGCAAATAGTAGAAG
CAACTCCTGTAGCAGAAAAAATAGCAGCTGGGACAGAAGTTTTGCAAGCTCCAGTTACTGGTGAATTAGTAAAAATGAGC
CAAGTAAATGATACTACTTTTGCAGATGAAATTATGGGTAAAAGTATTGCGATTAAGCCAAATGAAGGTAAACTTTATGC
TCCAGCTAACGGCACAATCATTTCGCTTTTCAAAACAAAACATGCGATTGCTATGCAGTCAGATAATGGCGCTGAAATAT
TATTACATGTAGGCATTGATACAGTGAAGCTTGATGGTAATTACTTCACGGCACATGTTGCGACGGGTGATGTAGTGGAA
CAAGGAGATTTATTAGTAACGTTTGATATGGAAAAAATTGCAGAAAAATATGATACAACAACGATGATGGTAATTACAAA
TACTAATGAATATGCTTTGGTAGAAGCTAAGGATAGTGGAACGGTAACGAAAGGGAATCAAGTAATGGAATTAAGGAGTG
AGCAAAATGAGTAA

Upstream 100 bases:

>100_bases
ATAGGCTTGTTACCGCGATTTGCGGGCAATACCTGGATGATTGTATGCTTTTTTAGGTGCATTTCATTCAGGTTTTTCTA
TTATATTTAGGAGGATTAGC

Downstream 100 bases:

>100_bases
TACGAAGTTTCCAGATGGCTTTATGTGGGGCGGGGCGACCGCGGCTAACCAGTTTGAAGGTGGTTATAATTCAGGCGGAA
AAGGGCTTGCCTGTGCGGAT

Product: PTS beta-glucoside-specific enzyme II ABC

Products: NA

Alternate protein names: EIIBCA-Bgl; EII-Bgl; Beta-glucoside-specific phosphotransferase enzyme IIB component; PTS system beta-glucoside-specific EIIB component; Beta-glucoside permease IIC component; PTS system beta-glucoside-specific EIIC component; Beta-glucoside-specific phosphotransferase enzyme IIA component; PTS system beta-glucoside-specific EIIA component [H]

Number of amino acids: Translated: 617; Mature: 617

Protein sequence:

>617_residues
MDYNQLAKEILQAVGGKNNVNEVYHCITRLRFQLKDQSKVNEKQLKDLDKVMGTNVAGNQFQVIIGNDVPKVFDALVTEN
PAWKNKETTNKTTRQKGIKGFFSNIFDALSGVFAPILPAIAGAGLIKGFMALFVSLGWLATDTETYRILLAIGDGVFYFL
PILVAVSAARYFKANMFVALGIGAALLYPDLTALLSAGTTPHFIGLPVTPVTYAYSVIPILLAIWIMSYVEKWVDRIIPT
SLKLLFVPLITMFIVVPLTLVVIGPLGTFVGDGVSGGINWLLNNGGVIGGILIGGAMAIIVMTGMHYAIVPFVISNLAKY
GYDKFLPLTYISNMSQAGATFGVFFRAKDKKLKSLAFSTGLTALMGVTEPAMYGINVVYKRPFMASLIGGAAGGGFAMMF
GVKAYVLTGNGGIPGLPGLVGDTFVYALIAMALAFIVALIFSYIFGIDEQIVEATPVAEKIAAGTEVLQAPVTGELVKMS
QVNDTTFADEIMGKSIAIKPNEGKLYAPANGTIISLFKTKHAIAMQSDNGAEILLHVGIDTVKLDGNYFTAHVATGDVVE
QGDLLVTFDMEKIAEKYDTTTMMVITNTNEYALVEAKDSGTVTKGNQVMELRSEQNE

Sequences:

>Translated_617_residues
MDYNQLAKEILQAVGGKNNVNEVYHCITRLRFQLKDQSKVNEKQLKDLDKVMGTNVAGNQFQVIIGNDVPKVFDALVTEN
PAWKNKETTNKTTRQKGIKGFFSNIFDALSGVFAPILPAIAGAGLIKGFMALFVSLGWLATDTETYRILLAIGDGVFYFL
PILVAVSAARYFKANMFVALGIGAALLYPDLTALLSAGTTPHFIGLPVTPVTYAYSVIPILLAIWIMSYVEKWVDRIIPT
SLKLLFVPLITMFIVVPLTLVVIGPLGTFVGDGVSGGINWLLNNGGVIGGILIGGAMAIIVMTGMHYAIVPFVISNLAKY
GYDKFLPLTYISNMSQAGATFGVFFRAKDKKLKSLAFSTGLTALMGVTEPAMYGINVVYKRPFMASLIGGAAGGGFAMMF
GVKAYVLTGNGGIPGLPGLVGDTFVYALIAMALAFIVALIFSYIFGIDEQIVEATPVAEKIAAGTEVLQAPVTGELVKMS
QVNDTTFADEIMGKSIAIKPNEGKLYAPANGTIISLFKTKHAIAMQSDNGAEILLHVGIDTVKLDGNYFTAHVATGDVVE
QGDLLVTFDMEKIAEKYDTTTMMVITNTNEYALVEAKDSGTVTKGNQVMELRSEQNE
>Mature_617_residues
MDYNQLAKEILQAVGGKNNVNEVYHCITRLRFQLKDQSKVNEKQLKDLDKVMGTNVAGNQFQVIIGNDVPKVFDALVTEN
PAWKNKETTNKTTRQKGIKGFFSNIFDALSGVFAPILPAIAGAGLIKGFMALFVSLGWLATDTETYRILLAIGDGVFYFL
PILVAVSAARYFKANMFVALGIGAALLYPDLTALLSAGTTPHFIGLPVTPVTYAYSVIPILLAIWIMSYVEKWVDRIIPT
SLKLLFVPLITMFIVVPLTLVVIGPLGTFVGDGVSGGINWLLNNGGVIGGILIGGAMAIIVMTGMHYAIVPFVISNLAKY
GYDKFLPLTYISNMSQAGATFGVFFRAKDKKLKSLAFSTGLTALMGVTEPAMYGINVVYKRPFMASLIGGAAGGGFAMMF
GVKAYVLTGNGGIPGLPGLVGDTFVYALIAMALAFIVALIFSYIFGIDEQIVEATPVAEKIAAGTEVLQAPVTGELVKMS
QVNDTTFADEIMGKSIAIKPNEGKLYAPANGTIISLFKTKHAIAMQSDNGAEILLHVGIDTVKLDGNYFTAHVATGDVVE
QGDLLVTFDMEKIAEKYDTTTMMVITNTNEYALVEAKDSGTVTKGNQVMELRSEQNE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790159, Length=627, Percent_Identity=35.725677830941, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI48994906, Length=468, Percent_Identity=32.9059829059829, Blast_Score=262, Evalue=6e-71,
Organism=Escherichia coli, GI2367362, Length=428, Percent_Identity=31.0747663551402, Blast_Score=195, Evalue=7e-51,
Organism=Escherichia coli, GI1788769, Length=478, Percent_Identity=27.8242677824268, Blast_Score=143, Evalue=4e-35,
Organism=Escherichia coli, GI1788757, Length=149, Percent_Identity=41.6107382550336, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1786894, Length=155, Percent_Identity=33.5483870967742, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011297 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 66280; Mature: 66280

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYNQLAKEILQAVGGKNNVNEVYHCITRLRFQLKDQSKVNEKQLKDLDKVMGTNVAGNQ
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCE
FQVIIGNDVPKVFDALVTENPAWKNKETTNKTTRQKGIKGFFSNIFDALSGVFAPILPAI
EEEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGAGLIKGFMALFVSLGWLATDTETYRILLAIGDGVFYFLPILVAVSAARYFKANMFVAL
HHHHHHHHHHHHHHHHCCCEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCEEEEE
GIGAALLYPDLTALLSAGTTPHFIGLPVTPVTYAYSVIPILLAIWIMSYVEKWVDRIIPT
HHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
SLKLLFVPLITMFIVVPLTLVVIGPLGTFVGDGVSGGINWLLNNGGVIGGILIGGAMAII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEHHHHHHHHHHHH
VMTGMHYAIVPFVISNLAKYGYDKFLPLTYISNMSQAGATFGVFFRAKDKKLKSLAFSTG
HHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCHHHCCCEEEEEEEECHHHHHHHHHHHH
LTALMGVTEPAMYGINVVYKRPFMASLIGGAAGGGFAMMFGVKAYVLTGNGGIPGLPGLV
HHHHHCCCCCHHHCCEEEECCCHHHHHHCCCCCCCHHEEECCEEEEEECCCCCCCCCCHH
GDTFVYALIAMALAFIVALIFSYIFGIDEQIVEATPVAEKIAAGTEVLQAPVTGELVKMS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHCCHHHHHCCCCCHHEEEC
QVNDTTFADEIMGKSIAIKPNEGKLYAPANGTIISLFKTKHAIAMQSDNGAEILLHVGID
CCCCCHHHHHHCCCEEEEECCCCEEEECCCCCEEEEEECCCEEEEECCCCCEEEEEECCE
TVKLDGNYFTAHVATGDVVEQGDLLVTFDMEKIAEKYDTTTMMVITNTNEYALVEAKDSG
EEEECCCEEEEEEECCCEECCCCEEEEECHHHHHHHHCCEEEEEEECCCCEEEEEECCCC
TVTKGNQVMELRSEQNE
CEECCCHHHHHHHCCCC
>Mature Secondary Structure
MDYNQLAKEILQAVGGKNNVNEVYHCITRLRFQLKDQSKVNEKQLKDLDKVMGTNVAGNQ
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCE
FQVIIGNDVPKVFDALVTENPAWKNKETTNKTTRQKGIKGFFSNIFDALSGVFAPILPAI
EEEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGAGLIKGFMALFVSLGWLATDTETYRILLAIGDGVFYFLPILVAVSAARYFKANMFVAL
HHHHHHHHHHHHHHHHCCCEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCEEEEE
GIGAALLYPDLTALLSAGTTPHFIGLPVTPVTYAYSVIPILLAIWIMSYVEKWVDRIIPT
HHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
SLKLLFVPLITMFIVVPLTLVVIGPLGTFVGDGVSGGINWLLNNGGVIGGILIGGAMAII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEHHHHHHHHHHHH
VMTGMHYAIVPFVISNLAKYGYDKFLPLTYISNMSQAGATFGVFFRAKDKKLKSLAFSTG
HHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCHHHCCCEEEEEEEECHHHHHHHHHHHH
LTALMGVTEPAMYGINVVYKRPFMASLIGGAAGGGFAMMFGVKAYVLTGNGGIPGLPGLV
HHHHHCCCCCHHHCCEEEECCCHHHHHHCCCCCCCHHEEECCEEEEEECCCCCCCCCCHH
GDTFVYALIAMALAFIVALIFSYIFGIDEQIVEATPVAEKIAAGTEVLQAPVTGELVKMS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHCCHHHHHCCCCCHHEEEC
QVNDTTFADEIMGKSIAIKPNEGKLYAPANGTIISLFKTKHAIAMQSDNGAEILLHVGID
CCCCCHHHHHHCCCEEEEECCCCEEEECCCCCEEEEEECCCEEEEECCCCCEEEEEECCE
TVKLDGNYFTAHVATGDVVEQGDLLVTFDMEKIAEKYDTTTMMVITNTNEYALVEAKDSG
EEEECCCEEEEEEECCCEECCCCEEEEECHHHHHHHHCCEEEEEEECCCCEEEEEECCCC
TVTKGNQVMELRSEQNE
CEECCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7883710; 7704263; 9384377; 8628237 [H]