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The map label for this gene is tal1 [H]

Identifier: 226225294

GI number: 226225294

Start: 2788046

End: 2788690

Strand: Reverse

Name: tal1 [H]

Synonym: Lm4b_02717

Alternate gene names: 226225294

Gene position: 2788690-2788046 (Counterclockwise)

Preceding gene: 226225295

Following gene: 226225293

Centisome position: 95.74

GC content: 42.48

Gene sequence:

>645_bases
ATGAGATTTTTTATCGATACAGCGAACGTAGAAGAGATTAAAAAGGCTAACAGAATGGGATTCATTGCCGGAGTCACGAC
AAATCCATCACTTGTTGCAAAAGAAGGTCGCGATTTTAATGAGGTCATTCAAGAAATCACATCCATTGTTGACGGACCGA
TTAGTGGCGAAGTAGTAAGTTTAGAAGCAGATGAGATGATTGCGGAAGGTCGAGTTATTGCAAAAATCCATCCGAATATG
GTTGTAAAGATACCGATGACAGGCGAAGGTTTGGCAGCTGTAAAAGTGTTGACAGAAGAAGGCATTAAAACCAATGTAAC
ACTTGTGTTTTCTGCCACACAGGCCTTGCTTGCAGCACGAGCTGGCGCAACATACGTATCACCGTTTTTAGGTCGATTAG
ATGATATAGGCGACGATGGCTTAGTTCTAATTCGTGACATTGCGGATATTTTCGAGATTCACGGGATTCCAACAGAAATT
ATTTCAGCAAGTGTGCGACACCCAATCCACGTTATTGAATGTGCCAAAGCCGGAGCTGACATTGCTACGGTGCCATTTAA
AGTGTTCGAACAAATGCTAAAACATCCGTTGACCGACAGTGGGATTGACAAATTTCTTGCAGATTGGGAAGCGGCGAAAA
AATAA

Upstream 100 bases:

>100_bases
CTTTTTTTTTGTGGAAAAGCACTTCAAAAGCATTATTTAAATTTTTGCGTTATAATGGCTCTGTAATTGAAAGCGCTTGA
TAGAAAAGGAGGATGTTTTA

Downstream 100 bases:

>100_bases
AGAGGTAGGTTTCTAACTATGAATCAAACATTTATCGTGAAAAAAGAACATGTTAGTCAATATCCAAATCCCCTTTTTGT
GAATAAAAATGAGTCTATTT

Product: putative translaldolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MRFFIDTANVEEIKKANRMGFIAGVTTNPSLVAKEGRDFNEVIQEITSIVDGPISGEVVSLEADEMIAEGRVIAKIHPNM
VVKIPMTGEGLAAVKVLTEEGIKTNVTLVFSATQALLAARAGATYVSPFLGRLDDIGDDGLVLIRDIADIFEIHGIPTEI
ISASVRHPIHVIECAKAGADIATVPFKVFEQMLKHPLTDSGIDKFLADWEAAKK

Sequences:

>Translated_214_residues
MRFFIDTANVEEIKKANRMGFIAGVTTNPSLVAKEGRDFNEVIQEITSIVDGPISGEVVSLEADEMIAEGRVIAKIHPNM
VVKIPMTGEGLAAVKVLTEEGIKTNVTLVFSATQALLAARAGATYVSPFLGRLDDIGDDGLVLIRDIADIFEIHGIPTEI
ISASVRHPIHVIECAKAGADIATVPFKVFEQMLKHPLTDSGIDKFLADWEAAKK
>Mature_214_residues
MRFFIDTANVEEIKKANRMGFIAGVTTNPSLVAKEGRDFNEVIQEITSIVDGPISGEVVSLEADEMIAEGRVIAKIHPNM
VVKIPMTGEGLAAVKVLTEEGIKTNVTLVFSATQALLAARAGATYVSPFLGRLDDIGDDGLVLIRDIADIFEIHGIPTEI
ISASVRHPIHVIECAKAGADIATVPFKVFEQMLKHPLTDSGIDKFLADWEAAKK

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway [H]

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 3B subfamily [H]

Homologues:

Organism=Homo sapiens, GI5803187, Length=174, Percent_Identity=29.8850574712644, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1790382, Length=214, Percent_Identity=40.1869158878505, Blast_Score=150, Evalue=4e-38,
Organism=Escherichia coli, GI87081788, Length=214, Percent_Identity=34.5794392523364, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1786189, Length=171, Percent_Identity=29.8245614035088, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788807, Length=171, Percent_Identity=29.2397660818713, Blast_Score=70, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6321480, Length=173, Percent_Identity=30.635838150289, Blast_Score=75, Evalue=9e-15,
Organism=Drosophila melanogaster, GI45549185, Length=172, Percent_Identity=26.1627906976744, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004731
- InterPro:   IPR022999
- InterPro:   IPR018225 [H]

Pfam domain/function: PF00923 Transaldolase [H]

EC number: =2.2.1.2 [H]

Molecular weight: Translated: 23080; Mature: 23080

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS01054 TRANSALDOLASE_1 ; PS00958 TRANSALDOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFFIDTANVEEIKKANRMGFIAGVTTNPSLVAKEGRDFNEVIQEITSIVDGPISGEVVS
CEEEEECCCHHHHHHHCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCEEE
LEADEMIAEGRVIAKIHPNMVVKIPMTGEGLAAVKVLTEEGIKTNVTLVFSATQALLAAR
EEHHHHHHCCEEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEEHHHHHHHHH
AGATYVSPFLGRLDDIGDDGLVLIRDIADIFEIHGIPTEIISASVRHPIHVIECAKAGAD
CCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCHHHHHHHHCCCHHEEHHHHCCCC
IATVPFKVFEQMLKHPLTDSGIDKFLADWEAAKK
EEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRFFIDTANVEEIKKANRMGFIAGVTTNPSLVAKEGRDFNEVIQEITSIVDGPISGEVVS
CEEEEECCCHHHHHHHCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCEEE
LEADEMIAEGRVIAKIHPNMVVKIPMTGEGLAAVKVLTEEGIKTNVTLVFSATQALLAAR
EEHHHHHHCCEEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEEHHHHHHHHH
AGATYVSPFLGRLDDIGDDGLVLIRDIADIFEIHGIPTEIISASVRHPIHVIECAKAGAD
CCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCHHHHHHHHCCCHHEEHHHHCCCC
IATVPFKVFEQMLKHPLTDSGIDKFLADWEAAKK
EEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]