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The map label for this gene is bglC [H]

Identifier: 226225313

GI number: 226225313

Start: 2814943

End: 2816397

Strand: Direct

Name: bglC [H]

Synonym: Lm4b_02736

Alternate gene names: 226225313

Gene position: 2814943-2816397 (Clockwise)

Preceding gene: 226225305

Following gene: 226225314

Centisome position: 96.64

GC content: 42.34

Gene sequence:

>1455_bases
ATGGAACATAATAAGTTGAAACCTTTCCCAAAAGATTTTCTATGGGGATCAGCTTCTGCAGCGTACCAAGTAGAAGGTGC
CTGGGATGAGGATGGTAAAGGACCATCTGTATGGGATGAATTTGTTCGTATTCCTGGAACAACATTCAAAGAAACAAACG
GAGATGTAGCGGTGGATAATTACCATCGTTATAAAGAAGATGTCGCACTAATGGCTGAACAGGGCCTAAAAGCATATCGT
TTCTCTGTCGCATGGAGTCGCGTTATCCCGCATGGTAACGGGGAAGTTAACGAAGCAGGACTTAAATTCTATGATAATTT
GATTGATGAACTTCTTTCTTATGGAATTGAGCCAGTCGTTACACTTTATCACTGGGATATTCCGCAAGGGCTTCAAGACG
AATATGGTGGATGGGAGTCGCGAAAAGTCGTAGAAGATTTCACTAACTACGCTGCCCTTCTATTCAAACGCTTTAACGGC
CGAGTTAAATACTGGGTAACACTTAATGAACAGAACGTATTTATCTCACACGGTTACAAATTAGCGTATCACCCACCTGG
CGTTTCTGACGACAAGCGTATGTTTGCGGCAAATCACAATGCGAACTTGGCGAATGCTTCTGCAATTGCTAAATTCCGCG
AGCTAGGTACATCCGGAAAAATTGGACCAAGTTTTGCTTATGGACCAAGTTACTCCATCGATGCTAACCCAGCAAATGTA
TTAGCTTCTGAAAACTCCGAAGAATTCAATGCCCATTTCTGGATGGATGTTTACACATGGGGTGAATATCCGACTGCTAC
TTGGAACTGGCTGGAAGAGCACGGTCTTGCACCGGAAATCTTACCAGGCGATACGGAGCTTCTGAAAAAAGGAAAACCTG
ATTTCATGGGAGTTAACTATTACCGCTCAATGACTCATGCATTTAATGGGAAAGACGGCGTTGGTTCTGGGAAAATGAAT
ACAACTGGCGAAAAAGGCACTTCCGAGGAAACTGGTGTACCGGGGTTATACAAAAACACCAATAATCCATACTTAGAGAA
AACGAATTGGGACTGGGATATTGATCCAACTGGCTTGCGCATTGGCTTACGTAGAATTACTAACCGCTATAAATTACCAA
TCATGATTACAGAAAATGGTCTTGGTGAGTATGATAGCTTGACGGAAGACCATAAAATCCATGATGAGTACCGAATTGAA
TACATTCGCGCGCATGCTCTAGCAATCCAAGAAGCAATCACGGACGGCGTAGAGATGCTCGGTTACTGCACTTGGAGCTT
CACAGATTTACTAAGCTGGTTAAACGGCTACCAAAAACGTTACGGTTTCGTATATGTAGACCGCGACGAAAACGATGAAA
AAGAATTAAAACGCTATAAAAAAGATAGTTTTTACTGGTATAAAAAGACCATCGAAGCAAACGGAGCTAATTTAGTAGAA
GAACAGGGCAAATAA

Upstream 100 bases:

>100_bases
AGCACCAAAATCTATTTACCAATTAGTCGAAACCGTTTACATTAATAAGGCAAGCAAAACTAAAACAGACTAATCGCACA
TAATTTTTGGAGGTGCCATA

Downstream 100 bases:

>100_bases
GCCTTGTTCTCTCTGCTTCAACCATTTTGGGAGGGAAATTTTAATGAAAAAAATATTACTTGTATGTGCGGCCGGAATGT
CGACAAGCTTACTCGTTACT

Product: beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MEHNKLKPFPKDFLWGSASAAYQVEGAWDEDGKGPSVWDEFVRIPGTTFKETNGDVAVDNYHRYKEDVALMAEQGLKAYR
FSVAWSRVIPHGNGEVNEAGLKFYDNLIDELLSYGIEPVVTLYHWDIPQGLQDEYGGWESRKVVEDFTNYAALLFKRFNG
RVKYWVTLNEQNVFISHGYKLAYHPPGVSDDKRMFAANHNANLANASAIAKFRELGTSGKIGPSFAYGPSYSIDANPANV
LASENSEEFNAHFWMDVYTWGEYPTATWNWLEEHGLAPEILPGDTELLKKGKPDFMGVNYYRSMTHAFNGKDGVGSGKMN
TTGEKGTSEETGVPGLYKNTNNPYLEKTNWDWDIDPTGLRIGLRRITNRYKLPIMITENGLGEYDSLTEDHKIHDEYRIE
YIRAHALAIQEAITDGVEMLGYCTWSFTDLLSWLNGYQKRYGFVYVDRDENDEKELKRYKKDSFYWYKKTIEANGANLVE
EQGK

Sequences:

>Translated_484_residues
MEHNKLKPFPKDFLWGSASAAYQVEGAWDEDGKGPSVWDEFVRIPGTTFKETNGDVAVDNYHRYKEDVALMAEQGLKAYR
FSVAWSRVIPHGNGEVNEAGLKFYDNLIDELLSYGIEPVVTLYHWDIPQGLQDEYGGWESRKVVEDFTNYAALLFKRFNG
RVKYWVTLNEQNVFISHGYKLAYHPPGVSDDKRMFAANHNANLANASAIAKFRELGTSGKIGPSFAYGPSYSIDANPANV
LASENSEEFNAHFWMDVYTWGEYPTATWNWLEEHGLAPEILPGDTELLKKGKPDFMGVNYYRSMTHAFNGKDGVGSGKMN
TTGEKGTSEETGVPGLYKNTNNPYLEKTNWDWDIDPTGLRIGLRRITNRYKLPIMITENGLGEYDSLTEDHKIHDEYRIE
YIRAHALAIQEAITDGVEMLGYCTWSFTDLLSWLNGYQKRYGFVYVDRDENDEKELKRYKKDSFYWYKKTIEANGANLVE
EQGK
>Mature_484_residues
MEHNKLKPFPKDFLWGSASAAYQVEGAWDEDGKGPSVWDEFVRIPGTTFKETNGDVAVDNYHRYKEDVALMAEQGLKAYR
FSVAWSRVIPHGNGEVNEAGLKFYDNLIDELLSYGIEPVVTLYHWDIPQGLQDEYGGWESRKVVEDFTNYAALLFKRFNG
RVKYWVTLNEQNVFISHGYKLAYHPPGVSDDKRMFAANHNANLANASAIAKFRELGTSGKIGPSFAYGPSYSIDANPANV
LASENSEEFNAHFWMDVYTWGEYPTATWNWLEEHGLAPEILPGDTELLKKGKPDFMGVNYYRSMTHAFNGKDGVGSGKMN
TTGEKGTSEETGVPGLYKNTNNPYLEKTNWDWDIDPTGLRIGLRRITNRYKLPIMITENGLGEYDSLTEDHKIHDEYRIE
YIRAHALAIQEAITDGVEMLGYCTWSFTDLLSWLNGYQKRYGFVYVDRDENDEKELKRYKKDSFYWYKKTIEANGANLVE
EQGK

Specific function: Is able to catalyze the hydrolysis of aryl-phospho-beta- D-glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=486, Percent_Identity=34.5679012345679, Blast_Score=249, Evalue=5e-66,
Organism=Homo sapiens, GI32481206, Length=487, Percent_Identity=33.264887063655, Blast_Score=241, Evalue=9e-64,
Organism=Homo sapiens, GI13273313, Length=485, Percent_Identity=33.8144329896907, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI24497614, Length=497, Percent_Identity=31.7907444668008, Blast_Score=196, Evalue=5e-50,
Organism=Homo sapiens, GI28376633, Length=493, Percent_Identity=30.2231237322515, Blast_Score=189, Evalue=6e-48,
Organism=Homo sapiens, GI190360571, Length=97, Percent_Identity=47.4226804123711, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI2367174, Length=490, Percent_Identity=38.9795918367347, Blast_Score=342, Evalue=3e-95,
Organism=Escherichia coli, GI1789070, Length=492, Percent_Identity=38.6178861788618, Blast_Score=327, Evalue=1e-90,
Organism=Escherichia coli, GI2367270, Length=488, Percent_Identity=39.1393442622951, Blast_Score=327, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI17552856, Length=480, Percent_Identity=30.4166666666667, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17539390, Length=471, Percent_Identity=28.8747346072187, Blast_Score=194, Evalue=7e-50,
Organism=Drosophila melanogaster, GI21356577, Length=486, Percent_Identity=31.2757201646091, Blast_Score=221, Evalue=8e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 55330; Mature: 55330

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHNKLKPFPKDFLWGSASAAYQVEGAWDEDGKGPSVWDEFVRIPGTTFKETNGDVAVDN
CCCCCCCCCCHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCEECCCCCEEECC
YHRYKEDVALMAEQGLKAYRFSVAWSRVIPHGNGEVNEAGLKFYDNLIDELLSYGIEPVV
HHHHHHHHHHHHHCCCHHEEHHEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
TLYHWDIPQGLQDEYGGWESRKVVEDFTNYAALLFKRFNGRVKYWVTLNEQNVFISHGYK
EEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCEE
LAYHPPGVSDDKRMFAANHNANLANASAIAKFRELGTSGKIGPSFAYGPSYSIDANPANV
EEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHE
LASENSEEFNAHFWMDVYTWGEYPTATWNWLEEHGLAPEILPGDTELLKKGKPDFMGVNY
EECCCCCCCCEEEEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCHHH
YRSMTHAFNGKDGVGSGKMNTTGEKGTSEETGVPGLYKNTNNPYLEKTNWDWDIDPTGLR
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEECCCCCCCCCCCHHH
IGLRRITNRYKLPIMITENGLGEYDSLTEDHKIHDEYRIEYIRAHALAIQEAITDGVEML
HHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GYCTWSFTDLLSWLNGYQKRYGFVYVDRDENDEKELKRYKKDSFYWYKKTIEANGANLVE
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHCCCEEEEEEEEECCCCHHHH
EQGK
CCCC
>Mature Secondary Structure
MEHNKLKPFPKDFLWGSASAAYQVEGAWDEDGKGPSVWDEFVRIPGTTFKETNGDVAVDN
CCCCCCCCCCHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCEECCCCCEEECC
YHRYKEDVALMAEQGLKAYRFSVAWSRVIPHGNGEVNEAGLKFYDNLIDELLSYGIEPVV
HHHHHHHHHHHHHCCCHHEEHHEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
TLYHWDIPQGLQDEYGGWESRKVVEDFTNYAALLFKRFNGRVKYWVTLNEQNVFISHGYK
EEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCEE
LAYHPPGVSDDKRMFAANHNANLANASAIAKFRELGTSGKIGPSFAYGPSYSIDANPANV
EEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHE
LASENSEEFNAHFWMDVYTWGEYPTATWNWLEEHGLAPEILPGDTELLKKGKPDFMGVNY
EECCCCCCCCEEEEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCHHH
YRSMTHAFNGKDGVGSGKMNTTGEKGTSEETGVPGLYKNTNNPYLEKTNWDWDIDPTGLR
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEECCCCCCCCCCCHHH
IGLRRITNRYKLPIMITENGLGEYDSLTEDHKIHDEYRIEYIRAHALAIQEAITDGVEML
HHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GYCTWSFTDLLSWLNGYQKRYGFVYVDRDENDEKELKRYKKDSFYWYKKTIEANGANLVE
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHCCCEEEEEEEEECCCCHHHH
EQGK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 2841296 [H]