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The map label for this gene is gmuC [H]

Identifier: 226225260

GI number: 226225260

Start: 2751470

End: 2752834

Strand: Reverse

Name: gmuC [H]

Synonym: Lm4b_02682

Alternate gene names: 226225260

Gene position: 2752834-2751470 (Counterclockwise)

Preceding gene: 226225262

Following gene: 226225259

Centisome position: 94.51

GC content: 39.41

Gene sequence:

>1365_bases
ATGAATGGATTAACAGCATTTTTGGAAAAGTATTTTGTGCCAGTAGCAGCGAAAATTGGTTCACAAAAACATCTAGTTGC
ATTACGTGATGCTTTTATTTCAACAATGCCAATCACTATGGCTGGGTCAATTGCAGTACTTTTAAATGCGTTTTTTAGGG
ATTTTCCAACTGACTGGGGATGGACAGGATTTGTGGAAGCGATGCAACCACTTATCGGGATTAATGGATATGTATACAAT
GGGACATTAGCAATTGTTTCAATTATTTTTGCCTTTTCACTAGGGTATAATTTATCAAAAGCATATGAAGTGGATCGATT
AGCTGGGGGGCTAGTTTCTCTTGCTGCTTTTGTTATGAACTTAACTGTTACTGTAAGCTTAGATGCAGTAAAAGCTGCGA
TTGCGGCTTCTAATGCAAATTTCGATGTAAATACGTTACCAAAAGAATTTGCTGGAATTTACGGATTCTTTAGCCTAAGC
CAAGTAAATGGTACCGGCTTGTTTACCGCAATGATTTTCGGTTTTATATCAACTATTATTTATGCGAAATTAATGCGCAG
AAATATTATTATCAAAATGCCAGATTCTGTTCCACCGGCTGTAAGTAAAGCTTTCGCGGCGATTATTCCTGCGTTAGTTG
CACTTTATGTTGTTGGTATTATTGACTGGGCATTCTTCAAAATCACAAATATGGACGTTATTACTTGGATTTCCAAAACA
ATTCAAGAGCCGTTATTATCACTTTCGCAAGGGTACGGAGCTGTTTTACTAGTTACTTTCTTAGTACAACTACTATGGTT
CTTCGGGATTCATGGTCCGAACGTACTTGCTCCGGTTCTAGAATCACTTTGGGGTACAGCACAACTACAAAACATTAGTG
CGGCACAAGAAGGCGCTAAATTACCATTCGAATGGGTACGTGGTTCTTTCGATGCGTATGTATGGATGGGTGGATCAGGC
GGTACGCTTGTACTGATTATCGCATTACTAATGTTCTCGAAACGAGCGGATGCACGAACAGTTGCGAAATTGTCTCTTGC
ACCAGGTATATTTAATATTAACGAACCAATCATGTTTGGTTTACCGATCGTATTAAATACAATTTACTTAATACCATTCC
TTATCGCGCCAATGGTAATGGTAACAATCGCTTACTTTGCAACAACACTTGGCATTGTCGGCCCAGTTAAAATTGCAGTA
GTTTGGGTAATGCCGCCACTTCTGAATTCCTTCTTAGCAACCGGGGGAGATTGGATGGCACCAGTAATTTCACTCATAAA
TATGGTCGTCGCGTTCTTGATTTGGGTACCATTTGTTATTACCGCAAATCGCGTTGGTGTACCAGAAGAAGAGATGAAAG
CTTAG

Upstream 100 bases:

>100_bases
AACAGATATAGCTGATCAACTTAAAGGGAGTTTATACATAGAAATTATATTTTGTTTAAAAGATGAGTGTTAAATAAAAA
GGTTTACGGGAGGATAAAAT

Downstream 100 bases:

>100_bases
AAAATAATAAGTTTCTGGCTAGGTGCAGCTAAATTGTGCCTAGCCAGTATATCATGTAGGAATTCCTGCACCATTTTTAT
TCATTGCAAGAAGCGAAAGA

Product: PTS system, cellobiose-specific enzyme IIC

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: Glucomannan utilization protein C; PTS system oligo-beta-mannoside-specific EIIC component [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MNGLTAFLEKYFVPVAAKIGSQKHLVALRDAFISTMPITMAGSIAVLLNAFFRDFPTDWGWTGFVEAMQPLIGINGYVYN
GTLAIVSIIFAFSLGYNLSKAYEVDRLAGGLVSLAAFVMNLTVTVSLDAVKAAIAASNANFDVNTLPKEFAGIYGFFSLS
QVNGTGLFTAMIFGFISTIIYAKLMRRNIIIKMPDSVPPAVSKAFAAIIPALVALYVVGIIDWAFFKITNMDVITWISKT
IQEPLLSLSQGYGAVLLVTFLVQLLWFFGIHGPNVLAPVLESLWGTAQLQNISAAQEGAKLPFEWVRGSFDAYVWMGGSG
GTLVLIIALLMFSKRADARTVAKLSLAPGIFNINEPIMFGLPIVLNTIYLIPFLIAPMVMVTIAYFATTLGIVGPVKIAV
VWVMPPLLNSFLATGGDWMAPVISLINMVVAFLIWVPFVITANRVGVPEEEMKA

Sequences:

>Translated_454_residues
MNGLTAFLEKYFVPVAAKIGSQKHLVALRDAFISTMPITMAGSIAVLLNAFFRDFPTDWGWTGFVEAMQPLIGINGYVYN
GTLAIVSIIFAFSLGYNLSKAYEVDRLAGGLVSLAAFVMNLTVTVSLDAVKAAIAASNANFDVNTLPKEFAGIYGFFSLS
QVNGTGLFTAMIFGFISTIIYAKLMRRNIIIKMPDSVPPAVSKAFAAIIPALVALYVVGIIDWAFFKITNMDVITWISKT
IQEPLLSLSQGYGAVLLVTFLVQLLWFFGIHGPNVLAPVLESLWGTAQLQNISAAQEGAKLPFEWVRGSFDAYVWMGGSG
GTLVLIIALLMFSKRADARTVAKLSLAPGIFNINEPIMFGLPIVLNTIYLIPFLIAPMVMVTIAYFATTLGIVGPVKIAV
VWVMPPLLNSFLATGGDWMAPVISLINMVVAFLIWVPFVITANRVGVPEEEMKA
>Mature_454_residues
MNGLTAFLEKYFVPVAAKIGSQKHLVALRDAFISTMPITMAGSIAVLLNAFFRDFPTDWGWTGFVEAMQPLIGINGYVYN
GTLAIVSIIFAFSLGYNLSKAYEVDRLAGGLVSLAAFVMNLTVTVSLDAVKAAIAASNANFDVNTLPKEFAGIYGFFSLS
QVNGTGLFTAMIFGFISTIIYAKLMRRNIIIKMPDSVPPAVSKAFAAIIPALVALYVVGIIDWAFFKITNMDVITWISKT
IQEPLLSLSQGYGAVLLVTFLVQLLWFFGIHGPNVLAPVLESLWGTAQLQNISAAQEGAKLPFEWVRGSFDAYVWMGGSG
GTLVLIIALLMFSKRADARTVAKLSLAPGIFNINEPIMFGLPIVLNTIYLIPFLIAPMVMVTIAYFATTLGIVGPVKIAV
VWVMPPLLNSFLATGGDWMAPVISLINMVVAFLIWVPFVITANRVGVPEEEMKA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=473, Percent_Identity=37.2093023255814, Blast_Score=261, Evalue=5e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 49166; Mature: 49166

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]